DE3229955A1 - Arzneimittel mit analgetischer wirkung - Google Patents
Arzneimittel mit analgetischer wirkungInfo
- Publication number
- DE3229955A1 DE3229955A1 DE19823229955 DE3229955A DE3229955A1 DE 3229955 A1 DE3229955 A1 DE 3229955A1 DE 19823229955 DE19823229955 DE 19823229955 DE 3229955 A DE3229955 A DE 3229955A DE 3229955 A1 DE3229955 A1 DE 3229955A1
- Authority
- DE
- Germany
- Prior art keywords
- fatty acids
- content
- medicament according
- esters
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000000202 analgesic effect Effects 0.000 title claims description 10
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 hydroxy fatty acids Chemical class 0.000 claims abstract description 10
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 9
- 229930195729 fatty acid Natural products 0.000 claims abstract description 9
- 239000000194 fatty acid Substances 0.000 claims abstract description 9
- 150000002148 esters Chemical class 0.000 claims abstract description 8
- 150000004666 short chain fatty acids Chemical class 0.000 claims abstract description 7
- 235000021391 short chain fatty acids Nutrition 0.000 claims abstract description 7
- 229930194542 Keto Natural products 0.000 claims abstract description 6
- 239000003814 drug Substances 0.000 claims description 15
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 5
- 229940079593 drug Drugs 0.000 claims description 4
- 150000001656 butanoic acid esters Chemical class 0.000 claims description 2
- WDJHALXBUFZDSR-UHFFFAOYSA-N Acetoacetic acid Natural products CC(=O)CC(O)=O WDJHALXBUFZDSR-UHFFFAOYSA-N 0.000 claims 1
- FGDSJTQKTCFIFZ-UHFFFAOYSA-N C(CCC)(=O)O.C(CCC)(=O)O.C(CCC)(=O)O.OCC(O)CO Chemical class C(CCC)(=O)O.C(CCC)(=O)O.C(CCC)(=O)O.OCC(O)CO FGDSJTQKTCFIFZ-UHFFFAOYSA-N 0.000 claims 1
- WOWBFOBYOAGEEA-UHFFFAOYSA-N diafenthiuron Chemical compound CC(C)C1=C(NC(=S)NC(C)(C)C)C(C(C)C)=CC(OC=2C=CC=CC=2)=C1 WOWBFOBYOAGEEA-UHFFFAOYSA-N 0.000 claims 1
- 239000002699 waste material Substances 0.000 claims 1
- 229940035676 analgesics Drugs 0.000 abstract description 9
- 239000000730 antalgic agent Substances 0.000 abstract description 9
- 150000003839 salts Chemical class 0.000 abstract description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- 239000002253 acid Substances 0.000 description 7
- 150000001875 compounds Chemical class 0.000 description 5
- 238000001802 infusion Methods 0.000 description 5
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 4
- 150000007513 acids Chemical class 0.000 description 3
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 2
- 239000000787 lecithin Substances 0.000 description 2
- 229940067606 lecithin Drugs 0.000 description 2
- 235000010445 lecithin Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- QOPBEBWGSGFROG-UHFFFAOYSA-N 2-(1h-indol-2-yl)acetic acid Chemical class C1=CC=C2NC(CC(=O)O)=CC2=C1 QOPBEBWGSGFROG-UHFFFAOYSA-N 0.000 description 1
- WHBMMWSBFZVSSR-UHFFFAOYSA-N 3-hydroxybutyric acid Chemical class CC(O)CC(O)=O WHBMMWSBFZVSSR-UHFFFAOYSA-N 0.000 description 1
- USSIQXCVUWKGNF-UHFFFAOYSA-N 6-(dimethylamino)-4,4-diphenylheptan-3-one Chemical compound C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 USSIQXCVUWKGNF-UHFFFAOYSA-N 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 206010012335 Dependence Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- XADCESSVHJOZHK-UHFFFAOYSA-N Meperidine Chemical compound C=1C=CC=CC=1C1(C(=O)OCC)CCN(C)CC1 XADCESSVHJOZHK-UHFFFAOYSA-N 0.000 description 1
- 206010027476 Metastases Diseases 0.000 description 1
- 206010027452 Metastases to bone Diseases 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 1
- 206010038678 Respiratory depression Diseases 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- WDJHALXBUFZDSR-UHFFFAOYSA-M acetoacetate Chemical compound CC(=O)CC([O-])=O WDJHALXBUFZDSR-UHFFFAOYSA-M 0.000 description 1
- 229940124599 anti-inflammatory drug Drugs 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 229940083761 high-ceiling diuretics pyrazolone derivative Drugs 0.000 description 1
