DE3364299D1 - Pulverized mixture of lipid and hydrophobic constituents, process for preparing them, hydrated lipid lamellar phases and process for preparing them, pharmaceutical or cosmetic compositions containing hydrated lamellar lipid phases - Google Patents

Pulverized mixture of lipid and hydrophobic constituents, process for preparing them, hydrated lipid lamellar phases and process for preparing them, pharmaceutical or cosmetic compositions containing hydrated lamellar lipid phases

Info

Publication number
DE3364299D1
DE3364299D1 DE8383400281T DE3364299T DE3364299D1 DE 3364299 D1 DE3364299 D1 DE 3364299D1 DE 8383400281 T DE8383400281 T DE 8383400281T DE 3364299 T DE3364299 T DE 3364299T DE 3364299 D1 DE3364299 D1 DE 3364299D1
Authority
DE
Germany
Prior art keywords
lipid
preparing
phases
hydrated
lamellar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383400281T
Other languages
German (de)
English (en)
Inventor
Gerard Redziniak
Alain Meybeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parfums Christian Dior SA
Original Assignee
Parfums Christian Dior SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9271079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3364299(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Parfums Christian Dior SA filed Critical Parfums Christian Dior SA
Application granted granted Critical
Publication of DE3364299D1 publication Critical patent/DE3364299D1/de
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/982Reproductive organs; Embryos, Eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14Liposomes; Vesicles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/001Preparations for care of the lips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/829Liposomes, e.g. encapsulation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE8383400281T 1982-02-17 1983-02-09 Pulverized mixture of lipid and hydrophobic constituents, process for preparing them, hydrated lipid lamellar phases and process for preparing them, pharmaceutical or cosmetic compositions containing hydrated lamellar lipid phases Expired DE3364299D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8202620A FR2521565B1 (fr) 1982-02-17 1982-02-17 Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees

Publications (1)

Publication Number Publication Date
DE3364299D1 true DE3364299D1 (en) 1986-08-07

Family

ID=9271079

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8383400281T Expired DE3364299D1 (en) 1982-02-17 1983-02-09 Pulverized mixture of lipid and hydrophobic constituents, process for preparing them, hydrated lipid lamellar phases and process for preparing them, pharmaceutical or cosmetic compositions containing hydrated lamellar lipid phases
DE198383400281T Pending DE87993T1 (de) 1982-02-17 1983-02-09 Pulverfoermige mischung von lipiden und hydrophoben bestandteilen, verfahren zu deren herstellung, hydratierte lamellare lipide phasen und verfahren zur herstellung, pharmazeutische oder kosmetische mittel die hydratierte lamellare lipide phasen enthalten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198383400281T Pending DE87993T1 (de) 1982-02-17 1983-02-09 Pulverfoermige mischung von lipiden und hydrophoben bestandteilen, verfahren zu deren herstellung, hydratierte lamellare lipide phasen und verfahren zur herstellung, pharmazeutische oder kosmetische mittel die hydratierte lamellare lipide phasen enthalten.

Country Status (13)

Country Link
US (1) US4508703A (cg-RX-API-DMAC7.html)
EP (1) EP0087993B2 (cg-RX-API-DMAC7.html)
JP (1) JPS5931707A (cg-RX-API-DMAC7.html)
AT (1) ATE20574T1 (cg-RX-API-DMAC7.html)
CA (1) CA1208133A (cg-RX-API-DMAC7.html)
DE (2) DE3364299D1 (cg-RX-API-DMAC7.html)
DK (1) DK67783A (cg-RX-API-DMAC7.html)
ES (1) ES519878A0 (cg-RX-API-DMAC7.html)
FR (1) FR2521565B1 (cg-RX-API-DMAC7.html)
GR (1) GR77128B (cg-RX-API-DMAC7.html)
HK (1) HK85287A (cg-RX-API-DMAC7.html)
IL (1) IL67939A0 (cg-RX-API-DMAC7.html)
SG (1) SG55887G (cg-RX-API-DMAC7.html)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2135647A (en) * 1983-02-15 1984-09-05 Squibb & Sons Inc Method of preparing liposomes and products produced thereby
JPS6058915A (ja) * 1983-09-12 1985-04-05 Fujisawa Pharmaceut Co Ltd 薬物含有脂質小胞体製剤
JPS60155109A (ja) * 1984-01-23 1985-08-15 Terumo Corp リポソ−ム製剤
US4744989A (en) * 1984-02-08 1988-05-17 E. R. Squibb & Sons, Inc. Method of preparing liposomes and products produced thereby
GB8613811D0 (en) * 1986-06-06 1986-07-09 Phares Pharm Res Nv Composition & method
US5141674A (en) * 1984-03-08 1992-08-25 Phares Pharmaceutical Research N.V. Methods of preparing pro-liposome dispersions and aerosols
US5231112A (en) 1984-04-12 1993-07-27 The Liposome Company, Inc. Compositions containing tris salt of cholesterol hemisuccinate and antifungal
US4891208A (en) * 1985-04-10 1990-01-02 The Liposome Company, Inc. Steroidal liposomes
GB8423436D0 (en) * 1984-09-17 1984-10-24 Riker Laboratories Inc Preparation of liposomes
US4830858A (en) * 1985-02-11 1989-05-16 E. R. Squibb & Sons, Inc. Spray-drying method for preparing liposomes and products produced thereby
JPH0676308B2 (ja) * 1985-06-18 1994-09-28 ポーラ化成工業株式会社 皮膚外用剤
US4683092A (en) * 1985-07-03 1987-07-28 Damon Biotech, Inc. Capsule loading technique
US5230899A (en) * 1985-08-07 1993-07-27 Smithkline Beecham Corporation Methods and compositions for making liposomes
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol
ATE71540T1 (de) * 1985-10-21 1992-02-15 Liposome Co Inc In situ-herstellung und verabreichung von liposomen.
FR2591105B1 (fr) 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
JPS62152531A (ja) * 1985-12-26 1987-07-07 Dai Ichi Seiyaku Co Ltd リポソ−ムの製造法
EP0321457A1 (en) * 1986-01-13 1989-06-28 Research Corporation Aqueous dispersions of waxes and lipids for pharmaceutical coating
US5023108A (en) * 1986-01-13 1991-06-11 Research Corporation Aqueous dispersions of waxes and lipids for pharmaceutical coating
US4737323A (en) * 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
FR2597345B1 (fr) * 1986-04-22 1990-08-03 Oreal Composition cosmetique ou pharmaceutique a base d'une dispersion aqueuse de spherules lipidiques.
US4781871A (en) * 1986-09-18 1988-11-01 Liposome Technology, Inc. High-concentration liposome processing method
WO1988001864A1 (en) * 1986-09-18 1988-03-24 Liposome Technology, Inc. High-concentration liposome processing method
WO1988003797A1 (en) * 1986-11-28 1988-06-02 The Liposome Company, Inc. Phospholipid composition
JPS63182029A (ja) * 1987-01-22 1988-07-27 Agency Of Ind Science & Technol リポソ−ム
AU604288B2 (en) * 1987-01-26 1990-12-13 Vestar, Inc. Phospholipid delivery vehicle for aqueous-insoluble active ingredients
CA1321351C (en) * 1987-02-23 1993-08-17 Helmut Otmar Hauser Method of dehydrating vesicle preparations for long-term storage
US5089181A (en) * 1987-02-24 1992-02-18 Vestar, Inc. Method of dehydrating vesicle preparations for long term storage
NZ223660A (en) * 1987-03-05 1990-11-27 Liposome Co Inc Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity
US6406713B1 (en) 1987-03-05 2002-06-18 The Liposome Company, Inc. Methods of preparing low-toxicity drug-lipid complexes
