JPS57170184A - Mutant of e. coli and production of phenylalanine - Google Patents

Mutant of e. coli and production of phenylalanine

Info

Publication number
JPS57170184A
JPS57170184A JP56112061A JP11206181A JPS57170184A JP S57170184 A JPS57170184 A JP S57170184A JP 56112061 A JP56112061 A JP 56112061A JP 11206181 A JP11206181 A JP 11206181A JP S57170184 A JPS57170184 A JP S57170184A
Authority
JP
Japan
Prior art keywords
phenylalanine
mutant
coli
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56112061A
Other languages
English (en)
Japanese (ja)
Inventor
Edowaado Toraibu Debitsudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unisearch Ltd
Original Assignee
Unisearch Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unisearch Ltd filed Critical Unisearch Ltd
Publication of JPS57170184A publication Critical patent/JPS57170184A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/22Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222Phenylalanine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli

Landscapes

  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP56112061A 1980-07-18 1981-07-17 Mutant of e. coli and production of phenylalanine Pending JPS57170184A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU459080 1980-07-18

Publications (1)

Publication Number Publication Date
JPS57170184A true JPS57170184A (en) 1982-10-20

Family

ID=3695035

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56112061A Pending JPS57170184A (en) 1980-07-18 1981-07-17 Mutant of e. coli and production of phenylalanine

Country Status (4)

Country Link
US (1) US4681852A (enExample)
JP (1) JPS57170184A (enExample)
DE (1) DE3128411A1 (enExample)
FR (1) FR2486961A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61247392A (ja) * 1985-02-04 1986-11-04 エンジニツクス インコ−ポレ−テツド 2種またはより多くのアミノ酸を同時に産生できる組換え微生物
JP2018522536A (ja) * 2015-05-27 2018-08-16 ランザテク・ニュージーランド・リミテッド コリスミ酸誘導産物生成のための遺伝子組換え微生物(関連出願の相互参照)

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CA1236412A (en) * 1983-10-07 1988-05-10 Keith C. Backman Cell lines and methods for fermentation
US4839286A (en) * 1983-10-07 1989-06-13 Biotechnica International, Inc. Method of biosynthesis and cells therefor
US5169768A (en) * 1983-10-07 1992-12-08 Biotechnica International, Inc. Method of biosynthesis of phenylalanine
GB8333797D0 (en) * 1983-12-19 1984-01-25 Searle & Co Starch utilization
JPS6178378A (ja) * 1984-09-27 1986-04-21 Ajinomoto Co Inc 芳香族アミノ酸生合成遺伝子を含有する組換えdna及びそれを有するコリネ型細菌
JPS63500215A (ja) * 1985-06-24 1988-01-28 ザ ヌトラスウイ−ト カンパニ− アミノ酸合成用の複合プラスミド
US4753883A (en) * 1986-05-07 1988-06-28 Biotechnica International, Inc. Enzyme deregulation
KR890003714B1 (ko) * 1987-03-26 1989-09-30 주식회사 미원 유전자 조작 미생물에 의한 l-페닐알라닌 제조방법
KR890003682B1 (ko) * 1987-03-26 1989-09-30 주식회사 미원 유전자조작 미생물에 의한 l-페닐알라닌의 제조방법
US5100775A (en) * 1988-03-16 1992-03-31 Smyczek Peter J Method for conducting nucleic acid hybridization in chamber with precise fluid delivery
US5019509A (en) * 1988-04-20 1991-05-28 Genetics Institute, Inc. Method and compositions for the production of l-alanine and derivatives thereof
US5543052A (en) * 1988-07-28 1996-08-06 Alliedsignal Inc. Process for removal of organic pollutants from waste water
US5580770A (en) * 1989-11-02 1996-12-03 Alliedsignal Inc. Support containing particulate adsorbent and microorganisms for removal of pollutants
US4957686A (en) * 1990-02-06 1990-09-18 Norris Alan H Use of bacteriophages to inhibit dental caries
EP0488424B1 (en) * 1990-11-30 1997-03-05 Ajinomoto Co., Inc. Recombinant DNA sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant DNA sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation
US5168056A (en) * 1991-02-08 1992-12-01 Purdue Research Foundation Enhanced production of common aromatic pathway compounds
DE69126141T2 (de) * 1991-08-26 1997-08-28 Kyowa Hakko Kogyo Kk Verfahren zur herstellung von 4-hydroxy-l-prolin
US5409830A (en) * 1992-12-16 1995-04-25 Miwon Co. Ltd. Method for production of l-phenylalanine by Echerichia coli mutant that is resistant to osmotic pressure
US5776736A (en) * 1992-12-21 1998-07-07 Purdue Research Foundation Deblocking the common pathway of aromatic amino acid synthesis
KR950704500A (ko) * 1992-12-21 1995-11-20 윌리암 디. 그리그스 방향족 아미노산 합성의 경로의 탈차단방법(deblocking the common pathway of aromatic amino acid synthesis)
US5395527A (en) * 1993-07-01 1995-03-07 Eco Equipement Fep Inc. Process and apparatus for treating wastewater in a dynamic, bio sequenced manner
US5629181A (en) * 1993-09-16 1997-05-13 Purdue Research Foundation Synthesis of catechol from biomass-derived carbon sources
US5487987A (en) * 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5487986A (en) * 1994-03-10 1996-01-30 Genzyme Corporation Method for increasing plasmid yield
US5614392A (en) * 1995-06-01 1997-03-25 Food Industry Research And Development Institute Process of L-phenylalanine fermentation
US6274369B1 (en) 1996-02-02 2001-08-14 Invitrogen Corporation Method capable of increasing competency of bacterial cell transformation
WO1997036613A1 (en) 1996-03-29 1997-10-09 Life Technologies, Inc. Method for increasing viability and transformation efficiency of bacteria during storage at low temperatures
AUPO258196A0 (en) * 1996-09-27 1996-10-17 Australian National University, The Method for determining ion channel activity of a substance
EP1005529B1 (en) 1997-02-12 2005-04-27 Invitrogen Corporation Methods for lyophilizing competent cells
US6210937B1 (en) 1997-04-22 2001-04-03 Bechtel Bwxt Idaho, Llc Development of genetically engineered bacteria for production of selected aromatic compounds
US6030819A (en) * 1998-09-28 2000-02-29 General Electric Company Genetically engineered microorganisms and method for producing 4-hydroxybenzoic acid
WO2000073484A1 (en) * 1999-05-28 2000-12-07 University Of North Texas Health Science Center At Fort Worth A global regulator used to enhance the synthesis of aromatic substances
RU2202607C2 (ru) * 2000-03-03 2003-04-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Штамм бактерий methylophilus methylotrophus - продуцент l-фенилаланина (варианты), способ получения l-фенилаланина
US20030091971A1 (en) * 2001-09-14 2003-05-15 Invitrogen Corporation Composition for stabilizing biological materials
KR100608085B1 (ko) * 2004-02-05 2006-08-02 씨제이 주식회사 tyrR 유전자가 불활성화된 L-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한L-쓰레오닌의 제조방법
JP4665613B2 (ja) * 2004-06-15 2011-04-06 味の素株式会社 L−チロシン生産菌及びl−チロシンの製造法
US7482140B2 (en) 2004-06-15 2009-01-27 Ajinomoto Co., Inc. L-tyrosine-producing bacterium and a method for producing L-tyrosine
US20060035310A1 (en) * 2004-08-13 2006-02-16 Millipore Corporation Media for recovery of microorganism in the presence of antibiotics
US7531345B2 (en) * 2005-05-16 2009-05-12 Massachusetts Institute Of Technology Mutations for enhanced tyrosine production
US7582474B2 (en) * 2005-07-11 2009-09-01 Honeywell International Inc. Process reactor with layered packed bed
EP1764415A1 (en) * 2005-09-20 2007-03-21 Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO Microbial production of p-hydroxybenzyl alcohol
US7700328B2 (en) * 2006-06-07 2010-04-20 E.I. Du Pont De Nemours And Company Method for producing an L-tyrosine over-producing bacterial strain
RU2006129690A (ru) 2006-08-16 2008-02-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ
US20080102499A1 (en) * 2006-10-27 2008-05-01 Lori Jean Templeton Method of enhancing L-tyrosine production in recombinant bacteria
JP5714033B2 (ja) 2011-01-31 2015-05-07 旭化成ケミカルズ株式会社 フェニルピルビン酸還元酵素並びに本酵素を用いた光学活性フェニル乳酸及び4−ヒドロキシ−フェニル乳酸の製造方法
WO2012122333A1 (en) 2011-03-08 2012-09-13 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Microbial conversion of glucose to styrene and its derivatives
US20150044755A1 (en) 2012-01-30 2015-02-12 Myriant Corporation Production of muconic acid from genetically engineered microorganisms
US10174346B2 (en) 2013-08-27 2019-01-08 Arizona Board Of Regents On Behalf Of Arizona State University Microorganisms engineered to produce phenol and its derivatives
SG10202008244TA (en) 2016-03-02 2020-10-29 Ptt Global Chemical Public Co Ltd Improved muconic acid production from genetically engineered microorganisms
CN110494560A (zh) 2017-02-06 2019-11-22 齐默尔根公司 通过发酵产生酪胺的经改造的生物合成途径
US11708590B2 (en) 2017-07-18 2023-07-25 Arizona Board Of Regents On Behalf Of Arizona State University Synthetic metabolic funneling for biochemical production
US11613768B2 (en) 2017-07-25 2023-03-28 Arizona Board Of Regents On Behalf Of Arizona State University Microbial production of 2-phenylethanol from renewable substrates
EP3775158A1 (en) 2018-04-06 2021-02-17 Ajinomoto Co., Inc. Agricultural or horticultural composition containing culture broth of bacillus bacterium
CN112080452B (zh) * 2020-08-17 2023-04-28 天津科技大学 一种高产苯乳酸地衣芽孢杆菌基因工程菌、生产苯乳酸的方法和应用

Family Cites Families (7)

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US2973304A (en) * 1958-10-02 1961-02-28 Pfizer & Co C Fermentation process
US3700558A (en) * 1967-11-20 1972-10-24 Lepetit Spa Production of l-tryptophan by fermentation
US3660235A (en) * 1969-08-22 1972-05-02 Ajinomoto Kk Method for producing phenylalanine by fermentation
SU875663A1 (ru) * 1978-06-30 1982-09-15 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штаммы е.coLI ВНИИГенетика VL 334 @ N6 и ВНИИГенетика VL 334 @ N7-продуценты L-треонина и способ их получени
FR2440957A1 (fr) * 1978-11-13 1980-06-06 Pasteur Institut Vecteurs appropries a l'insertion dans leurs genomes de fragments d'adn etrangers, selon l'une quelconque des phases de traduction possibles, et moyens pour leur fabrication
JPS5573868A (en) * 1978-11-22 1980-06-03 Mitsubishi Electric Corp Coating method for thin aluminum-silicon alloy film
JPS561890A (en) * 1979-06-15 1981-01-10 Ajinomoto Co Inc Preparation of l-phenylalanine by fermentation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61247392A (ja) * 1985-02-04 1986-11-04 エンジニツクス インコ−ポレ−テツド 2種またはより多くのアミノ酸を同時に産生できる組換え微生物
JP2018522536A (ja) * 2015-05-27 2018-08-16 ランザテク・ニュージーランド・リミテッド コリスミ酸誘導産物生成のための遺伝子組換え微生物(関連出願の相互参照)

Also Published As

Publication number Publication date
DE3128411A1 (de) 1983-09-15
FR2486961B1 (enExample) 1985-04-12
US4681852A (en) 1987-07-21
FR2486961A1 (fr) 1982-01-22

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