DE3128411A1 - Kulturstamm-mutante von esccherichia coli sowie verfahren zur herstellung von phenylalanin - Google Patents

Kulturstamm-mutante von esccherichia coli sowie verfahren zur herstellung von phenylalanin

Info

Publication number
DE3128411A1
DE3128411A1 DE19813128411 DE3128411A DE3128411A1 DE 3128411 A1 DE3128411 A1 DE 3128411A1 DE 19813128411 DE19813128411 DE 19813128411 DE 3128411 A DE3128411 A DE 3128411A DE 3128411 A1 DE3128411 A1 DE 3128411A1
Authority
DE
Germany
Prior art keywords
microorganism
phenylalanine
enzyme
culture
formation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19813128411
Other languages
German (de)
English (en)
Inventor
David Edward Maroubra New South Wales Tribe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Austgen Biojet International Pty Ltd
Original Assignee
Unisearch Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unisearch Ltd filed Critical Unisearch Ltd
Publication of DE3128411A1 publication Critical patent/DE3128411A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222—Phenylalanine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19813128411 1980-07-18 1981-07-17 Kulturstamm-mutante von esccherichia coli sowie verfahren zur herstellung von phenylalanin Ceased DE3128411A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU459080 1980-07-18

Publications (1)

Publication Number Publication Date
DE3128411A1 true DE3128411A1 (de) 1983-09-15

Family

ID=3695035

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813128411 Ceased DE3128411A1 (de) 1980-07-18 1981-07-17 Kulturstamm-mutante von esccherichia coli sowie verfahren zur herstellung von phenylalanin

Country Status (4)

Country Link
US (1) US4681852A (enExample)
JP (1) JPS57170184A (enExample)
DE (1) DE3128411A1 (enExample)
FR (1) FR2486961A1 (enExample)

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EP0140606A1 (en) * 1983-10-07 1985-05-08 Biotechnica International, Inc. Cells and their use in methods for producing product compounds
EP0145156A1 (en) * 1983-10-07 1985-06-19 Biotechnica International, Inc. Expression vectors, host cells comprising such vectors and methods of making desired compounds using such cells

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US5169768A (en) * 1983-10-07 1992-12-08 Biotechnica International, Inc. Method of biosynthesis of phenylalanine
GB8333797D0 (en) * 1983-12-19 1984-01-25 Searle & Co Starch utilization
JPS6178378A (ja) * 1984-09-27 1986-04-21 Ajinomoto Co Inc 芳香族アミノ酸生合成遺伝子を含有する組換えｄｎａ及びそれを有するコリネ型細菌
JPS61247392A (ja) * 1985-02-04 1986-11-04 エンジニツクス　インコ−ポレ−テツド ２種またはより多くのアミノ酸を同時に産生できる組換え微生物
WO1987000202A1 (en) 1985-06-24 1987-01-15 The Nutrasweet Company Composite plasmids for amino acid synthesis
US4753883A (en) * 1986-05-07 1988-06-28 Biotechnica International, Inc. Enzyme deregulation
KR890003714B1 (ko) * 1987-03-26 1989-09-30 주식회사 미원 유전자 조작 미생물에 의한 l-페닐알라닌 제조방법
KR890003682B1 (ko) * 1987-03-26 1989-09-30 주식회사 미원 유전자조작 미생물에 의한 l-페닐알라닌의 제조방법
US5100775A (en) * 1988-03-16 1992-03-31 Smyczek Peter J Method for conducting nucleic acid hybridization in chamber with precise fluid delivery
US5019509A (en) * 1988-04-20 1991-05-28 Genetics Institute, Inc. Method and compositions for the production of l-alanine and derivatives thereof
US5543052A (en) * 1988-07-28 1996-08-06 Alliedsignal Inc. Process for removal of organic pollutants from waste water
US5580770A (en) * 1989-11-02 1996-12-03 Alliedsignal Inc. Support containing particulate adsorbent and microorganisms for removal of pollutants
US4957686A (en) * 1990-02-06 1990-09-18 Norris Alan H Use of bacteriophages to inhibit dental caries
DE69124939T2 (de) * 1990-11-30 1997-10-02 Ajinomoto Kk Rekombinante DNS-Sequenzen kodierend für Enzyme frei von Feedback Inhibition, Plasmide diese Sequenzen enthaltend, transformierte Mikroorganismen nützlich für Produktion von aromatischen Aminosäuren, und deren Verfahren zur Herstellung durch Fermentation
US5168056A (en) * 1991-02-08 1992-12-01 Purdue Research Foundation Enhanced production of common aromatic pathway compounds
WO1993004181A1 (fr) * 1991-08-26 1993-03-04 Kyowa Hakko Kogyo Co., Ltd. Procede pour la production de 4-hydroxy-l-proline
US5409830A (en) * 1992-12-16 1995-04-25 Miwon Co. Ltd. Method for production of l-phenylalanine by Echerichia coli mutant that is resistant to osmotic pressure
US5776736A (en) * 1992-12-21 1998-07-07 Purdue Research Foundation Deblocking the common pathway of aromatic amino acid synthesis
CA2148482C (en) * 1992-12-21 2006-10-31 John W. Frost Deblocking the common pathway of aromatic amino acid synthesis
US5395527A (en) * 1993-07-01 1995-03-07 Eco Equipement Fep Inc. Process and apparatus for treating wastewater in a dynamic, bio sequenced manner
US5629181A (en) * 1993-09-16 1997-05-13 Purdue Research Foundation Synthesis of catechol from biomass-derived carbon sources
US5487987A (en) * 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5487986A (en) * 1994-03-10 1996-01-30 Genzyme Corporation Method for increasing plasmid yield
US5614392A (en) * 1995-06-01 1997-03-25 Food Industry Research And Development Institute Process of L-phenylalanine fermentation
US6274369B1 (en) 1996-02-02 2001-08-14 Invitrogen Corporation Method capable of increasing competency of bacterial cell transformation
WO1997036613A1 (en) 1996-03-29 1997-10-09 Life Technologies, Inc. Method for increasing viability and transformation efficiency of bacteria during storage at low temperatures
AUPO258196A0 (en) * 1996-09-27 1996-10-17 Australian National University, The Method for determining ion channel activity of a substance
DE69829976T2 (de) 1997-02-12 2006-04-27 Invitrogen Corp., Carlsbad Verfahren zur herstellung von zellen
US6210937B1 (en) 1997-04-22 2001-04-03 Bechtel Bwxt Idaho, Llc Development of genetically engineered bacteria for production of selected aromatic compounds
US6030819A (en) * 1998-09-28 2000-02-29 General Electric Company Genetically engineered microorganisms and method for producing 4-hydroxybenzoic acid
ATE335087T1 (de) * 1999-05-28 2006-08-15 Univ North Texas Globaler regulator, verwendet zur erhöhung der synthese von aromatischen substanzen
RU2202607C2 (ru) * 2000-03-03 2003-04-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Штамм бактерий methylophilus methylotrophus - продуцент l-фенилаланина (варианты), способ получения l-фенилаланина
US20030091971A1 (en) * 2001-09-14 2003-05-15 Invitrogen Corporation Composition for stabilizing biological materials
KR100608085B1 (ko) * 2004-02-05 2006-08-02 씨제이 주식회사 ｔｙｒＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한Ｌ-쓰레오닌의 제조방법
JP4665613B2 (ja) * 2004-06-15 2011-04-06 味の素株式会社 Ｌ−チロシン生産菌及びｌ−チロシンの製造法
US7482140B2 (en) * 2004-06-15 2009-01-27 Ajinomoto Co., Inc. L-tyrosine-producing bacterium and a method for producing L-tyrosine
US20060035310A1 (en) * 2004-08-13 2006-02-16 Millipore Corporation Media for recovery of microorganism in the presence of antibiotics
WO2006124895A2 (en) * 2005-05-16 2006-11-23 Massachusetts Institute Of Technology Mutations for enhanced tyrosine production
US7582474B2 (en) * 2005-07-11 2009-09-01 Honeywell International Inc. Process reactor with layered packed bed
EP1764415A1 (en) * 2005-09-20 2007-03-21 Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO Microbial production of p-hydroxybenzyl alcohol
US7700328B2 (en) 2006-06-07 2010-04-20 E.I. Du Pont De Nemours And Company Method for producing an L-tyrosine over-producing bacterial strain
RU2006129690A (ru) 2006-08-16 2008-02-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ
US20080102499A1 (en) * 2006-10-27 2008-05-01 Lori Jean Templeton Method of enhancing L-tyrosine production in recombinant bacteria
CN103403157B (zh) 2011-01-31 2015-08-05 旭化成化学株式会社 苯丙酮酸还原酶及使用该酶制造光学活性苯基乳酸及4-羟基苯基乳酸的制造方法
US9150884B2 (en) 2011-03-08 2015-10-06 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Microbial conversion of glucose to styrene and its derivatives
CA2862051A1 (en) 2012-01-30 2013-08-08 Myriant Corporation Production of muconic acid from genetically engineered microorganisms
US10174346B2 (en) 2013-08-27 2019-01-08 Arizona Board Of Regents On Behalf Of Arizona State University Microorganisms engineered to produce phenol and its derivatives
BR122023023156A2 (pt) * 2015-05-27 2024-03-05 Lanzatech Nz, Inc. Bactéria geneticamente modificada fixadora de c1 capaz de produzir pelo menos um produto derivado de corismato, e, método de fabricação de um produto de fermentação
CN109415684B (zh) 2016-03-02 2022-06-07 Ptt全球化学公众有限公司 从基因工程微生物改进的黏康酸生产
CN110494560A (zh) 2017-02-06 2019-11-22 齐默尔根公司 通过发酵产生酪胺的经改造的生物合成途径
WO2019018302A1 (en) 2017-07-18 2019-01-24 Arizona Board Of Regents On Behalf Of Arizona State University SYNTHETIC METABOLIC FUNNEL PASSAGE FOR BIOCHEMICAL PRODUCTION
WO2019023019A1 (en) 2017-07-25 2019-01-31 Arizona Board Of Regents On Behalf Of Arizona State University MICROBIAL PRODUCTION OF 2-PHENYL ETHANOL FROM RENEWABLE SUBSTRATES
WO2019194279A1 (en) * 2018-04-06 2019-10-10 Ajinomoto Co., Inc. AGRICULTURAL OR HORTICULTURAL COMPOSITION CONTAINING CULTURE BROTH OF Bacillus BACTERIUM
CN112080452B (zh) * 2020-08-17 2023-04-28 天津科技大学 一种高产苯乳酸地衣芽孢杆菌基因工程菌、生产苯乳酸的方法和应用

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US2973304A (en) * 1958-10-02 1961-02-28 Pfizer & Co C Fermentation process
US3700558A (en) * 1967-11-20 1972-10-24 Lepetit Spa Production of l-tryptophan by fermentation
US3660235A (en) * 1969-08-22 1972-05-02 Ajinomoto Kk Method for producing phenylalanine by fermentation
SU875663A1 (ru) * 1978-06-30 1982-09-15 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штаммы е.coLI ВНИИГенетика VL 334 @ N6 и ВНИИГенетика VL 334 @ N7-продуценты L-треонина и способ их получени
FR2440957A1 (fr) * 1978-11-13 1980-06-06 Pasteur Institut Vecteurs appropries a l'insertion dans leurs genomes de fragments d'adn etrangers, selon l'une quelconque des phases de traduction possibles, et moyens pour leur fabrication
JPS5573868A (en) * 1978-11-22 1980-06-03 Mitsubishi Electric Corp Coating method for thin aluminum-silicon alloy film
JPS561890A (en) * 1979-06-15 1981-01-10 Ajinomoto Co Inc Preparation of l-phenylalanine by fermentation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0140606A1 (en) * 1983-10-07 1985-05-08 Biotechnica International, Inc. Cells and their use in methods for producing product compounds
EP0145156A1 (en) * 1983-10-07 1985-06-19 Biotechnica International, Inc. Expression vectors, host cells comprising such vectors and methods of making desired compounds using such cells

Also Published As

Publication number Publication date
FR2486961B1 (enExample) 1985-04-12
FR2486961A1 (fr) 1982-01-22
US4681852A (en) 1987-07-21
JPS57170184A (en) 1982-10-20

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: AUSTGEN-BIOJET INTERNATIONAL PTY., LTD., MELBOURNE

8128 New person/name/address of the agent

Representative=s name: BOEHMERT, A., DIPL.-ING., PAT.-ANW. STAHLBERG, W.,

8110 Request for examination paragraph 44
8131 Rejection