DE3116890A1 - "2-guanidinothiazolderivate" - Google Patents

"2-guanidinothiazolderivate"

Info

Publication number
DE3116890A1
DE3116890A1 DE19813116890 DE3116890A DE3116890A1 DE 3116890 A1 DE3116890 A1 DE 3116890A1 DE 19813116890 DE19813116890 DE 19813116890 DE 3116890 A DE3116890 A DE 3116890A DE 3116890 A1 DE3116890 A1 DE 3116890A1
Authority
DE
Germany
Prior art keywords
guanidino
thiazole
general formula
group
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19813116890
Other languages
German (de)
English (en)
Inventor
Kentaro Kyoto Hirai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE3116890A1 publication Critical patent/DE3116890A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19813116890 1980-04-29 1981-04-28 "2-guanidinothiazolderivate" Ceased DE3116890A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14494680A 1980-04-29 1980-04-29

Publications (1)

Publication Number Publication Date
DE3116890A1 true DE3116890A1 (de) 1982-03-04

Family

ID=22510873

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813116890 Ceased DE3116890A1 (de) 1980-04-29 1981-04-28 "2-guanidinothiazolderivate"

Country Status (16)

Country Link
JP (1) JPS574977A (ja)
AR (1) AR231538A1 (ja)
AU (1) AU540239B2 (ja)
BE (1) BE888602A (ja)
CH (1) CH646964A5 (ja)
DE (1) DE3116890A1 (ja)
DK (1) DK188881A (ja)
ES (1) ES501736A0 (ja)
FR (1) FR2481280A1 (ja)
GB (1) GB2076397B (ja)
IE (1) IE51151B1 (ja)
IL (1) IL62747A (ja)
IT (1) IT1146750B (ja)
NL (1) NL8102099A (ja)
NZ (1) NZ196923A (ja)
SE (1) SE452462B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3332138A1 (de) * 1982-12-03 1984-06-07 Kotobuki Seiyaku Co. Ltd., Nagano 2,4-substituierte thiazolderivate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501747A (en) * 1982-05-10 1985-02-26 Sanofi Certain amide derivatives of 2-guanidino-thiazoles and compositions containing same
FR2531705B1 (fr) * 1982-08-13 1986-12-05 Sanofi Sa Amidobenzamides, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant
EP0123741A1 (en) * 1983-04-26 1984-11-07 Shionogi & Co., Ltd. 2-Guanidino-4-hydroxymethylthiazole and derivatives thereof
US4680300A (en) * 1985-01-10 1987-07-14 Syntex (U.S.A.) Inc. Anti-inflammatory guanidines
US4837316A (en) * 1985-08-29 1989-06-06 Fujirebio Kabushiki Kaisha Alkylamide derivatives with H2 -receptor antagonistic and cytoprotective action
EP0385525B1 (en) * 1989-03-03 1994-04-13 Akzo Nv Aminoethylthiazole and aminoethyloxazole derivatives.

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
US4165377A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidino imidazoles and thiazoles
JPS5555174A (en) 1978-10-16 1980-04-22 Ici Ltd Branched chain heterocyclic derivative*its manufacture and pharmaceutic composition containing it and having secretion controlling activity
DE3008056A1 (de) * 1979-03-06 1980-09-18 Yamanouchi Pharma Co Ltd Guanidinothiazolverbindungen, verfahren zu ihrer herstellung und arzneimittel
EP0030092A1 (en) * 1979-11-13 1981-06-10 Imperial Chemical Industries Plc Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
DE3150334A1 (de) * 1980-12-19 1982-07-15 Shionogi & Co., Ltd., Osaka "bis-(carboxamid)-derivate"

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003640B1 (en) * 1978-01-18 1982-01-27 Imperial Chemical Industries Plc Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
US4309435A (en) * 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
DE3069889D1 (en) * 1979-01-18 1985-02-14 Ici Plc Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
JPS5754177A (ja) * 1980-09-19 1982-03-31 Teikoku Hormone Mfg Co Ltd Chikanchiazoorujudotai

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
US4165377A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidino imidazoles and thiazoles
JPS5555174A (en) 1978-10-16 1980-04-22 Ici Ltd Branched chain heterocyclic derivative*its manufacture and pharmaceutic composition containing it and having secretion controlling activity
EP0010893A1 (en) * 1978-10-16 1980-05-14 Imperial Chemical Industries Plc Antisecretory branched-chain heterocyclic guanidine derivatives, processes for their manufacture, intermediates, and pharmaceutical compositions containing said derivatives
DE3008056A1 (de) * 1979-03-06 1980-09-18 Yamanouchi Pharma Co Ltd Guanidinothiazolverbindungen, verfahren zu ihrer herstellung und arzneimittel
EP0030092A1 (en) * 1979-11-13 1981-06-10 Imperial Chemical Industries Plc Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
DE3150334A1 (de) * 1980-12-19 1982-07-15 Shionogi & Co., Ltd., Osaka "bis-(carboxamid)-derivate"

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JP-Kokai 55-55 174 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3332138A1 (de) * 1982-12-03 1984-06-07 Kotobuki Seiyaku Co. Ltd., Nagano 2,4-substituierte thiazolderivate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
FR2481280A1 (fr) 1981-10-30
IL62747A0 (en) 1981-06-29
CH646964A5 (de) 1984-12-28
SE452462B (sv) 1987-11-30
ES8206501A1 (es) 1982-08-16
IT8167585A0 (it) 1981-04-29
AU540239B2 (en) 1984-11-08
SE8102683L (sv) 1981-10-30
AR231538A1 (es) 1984-12-28
ES501736A0 (es) 1982-08-16
NL8102099A (nl) 1981-11-16
GB2076397A (en) 1981-12-02
JPH027952B2 (ja) 1990-02-21
GB2076397B (en) 1984-02-08
NZ196923A (en) 1983-12-16
JPS574977A (en) 1982-01-11
IT1146750B (it) 1986-11-19
BE888602A (fr) 1981-10-28
IE810956L (en) 1981-10-29
IE51151B1 (en) 1986-10-15
IL62747A (en) 1984-10-31
DK188881A (da) 1981-10-30
AU6996681A (en) 1981-11-05
FR2481280B1 (ja) 1983-10-28

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection