DE3166682D1 - Fat emulsion containing a steroid - Google Patents

Fat emulsion containing a steroid

Info

Publication number
DE3166682D1
DE3166682D1 DE8181301931T DE3166682T DE3166682D1 DE 3166682 D1 DE3166682 D1 DE 3166682D1 DE 8181301931 T DE8181301931 T DE 8181301931T DE 3166682 T DE3166682 T DE 3166682T DE 3166682 D1 DE3166682 D1 DE 3166682D1
Authority
DE
Germany
Prior art keywords
steroid
fat emulsion
soybean oil
emulsion containing
inflammatory activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181301931T
Other languages
English (en)
Inventor
Yutaka Mizushima
Kasumasa Yokoyama
Kiichiro Nabeta
Noboru Yamada
Tadakazu Suyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13270735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3166682(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Application granted granted Critical
Publication of DE3166682D1 publication Critical patent/DE3166682D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE8181301931T 1980-05-15 1981-05-01 Fat emulsion containing a steroid Expired DE3166682D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55064875A JPS609726B2 (ja) 1980-05-15 1980-05-15 ステロイド製剤

Publications (1)

Publication Number Publication Date
DE3166682D1 true DE3166682D1 (en) 1984-11-22

Family

ID=13270735

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181301931T Expired DE3166682D1 (en) 1980-05-15 1981-05-01 Fat emulsion containing a steroid

Country Status (11)

Country Link
US (1) US4340594A (de)
EP (1) EP0041772B2 (de)
JP (1) JPS609726B2 (de)
KR (1) KR850001725B1 (de)
AT (1) ATE9870T1 (de)
CA (1) CA1158982A (de)
DE (1) DE3166682D1 (de)
HK (1) HK60985A (de)
IN (1) IN153855B (de)
SG (1) SG37985G (de)
ZA (1) ZA812940B (de)

Families Citing this family (45)

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JPS56135416A (en) 1980-03-27 1981-10-22 Mitsubishi Chem Ind Ltd Pharmaceutical preparation for skin
JPS58201712A (ja) * 1982-05-18 1983-11-24 Green Cross Corp:The 脂肪乳剤
JPS58222014A (ja) * 1982-06-18 1983-12-23 Taisho Pharmaceut Co Ltd プロスタグランジンｅ↓１脂肪乳剤
JPS59152348A (ja) * 1983-02-19 1984-08-31 Kaken Pharmaceut Co Ltd ビフエニリルプロピオン酸エステル誘導体およびその製造法
SE8206744D0 (sv) * 1982-11-26 1982-11-26 Fluidcarbon International Ab Preparat for kontrollerad avgivning av substanser
JPS59141518A (ja) * 1983-02-03 1984-08-14 Taisho Pharmaceut Co Ltd プロスタグランジン脂肪乳剤
JPS59216820A (ja) * 1983-05-20 1984-12-06 Taisho Pharmaceut Co Ltd プロスタグランジン脂肪乳剤
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
JPS601122A (ja) * 1983-06-20 1985-01-07 Green Cross Corp:The ビフエニリルプロピオン酸誘導体脂肪乳剤
US4551449A (en) * 1983-11-16 1985-11-05 The Regents Of The University Of California Avoidance of the immunosuppressive and antiproliferative effects of lipid emulsions
JPS60258110A (ja) * 1984-06-05 1985-12-20 Daigo Eiyou Kagaku Kk 静脈注射可能なプロゲステロン乳化注射液
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters
SE8600632D0 (sv) * 1986-02-13 1986-02-13 Kabivitrum Ab Novel pharmaceutical composition
JPH0794395B2 (ja) * 1986-06-16 1995-10-11 株式会社ミドリ十字 移植片の拒絶反応抑制剤
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
US5043329A (en) * 1987-02-17 1991-08-27 Board Of Regents, University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US4950656A (en) * 1987-02-17 1990-08-21 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
US5260284A (en) * 1987-02-17 1993-11-09 Board Of Regents, The University Of Texas System Methods employing unique mixtures of polar and neutral lipids and sterol for lung surfactant replacement therapy
DE4338086A1 (de) * 1993-11-08 1995-05-11 Dietl Hans Cyclosporin(e) enthaltende pharmazeutische Zubereitung zur oralen Applikation sowie Verfahren zu ihrer Herstellung
DE4338046A1 (de) * 1993-11-08 1995-05-11 Dietl Hans Fettlösliche Arzneimittel erhaltende flüssige pharmazeutische Zubereitung zur oralen Anwendung
US5670163A (en) * 1994-06-20 1997-09-23 Kv Pharmaceuticals Company Long acting GI and esophageal protectant
US5554379A (en) * 1994-06-20 1996-09-10 Kv Pharmaceutical Company Long acting GI and esophageal protectant
JPH0827018A (ja) * 1994-07-22 1996-01-30 Sanwa Kagaku Kenkyusho Co Ltd 生理活性ペプチド又は蛋白質を含有する薬剤組成物
US5554380A (en) * 1994-08-04 1996-09-10 Kv Pharmaceutical Company Bioadhesive pharmaceutical delivery system
KR100508910B1 (ko) * 1995-10-17 2006-04-20 알티피 파마 코포레이션 불용성약물방출
US5709878A (en) * 1996-08-02 1998-01-20 Rosenbaum; Jerry Transdermal delivery of dehydroepiandrosterone
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
IL121647A (en) * 1997-08-28 2001-07-24 Pharmateam Dev Ltd Pharmaceutical compositions for the treatment of ocular inflammation comprising dexamethasone palmitate
US5885597A (en) * 1997-10-01 1999-03-23 Medical Research Industries,Inc. Topical composition for the relief of pain
US5869090A (en) * 1998-01-20 1999-02-09 Rosenbaum; Jerry Transdermal delivery of dehydroepiandrosterone
CN1289091C (zh) * 1998-02-11 2006-12-13 Rtp药品公司 治疗炎症的药物组合物和相关用途
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
AU764001B2 (en) 1998-05-29 2003-08-07 Skyepharma Canada Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
DE69912441T2 (de) 1998-08-19 2004-08-19 Skyepharma Canada Inc., Verdun Injizierbare wässerige propofoldispersionen
PL201578B1 (pl) 1998-11-20 2009-04-30 Skyepharma Canada Inc Stała terapeutyczna postać dawkowania nierozpuszczalnego lub słabo rozpuszczalnego w wodzie związku
KR100801588B1 (ko) * 1999-09-21 2008-02-05 스키에파마 캐나다 인코포레이티드 생물학적 유효 물질의 표면 변형된 미립자 조성물
US6682761B2 (en) 2000-04-20 2004-01-27 Rtp Pharma, Inc. Water-insoluble drug particle process
DE60137943D1 (de) 2000-08-31 2009-04-23 Jagotec Ag Gemahlene partikel
US8586094B2 (en) 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
PL202778B1 (pl) * 2001-02-22 2009-07-31 Skyepharma Canada Inc Postać dawkowana kombinacji statyny i fenofibratu, sposób jej wytwarzania i zastosowanie
PL1864667T3 (pl) * 2006-06-01 2014-01-31 Santen Sas Zastosowanie proleków do podania do ciała szklistego oka
EP2229174A1 (de) * 2007-12-04 2010-09-22 Novagali Pharma S.A. Zusammensetzungen mit einem kortikosteroid-prodrug wie dexamethasonpalmitat zur behandlung von augenerkrankungen
CN106727308A (zh) * 2016-12-14 2017-05-31 广东药科大学 一种地塞米松脂质乳滴眼液及其制备方法
CN116098866A (zh) * 2022-12-15 2023-05-12 中南大学湘雅医院 一种用于治疗关节痛的糖皮质激素脂肪乳、其制法及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1106455B (de) * 1959-05-29 1961-05-10 Upjohn Co Salbengrundlage
US3452014A (en) * 1964-08-14 1969-06-24 Upjohn Co 2,5-dimethylpyrazine p-toluenesulfonate
JPS4524514Y1 (de) * 1965-10-15 1970-09-26
GB1196074A (en) * 1967-03-01 1970-06-24 Warner Lambert Pharmaceutical 6alpha,9alpha-Difluoroprednisolone 17-Valerate 21-Acetate
JPS5850964B2 (ja) * 1978-03-07 1983-11-14 東興薬品工業株式会社 ステロイド含有クリ−ム製剤およびその製造方法
JPS5930674Y2 (ja) * 1978-05-02 1984-09-01 ヤンマー農機株式会社 脱穀機の揺動選別装置
JPS6030652B2 (ja) * 1979-05-07 1985-07-17 株式会社ミドリ十字 静脈注射用脂肪乳剤

Also Published As

Publication number Publication date
EP0041772A2 (de) 1981-12-16
CA1158982A (en) 1983-12-20
SG37985G (en) 1985-11-15
IN153855B (de) 1984-08-25
JPS56167616A (en) 1981-12-23
JPS609726B2 (ja) 1985-03-12
KR850001725B1 (ko) 1985-12-07
EP0041772B1 (de) 1984-10-17
HK60985A (en) 1985-08-23
US4340594A (en) 1982-07-20
EP0041772A3 (en) 1982-06-30
EP0041772B2 (de) 1990-04-18
ZA812940B (en) 1982-05-26
KR830005851A (ko) 1983-09-14
ATE9870T1 (de) 1984-11-15

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
V448 Application of spc

Free format text: PRODUCT NAME: DEXAMETHASON-21-PALMITAT; REGISTRATION NO/DATE: 8509.00.00, 19900928

Spc suppl protection certif: 193 75 101

Filing date: 19930701

V457 Spc granted

Free format text: PRODUCT NAME: DEXAMETHASON-21-PALMITAT; REGISTRATION NO/DATE: 8509.00.00, 19900928

Spc suppl protection certif: 193 75 101

Filing date: 19930701

8327 Change in the person/name/address of the patent owner

Owner name: YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD., OSAKA,

8327 Change in the person/name/address of the patent owner

Owner name: WELFIDE CORP., OSAKA, JP

V464 Spc expired

Free format text: PRODUCT NAME: DEXAMETHASON-21-PALMITAT; REGISTRATION NO/DATE: 8509.00.00, 19900928

Spc suppl protection certif: 193 75 101

Filing date: 19930701