JPS57142977A - Tetrazole derivative - Google Patents
Tetrazole derivativeInfo
- Publication number
- JPS57142977A JPS57142977A JP2910681A JP2910681A JPS57142977A JP S57142977 A JPS57142977 A JP S57142977A JP 2910681 A JP2910681 A JP 2910681A JP 2910681 A JP2910681 A JP 2910681A JP S57142977 A JPS57142977 A JP S57142977A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- action
- compound
- substituent groups
- lower alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formulaI[R1 is lower alkyl or phenyl; A is lower alkylene; R2 is OH, lower alkoxy or -NR3R4; R3 and R4 are H, lower alkyl which may have 1W2 substituent groups (OH, furyl, pyridyl, etc.), cycloalkyl which may have 1W2 substituent groups (OH or lower alkoxy), phenyl which may have 1W2 substituent groups (lower alkyl, lower alkoxy, halogen, etc.), thiazolyl, etc.].
EXAMPLE: 4-(5-Methyl-1,2,3,4-tetrazol-1-yl)butyric acid methyl ester.
USE: Remedy and preventive for peptic ulcer and duodenal ulcer. It has low side effects e.g. central nervous action such as hypnotic action, anticholinergic action, peristole suppressing action, etc., and low toxicity.
PROCESS: The compound of formulaI wherein R2 is OR5 can be prepared by reacting the compound of formula II (R5 is lower alkyl) with PCl5, and then reacting the product with HN3.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2910681A JPS57142977A (en) | 1981-02-27 | 1981-02-27 | Tetrazole derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2910681A JPS57142977A (en) | 1981-02-27 | 1981-02-27 | Tetrazole derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57142977A true JPS57142977A (en) | 1982-09-03 |
JPH0227345B2 JPH0227345B2 (en) | 1990-06-15 |
Family
ID=12267078
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2910681A Granted JPS57142977A (en) | 1981-02-27 | 1981-02-27 | Tetrazole derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57142977A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011108724A1 (en) * | 2010-03-04 | 2011-09-09 | 味の素株式会社 | Prophylactic or therapeutic agent for diabetes or obesity |
WO2011108690A1 (en) * | 2010-03-04 | 2011-09-09 | 味の素株式会社 | Alkylamine derivative |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6423464A (en) * | 1987-07-17 | 1989-01-26 | Matsushita Electric Ind Co Ltd | Optical disk reproducing device |
-
1981
- 1981-02-27 JP JP2910681A patent/JPS57142977A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6423464A (en) * | 1987-07-17 | 1989-01-26 | Matsushita Electric Ind Co Ltd | Optical disk reproducing device |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011108724A1 (en) * | 2010-03-04 | 2011-09-09 | 味の素株式会社 | Prophylactic or therapeutic agent for diabetes or obesity |
WO2011108690A1 (en) * | 2010-03-04 | 2011-09-09 | 味の素株式会社 | Alkylamine derivative |
JP5240398B2 (en) * | 2010-03-04 | 2013-07-17 | 味の素株式会社 | Alkylamine derivatives |
CN103951615A (en) * | 2010-03-04 | 2014-07-30 | 味之素株式会社 | Alkylamine derivative |
KR20150002891A (en) * | 2010-03-04 | 2015-01-07 | 아지노모토 가부시키가이샤 | Alkylamine derivative |
JP5761173B2 (en) * | 2010-03-04 | 2015-08-12 | 味の素株式会社 | Preventive or therapeutic agent for diabetes or obesity |
US9150505B2 (en) | 2010-03-04 | 2015-10-06 | Ajinomoto Co., Inc. | Prophylactic or therapeutic agent for diabetes or obesity |
US9253997B2 (en) | 2010-03-04 | 2016-02-09 | Ajinomoto Co., Inc. | Alkylamine derivative |
US9561216B2 (en) | 2010-03-04 | 2017-02-07 | Ea Pharma Co., Ltd. | Alkylamine derivative |
USRE49569E1 (en) | 2010-03-04 | 2023-07-04 | Ea Pharma Co., Ltd. | Alkylamine derivative |
Also Published As
Publication number | Publication date |
---|---|
JPH0227345B2 (en) | 1990-06-15 |
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