JPS57170184A - Mutant of e. coli and production of phenylalanine - Google Patents
Mutant of e. coli and production of phenylalanineInfo
- Publication number
- JPS57170184A JPS57170184A JP56112061A JP11206181A JPS57170184A JP S57170184 A JPS57170184 A JP S57170184A JP 56112061 A JP56112061 A JP 56112061A JP 11206181 A JP11206181 A JP 11206181A JP S57170184 A JPS57170184 A JP S57170184A
- Authority
- JP
- Japan
- Prior art keywords
- phenylalanine
- mutant
- coli
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000588724 Escherichia coli Species 0.000 title 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 title 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/222—Phenylalanine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
Landscapes
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU459080 | 1980-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57170184A true JPS57170184A (en) | 1982-10-20 |
Family
ID=3695035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56112061A Pending JPS57170184A (en) | 1980-07-18 | 1981-07-17 | Mutant of e. coli and production of phenylalanine |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4681852A (enExample) |
| JP (1) | JPS57170184A (enExample) |
| DE (1) | DE3128411A1 (enExample) |
| FR (1) | FR2486961A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61247392A (ja) * | 1985-02-04 | 1986-11-04 | エンジニツクス インコ−ポレ−テツド | 2種またはより多くのアミノ酸を同時に産生できる組換え微生物 |
| JP2018522536A (ja) * | 2015-05-27 | 2018-08-16 | ランザテク・ニュージーランド・リミテッド | コリスミ酸誘導産物生成のための遺伝子組換え微生物(関連出願の相互参照) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1236412A (en) * | 1983-10-07 | 1988-05-10 | Keith C. Backman | Cell lines and methods for fermentation |
| US4839286A (en) * | 1983-10-07 | 1989-06-13 | Biotechnica International, Inc. | Method of biosynthesis and cells therefor |
| US5169768A (en) * | 1983-10-07 | 1992-12-08 | Biotechnica International, Inc. | Method of biosynthesis of phenylalanine |
| GB8333797D0 (en) * | 1983-12-19 | 1984-01-25 | Searle & Co | Starch utilization |
| JPS6178378A (ja) * | 1984-09-27 | 1986-04-21 | Ajinomoto Co Inc | 芳香族アミノ酸生合成遺伝子を含有する組換えdna及びそれを有するコリネ型細菌 |
| JPS63500215A (ja) * | 1985-06-24 | 1988-01-28 | ザ ヌトラスウイ−ト カンパニ− | アミノ酸合成用の複合プラスミド |
| US4753883A (en) * | 1986-05-07 | 1988-06-28 | Biotechnica International, Inc. | Enzyme deregulation |
| KR890003714B1 (ko) * | 1987-03-26 | 1989-09-30 | 주식회사 미원 | 유전자 조작 미생물에 의한 l-페닐알라닌 제조방법 |
| KR890003682B1 (ko) * | 1987-03-26 | 1989-09-30 | 주식회사 미원 | 유전자조작 미생물에 의한 l-페닐알라닌의 제조방법 |
| US5100775A (en) * | 1988-03-16 | 1992-03-31 | Smyczek Peter J | Method for conducting nucleic acid hybridization in chamber with precise fluid delivery |
| US5019509A (en) * | 1988-04-20 | 1991-05-28 | Genetics Institute, Inc. | Method and compositions for the production of l-alanine and derivatives thereof |
| US5543052A (en) * | 1988-07-28 | 1996-08-06 | Alliedsignal Inc. | Process for removal of organic pollutants from waste water |
| US5580770A (en) * | 1989-11-02 | 1996-12-03 | Alliedsignal Inc. | Support containing particulate adsorbent and microorganisms for removal of pollutants |
| US4957686A (en) * | 1990-02-06 | 1990-09-18 | Norris Alan H | Use of bacteriophages to inhibit dental caries |
| EP0488424B1 (en) * | 1990-11-30 | 1997-03-05 | Ajinomoto Co., Inc. | Recombinant DNA sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant DNA sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation |
| US5168056A (en) * | 1991-02-08 | 1992-12-01 | Purdue Research Foundation | Enhanced production of common aromatic pathway compounds |
