DE3014685A1 - Polycyclische verbindungen und verfahren zu deren herstellung - Google Patents

Polycyclische verbindungen und verfahren zu deren herstellung

Info

Publication number
DE3014685A1
DE3014685A1 DE19803014685 DE3014685A DE3014685A1 DE 3014685 A1 DE3014685 A1 DE 3014685A1 DE 19803014685 DE19803014685 DE 19803014685 DE 3014685 A DE3014685 A DE 3014685A DE 3014685 A1 DE3014685 A1 DE 3014685A1
Authority
DE
Germany
Prior art keywords
compound
formula
hydroxy
hydrogen
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19803014685
Other languages
German (de)
English (en)
Inventor
Pierre-Alain Carrupt
Pierre Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH375179A external-priority patent/CH646172A5/de
Priority claimed from CH78380A external-priority patent/CH645113A5/de
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE3014685A1 publication Critical patent/DE3014685A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE19803014685 1979-04-20 1980-04-16 Polycyclische verbindungen und verfahren zu deren herstellung Ceased DE3014685A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH375179A CH646172A5 (en) 1979-04-20 1979-04-20 1,2,3,4,9,10-Hexahydro-5,8-dihydroxy-2,3-dimethylene-1,4-epoxyanth racene, its dimethyl ether and their preparation
CH78380A CH645113A5 (en) 1980-01-31 1980-01-31 Polycyclic compounds and process for their preparation

Publications (1)

Publication Number Publication Date
DE3014685A1 true DE3014685A1 (de) 1980-11-06

Family

ID=25685676

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803014685 Ceased DE3014685A1 (de) 1979-04-20 1980-04-16 Polycyclische verbindungen und verfahren zu deren herstellung

Country Status (6)

Country Link
US (2) US4264510A (OSRAM)
DE (1) DE3014685A1 (OSRAM)
FR (3) FR2454433A1 (OSRAM)
GB (2) GB2051044B (OSRAM)
IT (1) IT1130074B (OSRAM)
NL (1) NL8002103A (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515720A (en) * 1983-03-11 1985-05-07 Oregon Graduate Center For Study & Research Method of synthesizing a late-stage intermediate to 11-deoxydaunorubicin and 11-deoxyadriamycin, and two precursors to the object intermediate
US4489206A (en) * 1983-05-13 1984-12-18 Adria Laboratories, Inc. Synthesis of (+)-4-demethoxydaunomycinone
US7053191B2 (en) * 2003-05-21 2006-05-30 Solux Corporation Method of preparing 4-R-substituted 4-demethoxydaunorubicin
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
US8846882B2 (en) 2011-04-29 2014-09-30 Synbias Pharma Ag Method of producing 4-demethoxydaunorubicin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2987545A (en) * 1959-01-30 1961-06-06 American Cyanamid Co Process of converting esters into amides
US3947517A (en) * 1969-06-12 1976-03-30 Research Corporation Stereoselective introduction of tetracyclines hydroxyl group at 12(a) position in synthesis of tetracyclines
FI60194C (fi) * 1972-07-28 1981-12-10 Ciba Geigy Ag Foerfarande foer framstaellning av bensil-monoketaler
US4116981A (en) * 1977-05-02 1978-09-26 Yuh-Geng Tsay 5,12-epoxy-naphthacene-6,11-dione derivatives
US4161480A (en) * 1978-06-05 1979-07-17 G. D. Searle & Co. Intermediates for the synthesis of 4-demethoxydaunorubicin

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Chem. Abstr. Subject Index, 1967-71, S. 113 17S *
Nachr. Chem. Tech. Lab. 27, 1979, S. 7-8 *
Tetrahedron Lett. 47, 1976, S. 4271-4274 *

Also Published As

Publication number Publication date
IT1130074B (it) 1986-06-11
FR2454433B1 (OSRAM) 1984-01-20
FR2472573B1 (OSRAM) 1984-01-20
FR2472573A1 (fr) 1981-07-03
US4264510A (en) 1981-04-28
GB8301475D0 (en) 1983-02-23
IT8020862A0 (it) 1980-03-21
GB2051044B (en) 1983-11-30
GB2120654B (en) 1984-06-20
NL8002103A (nl) 1980-10-22
GB2051044A (en) 1981-01-14
GB2120654A (en) 1983-12-07
FR2472572A1 (fr) 1981-07-03
FR2472572B1 (OSRAM) 1984-01-20
US4298535A (en) 1981-11-03
FR2454433A1 (fr) 1980-11-14

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Legal Events

Date Code Title Description
OB Request for examination as to novelty
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: LEDERER, F., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUEN

8105 Search report available
8131 Rejection