ES8304431A1 - "un metodo para preparar una inmunoglobulina adecuada para administracion intravenosa". - Google Patents
"un metodo para preparar una inmunoglobulina adecuada para administracion intravenosa".Info
- Publication number
- ES8304431A1 ES8304431A1 ES512919A ES512919A ES8304431A1 ES 8304431 A1 ES8304431 A1 ES 8304431A1 ES 512919 A ES512919 A ES 512919A ES 512919 A ES512919 A ES 512919A ES 8304431 A1 ES8304431 A1 ES 8304431A1
- Authority
- ES
- Spain
- Prior art keywords
- intravenous administration
- peg
- preparing immunoglobulin
- immunoglobulin suitable
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
- Y10S530/831—Cohn fractions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE INMUNOGLOBULINA, QUE TIENE APLICACIONES FARMACOLOGICAS PARA ADMINISTRACION INTRAVENOSA. CONSISTE EN DISOLVER FRACCION II DE PLASMA DE COHN EN UNA DISOLUCION TAMPON DE FOSFATO DE PH 7,0 A 8,0, EN CONCENTRACION 2-3%, AÑADIR POLIETILENGLICOL DE PESO MOLECULAR 4.000 HASTA CONCENTRACION 3-4%; SEPARAR POR CENTRIFUGACION LOS AGREGADOS DE INMUNOGLOBULINA PRECIPITADOS; AÑADIR POLIETILENGLICOL 4.000 HASTA CONCENTRACION 6-8% A PH 6,5-7,0; Y SEPARAR LA INMUNOGLOBULINA EN FORMA DE PASTA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56087503A JPS57203017A (en) | 1981-06-09 | 1981-06-09 | Purifying method of immunoglobulin |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8304431A1 true ES8304431A1 (es) | 1983-03-01 |
ES512919A0 ES512919A0 (es) | 1983-03-01 |
Family
ID=13916779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES512919A Granted ES512919A0 (es) | 1981-06-09 | 1982-06-08 | "un metodo para preparar una inmunoglobulina adecuada para administracion intravenosa". |
Country Status (4)
Country | Link |
---|---|
US (1) | US4379086A (es) |
JP (1) | JPS57203017A (es) |
DE (1) | DE3221448A1 (es) |
ES (1) | ES512919A0 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58180433A (ja) * | 1982-04-16 | 1983-10-21 | Fujirebio Inc | 免疫グロブリンから抗補体作用物質の除去法 |
US4719290A (en) * | 1983-09-02 | 1988-01-12 | Armour Pharmaceutical Corporation | Composition of intravenous immune globulin |
US4835257A (en) * | 1984-07-07 | 1989-05-30 | Armour Pharma Gmbh | Process for preparing gamma globulin suitable for intravenous administration using peg and a citrate buffer |
DE3483784D1 (de) * | 1984-07-07 | 1991-01-31 | Woelm Pharma Gmbh & Co | Verfahren zur herstellung von gamma-globulin zur intravenoesen anwendung. |
DE3641115A1 (de) * | 1986-12-02 | 1988-06-16 | Lentia Gmbh | Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins |
US5166322A (en) * | 1989-04-21 | 1992-11-24 | Genetics Institute | Cysteine added variants of interleukin-3 and chemical modifications thereof |
US5225325A (en) * | 1990-03-02 | 1993-07-06 | Ventana Medical Systems, Inc. | Immunohistochemical staining method and reagents therefor |
US5219578A (en) * | 1991-02-25 | 1993-06-15 | Innovet, Inc. | Composition and method for immunostimulation in mammals |
DE4344824C1 (de) * | 1993-12-28 | 1995-08-31 | Immuno Ag | Hochkonzentriertes Immunglobulin-Präparat und Verfahren zu seiner Herstellung |
US5695760A (en) * | 1995-04-24 | 1997-12-09 | Boehringer Inglehiem Pharmaceuticals, Inc. | Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation |
US9988419B2 (en) | 2013-02-06 | 2018-06-05 | Agency For Science, Technology And Research | Protein purification methods |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL286954A (es) * | 1962-01-03 | |||
US3763135A (en) * | 1971-11-08 | 1973-10-02 | Baxter Laboratories Inc | Gamma globulin production from cohn fraction iii using polyethylene glycol |
US3808189A (en) * | 1973-03-15 | 1974-04-30 | American Cyanamid Co | Isolation of gamma globulin preparations enriched in iga and igm using polyethylene glycol |
CA1064396A (en) * | 1975-02-18 | 1979-10-16 | Myer L. Coval | Fractional precipitation of gamma globulin with polyethylene glycol |
JPS6016406B2 (ja) * | 1976-08-06 | 1985-04-25 | マイヤ−、ル−イス、コ−バル | 静脈内に投与可能なガンマ・グロブリンの製造法ならびにそれにより調製したガンマ・グロブリン |
US4124576A (en) * | 1976-12-03 | 1978-11-07 | Coval M L | Method of producing intravenously injectable gamma globulin |
US4296027A (en) * | 1977-08-31 | 1981-10-20 | The Regents Of The University Of Minnesota | Pure intravenous human and animal gamma globulins |
-
1981
- 1981-06-09 JP JP56087503A patent/JPS57203017A/ja active Pending
-
1982
- 1982-05-28 US US06/383,050 patent/US4379086A/en not_active Expired - Fee Related
- 1982-06-07 DE DE19823221448 patent/DE3221448A1/de active Granted
- 1982-06-08 ES ES512919A patent/ES512919A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
DE3221448C2 (es) | 1988-12-08 |
US4379086A (en) | 1983-04-05 |
DE3221448A1 (de) | 1983-03-10 |
ES512919A0 (es) | 1983-03-01 |
JPS57203017A (en) | 1982-12-13 |
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