DE3249684C2 - Verfahren zur Herstellung eines Verbundstoffs mit Langzeit-Freigabe - Google Patents

Verfahren zur Herstellung eines Verbundstoffs mit Langzeit-Freigabe

Info

Publication number
DE3249684C2
DE3249684C2 DE3249684A DE3249684A DE3249684C2 DE 3249684 C2 DE3249684 C2 DE 3249684C2 DE 3249684 A DE3249684 A DE 3249684A DE 3249684 A DE3249684 A DE 3249684A DE 3249684 C2 DE3249684 C2 DE 3249684C2
Authority
DE
Germany
Prior art keywords
poly
udf54
udf53
physiologically active
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3249684A
Other languages
German (de)
English (en)
Inventor
Masaharu Asano
Isao Takasaki Gunma Kaetsu
Masaru Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Atomic Energy Agency
Original Assignee
Japan Atomic Energy Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1067481A external-priority patent/JPS57126415A/ja
Priority claimed from JP1260681A external-priority patent/JPS57128621A/ja
Priority claimed from JP7956781A external-priority patent/JPS57197210A/ja
Application filed by Japan Atomic Energy Research Institute filed Critical Japan Atomic Energy Research Institute
Application granted granted Critical
Publication of DE3249684C2 publication Critical patent/DE3249684C2/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10Macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/2045Polyamides; Polyaminoacids, e.g. polylysine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2063Proteins, e.g. gelatin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/24Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24628Nonplanar uniform thickness material
    • Y10T428/24653Differential nonplanarity at margin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pest Control & Pesticides (AREA)
  • Polymers & Plastics (AREA)
  • Agronomy & Crop Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE3249684A 1981-01-27 1982-01-25 Verfahren zur Herstellung eines Verbundstoffs mit Langzeit-Freigabe Expired DE3249684C2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1067481A JPS57126415A (en) 1981-01-27 1981-01-27 Preparation of prolonged release type composite
JP1260681A JPS57128621A (en) 1981-01-30 1981-01-30 Preparation of prolonged release type composite
JP7956781A JPS57197210A (en) 1981-05-26 1981-05-26 Method for preparation of slow-releasing composite

Publications (1)

Publication Number Publication Date
DE3249684C2 true DE3249684C2 (de) 1987-01-08

Family

ID=27279047

Family Applications (3)

Application Number Title Priority Date Filing Date
DE3249683A Expired DE3249683C2 (de) 1981-01-27 1982-01-25 Verfahren zur Herstellung eines Verbundstoffs mit Langzeit-Freigabe
DE3249684A Expired DE3249684C2 (de) 1981-01-27 1982-01-25 Verfahren zur Herstellung eines Verbundstoffs mit Langzeit-Freigabe
DE19823202255 Granted DE3202255A1 (de) 1981-01-27 1982-01-25 Verfahren zur herstellung eines verbundstoffs mit langzeit-freigabe

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3249683A Expired DE3249683C2 (de) 1981-01-27 1982-01-25 Verfahren zur Herstellung eines Verbundstoffs mit Langzeit-Freigabe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19823202255 Granted DE3202255A1 (de) 1981-01-27 1982-01-25 Verfahren zur herstellung eines verbundstoffs mit langzeit-freigabe

Country Status (2)

Country Link
US (1) US4483807A (ar)
DE (3) DE3249683C2 (ar)