US5616334A (en) * 1987-03-05 1997-04-01 The Liposome Company, Inc. Low toxicity drug-lipid systems
IT1223290B (it) * 1987-07-27 1990-09-19 Indena Spa Acidi poliinsaturi ad azione vasocinetica e relative formulazioni farmaceutiche e cosmetiche
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
FR2619505B1 (fr) * 1987-08-20 1990-08-31 Dior Christian Parfums Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la pregnenolone ou un ester de pregnenolone, et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite regeneratrice ou revitalisante, l'incorporant
US4950432A (en) * 1987-10-16 1990-08-21 Board Of Regents, The University Of Texas System Polyene microlide pre-liposomal powders
US5057497A (en) * 1987-11-10 1991-10-15 Calam & Associates, Inc. Oral method for the maintenance of healthy gingival tissues using TRF
US5290562A (en) * 1987-11-27 1994-03-01 L V M H Recherche Compositions and methods employing liposomes including tyrosine or a tyrosine derivative
FR2623716B1 (fr) * 1987-11-27 1991-04-05 Lvmh Rech Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la tyrosine ou un derive de tyrosine et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite pigmentante, l'incorporant
US5160669A (en) * 1988-03-03 1992-11-03 Micro Vesicular Systems, Inc. Method of making oil filled paucilamellar lipid vesicles
US5269979A (en) * 1988-06-08 1993-12-14 Fountain Pharmaceuticals, Inc. Method for making solvent dilution microcarriers
US5133965A (en) * 1988-06-08 1992-07-28 Fountain Pharmaceuticals, Inc. Dressing material having adsorbed thereon a solvent dilution microcarrier precursor solution
IL90561A (en) * 1988-06-08 1993-08-18 Fountain Pharm Inc Method for making solvent dilution microcarriers
FR2633516B1 (fr) * 1988-06-30 1991-03-29 Clarins Composition cosmetique pour le traitement des peaux sensibles deshydratees
US5096629A (en) * 1988-08-29 1992-03-17 501 Nippon Fine Chemical Co., Ltd. Method for preparing lipid powder for use in preparing liposomes and method for preparing liposomes
FR2637182B1 (fr) * 1988-10-03 1992-11-06 Lvmh Rech Compositions a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un ecdysteroide, de preference l'ecdysterone, ou l'un de ses derives; et compositions cosmetiques, pharmaceutiques, notamment dermatologiques, de sericulture ou phytosanitaires l'incorporant
US5015483A (en) * 1989-02-09 1991-05-14 Nabisco Brands, Inc. Liposome composition for the stabilization of oxidizable substances
US5139803A (en) * 1989-02-09 1992-08-18 Nabisco, Inc. Method and liposome composition for the stabilization of oxidizable substances
US5277914A (en) * 1989-03-31 1994-01-11 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
US5549910A (en) * 1989-03-31 1996-08-27 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
US5077057A (en) * 1989-04-05 1991-12-31 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
FR2648462B1 (fr) * 1989-06-15 1994-01-28 Oreal Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede
US5174988A (en) * 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
US5246918A (en) * 1990-07-11 1993-09-21 Unilever Patent Holdings B.V. Process for preparing perfumed personal products
EP0466237B1 (en) * 1990-07-11 1994-03-23 Quest International B.V. Stabilized emulsion systems
EP0466236B1 (en) * 1990-07-11 1994-08-17 Quest International B.V. Perfumed structured emulsions in personal products
FR2673840A1 (fr) * 1991-03-14 1992-09-18 Lvmh Rech Composition cosmetique ou pharmaceutique, notamment dermatologique, contenant de l'oxyacanthine, en particulier destinee a stimuler la pousse des cheveux ou a retarder leur chute.
US5498420A (en) * 1991-04-12 1996-03-12 Merz & Co. Gmbh & Co. Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions
FR2681781A1 (fr) 1991-09-30 1993-04-02 Oreal Composition cosmetique anhydre de maquillage comprenant une phase grasse et procede de traitement cosmetique utilisant cette composition.
FR2735658B1 (fr) * 1995-06-21 1997-09-12 Capsulis Encapsulation de composes a usage alimentaire par des tensioactifs
CA2087691A1 (en) * 1992-01-23 1993-07-24 Peter Critchley Cosmetic compositon
GB9208339D0 (en) * 1992-04-15 1992-06-03 Unilever Plc Treatment composition
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
FR2695035A1 (fr) * 1992-08-25 1994-03-04 Lvmh Rech Gie Utilisation d'un ecdystéroïde pour la préparation de compositions cosmétiques ou dermatologiques destinées notamment à renforcer la fonction protectrice de la peau, et compositions ainsi obtenues.
US5958449A (en) * 1992-12-02 1999-09-28 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for bacterial infections
AU3244393A (en) * 1992-12-02 1994-06-22 Vestar, Inc. Antibiotic formulation and process
FR2699080B1 (fr) * 1992-12-11 1995-04-07 Lvmh Rech Utilisation d'un extrait de Simarouba pour l'atténuation des taches pigmentaires cutanées ou pour renforcer la fonction protectrice de la peau, ou pour la préparation d'un milieu de culture de cellules de peau, et composition ainsi obtenue.
FR2699081B1 (fr) 1992-12-11 1995-04-07 Lvmh Rech Utilisation d'un extrait de Simaba pour l'atténuation des taches pigmentaires cutanées ou pour renforcer la fonction protectrice de la peau, ou pour la préparation d'un milieu de culture de cellules de peau, et composition ainsi obtenue.
US5759571A (en) * 1993-05-11 1998-06-02 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for drug resistant infections
US5554382A (en) * 1993-05-28 1996-09-10 Aphios Corporation Methods and apparatus for making liposomes
CA2163860A1 (en) * 1993-06-30 1995-01-12 Chung C. Hsu Method for preparing liposomes
DE4430592A1 (de) * 1994-08-20 1996-02-22 Max Delbrueck Centrum Liposomale Zubereitung, ihre Herstellung und ihre Verwendung
US5702722A (en) * 1994-09-30 1997-12-30 Bracco Research S.A. Liposomes with enhanced entrapment capacity, method and use
CH689139A5 (de) * 1995-04-03 1998-10-30 Cerbios Pharma Sa Verfahren zur Herstellung einer liposomalen, in Wasser dispergierbaren, oral zu verabreichenden, festen, trockenen therapeutischen Formulierung.
US20030032610A1 (en) * 1996-06-03 2003-02-13 Gilchrest Barbara A. Method to inhibit cell growth using oligonucleotides
US7094766B1 (en) 1995-06-06 2006-08-22 Trustees Of Boston University Use of locally applied DNA fragments
US6147056A (en) * 1995-06-06 2000-11-14 Trustees Of Boston University Use of locally applied DNA fragments
US5891467A (en) 1997-01-31 1999-04-06 Depotech Corporation Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
IN187860B (cg-RX-API-DMAC7.html) * 1997-08-27 2002-07-06 Revlon Consumer Prod Corp
US6287590B1 (en) * 1997-10-02 2001-09-11 Esperion Therapeutics, Inc. Peptide/lipid complex formation by co-lyophilization
US5932562A (en) * 1998-05-26 1999-08-03 Washington University Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same
DE59903869D1 (de) * 1998-10-14 2003-01-30 Cognis Deutschland Gmbh Verwendung von nanoskaligen sterolen und sterolestern
FR2787322B1 (fr) * 1998-12-18 2002-10-18 Galderma Res & Dev Emulsion huile-dans-eau comprenant un agent actif micronise et un systeme emulsionnant approprie
US6080211A (en) * 1999-02-19 2000-06-27 Igen, Inc. Lipid vesicle-based fuel additives and liquid energy sources containing same
ES2248082T3 (es) * 1999-06-25 2006-03-16 Cognis Ip Management Gmbh Empleo de esteroles y esteres de esterol nanometricos.
EP2363133A1 (en) * 2000-03-31 2011-09-07 Trustees of Boston University Composition comprising DNA fragments and medical and cosmetic uses thereof
