PT73503B - Process for prparing heterocyclic indol compounds - Google Patents

Process for prparing heterocyclic indol compounds

Info

Publication number
PT73503B
PT73503B PT73503A PT7350381A PT73503B PT 73503 B PT73503 B PT 73503B PT 73503 A PT73503 A PT 73503A PT 7350381 A PT7350381 A PT 7350381A PT 73503 B PT73503 B PT 73503B
Authority
PT
Portugal
Prior art keywords
prparing
heterocyclic
indol compounds
indol
compounds
Prior art date
Application number
PT73503A
Other languages
English (en)
Other versions
PT73503A (en
Inventor
Ian Harold Coates
Keith Mills
Colin Frederick Webb
Michael Dennis Dowle
David Edmund Bays
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PT73503A publication Critical patent/PT73503A/pt
Publication of PT73503B publication Critical patent/PT73503B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT73503A 1980-08-12 1981-08-11 Process for prparing heterocyclic indol compounds PT73503B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8026288 1980-08-12

Publications (2)

Publication Number Publication Date
PT73503A PT73503A (en) 1981-09-01
PT73503B true PT73503B (en) 1983-09-14

Family

ID=10515412

Family Applications (1)

Application Number Title Priority Date Filing Date
PT73503A PT73503B (en) 1980-08-12 1981-08-11 Process for prparing heterocyclic indol compounds

Country Status (28)

Country Link
US (2) US4672067A (pt)
JP (1) JPS5759864A (pt)
AR (1) AR231533A1 (pt)
AT (1) AT381304B (pt)
AU (1) AU548270B2 (pt)
BE (1) BE889930A (pt)
CA (2) CA1169429A (pt)
CH (1) CH651550A5 (pt)
DE (1) DE3131748A1 (pt)
DK (1) DK157680C (pt)
ES (2) ES8300700A1 (pt)
FI (1) FI812475L (pt)
FR (1) FR2488605A1 (pt)
GB (1) GB2081717B (pt)
GR (1) GR74536B (pt)
IE (1) IE51492B1 (pt)
IL (1) IL63541A (pt)
IT (1) IT1171451B (pt)
LU (1) LU83546A1 (pt)
MY (1) MY8600577A (pt)
NL (1) NL8103768A (pt)
NO (1) NO812722L (pt)
NZ (1) NZ197997A (pt)
PH (1) PH17428A (pt)
PT (1) PT73503B (pt)
SE (1) SE454881B (pt)
ZA (1) ZA815539B (pt)
ZW (1) ZW19381A1 (pt)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79215B (pt) * 1982-06-07 1984-10-22 Glaxo Group Ltd
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
EP0225726B1 (en) * 1985-11-08 1991-04-17 Glaxo Group Limited Indole derivatives
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
US5270333A (en) * 1986-01-28 1993-12-14 Glaxo Group Limited Indole derivatives
GB8607824D0 (en) * 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide
GB8615599D0 (en) * 1986-06-26 1986-07-30 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
IL98392A (en) * 1990-06-07 1996-01-19 Wellcome Found History of indole, their preparation and the pharmaceutical preparations containing them
GB9022250D0 (en) * 1990-10-12 1990-11-28 Glaxo Group Ltd Medicaments
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
RU2095360C1 (ru) * 1990-10-15 1997-11-10 Пфайзер Инк. Производные индола, их оптические изомеры и фармацевтически приемлемые соли
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
ES2033578B1 (es) * 1991-06-06 1995-01-16 Quimica Sint S A Con El 50 Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida.
ES2033577B1 (es) * 1991-06-06 1995-01-16 Quimica Sint S A Con El 50 Procedimiento para la obtencion de la 2-carboxi-3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida y sus esteres alquilicos inferiores.
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
KR100191973B1 (ko) * 1993-08-31 1999-06-15 디. 제이. 우드, 스피겔 알렌 제이 5-아릴인돌 유도체
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
AU7261196A (en) * 1995-10-10 1997-04-30 Eli Lilly And Company N-{2-substituted-3-(2-aminoethyl)-1h-indol-5-yl}-amides: new 5-ht1f agonists
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
US20030096379A1 (en) * 2001-03-28 2003-05-22 Kilgore James L. Method for producing tryptamine derivatives
DE60236723D1 (de) * 2001-04-13 2010-07-29 Organo Corp Elektrodeionizationsvorrichtung für Wasserreinigung
PL1883451T3 (pl) * 2005-04-13 2011-05-31 Neuraxon Inc Podstawione związki indolowe mające aktywność hamowania NOS
JP2018524346A (ja) 2015-07-02 2018-08-30 サイヴィタス セラピューティックス，インコーポレイテッド 肺送達のためのトリプタン粉末

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870162A (en) * 1954-04-28 1959-01-20 Upjohn Co Production of certain tryptamines and compounds produced in the process
BE632051A (fr) * 1963-05-08 1963-11-18 Sandoz Sa Nouveaux dérivés de l'indole et leur préparation.
CH442303A (de) * 1964-06-26 1967-08-31 Sandoz Ag Verfahren zur Herstellung von neuen Indol-Derivaten
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
US4180509A (en) * 1977-07-01 1979-12-25 Merrell Toraude Et Compagnie α-Ethynyl tryptophanes
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
NO812722L (no) 1982-02-15
NZ197997A (en) 1985-08-16
US4672067A (en) 1987-06-09
IT8149086A0 (it) 1981-08-11
GR74536B (pt) 1984-06-29
CA1169077A (en) 1984-06-12
AT381304B (de) 1986-09-25
DK157680C (da) 1990-07-09
IL63541A (en) 1985-08-30
MY8600577A (en) 1986-12-31
AU548270B2 (en) 1985-12-05
ATA352881A (de) 1986-02-15
JPS5759864A (en) 1982-04-10
ES504695A0 (es) 1982-11-01
DE3131748C2 (pt) 1992-04-23
IT1171451B (it) 1987-06-10
IE811831L (en) 1982-02-12
GB2081717B (en) 1983-09-28
PT73503A (en) 1981-09-01
FR2488605B1 (pt) 1984-11-16
JPH0148895B2 (pt) 1989-10-20
ES8404327A1 (es) 1984-04-16
NL8103768A (nl) 1982-03-01
US4636521A (en) 1987-01-13
AU7399681A (en) 1982-02-18
DE3131748A1 (de) 1982-04-01
IE51492B1 (en) 1987-01-07
ES8300700A1 (es) 1982-11-01
SE454881B (sv) 1988-06-06
CH651550A5 (fr) 1985-09-30
SE8104782L (sv) 1982-02-13
LU83546A1 (fr) 1983-06-08
ZA815539B (en) 1983-03-30
PH17428A (en) 1984-08-20
FR2488605A1 (fr) 1982-02-19
GB2081717A (en) 1982-02-24
DK357181A (da) 1982-02-13
BE889930A (fr) 1982-02-11
CA1169429A (en) 1984-06-19
ES513935A0 (es) 1984-04-16
AR231533A1 (es) 1984-12-28
DK157680B (da) 1990-02-05
ZW19381A1 (en) 1983-03-09
FI812475L (fi) 1982-02-13

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