DE3407979A1 - Spicamycin sowie verfahren zu seiner herstellung - Google Patents
Spicamycin sowie verfahren zu seiner herstellungInfo
- Publication number
- DE3407979A1 DE3407979A1 DE19843407979 DE3407979A DE3407979A1 DE 3407979 A1 DE3407979 A1 DE 3407979A1 DE 19843407979 DE19843407979 DE 19843407979 DE 3407979 A DE3407979 A DE 3407979A DE 3407979 A1 DE3407979 A1 DE 3407979A1
- Authority
- DE
- Germany
- Prior art keywords
- spicamycin
- antibiotic
- properties
- methanol
- absorption spectrum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 238000000034 method Methods 0.000 title claims description 16
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- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- LWIHDJKSTIGBAC-UHFFFAOYSA-K potassium phosphate Substances [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 208000019585 progressive encephalomyelitis with rigidity and myoclonus Diseases 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000004317 sodium nitrate Substances 0.000 description 1
- 235000010344 sodium nitrate Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 241001446247 uncultured actinomycete Species 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58035662A JPS59161396A (ja) | 1983-03-04 | 1983-03-04 | 新規抗生物質スピカマイシン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3407979A1 true DE3407979A1 (de) | 1984-09-06 |
| DE3407979C2 DE3407979C2 (en, 2012) | 1993-09-16 |
Family
ID=12448078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19843407979 Granted DE3407979A1 (de) | 1983-03-04 | 1984-03-03 | Spicamycin sowie verfahren zu seiner herstellung |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4565781A (en, 2012) |
| JP (1) | JPS59161396A (en, 2012) |
| DE (1) | DE3407979A1 (en, 2012) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990015811A1 (en) * | 1989-06-16 | 1990-12-27 | Kirin Beer Kabushiki Kaisha | Spicamycin x and its use |
| EP0525479A1 (en) * | 1991-07-12 | 1993-02-03 | Kirin Beer Kabushiki Kaisha | Spicamycin derivatives and the use thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05279374A (ja) * | 1992-03-31 | 1993-10-26 | Sawao Murao | スイダトレスチン及びその製造方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3264195A (en) * | 1963-07-24 | 1966-08-02 | Squibb & Sons Inc | Process for the preparation of septacidin and derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3155647A (en) * | 1963-07-24 | 1964-11-03 | Olin Mathieson | Septaciding and derivatives thereof |
| US4086416A (en) * | 1977-05-17 | 1978-04-25 | Stanford Research Institute | Septacidin analogs |
-
1983
- 1983-03-04 JP JP58035662A patent/JPS59161396A/ja active Granted
-
1984
- 1984-02-24 US US06/583,108 patent/US4565781A/en not_active Expired - Lifetime
- 1984-03-03 DE DE19843407979 patent/DE3407979A1/de active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3264195A (en) * | 1963-07-24 | 1966-08-02 | Squibb & Sons Inc | Process for the preparation of septacidin and derivatives |
Non-Patent Citations (1)
| Title |
|---|
| Journal of Medicinal Chemistry, 1977, 20, 11, S. 1362-1371 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990015811A1 (en) * | 1989-06-16 | 1990-12-27 | Kirin Beer Kabushiki Kaisha | Spicamycin x and its use |
| EP0525479A1 (en) * | 1991-07-12 | 1993-02-03 | Kirin Beer Kabushiki Kaisha | Spicamycin derivatives and the use thereof |
| US5461036A (en) * | 1991-07-12 | 1995-10-24 | Kirin Beer Kabushiki Kaisha | Spicamycin derivatives and their use as anticancer agents |
| US5631238A (en) * | 1991-07-12 | 1997-05-20 | Kirin Beer Kabushiki Kaisha | Spicamycin derivatives and the use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3407979C2 (en, 2012) | 1993-09-16 |
| JPS59161396A (ja) | 1984-09-12 |
| JPH0367077B2 (en, 2012) | 1991-10-21 |
| US4565781A (en) | 1986-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition |