IL63541A - 5-(1-substituted sulfonamidoalkyl)indole-3-alkanamines,their preparation and pharmaceutical compositions containing them - Google Patents

5-(1-substituted sulfonamidoalkyl)indole-3-alkanamines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL63541A
IL63541A IL63541A IL6354181A IL63541A IL 63541 A IL63541 A IL 63541A IL 63541 A IL63541 A IL 63541A IL 6354181 A IL6354181 A IL 6354181A IL 63541 A IL63541 A IL 63541A
Authority
IL
Israel
Prior art keywords
alkanamines
sulfonamidoalkyl
indole
substituted
preparation
Prior art date
Application number
IL63541A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL63541A publication Critical patent/IL63541A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL63541A 1980-08-12 1981-08-11 5-(1-substituted sulfonamidoalkyl)indole-3-alkanamines,their preparation and pharmaceutical compositions containing them IL63541A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8026288 1980-08-12

Publications (1)

Publication Number Publication Date
IL63541A true IL63541A (en) 1985-08-30

Family

ID=10515412

Family Applications (1)

Application Number Title Priority Date Filing Date
IL63541A IL63541A (en) 1980-08-12 1981-08-11 5-(1-substituted sulfonamidoalkyl)indole-3-alkanamines,their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
US (2) US4672067A (xx)
JP (1) JPS5759864A (xx)
AR (1) AR231533A1 (xx)
AT (1) AT381304B (xx)
AU (1) AU548270B2 (xx)
BE (1) BE889930A (xx)
CA (2) CA1169429A (xx)
CH (1) CH651550A5 (xx)
DE (1) DE3131748A1 (xx)
DK (1) DK157680C (xx)
ES (2) ES504695A0 (xx)
FI (1) FI812475L (xx)
FR (1) FR2488605A1 (xx)
GB (1) GB2081717B (xx)
GR (1) GR74536B (xx)
IE (1) IE51492B1 (xx)
IL (1) IL63541A (xx)
IT (1) IT1171451B (xx)
LU (1) LU83546A1 (xx)
MY (1) MY8600577A (xx)
NL (1) NL8103768A (xx)
NO (1) NO812722L (xx)
NZ (1) NZ197997A (xx)
PH (1) PH17428A (xx)
PT (1) PT73503B (xx)
SE (1) SE454881B (xx)
ZA (1) ZA815539B (xx)
ZW (1) ZW19381A1 (xx)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79215B (xx) * 1982-06-07 1984-10-22 Glaxo Group Ltd
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
US4833153A (en) * 1985-11-08 1989-05-23 Glaxo Group Limited Indole derivatives
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
US5270333A (en) * 1986-01-28 1993-12-14 Glaxo Group Limited Indole derivatives
GB8607824D0 (en) * 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
NZ238424A (en) * 1990-06-07 1993-12-23 Wellcome Found 3,5-substituted indole derivatives; medicaments and preparatory processes.
GB9022250D0 (en) * 1990-10-12 1990-11-28 Glaxo Group Ltd Medicaments
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
HUT64326A (en) * 1990-10-15 1993-12-28 Pfizer Process for production indole derivatives and pharmaceutical preparations containing these compounds
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
ES2033577B1 (es) * 1991-06-06 1995-01-16 Quimica Sint S A Con El 50 Procedimiento para la obtencion de la 2-carboxi-3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida y sus esteres alquilicos inferiores.
ES2033578B1 (es) * 1991-06-06 1995-01-16 Quimica Sint S A Con El 50 Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida.
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
AU686654B2 (en) * 1993-08-31 1998-02-12 Pfizer Inc. 5-arylindole derivatives
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
US5942536A (en) * 1995-10-10 1999-08-24 Eli Lilly And Company N- 2-substituted-3-(2-aminoethyl)-1H-indol-5-YL!-Amides: new 5-HT1F agonists
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
WO2002079153A1 (en) * 2001-03-28 2002-10-10 Biocatalytics, Inc. Method for producing tryptamine derivatives
KR20030016291A (ko) * 2001-04-13 2003-02-26 오르가노 가부시키가이샤 이온교환체
US7375219B2 (en) * 2005-04-13 2008-05-20 Neuraxon, Inc. Substituted indole compounds having NOS inhibitory activity
EP3316865A4 (en) 2015-07-02 2019-01-23 Civitas Therapeutics, Inc. POWDERS CONTAINING TRIPTAN, FOR PULMONARY DELIVERY

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870162A (en) * 1954-04-28 1959-01-20 Upjohn Co Production of certain tryptamines and compounds produced in the process
BE632051A (fr) * 1963-05-08 1963-11-18 Sandoz Sa Nouveaux dérivés de l'indole et leur préparation.
CH442303A (de) * 1964-06-26 1967-08-31 Sandoz Ag Verfahren zur Herstellung von neuen Indol-Derivaten
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
US4180509A (en) * 1977-07-01 1979-12-25 Merrell Toraude Et Compagnie α-Ethynyl tryptophanes
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
BE889930A (fr) 1982-02-11
DE3131748A1 (de) 1982-04-01
MY8600577A (en) 1986-12-31
NO812722L (no) 1982-02-15
IE51492B1 (en) 1987-01-07
GB2081717A (en) 1982-02-24
IE811831L (en) 1982-02-12
SE8104782L (sv) 1982-02-13
IT8149086A0 (it) 1981-08-11
AR231533A1 (es) 1984-12-28
ES8404327A1 (es) 1984-04-16
FR2488605B1 (xx) 1984-11-16
NL8103768A (nl) 1982-03-01
ES513935A0 (es) 1984-04-16
DK157680B (da) 1990-02-05
PT73503A (en) 1981-09-01
IT1171451B (it) 1987-06-10
ES8300700A1 (es) 1982-11-01
JPH0148895B2 (xx) 1989-10-20
LU83546A1 (fr) 1983-06-08
GR74536B (xx) 1984-06-29
CA1169077A (en) 1984-06-12
AU548270B2 (en) 1985-12-05
FR2488605A1 (fr) 1982-02-19
ES504695A0 (es) 1982-11-01
PT73503B (en) 1983-09-14
CH651550A5 (fr) 1985-09-30
DK157680C (da) 1990-07-09
NZ197997A (en) 1985-08-16
US4672067A (en) 1987-06-09
US4636521A (en) 1987-01-13
CA1169429A (en) 1984-06-19
ZA815539B (en) 1983-03-30
ATA352881A (de) 1986-02-15
FI812475L (fi) 1982-02-13
AT381304B (de) 1986-09-25
ZW19381A1 (en) 1983-03-09
DE3131748C2 (xx) 1992-04-23
JPS5759864A (en) 1982-04-10
SE454881B (sv) 1988-06-06
PH17428A (en) 1984-08-20
AU7399681A (en) 1982-02-18
GB2081717B (en) 1983-09-28
DK357181A (da) 1982-02-13

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