US8658202B2 (en) 2001-04-25 2014-02-25 Western University Of Health Sciences Coated drug delivery formulations
US6759058B1 (en) * 2001-04-25 2004-07-06 Western Center For Drug Development College Of Pharmacy Western University Of Health Sciences Enteric-coated proliposomal formulations for poorly water soluble drugs
BRPI0105509B8 (pt) 2001-11-05 2021-05-25 Univ Minas Gerais formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga
US20050129722A1 (en) * 2002-03-13 2005-06-16 Collagenex Pharmaceuticals, Inc. Water-based delivery systems
ES2411656T3 (es) * 2002-03-13 2013-07-08 Thomas SKÖLD Sistemas de administración a base de agua
US20030212046A1 (en) * 2002-05-07 2003-11-13 Kapac, Llc Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs
US20060093661A1 (en) 2002-05-07 2006-05-04 Kapac, Llc Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs
JP4773720B2 (ja) * 2002-06-12 2011-09-14 ザ・コカ−コーラ・カンパニー 植物ステロール含有飲料
US7306819B2 (en) * 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
US20060269924A1 (en) * 2003-04-11 2006-11-30 Trustees Of Boston University Modulation of telomere-initiated cell signaling
JP2007512334A (ja) * 2003-11-20 2007-05-17 ゾマネックス,エルエルシー ジヒドロテストステロンの上昇に関連した病状を治療するための方法および製剤
WO2005113764A2 (en) 2004-05-19 2005-12-01 Trustees Of Boston University Modulation of wrn-mediated telomere-initiated cell signaling
PL1835922T3 (pl) * 2004-12-22 2009-10-30 Merck Serono Sa Terapia skojarzona stwardnienia rozsianego
ES2275443B1 (es) 2005-11-30 2008-06-01 Italfarmaco, S.A. Procedimiento de preparacion de liposomas.
JP2007261984A (ja) * 2006-03-28 2007-10-11 Konica Minolta Medical & Graphic Inc 脂肪酸エステルを有するリポソ−ムおよびその製剤
US8007790B2 (en) 2006-04-03 2011-08-30 Stowers Institute For Medical Research Methods for treating polycystic kidney disease (PKD) or other cyst forming diseases
JP5502480B2 (ja) 2006-09-18 2014-05-28 コンピュゲン エルティーディー. 生物活性ペプチド及びその使用方法
US20080124387A1 (en) 2006-11-27 2008-05-29 Kapac, Llc Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients
GB0623838D0 (en) * 2006-11-29 2007-01-10 Malvern Cosmeceutics Ltd Novel compositions
US20080207711A1 (en) * 2007-02-28 2008-08-28 Rong Li Method for treating an ID2-related disorder
AU2008273813B2 (en) 2007-07-12 2013-06-13 Compugen Ltd. Bioactive peptides and method of using same
US20090088393A1 (en) * 2007-09-28 2009-04-02 Zomanex, Llc Methods and formulations for converting intravenous and injectable drugs into oral dosage forms
EA017385B1 (ru) 2007-10-16 2012-12-28 Репрос Терапьютикс Инк. Применение транс-кломифена для снижения концентрации глюкозы в сыворотке
US8101606B2 (en) * 2007-11-12 2012-01-24 Washington University Neurofibromin pathway modulators
WO2009076323A2 (en) 2007-12-06 2009-06-18 Genalyte Inc. Monitoring enzymatic process
TWI477276B (zh) 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
TWI539953B (zh) 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
ES2939310T3 (es) 2008-10-27 2023-04-20 Genalyte Inc Biosensores basados en sondeo y detección ópticos
CA2781527C (en) 2009-09-23 2017-10-24 Indu Javeri Methods for the preparation of liposomes
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
CN102906103A (zh) 2010-03-22 2013-01-30 利普生物药剂公司 用于抗孕酮的非毒性递送的组合物和方法
CN104959052B (zh) 2010-04-09 2018-07-13 帕西拉制药有限公司 用于配制大直径合成膜囊泡的方法
EP2635710B1 (en) 2010-11-05 2017-08-09 Genalyte, Inc. Optical analyte detection systems and methods of use
UA113283C2 (xx) 2010-12-23 2017-01-10 19-норстероїди і їх застосування для лікування прогестеронзалежних станів
WO2012109387A1 (en) 2011-02-08 2012-08-16 Halozyme, Inc. Composition and lipid formulation of a hyaluronan-degrading enzyme and the use thereof for treatment of benign prostatic hyperplasia
