DE3579750D1 - Verfahren zur herstellung von 16,17-acetal von pregnanderivaten und die erhaltene verbindungen. - Google Patents

Verfahren zur herstellung von 16,17-acetal von pregnanderivaten und die erhaltene verbindungen.

Info

Publication number
DE3579750D1
DE3579750D1 DE8585106522T DE3579750T DE3579750D1 DE 3579750 D1 DE3579750 D1 DE 3579750D1 DE 8585106522 T DE8585106522 T DE 8585106522T DE 3579750 T DE3579750 T DE 3579750T DE 3579750 D1 DE3579750 D1 DE 3579750D1
Authority
DE
Germany
Prior art keywords
pregnane derivatives
acetal
producing
obtained compounds
acetals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585106522T
Other languages
German (de)
English (en)
Inventor
Peter Macdonald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
SICOR Societa Italiana Corticosteroidi SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11180389&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3579750(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SICOR Societa Italiana Corticosteroidi SRL filed Critical SICOR Societa Italiana Corticosteroidi SRL
Application granted granted Critical
Publication of DE3579750D1 publication Critical patent/DE3579750D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
DE8585106522T 1984-06-11 1985-05-28 Verfahren zur herstellung von 16,17-acetal von pregnanderivaten und die erhaltene verbindungen. Expired - Lifetime DE3579750D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21343/84A IT1196142B (it) 1984-06-11 1984-06-11 Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti

Publications (1)

Publication Number Publication Date
DE3579750D1 true DE3579750D1 (de) 1990-10-25

Family

ID=11180389

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585106522T Expired - Lifetime DE3579750D1 (de) 1984-06-11 1985-05-28 Verfahren zur herstellung von 16,17-acetal von pregnanderivaten und die erhaltene verbindungen.

Country Status (11)

Country Link
US (2) US4695625A (enExample)
EP (1) EP0164636B1 (enExample)
JP (1) JPS6140299A (enExample)
AT (1) ATE56725T1 (enExample)
CA (1) CA1336513C (enExample)
DE (1) DE3579750D1 (enExample)
DK (1) DK163433C (enExample)
ES (1) ES8705462A1 (enExample)
FI (1) FI81809C (enExample)
IT (1) IT1196142B (enExample)
NO (1) NO164905C (enExample)

Families Citing this family (55)

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IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
JPS6369953A (ja) * 1986-09-11 1988-03-30 Kobe Steel Ltd 方向性の優れたアルミニウム合金の製造法
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JPH01129688A (ja) * 1987-11-16 1989-05-22 Mitsubishi Electric Corp 画像信号受信装置
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PL164294B1 (pl) * 1990-12-20 1994-07-29 Inst Farmaceutyczny Sposób otrzymywania diastereoizomeru /22R/-16a , 17a-butylidenodioksy-11 ß 21-dihydroksy-1,4-pregnadien-3,20-dionu PL
SE9100342D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroid esters
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
US5888995A (en) * 1991-02-04 1999-03-30 Astra Aktiebolag Steroid esters
DE59407183D1 (de) * 1993-04-02 1998-12-03 Byk Gulden Lomberg Chem Fab Neue prednisolonderivate
GB9423919D0 (en) * 1994-11-26 1995-01-11 Rhone Poulenc Rorer Ltd Chemical process
DE19635498A1 (de) * 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung
IT1291288B1 (it) * 1997-04-30 1999-01-07 Farmabios Srl Processo per la preparazione di 16,17 acetali di derivati pregnanici con controllo della distribuzione epimerica al c-22.
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6266556B1 (en) 1998-04-27 2001-07-24 Beth Israel Deaconess Medical Center, Inc. Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation
IT1302657B1 (it) * 1998-10-13 2000-09-29 Farmabios Srl Processo stereoselettivo per la preparazione di budesonide nella formadi epimero 22-r.
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
US6883516B2 (en) 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
MY136453A (en) 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
BR0015884A (pt) 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
CN1264855C (zh) * 2000-11-10 2006-07-19 奥坦纳医药公司 通过转缩酮化生产16,17－[（环己基亚甲基)双(氧基)]－11,21－二羟－孕－1,4－二烯－3,20－二酮或其21－异丁酸酯的方法
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US7077130B2 (en) 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
ATE267591T1 (de) * 2001-07-02 2004-06-15 Chiesi Farma Spa Optimierte tobramycin-formulierung zur aerosolbildung
EP1275656A1 (en) * 2001-07-11 2003-01-15 Genchem Pharma Limited Preparation of 9alpha-fluoro-11beta-hydroxypregnane 16,17-acetal derivatives
KR100923804B1 (ko) * 2001-09-03 2009-10-27 파나소닉 주식회사 반도체발광소자, 발광장치 및 반도체발광소자의 제조방법
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6804458B2 (en) 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
KR100947409B1 (ko) * 2002-03-01 2010-03-12 키에시 파르마슈티시 엣스. 피. 에이. 포모테롤 초미세 조성물
US20040235811A1 (en) 2002-10-08 2004-11-25 Sepracor Inc. Fatty acid modified forms of glucocorticoids
US7367334B2 (en) 2003-08-27 2008-05-06 Philip Morris Usa Inc. Fluid vaporizing device having controlled temperature profile heater/capillary tube
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
WO2007054974A2 (en) * 2005-09-28 2007-05-18 Arch Pharmalab Limited A green chemistry process for the preparation of pregnadiene esters
JP2009512733A (ja) * 2005-11-02 2009-03-26 シコール インコーポレイティド シクレソニドの改良された製造法
US20070232578A1 (en) * 2006-02-15 2007-10-04 Pierluigi Rossetto Crystalline forms of ciclesonide
ITMI20080645A1 (it) * 2008-04-11 2009-10-12 Ind Chimica Srl Procedimento per la preparazione di budesonide
CN101279997B (zh) * 2008-05-29 2011-08-24 鲁南制药集团股份有限公司 布地奈德的一种制备方法
CN101863952B (zh) * 2010-04-30 2013-04-17 湖北葛店人福药业有限责任公司 布地奈德的制备方法
CN102060906B (zh) * 2010-12-23 2013-01-16 鲁南贝特制药有限公司 一种r布地奈德的制备方法
EP3250211B1 (en) 2015-01-30 2021-12-22 Coral Drugs Pvt. Ltd. Novel process for preparation of glucocorticoid steroids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE378110B (enExample) * 1972-05-19 1975-08-18 Bofors Ab
US3996359A (en) * 1972-05-19 1976-12-07 Ab Bofors Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
SE378109B (enExample) * 1972-05-19 1975-08-18 Bofors Ab
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
DK176716B1 (da) * 2007-09-03 2009-04-14 Viking Life Saving Equip As Redningsflådesystem

Also Published As

Publication number Publication date
US4835145A (en) 1989-05-30
DK163433C (da) 1992-07-27
IT1196142B (it) 1988-11-10
NO852327L (no) 1985-12-12
JPH0213680B2 (enExample) 1990-04-04
FI81809C (fi) 1990-12-10
ATE56725T1 (de) 1990-10-15
EP0164636A2 (en) 1985-12-18
FI81809B (fi) 1990-08-31
DK163433B (da) 1992-03-02
CA1336513C (en) 1995-08-01
FI852093L (fi) 1985-12-12
FI852093A0 (fi) 1985-05-24
ES8705462A1 (es) 1987-05-01
DK243085A (da) 1985-12-12
US4695625A (en) 1987-09-22
JPS6140299A (ja) 1986-02-26
ES543499A0 (es) 1987-05-01
IT8421343A1 (it) 1985-12-11
NO164905B (no) 1990-08-20
EP0164636A3 (en) 1986-10-08
DK243085D0 (da) 1985-05-30
EP0164636B1 (en) 1990-09-19
NO164905C (no) 1990-11-28
IT8421343A0 (it) 1984-06-11

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: AKTIEBOLAGET ASTRA, SOEDERTAELJE, SE