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US5000803A (en) * 1982-09-30 1991-03-19 General Technology Applications, Inc. Freeze blending of reactive liquids and solids
DE3417022A1 (de) * 1984-05-09 1985-11-14 Karl Prof. Dr.med. 7302 Ostfildern Theurer Traeger- und begleitstoffe fuer biologische wirk- und regulationsfaktoren aus zellen und geweben und deren anwendung
CA1277601C (en) * 1985-12-27 1990-12-11 Shigeji Sato Method for producing sustained release formulation
CA1257199A (en) * 1986-05-20 1989-07-11 Paul Y. Wang Preparation containing bioactive macromolecular substance for multi-months release in vivo
USRE35862E (en) * 1986-08-18 1998-07-28 Emisphere Technologies, Inc. Delivery systems for pharmacological agents encapsulated with proteinoids
NL8720442A (nl) * 1986-08-18 1989-04-03 Clinical Technologies Ass Afgeefsystemen voor farmacologische agentia.
US5271945A (en) * 1988-07-05 1993-12-21 Takeda Chemical Industries, Ltd. Sustained release microcapsule for water soluble drug
JPH02138951A (ja) * 1988-08-30 1990-05-28 Asama Kasei Kk 安定化ビタミン粉末及びその製造方法
DE3921912A1 (de) * 1989-07-04 1991-01-17 Roehm Gmbh Polyasparaginsaeurederivate als ueberzugsmittel fuer arzneiformen und lebensmittel
CH679207A5 (ar) * 1989-07-28 1992-01-15 Debiopharm Sa
US5225205A (en) * 1989-07-28 1993-07-06 Debiopharm S.A. Pharmaceutical composition in the form of microparticles
US5439688A (en) * 1989-07-28 1995-08-08 Debio Recherche Pharmaceutique S.A. Process for preparing a pharmaceutical composition
US5451410A (en) * 1993-04-22 1995-09-19 Emisphere Technologies, Inc. Modified amino acids for encapsulating active agents
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5578323A (en) * 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5443841A (en) * 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5447728A (en) * 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5792451A (en) * 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5811127A (en) * 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5643957A (en) * 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
DE69434418T2 (de) * 1993-04-22 2005-12-22 Emisphere Technologies, Inc. Orale Dareichungsform
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5965121A (en) * 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) * 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
BR9604880A (pt) * 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5820881A (en) * 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US5824345A (en) * 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5667806A (en) * 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
WO1997010197A1 (en) * 1995-09-11 1997-03-20 Emisphere Technologies, Inc. METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
IL126318A (en) 1996-03-29 2004-09-27 Emisphere Tech Inc Compounds and compositions for delivering active agents and some novel carrier compounds
WO1997047288A1 (en) 1996-06-14 1997-12-18 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US5939381A (en) * 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5879681A (en) * 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
DE19739031A1 (de) * 1997-09-05 1999-03-11 Suwelack Nachf Dr Otto Mittel zur peroralen Verabreichung, seine Herstellung und Verwendung
US7220596B2 (en) * 1998-04-15 2007-05-22 Utah State University Real time detection of antigens
US6399317B1 (en) * 1998-04-15 2002-06-04 Utah State University Real time detection of antigens
EP1257592A1 (en) * 1999-03-05 2002-11-20 Innovative Technologies, LLC Use of protein conformation for the protection and release of chemical compounds
US7018654B2 (en) * 1999-03-05 2006-03-28 New River Pharmaceuticals Inc. Pharmaceutical composition containing an active agent in an amino acid copolymer structure
US6716452B1 (en) 2000-08-22 2004-04-06 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US20040014082A1 (en) * 2000-08-11 2004-01-22 Invitrogen Corporation Highly homogeneous molecular markers for electrophoresis
US8394813B2 (en) 2000-11-14 2013-03-12 Shire Llc Active agent delivery systems and methods for protecting and administering active agents
US20060014697A1 (en) 2001-08-22 2006-01-19 Travis Mickle Pharmaceutical compositions for prevention of overdose or abuse
US7169752B2 (en) 2003-09-30 2007-01-30 New River Pharmaceuticals Inc. Compounds and compositions for prevention of overdose of oxycodone
CN103265356B (zh) * 2013-05-02 2015-07-01 青岛冠中生态股份有限公司 一种促进植物根瘤菌结瘤的人工土壤和肥料

Citations (1)

* Cited by examiner, † Cited by third party
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DE2556733B2 (de) * 1975-12-17 1981-05-14 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Verfahren zum Isolieren von Albumin aus Blutplasma

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GB1234802A (en) * 1968-04-19 1971-06-09 British American Tobacco Co Improvements relating to the packing of liquids
US3780195A (en) * 1969-10-22 1973-12-18 Balchem Corp Encapsulation process
DK135268A (ar) * 1973-02-09
JPS5325006B2 (ar) * 1973-08-17 1978-07-24
US4073835A (en) * 1976-01-30 1978-02-14 Toyo Ink Manufacturing Co., Ltd. Method of resin encapsulating electrical parts with UV curing of fire retardant resin
US4230687A (en) * 1978-05-30 1980-10-28 Griffith Laboratories U.S.A., Inc. Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices
CH637014A5 (de) * 1978-09-29 1983-07-15 Sandoz Ag Verfahren zur herstellung von suppositorien.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2556733B2 (de) * 1975-12-17 1981-05-14 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Verfahren zum Isolieren von Albumin aus Blutplasma

Also Published As

Publication number Publication date
DE3202255C2 (ar) 1987-07-09
US4483807A (en) 1984-11-20
DE3249683C2 (de) 1986-03-20
DE3202255A1 (de) 1982-10-21

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