DE3152175T1 - Platinum(ii)complexes and antineoplastic agents containing same as effective ingredients - Google Patents

Platinum(ii)complexes and antineoplastic agents containing same as effective ingredients

Info

Publication number
DE3152175T1
DE3152175T1 DE813152175T DE3152175T DE3152175T1 DE 3152175 T1 DE3152175 T1 DE 3152175T1 DE 813152175 T DE813152175 T DE 813152175T DE 3152175 T DE3152175 T DE 3152175T DE 3152175 T1 DE3152175 T1 DE 3152175T1
Authority
DE
Germany
Prior art keywords
hcoh
platinum
coo
meaning
complex according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE813152175T
Other languages
German (de)
English (en)
Other versions
DE3152175C2 (enExample
Inventor
Y Kidani
M Noji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Publication of DE3152175T1 publication Critical patent/DE3152175T1/de
Application granted granted Critical
Publication of DE3152175C2 publication Critical patent/DE3152175C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/10—Polyhydroxy carboxylic acids
    • C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE813152175T 1980-07-05 1981-07-04 Platinum(ii)complexes and antineoplastic agents containing same as effective ingredients Granted DE3152175T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9206680A JPS5716895A (en) 1980-07-05 1980-07-05 Platinum 2 complex and antitumor agent containing the same as active principle
PCT/JP1981/000154 WO1982000145A1 (en) 1980-07-05 1981-07-04 Platinum(ii)complexes and antineoplastic agents containing same as effective ingredients

Publications (2)

Publication Number Publication Date
DE3152175T1 true DE3152175T1 (de) 1982-11-18
DE3152175C2 DE3152175C2 (enExample) 1989-11-30

Family

ID=14044093

Family Applications (1)

Application Number Title Priority Date Filing Date
DE813152175T Granted DE3152175T1 (de) 1980-07-05 1981-07-04 Platinum(ii)complexes and antineoplastic agents containing same as effective ingredients

Country Status (5)

Country Link
US (1) US4477387A (enExample)
EP (1) EP0055300A4 (enExample)
JP (1) JPS5716895A (enExample)
DE (1) DE3152175T1 (enExample)
WO (1) WO1982000145A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5921697A (ja) * 1982-06-24 1984-02-03 Yoshinori Kitani 新規な白金錯体
JPS59112995A (ja) * 1982-12-21 1984-06-29 Shionogi & Co Ltd 新規グリコ−ル酸白金錯体
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
DE3405611A1 (de) * 1983-02-18 1984-08-23 Degussa Ag, 6000 Frankfurt (1,2-diphenyl-ethylendiamin)-platin(ii)-komplexverbindungen
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
DE3475782D1 (en) * 1983-06-20 1989-02-02 Research Corp Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
EP0136012B1 (en) * 1983-08-05 1989-04-19 Yoshinori Kidani Cytostatic platinum complexes
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
US4665210A (en) * 1984-12-17 1987-05-12 American Cyanamid Company Platinum complexes of aliphatic tricarboxylic acids
ZA86704B (en) * 1985-02-23 1986-10-29 Asta Werke Ag Chem Fab Tumor retarding(1-benzyl-ethylenediamine9-platin(ii)-complexes
JPS6296A (ja) * 1985-03-06 1987-01-06 Sumitomo Pharmaceut Co Ltd 脂溶性白金（２）錯体
EP0207202A1 (en) * 1985-07-04 1987-01-07 Yoshinori Kidani Anti-tumor platinum complexes
US4567285A (en) * 1985-07-10 1986-01-28 Yoshinori Kidani Complex compounds of platinum
JPS6345290A (ja) * 1985-08-27 1988-02-26 Nippon Kayaku Co Ltd 新規白金錯体
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
US4904809A (en) * 1987-09-25 1990-02-27 Ss Pharmaceutical Co., Ltd. Platinum complex
DE8817132U1 (de) * 1988-01-09 1993-04-22 Asta Medica AG, 6000 Frankfurt 1,2-Bis(aminomethyl)cyclobutan-Platin-Komplexe
US5049686A (en) * 1989-09-13 1991-09-17 Warner-Lambert Company Novel large-ring diamine platinum(II) and platinum(IV) chelates
CZ300664B6 (cs) * 2007-01-22 2009-07-15 Pliva-Lachema A. S. Sterilní kapalná farmaceutická kompozice a zpusob její výroby
CZ300665B6 (cs) * 2007-01-22 2009-07-15 Pliva-Lachema A. S. Sterilní kapalná farmaceutická kompozice a zpusob její výroby
CN105899519B (zh) * 2013-11-11 2021-11-09 协同医药发展有限公司 金属络合物及治疗方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588505A5 (enExample) * 1972-06-08 1977-06-15 Research Corp
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
DE2845371A1 (de) * 1977-10-19 1979-04-26 Johnson Matthey Co Ltd Platinkomplexverbindung, pharmazeutische stoffzusammensetzung mit einer solchen verbindung und deren anwendung
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体
US4271085A (en) * 1979-06-20 1981-06-02 Engelhard Minerals & Chemicals Corporation Cis-platinum (II) amine lactate complexes
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex

Also Published As

Publication number Publication date
EP0055300A1 (en) 1982-07-07
WO1982000145A1 (en) 1982-01-21
JPS5716895A (en) 1982-01-28
EP0055300A4 (en) 1982-10-14
US4477387A (en) 1984-10-16
DE3152175C2 (enExample) 1989-11-30

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: C07C 87/00

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee