JPS574977A - 2-guanidinothiazole derivative - Google Patents

2-guanidinothiazole derivative

Info

Publication number
JPS574977A
JPS574977A JP6473981A JP6473981A JPS574977A JP S574977 A JPS574977 A JP S574977A JP 6473981 A JP6473981 A JP 6473981A JP 6473981 A JP6473981 A JP 6473981A JP S574977 A JPS574977 A JP S574977A
Authority
JP
Japan
Prior art keywords
formula
compound shown
replaced
sulfamoylbenzamide
alkadienyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6473981A
Other languages
English (en)
Other versions
JPH027952B2 (ja
Inventor
Kentaro Hirai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of JPS574977A publication Critical patent/JPS574977A/ja
Publication of JPH027952B2 publication Critical patent/JPH027952B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
JP6473981A 1980-04-29 1981-04-28 2-guanidinothiazole derivative Granted JPS574977A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14494680A 1980-04-29 1980-04-29

Publications (2)

Publication Number Publication Date
JPS574977A true JPS574977A (en) 1982-01-11
JPH027952B2 JPH027952B2 (ja) 1990-02-21

Family

ID=22510873

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6473981A Granted JPS574977A (en) 1980-04-29 1981-04-28 2-guanidinothiazole derivative

Country Status (16)

Country Link
JP (1) JPS574977A (ja)
AR (1) AR231538A1 (ja)
AU (1) AU540239B2 (ja)
BE (1) BE888602A (ja)
CH (1) CH646964A5 (ja)
DE (1) DE3116890A1 (ja)
DK (1) DK188881A (ja)
ES (1) ES8206501A1 (ja)
FR (1) FR2481280A1 (ja)
GB (1) GB2076397B (ja)
IE (1) IE51151B1 (ja)
IL (1) IL62747A (ja)
IT (1) IT1146750B (ja)
NL (1) NL8102099A (ja)
NZ (1) NZ196923A (ja)
SE (1) SE452462B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531705B1 (fr) * 1982-08-13 1986-12-05 Sanofi Sa Amidobenzamides, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant
US4501747A (en) * 1982-05-10 1985-02-26 Sanofi Certain amide derivatives of 2-guanidino-thiazoles and compositions containing same
JPS59104370A (ja) * 1982-12-03 1984-06-16 Kotobuki Seiyaku Kk チアゾ−ル誘導体及びその製造方法
GB2138803B (en) * 1983-04-26 1986-06-18 Shionogi & Co 2-guanidino-4-hydroxymethylthiazole and derivatives thereof
US4680300A (en) * 1985-01-10 1987-07-14 Syntex (U.S.A.) Inc. Anti-inflammatory guanidines
US4837316A (en) * 1985-08-29 1989-06-06 Fujirebio Kabushiki Kaisha Alkylamide derivatives with H2 -receptor antagonistic and cytoprotective action
EP0385525B1 (en) * 1989-03-03 1994-04-13 Akzo Nv Aminoethylthiazole and aminoethyloxazole derivatives.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5754177A (ja) * 1980-09-19 1982-03-31 Teikoku Hormone Mfg Co Ltd Chikanchiazoorujudotai

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
NO781300L (no) * 1977-04-20 1978-10-23 Ici Ltd Fremgangsmaate for fremstilling av fysiologisk aktive guanidinderivater
EP0003640B1 (en) * 1978-01-18 1982-01-27 Imperial Chemical Industries Plc Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
DE2966646D1 (en) * 1978-10-16 1984-03-15 Ici Plc Antisecretory branched-chain heterocyclic guanidine derivatives, processes for their manufacture, intermediates, and pharmaceutical compositions containing said derivatives
US4309435A (en) * 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
EP0014057B1 (en) * 1979-01-18 1985-01-02 Imperial Chemical Industries Plc Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
PH16099A (en) * 1979-03-06 1983-06-24 Yamanouchi Pharma Co Ltd Guanidinothiazole compounds,process for preparing them and medical composition containing them
GR71929B (ja) * 1979-11-13 1983-08-19 Ici Ltd
JPS57102852A (en) * 1980-12-19 1982-06-26 Shionogi & Co Ltd Dicarboxylic acid diamide

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5754177A (ja) * 1980-09-19 1982-03-31 Teikoku Hormone Mfg Co Ltd Chikanchiazoorujudotai

Also Published As

Publication number Publication date
IT1146750B (it) 1986-11-19
BE888602A (fr) 1981-10-28
GB2076397B (en) 1984-02-08
AR231538A1 (es) 1984-12-28
GB2076397A (en) 1981-12-02
SE8102683L (sv) 1981-10-30
DK188881A (da) 1981-10-30
AU540239B2 (en) 1984-11-08
NZ196923A (en) 1983-12-16
JPH027952B2 (ja) 1990-02-21
ES501736A0 (es) 1982-08-16
IE51151B1 (en) 1986-10-15
AU6996681A (en) 1981-11-05
NL8102099A (nl) 1981-11-16
SE452462B (sv) 1987-11-30
IL62747A (en) 1984-10-31
CH646964A5 (de) 1984-12-28
FR2481280A1 (fr) 1981-10-30
IE810956L (en) 1981-10-29
IT8167585A0 (it) 1981-04-29
DE3116890A1 (de) 1982-03-04
ES8206501A1 (es) 1982-08-16
IL62747A0 (en) 1981-06-29
FR2481280B1 (ja) 1983-10-28

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