DE3311701A1 - Antimykotische mittel mit hoher wirkstoff-freisetzung in form von creme - Google Patents

Antimykotische mittel mit hoher wirkstoff-freisetzung in form von creme

Info

Publication number
DE3311701A1
DE3311701A1 DE19833311701 DE3311701A DE3311701A1 DE 3311701 A1 DE3311701 A1 DE 3311701A1 DE 19833311701 DE19833311701 DE 19833311701 DE 3311701 A DE3311701 A DE 3311701A DE 3311701 A1 DE3311701 A1 DE 3311701A1
Authority
DE
Germany
Prior art keywords
cream
active substance
bifonazole
high active
substance release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833311701
Other languages
German (de)
English (en)
Inventor
Karlheinz Dr Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE19833311701 priority Critical patent/DE3311701A1/de
Priority to ES530846A priority patent/ES530846A0/es
Priority to PT78313A priority patent/PT78313B/pt
Priority to JP59056374A priority patent/JPS59184106A/ja
Priority to PH30446A priority patent/PH20420A/en
Priority to IL71362A priority patent/IL71362A0/xx
Priority to GR74236A priority patent/GR81485B/el
Priority to CA000450707A priority patent/CA1212327A/en
Priority to LU85271A priority patent/LU85271A1/de
Priority to CH1598/84A priority patent/CH660126A5/de
Priority to ZA842337A priority patent/ZA842337B/xx
Priority to FR8404906A priority patent/FR2543435B1/fr
Priority to SE8401748A priority patent/SE8401748L/xx
Priority to CY135884A priority patent/CY1358A/en
Priority to IT20303/84A priority patent/IT1173761B/it
Priority to GB08408067A priority patent/GB2137091B/en
Priority to BE0/212659A priority patent/BE899278A/fr
Priority to AU26236/84A priority patent/AU564956B2/en
Priority to KR1019840001659A priority patent/KR840008284A/ko
Publication of DE3311701A1 publication Critical patent/DE3311701A1/de
Priority to ES539290A priority patent/ES8601693A1/es
Priority to ES539289A priority patent/ES8601692A1/es
Priority to KE3704A priority patent/KE3704A/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE19833311701 1983-03-30 1983-03-30 Antimykotische mittel mit hoher wirkstoff-freisetzung in form von creme Withdrawn DE3311701A1 (de)

Priority Applications (22)

Application Number Priority Date Filing Date Title
DE19833311701 DE3311701A1 (de) 1983-03-30 1983-03-30 Antimykotische mittel mit hoher wirkstoff-freisetzung in form von creme
ES530846A ES530846A0 (es) 1983-03-30 1984-03-22 Agentes antimicoticos con elevada liberacion del producto activo
PT78313A PT78313B (en) 1983-03-30 1984-03-26 Process for preparing antimycotic agents with a high release of active compund in the form of a cream containing biphonazol
JP59056374A JPS59184106A (ja) 1983-03-30 1984-03-26 抗糸状菌剤
PH30446A PH20420A (en) 1983-03-30 1984-03-27 Antimycotic agent with a high release of active compound,for the form of a cream
IL71362A IL71362A0 (en) 1983-03-30 1984-03-27 Antimycotic agent containing bifonazole with a high release of active compound,in the form of a cream
GR74236A GR81485B (forum.php) 1983-03-30 1984-03-28
CA000450707A CA1212327A (en) 1983-03-30 1984-03-28 Antimycotic agent with a high release of active compound, in the form of a cream
LU85271A LU85271A1 (de) 1983-03-30 1984-03-28 Antimykotisches mittel mit hoher wirkstoff-freisetzung in form von creme
FR8404906A FR2543435B1 (fr) 1983-03-30 1984-03-29 Composition antimycosique sous forme de creme au bifonazole, a forte liberation de substance active
BE0/212659A BE899278A (fr) 1983-03-30 1984-03-29 Agent antimycotique a haute liberation de substance active sous forme d'une creme.
CH1598/84A CH660126A5 (de) 1983-03-30 1984-03-29 Antimykotisches mittel und verfahren zu seiner herstellung.
SE8401748A SE8401748L (sv) 1983-03-30 1984-03-29 Antimykotiskt medel i form av krem med hoggradig frigoring av verksam substans
CY135884A CY1358A (en) 1983-03-30 1984-03-29 Antimycotic agent with a high release of active compounds, in the form of a cream
IT20303/84A IT1173761B (it) 1983-03-30 1984-03-29 Prodotto antimicotico con elevata cessione di sostanza attiva sotto forma di crema
GB08408067A GB2137091B (en) 1983-03-30 1984-03-29 Antimycotic agent with a high release of active compounds, in the form of a cream
ZA842337A ZA842337B (en) 1983-03-30 1984-03-29 Antimycotic agent with a high release of active compound,in the form of a cream
AU26236/84A AU564956B2 (en) 1983-03-30 1984-03-29 Antimycotic agent
KR1019840001659A KR840008284A (ko) 1983-03-30 1984-03-30 바이픈아졸 조성물의 제조방법
ES539290A ES8601693A1 (es) 1983-03-30 1984-12-31 Un procedimiento para la obtencion de preparados del bifonazol con elevada liberacion del producto activo
ES539289A ES8601692A1 (es) 1983-03-30 1984-12-31 Un procedimiento para la obtencion de preparados del bifonazol con elevada liberacion del producto activo
KE3704A KE3704A (en) 1983-03-30 1987-03-09 Antimycotic agent with a high release of active compounds,in the form of a cream