| DE69126141T2 (de) * | 1991-08-26 | 1997-08-28 | Kyowa Hakko Kogyo Kk | Verfahren zur herstellung von 4-hydroxy-l-prolin |
| US5409830A (en) * | 1992-12-16 | 1995-04-25 | Miwon Co. Ltd. | Method for production of l-phenylalanine by Echerichia coli mutant that is resistant to osmotic pressure |
| US5776736A (en) * | 1992-12-21 | 1998-07-07 | Purdue Research Foundation | Deblocking the common pathway of aromatic amino acid synthesis |
| KR950704500A (ko) * | 1992-12-21 | 1995-11-20 | 윌리암 디. 그리그스 | 방향족 아미노산 합성의 경로의 탈차단방법(deblocking the common pathway of aromatic amino acid synthesis) |
| US5395527A (en) * | 1993-07-01 | 1995-03-07 | Eco Equipement Fep Inc. | Process and apparatus for treating wastewater in a dynamic, bio sequenced manner |
| US5629181A (en) * | 1993-09-16 | 1997-05-13 | Purdue Research Foundation | Synthesis of catechol from biomass-derived carbon sources |
| US5487987A (en) * | 1993-09-16 | 1996-01-30 | Purdue Research Foundation | Synthesis of adipic acid from biomass-derived carbon sources |
| US5487986A (en) * | 1994-03-10 | 1996-01-30 | Genzyme Corporation | Method for increasing plasmid yield |
| US5614392A (en) * | 1995-06-01 | 1997-03-25 | Food Industry Research And Development Institute | Process of L-phenylalanine fermentation |
| US6274369B1 (en) | 1996-02-02 | 2001-08-14 | Invitrogen Corporation | Method capable of increasing competency of bacterial cell transformation |
| WO1997036613A1 (en) | 1996-03-29 | 1997-10-09 | Life Technologies, Inc. | Method for increasing viability and transformation efficiency of bacteria during storage at low temperatures |
| AUPO258196A0 (en) * | 1996-09-27 | 1996-10-17 | Australian National University, The | Method for determining ion channel activity of a substance |
| EP1005529B1 (en) | 1997-02-12 | 2005-04-27 | Invitrogen Corporation | Methods for lyophilizing competent cells |
| US6210937B1 (en) | 1997-04-22 | 2001-04-03 | Bechtel Bwxt Idaho, Llc | Development of genetically engineered bacteria for production of selected aromatic compounds |
| US6030819A (en) * | 1998-09-28 | 2000-02-29 | General Electric Company | Genetically engineered microorganisms and method for producing 4-hydroxybenzoic acid |
| WO2000073484A1 (en) * | 1999-05-28 | 2000-12-07 | University Of North Texas Health Science Center At Fort Worth | A global regulator used to enhance the synthesis of aromatic substances |
| RU2202607C2 (ru) * | 2000-03-03 | 2003-04-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм бактерий methylophilus methylotrophus - продуцент l-фенилаланина (варианты), способ получения l-фенилаланина |
| US20030091971A1 (en) * | 2001-09-14 | 2003-05-15 | Invitrogen Corporation | Composition for stabilizing biological materials |
| KR100608085B1 (ko) * | 2004-02-05 | 2006-08-02 | 씨제이 주식회사 | tyrR 유전자가 불활성화된 L-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한L-쓰레오닌의 제조방법 |
| JP4665613B2 (ja) * | 2004-06-15 | 2011-04-06 | 味の素株式会社 | L−チロシン生産菌及びl−チロシンの製造法 |
| US7482140B2 (en) | 2004-06-15 | 2009-01-27 | Ajinomoto Co., Inc. | L-tyrosine-producing bacterium and a method for producing L-tyrosine |
| US20060035310A1 (en) * | 2004-08-13 | 2006-02-16 | Millipore Corporation | Media for recovery of microorganism in the presence of antibiotics |
| US7531345B2 (en) * | 2005-05-16 | 2009-05-12 | Massachusetts Institute Of Technology | Mutations for enhanced tyrosine production |
| US7582474B2 (en) * | 2005-07-11 | 2009-09-01 | Honeywell International Inc. | Process reactor with layered packed bed |
| EP1764415A1 (en) * | 2005-09-20 | 2007-03-21 | Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO | Microbial production of p-hydroxybenzyl alcohol |
| US7700328B2 (en) * | 2006-06-07 | 2010-04-20 | E.I. Du Pont De Nemours And Company | Method for producing an L-tyrosine over-producing bacterial strain |
| RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
| US20080102499A1 (en) * | 2006-10-27 | 2008-05-01 | Lori Jean Templeton | Method of enhancing L-tyrosine production in recombinant bacteria |
| JP5714033B2 (ja) | 2011-01-31 | 2015-05-07 | 旭化成ケミカルズ株式会社 | フェニルピルビン酸還元酵素並びに本酵素を用いた光学活性フェニル乳酸及び4−ヒドロキシ−フェニル乳酸の製造方法 |
| WO2012122333A1 (en) | 2011-03-08 | 2012-09-13 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Microbial conversion of glucose to styrene and its derivatives |
| US20150044755A1 (en) | 2012-01-30 | 2015-02-12 | Myriant Corporation | Production of muconic acid from genetically engineered microorganisms |
| US10174346B2 (en) | 2013-08-27 | 2019-01-08 | Arizona Board Of Regents On Behalf Of Arizona State University | Microorganisms engineered to produce phenol and its derivatives |
| SG10202008244TA (en) | 2016-03-02 | 2020-10-29 | Ptt Global Chemical Public Co Ltd | Improved muconic acid production from genetically engineered microorganisms |
| CN110494560A (zh) | 2017-02-06 | 2019-11-22 | 齐默尔根公司 | 通过发酵产生酪胺的经改造的生物合成途径 |
| US11708590B2 (en) | 2017-07-18 | 2023-07-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Synthetic metabolic funneling for biochemical production |
| US11613768B2 (en) | 2017-07-25 | 2023-03-28 | Arizona Board Of Regents On Behalf Of Arizona State University | Microbial production of 2-phenylethanol from renewable substrates |
| EP3775158A1 (en) | 2018-04-06 | 2021-02-17 | Ajinomoto Co., Inc. | Agricultural or horticultural composition containing culture broth of bacillus bacterium |
| CN112080452B (zh) * | 2020-08-17 | 2023-04-28 | 天津科技大学 | 一种高产苯乳酸地衣芽孢杆菌基因工程菌、生产苯乳酸的方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2973304A (en) * | 1958-10-02 | 1961-02-28 | Pfizer & Co C | Fermentation process |
| US3700558A (en) * | 1967-11-20 | 1972-10-24 | Lepetit Spa | Production of l-tryptophan by fermentation |
| US3660235A (en) * | 1969-08-22 | 1972-05-02 | Ajinomoto Kk | Method for producing phenylalanine by fermentation |
| SU875663A1 (ru) * | 1978-06-30 | 1982-09-15 | Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Штаммы е.coLI ВНИИГенетика VL 334 @ N6 и ВНИИГенетика VL 334 @ N7-продуценты L-треонина и способ их получени |
| FR2440957A1 (fr) * | 1978-11-13 | 1980-06-06 | Pasteur Institut | Vecteurs appropries a l'insertion dans leurs genomes de fragments d'adn etrangers, selon l'une quelconque des phases de traduction possibles, et moyens pour leur fabrication |
| JPS5573868A (en) * | 1978-11-22 | 1980-06-03 | Mitsubishi Electric Corp | Coating method for thin aluminum-silicon alloy film |
| JPS561890A (en) * | 1979-06-15 | 1981-01-10 | Ajinomoto Co Inc | Preparation of l-phenylalanine by fermentation |
-
1981
- 1981-07-17 DE DE19813128411 patent/DE3128411A1/de not_active Ceased
- 1981-07-17 JP JP56112061A patent/JPS57170184A/ja active Pending
- 1981-07-20 FR FR8114056A patent/FR2486961A1/fr active Granted
-
1983
- 1983-01-18 US US06/459,302 patent/US4681852A/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61247392A (ja) * | 1985-02-04 | 1986-11-04 | エンジニツクス インコ−ポレ−テツド | 2種またはより多くのアミノ酸を同時に産生できる組換え微生物 |
| JP2018522536A (ja) * | 2015-05-27 | 2018-08-16 | ランザテク・ニュージーランド・リミテッド | コリスミ酸誘導産物生成のための遺伝子組換え微生物(関連出願の相互参照) |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3128411A1 (de) | 1983-09-15 |
| FR2486961B1 (enExample) | 1985-04-12 |
| US4681852A (en) | 1987-07-21 |
| FR2486961A1 (fr) | 1982-01-22 |
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