EP3907506A1 (en) 2012-03-12 2021-11-10 The Board of Trustees of the University of Illinois Optical analyte detection systems with magnetic enhancement and methods of their use
MX363640B (es) 2012-05-31 2019-03-28 Repros Therapeutics Inc Formulaciones y metodos para la administracion vaginal de antiprogestinas.
US9545411B2 (en) 2012-11-02 2017-01-17 Repros Therapeutics Inc. Methods and compositions for treating progesterone-dependent conditions
DK3186281T3 (da) 2014-08-28 2019-06-11 Halozyme Inc Kombinationsterapi med et hyaluronan-nedbrydende enzym og en immun-checkpoint-inhibitor
WO2016118281A1 (en) 2015-01-20 2016-07-28 TetraDerm Group LLC Versatile topical drug delivery vehicle and multifactorial tissue moisturizer that provides mucosal and skin barrier restoration
US11376218B2 (en) 2015-05-04 2022-07-05 Versantis AG Method for preparing transmembrane pH-gradient vesicles
EP3650546A1 (en) 2015-07-29 2020-05-13 IFOM Fondazione Istituto Firc di Oncologia Molecolare Therapeutic oligonucleotides
EP3124609A1 (en) 2015-07-29 2017-02-01 IFOM Fondazione Istituto Firc di Oncologia Molecolare Therapeutics oligonucleotides
WO2017027622A1 (en) 2015-08-11 2017-02-16 Scintillon Institute For Biomedical And Bioenergy Research Optical analyses of particles and vesicles
ITUA20161994A1 (it) 2016-03-24 2017-09-24 Azienda Ospedaliera Univ Senese Uso degli inibitori ddx3 come agenti anti-iperproliferativi
EP3493790A4 (en) 2016-08-02 2020-03-25 Curirx Inc. LIPOSOME PREPARATION METHODS
JP2020506904A (ja) 2017-01-27 2020-03-05 シグナルアールエックス ファーマシューティカルズ,インコーポレイテッド キナーゼ、ブロモドメイン及びチェックポイント阻害剤としてのチエノピラノン及びフラノピラノン
US20210300939A1 (en) 2018-07-23 2021-09-30 Signalrx Pharmaceuticals, Inc. Single Molecule Compounds Providing Multi-Target Inhibition of BTK and Other Proteins and Methods of Use Thereof
MX2021002882A (es) 2018-09-12 2021-07-16 Broad Inst Inc Focalizacion de egln1 en el cancer.
EP4050002A1 (en) 2021-02-26 2022-08-31 First Health Pharmaceuticals B.V. Anti-proliferative agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL112870C (cg-RX-API-DMAC7.html) * 1959-04-15
US3499962A (en) * 1967-08-24 1970-03-10 Nat Starch Chem Corp Encapsulation of water insoluble materials
CA1047924A (en) * 1973-10-30 1979-02-06 Kyowa Hakko Kogyo Co. Powdered emulsion product and method of production
FR2315991A1 (fr) * 1975-06-30 1977-01-28 Oreal Procede de fabrication de dispersions aqueuses de spherules lipidiques et nouvelles compositions correspondantes
IN147123B (cg-RX-API-DMAC7.html) * 1976-10-19 1979-11-17 Standard Oil Co Ohio
US4235792A (en) * 1977-04-14 1980-11-25 The Governing Council Of The University Of Toronto Immunological materials
CH621479A5 (cg-RX-API-DMAC7.html) * 1977-08-05 1981-02-13 Battelle Memorial Institute
IT1110989B (it) * 1979-01-19 1986-01-13 Erba Farmitalia Forme farmaceutiche costitutite da liposomi e procedimenti relativi
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
GB1575344A (en) * 1978-03-03 1980-09-17 Ici Ltd Method for the manufacture of liposome composition
HU184141B (en) * 1979-12-27 1984-07-30 Human Oltoanyagtermelo Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof

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HK85287A (en) 1987-11-27
EP0087993A1 (fr) 1983-09-07
DK67783A (da) 1983-08-18
GR77128B (cg-RX-API-DMAC7.html) 1984-09-07
JPS5931707A (ja) 1984-02-20
FR2521565A1 (fr) 1983-08-19
JPH0150449B2 (cg-RX-API-DMAC7.html) 1989-10-30
EP0087993B1 (fr) 1986-07-02
EP0087993B2 (fr) 1990-01-03
FR2521565B1 (fr) 1985-07-05
US4508703A (en) 1985-04-02
ATE20574T1 (de) 1986-07-15
DE87993T1 (de) 1984-02-16
DK67783D0 (da) 1983-02-16
IL67939A0 (en) 1983-06-15
ES8404690A1 (es) 1984-05-01
SG55887G (en) 1987-11-13
CA1208133A (en) 1986-07-22
ES519878A0 (es) 1984-05-01

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