DE3131748A1 - Indolverbindungen, verfahren zu ihrer herstellung und diese verindungen enthaltende arzneimittel - Google Patents
Indolverbindungen, verfahren zu ihrer herstellung und diese verindungen enthaltende arzneimittelInfo
- Publication number
- DE3131748A1 DE3131748A1 DE19813131748 DE3131748A DE3131748A1 DE 3131748 A1 DE3131748 A1 DE 3131748A1 DE 19813131748 DE19813131748 DE 19813131748 DE 3131748 A DE3131748 A DE 3131748A DE 3131748 A1 DE3131748 A1 DE 3131748A1
- Authority
- DE
- Germany
- Prior art keywords
- group
- compound
- methyl
- general formula
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8026288 | 1980-08-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3131748A1 true DE3131748A1 (de) | 1982-04-01 |
| DE3131748C2 DE3131748C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-04-23 |
Family
ID=10515412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19813131748 Granted DE3131748A1 (de) | 1980-08-12 | 1981-08-11 | Indolverbindungen, verfahren zu ihrer herstellung und diese verindungen enthaltende arzneimittel |
Country Status (28)
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1170387B (it) * | 1982-06-07 | 1987-06-03 | Glaxo Group Ltd | Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono |
| GB8332435D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8332437D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8332434D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Production of chemical compounds |
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| US4833153A (en) * | 1985-11-08 | 1989-05-23 | Glaxo Group Limited | Indole derivatives |
| GB8530507D0 (en) * | 1985-12-11 | 1986-01-22 | Glaxo Group Plc | Chemical compounds |
| GB8600398D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| US5270333A (en) * | 1986-01-28 | 1993-12-14 | Glaxo Group Limited | Indole derivatives |
| GB8607824D0 (en) * | 1986-03-27 | 1986-04-30 | Glaxo Group Ltd | Chemical compounds |
| DE3613623A1 (de) * | 1986-04-23 | 1987-10-29 | Bayer Ag | N-dihydroindolylethyl-sulfonamide |
| GB8615599D0 (en) * | 1986-06-26 | 1986-07-30 | Glaxo Group Ltd | Chemical compounds |
| US5225431A (en) * | 1987-10-23 | 1993-07-06 | Burroughs Wellcome Co. | Therapeutic substituted indole compounds and compositions thereof |
| GB8819024D0 (en) * | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
| CA2042295A1 (fr) * | 1990-05-15 | 1991-11-16 | Jacques Chauveau | Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant |
| ATE156823T1 (de) * | 1990-06-07 | 1997-08-15 | Zeneca Ltd | Therapeutische heterocyclische verbindungen |
| GB9022250D0 (en) * | 1990-10-12 | 1990-11-28 | Glaxo Group Ltd | Medicaments |
| US5559129A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc | Indole derivatives |
| US5607951A (en) * | 1990-10-15 | 1997-03-04 | Pfizer Inc | Indole derivatives |
| US5559246A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc. | Indole derivatives |
| DE9190141U1 (de) * | 1990-10-15 | 1993-07-15 | Pfizer Inc., New York, N.Y. | Indolderivate |
| US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
| US5578612A (en) * | 1990-10-15 | 1996-11-26 | Pfizer Inc. | Indole derivatives |
| CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
| GB9103770D0 (en) * | 1991-02-22 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| ES2033578B1 (es) * | 1991-06-06 | 1995-01-16 | Quimica Sint S A Con El 50 | Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida. |
| ES2033577B1 (es) * | 1991-06-06 | 1995-01-16 | Quimica Sint S A Con El 50 | Procedimiento para la obtencion de la 2-carboxi-3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida y sus esteres alquilicos inferiores. |
| GB9209882D0 (en) * | 1992-05-07 | 1992-06-24 | Glaxo Lab Sa | Compositions |
| GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
| IL106445A (en) * | 1992-07-30 | 1998-01-04 | Merck Sharp & Dohme | History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them |
| CN1129933A (zh) * | 1993-08-31 | 1996-08-28 | 辉瑞大药厂 | 5-芳基吲哚衍生物 |
| US5468768A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antimigraine derivatives of indolylcycloalkanylamines |
| GB9417310D0 (en) | 1994-08-27 | 1994-10-19 | Pfizer Ltd | Therapeutic agents |
| JPH11513666A (ja) * | 1995-10-10 | 1999-11-24 | イーライ・リリー・アンド・カンパニー | Ｎ−［２−置換−３−（２−アミノエチル）−１ｈ−インドール−５−イル］−アミド：新規５−ｈｔ▲下１ｆ▼作動剤 |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
| US5994352A (en) * | 1998-11-13 | 1999-11-30 | Pfizer Inc. | 5-arylindole derivatives |
| WO2002079153A1 (en) * | 2001-03-28 | 2002-10-10 | Biocatalytics, Inc. | Method for producing tryptamine derivatives |
| DE60236723D1 (de) * | 2001-04-13 | 2010-07-29 | Organo Corp | Elektrodeionizationsvorrichtung für Wasserreinigung |
| DK1883451T3 (da) * | 2005-04-13 | 2011-03-14 | Neuraxon Inc | Substituerede indolforbindelser med NOS-hæmmende virkning |
| WO2017004501A1 (en) | 2015-07-02 | 2017-01-05 | Civitas Therapeutics, Inc. | Triptan powders for pulmonary delivery |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2940687A1 (de) * | 1978-10-12 | 1980-04-30 | Glaxo Group Ltd | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2870162A (en) * | 1954-04-28 | 1959-01-20 | Upjohn Co | Production of certain tryptamines and compounds produced in the process |
| BE632051A (fr) * | 1963-05-08 | 1963-11-18 | Sandoz Sa | Nouveaux dérivés de l'indole et leur préparation. |
| CH442303A (de) * | 1964-06-26 | 1967-08-31 | Sandoz Ag | Verfahren zur Herstellung von neuen Indol-Derivaten |
| US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
| FR2334358A1 (fr) * | 1975-12-12 | 1977-07-08 | Sogeras | Nouveaux medicaments derives de l'indole |
| US4180509A (en) * | 1977-07-01 | 1979-12-25 | Merrell Toraude Et Compagnie | α-Ethynyl tryptophanes |
-
1981
- 1981-08-10 ZW ZW193/81A patent/ZW19381A1/xx unknown
- 1981-08-11 IL IL63541A patent/IL63541A/xx unknown
- 1981-08-11 NZ NZ197997A patent/NZ197997A/en unknown
- 1981-08-11 PH PH26033A patent/PH17428A/en unknown
- 1981-08-11 NL NL8103768A patent/NL8103768A/xx not_active Application Discontinuation
- 1981-08-11 GR GR65766A patent/GR74536B/el unknown
- 1981-08-11 FR FR8115514A patent/FR2488605A1/fr active Granted
- 1981-08-11 IE IE1831/81A patent/IE51492B1/en unknown
- 1981-08-11 NO NO812722A patent/NO812722L/no unknown
- 1981-08-11 DE DE19813131748 patent/DE3131748A1/de active Granted
- 1981-08-11 PT PT73503A patent/PT73503B/pt unknown
- 1981-08-11 GB GB8124480A patent/GB2081717B/en not_active Expired
- 1981-08-11 IT IT49086/81A patent/IT1171451B/it active
- 1981-08-11 AT AT0352881A patent/AT381304B/de not_active IP Right Cessation
- 1981-08-11 ZA ZA815539A patent/ZA815539B/xx unknown
- 1981-08-11 BE BE0/205643A patent/BE889930A/fr not_active IP Right Cessation
- 1981-08-11 SE SE8104782A patent/SE454881B/sv not_active IP Right Cessation
- 1981-08-11 FI FI812475A patent/FI812475A7/fi not_active Application Discontinuation
- 1981-08-11 DK DK357181A patent/DK157680C/da active
- 1981-08-11 ES ES504695A patent/ES504695A0/es active Granted
- 1981-08-11 AU AU73996/81A patent/AU548270B2/en not_active Ceased
- 1981-08-11 LU LU83546A patent/LU83546A1/fr unknown
- 1981-08-11 CH CH5160/81A patent/CH651550A5/fr not_active IP Right Cessation
- 1981-08-12 CA CA000383717A patent/CA1169077A/en not_active Expired
- 1981-08-12 JP JP56125412A patent/JPS5759864A/ja active Granted
- 1981-08-12 CA CA000383718A patent/CA1169429A/en not_active Expired
-
1982
- 1982-07-13 ES ES513935A patent/ES513935A0/es active Granted
- 1982-07-20 AR AR290026A patent/AR231533A1/es active
-
1984
- 1984-06-28 US US06/625,648 patent/US4672067A/en not_active Expired - Fee Related
- 1984-06-29 US US06/626,383 patent/US4636521A/en not_active Expired - Fee Related
-
1986
- 1986-12-30 MY MY577/86A patent/MY8600577A/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2940687A1 (de) * | 1978-10-12 | 1980-04-30 | Glaxo Group Ltd | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Also Published As
Similar Documents
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| US5571833A (en) | Tryptamine analogues, their synthesis and their use as 5-HT1 -like or 5-HT2 receptor agonists | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |