DE3221448A1 - Verfahren zur herstellung von zur intravenoesen verabreichung geeignetem immunglobulin - Google Patents

Verfahren zur herstellung von zur intravenoesen verabreichung geeignetem immunglobulin

Info

Publication number
DE3221448A1
DE3221448A1 DE19823221448 DE3221448A DE3221448A1 DE 3221448 A1 DE3221448 A1 DE 3221448A1 DE 19823221448 DE19823221448 DE 19823221448 DE 3221448 A DE3221448 A DE 3221448A DE 3221448 A1 DE3221448 A1 DE 3221448A1
Authority
DE
Germany
Prior art keywords
immunoglobulin
dipl
ing
solution
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19823221448
Other languages
German (de)
English (en)
Other versions
DE3221448C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Tokusuke Tokio Kimura
Fumio Hasuda Saitama Kurosu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Fujizoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd, Fujizoki Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE3221448A1 publication Critical patent/DE3221448A1/de
Application granted granted Critical
Publication of DE3221448C2 publication Critical patent/DE3221448C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE19823221448 1981-06-09 1982-06-07 Verfahren zur herstellung von zur intravenoesen verabreichung geeignetem immunglobulin Granted DE3221448A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56087503A JPS57203017A (en) 1981-06-09 1981-06-09 Purifying method of immunoglobulin

Publications (2)

Publication Number Publication Date
DE3221448A1 true DE3221448A1 (de) 1983-03-10
DE3221448C2 DE3221448C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-12-08

Family

ID=13916779

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19823221448 Granted DE3221448A1 (de) 1981-06-09 1982-06-07 Verfahren zur herstellung von zur intravenoesen verabreichung geeignetem immunglobulin

Country Status (4)

Country Link
US (1) US4379086A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS57203017A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3221448A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8304431A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
US5608038A (en) * 1993-12-28 1997-03-04 Immuno Aktiengesellschaft Highly concentrated immunoglobulin preparation and method for its production

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58180433A (ja) * 1982-04-16 1983-10-21 Fujirebio Inc 免疫グロブリンから抗補体作用物質の除去法
US4719290A (en) * 1983-09-02 1988-01-12 Armour Pharmaceutical Corporation Composition of intravenous immune globulin
US4835257A (en) * 1984-07-07 1989-05-30 Armour Pharma Gmbh Process for preparing gamma globulin suitable for intravenous administration using peg and a citrate buffer
DE3483784D1 (de) * 1984-07-07 1991-01-31 Woelm Pharma Gmbh & Co Verfahren zur herstellung von gamma-globulin zur intravenoesen anwendung.
US5166322A (en) * 1989-04-21 1992-11-24 Genetics Institute Cysteine added variants of interleukin-3 and chemical modifications thereof
US5225325A (en) * 1990-03-02 1993-07-06 Ventana Medical Systems, Inc. Immunohistochemical staining method and reagents therefor
US5219578A (en) * 1991-02-25 1993-06-15 Innovet, Inc. Composition and method for immunostimulation in mammals
US5695760A (en) * 1995-04-24 1997-12-09 Boehringer Inglehiem Pharmaceuticals, Inc. Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation
EP2953965A4 (en) 2013-02-06 2016-09-14 Agency Science Tech & Res PROTEIN PURIFICATION PROCESS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL286954A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1962-01-03
DE2234069A1 (de) 1971-07-16 1973-02-08 South African Inventions Verfahren zur herstellung eines gereinigten gamma-globulins
US3763135A (en) * 1971-11-08 1973-10-02 Baxter Laboratories Inc Gamma globulin production from cohn fraction iii using polyethylene glycol
US3808189A (en) * 1973-03-15 1974-04-30 American Cyanamid Co Isolation of gamma globulin preparations enriched in iga and igm using polyethylene glycol
CA1064396A (en) * 1975-02-18 1979-10-16 Myer L. Coval Fractional precipitation of gamma globulin with polyethylene glycol
JPS6016406B2 (ja) * 1976-08-06 1985-04-25 マイヤ−、ル−イス、コ−バル 静脈内に投与可能なガンマ・グロブリンの製造法ならびにそれにより調製したガンマ・グロブリン
US4124576A (en) * 1976-12-03 1978-11-07 Coval M L Method of producing intravenously injectable gamma globulin
US4296027A (en) * 1977-08-31 1981-10-20 The Regents Of The University Of Minnesota Pure intravenous human and animal gamma globulins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS ERMITTELT *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
US5608038A (en) * 1993-12-28 1997-03-04 Immuno Aktiengesellschaft Highly concentrated immunoglobulin preparation and method for its production

Also Published As

Publication number Publication date
ES512919A0 (es) 1983-03-01
ES8304431A1 (es) 1983-03-01
JPS57203017A (en) 1982-12-13
US4379086A (en) 1983-04-05
DE3221448C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-12-08

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: FUJIREBIO K.K., TOKYO, JP

8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: C07K 15/06

D2 Grant after examination
8363 Opposition against the patent
8330 Complete renunciation