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833311701 DE3311701A1 (de) 1983-03-30 1983-03-30 Antimykotische mittel mit hoher wirkstoff-freisetzung in form von creme

Publications (1)

Publication Number Publication Date
DE3311701A1 true DE3311701A1 (de) 1984-10-04

Family

ID=6195162

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19833311701 Withdrawn DE3311701A1 (de) 1983-03-30 1983-03-30 Antimykotische mittel mit hoher wirkstoff-freisetzung in form von creme

Country Status (19)

Country Link
JP (1) JPS59184106A (forum.php)
KR (1) KR840008284A (forum.php)
AU (1) AU564956B2 (forum.php)
BE (1) BE899278A (forum.php)
CA (1) CA1212327A (forum.php)
CH (1) CH660126A5 (forum.php)
CY (1) CY1358A (forum.php)
DE (1) DE3311701A1 (forum.php)
ES (3) ES530846A0 (forum.php)
FR (1) FR2543435B1 (forum.php)
GB (1) GB2137091B (forum.php)
GR (1) GR81485B (forum.php)
IT (1) IT1173761B (forum.php)
KE (1) KE3704A (forum.php)
LU (1) LU85271A1 (forum.php)
PH (1) PH20420A (forum.php)
PT (1) PT78313B (forum.php)
SE (1) SE8401748L (forum.php)
ZA (1) ZA842337B (forum.php)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5087620A (en) * 1990-05-17 1992-02-11 Bristol-Myers Squibb Co. Controlled dermal penetration enhancement using imidazoles
MX9303406A (es) * 1992-06-08 1994-01-31 Schering Plough Healthcare Composiciones estables anti-fungales de imidazol en polvo.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3045913A1 (de) * 1980-12-05 1982-07-08 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung
DE3045915A1 (de) * 1980-12-05 1982-07-08 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern
DE3045914A1 (de) * 1980-12-05 1982-07-22 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2461406C2 (de) * 1974-12-24 1984-06-14 Bayer Ag, 5090 Leverkusen Azolyl-(1)-methane und deren Salze, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE3106635A1 (de) * 1981-02-23 1982-09-09 Bayer Ag Antimykotisches mittel mit hoher wirkstoff-freisetzung in form von stiften

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3045913A1 (de) * 1980-12-05 1982-07-08 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung
DE3045915A1 (de) * 1980-12-05 1982-07-08 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern
DE3045914A1 (de) * 1980-12-05 1982-07-22 Bayer Ag, 5090 Leverkusen Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern

Also Published As

Publication number Publication date
CA1212327A (en) 1986-10-07
ZA842337B (en) 1984-11-28
GB8408067D0 (en) 1984-05-10
SE8401748D0 (sv) 1984-03-29
IT8420303A0 (it) 1984-03-29
SE8401748L (sv) 1984-10-01
GR81485B (forum.php) 1984-12-11
GB2137091A (en) 1984-10-03
ES8503947A1 (es) 1985-04-16
ES530846A0 (es) 1985-04-16
PT78313B (en) 1986-06-02
FR2543435B1 (fr) 1988-06-17
BE899278A (fr) 1984-10-01
KR840008284A (ko) 1984-12-14
PT78313A (en) 1984-04-01
AU564956B2 (en) 1987-09-03
GB2137091B (en) 1986-10-01
ES539290A0 (es) 1985-11-16
KE3704A (en) 1987-03-27
JPS59184106A (ja) 1984-10-19
AU2623684A (en) 1984-10-04
IT1173761B (it) 1987-06-24
LU85271A1 (de) 1984-11-14
ES8601693A1 (es) 1985-11-16
PH20420A (en) 1987-01-05
CY1358A (en) 1987-08-07
ES539289A0 (es) 1985-11-16
ES8601692A1 (es) 1985-11-16
FR2543435A1 (fr) 1984-10-05
CH660126A5 (de) 1987-03-31

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8110 Request for examination paragraph 44
8130 Withdrawal