- 239000003978 infusion fluid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229960001797 methadone Drugs 0.000 description 1
- INAXVFBXDYWQFN-XHSDSOJGSA-N morphinan Chemical compound C1C2=CC=CC=C2[C@]23CCCC[C@H]3[C@@H]1NCC2 INAXVFBXDYWQFN-XHSDSOJGSA-N 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 229960000482 pethidine Drugs 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 201000001514 prostate carcinoma Diseases 0.000 description 1
- JEXVQSWXXUJEMA-UHFFFAOYSA-N pyrazol-3-one Chemical class O=C1C=CN=N1 JEXVQSWXXUJEMA-UHFFFAOYSA-N 0.000 description 1
- DNTVKOMHCDKATN-UHFFFAOYSA-N pyrazolidine-3,5-dione Chemical class O=C1CC(=O)NN1 DNTVKOMHCDKATN-UHFFFAOYSA-N 0.000 description 1
- 229940058287 salicylic acid derivative anticestodals Drugs 0.000 description 1
- 150000003872 salicylic acid derivatives Chemical class 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- MFBOGIVSZKQAPD-UHFFFAOYSA-M sodium butyrate Chemical compound [Na+].CCCC([O-])=O MFBOGIVSZKQAPD-UHFFFAOYSA-M 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000012899 standard injection Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823229955 DE3229955A1 (de) | 1982-08-12 | 1982-08-12 | Arzneimittel mit analgetischer wirkung |
| LU84952A LU84952A1 (de) | 1982-08-12 | 1983-08-04 | Arzneimittel mit analgetischer wirkung |
| SE8304331A SE8304331L (sv) | 1982-08-12 | 1983-08-09 | Lekemedel med analgetisk verkan |
| FR8313232A FR2531859A1 (fr) | 1982-08-12 | 1983-08-11 | Produits pharmaceutiques avec action analgesique a base d'acides gras |
| GB08321595A GB2126082A (en) | 1982-08-12 | 1983-08-11 | Pharmaceutical preparations having analgetic and cytostatic activity |
| NL8302830A NL8302830A (nl) | 1982-08-12 | 1983-08-11 | Farmaceutisch preparaat met analgetische werking. |
| BE0/211358A BE897536A (fr) | 1982-08-12 | 1983-08-12 | Medicament a action analgestique |
| AU17953/83A AU1795383A (en) | 1982-08-12 | 1983-08-12 | Pharmaceutical preparations having analgetic and cytostatic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823229955 DE3229955A1 (de) | 1982-08-12 | 1982-08-12 | Arzneimittel mit analgetischer wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3229955A1 true DE3229955A1 (de) | 1984-02-16 |
Family
ID=6170655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19823229955 Withdrawn DE3229955A1 (de) | 1982-08-12 | 1982-08-12 | Arzneimittel mit analgetischer wirkung |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE897536A (OSRAM) |
| DE (1) | DE3229955A1 (OSRAM) |
| FR (1) | FR2531859A1 (OSRAM) |
| LU (1) | LU84952A1 (OSRAM) |
| NL (1) | NL8302830A (OSRAM) |
| SE (1) | SE8304331L (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990002549A1 (en) * | 1988-09-07 | 1990-03-22 | Kabivitrum Ab | Glyceride containing nutrient for human and animals |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0420856D0 (en) * | 2004-09-20 | 2004-10-20 | Ketocytonyx Inc | Cns modulators |
| EP1778615A4 (en) | 2004-07-20 | 2010-01-06 | Btg Int Ltd | OLIGOMERE KETONE COMPOUNDS |
-
1982
- 1982-08-12 DE DE19823229955 patent/DE3229955A1/de not_active Withdrawn
-
1983
- 1983-08-04 LU LU84952A patent/LU84952A1/de unknown
- 1983-08-09 SE SE8304331A patent/SE8304331L/ not_active Application Discontinuation
- 1983-08-11 NL NL8302830A patent/NL8302830A/nl not_active Application Discontinuation
- 1983-08-11 FR FR8313232A patent/FR2531859A1/fr active Granted
- 1983-08-12 BE BE0/211358A patent/BE897536A/fr not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990002549A1 (en) * | 1988-09-07 | 1990-03-22 | Kabivitrum Ab | Glyceride containing nutrient for human and animals |
| EP0366631A1 (en) * | 1988-09-07 | 1990-05-02 | Kabivitrum Ab | Nutrient for humans and animals containing glyceride |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2531859A1 (fr) | 1984-02-24 |
| SE8304331L (sv) | 1984-02-13 |
| BE897536A (fr) | 1983-12-01 |
| LU84952A1 (de) | 1983-12-28 |
| FR2531859B3 (OSRAM) | 1985-03-08 |
| NL8302830A (nl) | 1984-03-01 |
| SE8304331D0 (sv) | 1983-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8139 | Disposal/non-payment of the annual fee |