DE3009064C2 - Verfahren zur Herstellung eines Tollwutimpfstoffes - Google Patents

Verfahren zur Herstellung eines Tollwutimpfstoffes

Info

Publication number
DE3009064C2
DE3009064C2 DE3009064A DE3009064A DE3009064C2 DE 3009064 C2 DE3009064 C2 DE 3009064C2 DE 3009064 A DE3009064 A DE 3009064A DE 3009064 A DE3009064 A DE 3009064A DE 3009064 C2 DE3009064 C2 DE 3009064C2
Authority
DE
Germany
Prior art keywords
vaccine
rabies
embryos
virus
embryo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3009064A
Other languages
German (de)
English (en)
Other versions
DE3009064A1 (de
Inventor
Klaus R. Dr.phil. Dr.med.vet. Flamatt Schell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten filed Critical Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Publication of DE3009064A1 publication Critical patent/DE3009064A1/de
Application granted granted Critical
Publication of DE3009064C2 publication Critical patent/DE3009064C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/205—Rhabdoviridae, e.g. rabies virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20151—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE3009064A 1979-04-10 1980-03-10 Verfahren zur Herstellung eines Tollwutimpfstoffes Expired DE3009064C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH341479A CH638985A5 (de) 1979-04-10 1979-04-10 Verfahren zur herstellung eines tollwutimpfstoffes und danach erhaltener impfstoff.

Publications (2)

Publication Number Publication Date
DE3009064A1 DE3009064A1 (de) 1980-10-23
DE3009064C2 true DE3009064C2 (de) 1984-01-12

Family

ID=4255467

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3009064A Expired DE3009064C2 (de) 1979-04-10 1980-03-10 Verfahren zur Herstellung eines Tollwutimpfstoffes

Country Status (7)

Country Link
US (1) US4255520A (enExample)
BE (1) BE882684A (enExample)
CA (1) CA1127081A (enExample)
CH (1) CH638985A5 (enExample)
DE (1) DE3009064C2 (enExample)
FR (1) FR2453651A1 (enExample)
GB (1) GB2048066B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3014189A1 (de) * 1980-04-14 1981-10-15 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur herstellung eines immunogenen membranproteinaggregats von influenza-, parainfluenza- und rhabdo-viren
JPS6147187A (ja) * 1984-08-10 1986-03-07 Chemo Sero Therapeut Res Inst 狂犬病ウイルスの精製方法
ATE69383T1 (de) * 1985-11-22 1991-11-15 Schweiz Serum & Impfinst Verfahren zur herstellung eines tollwutimpfstoffes und nach diesem verfahren erhaltener impfstoff.
US20040023358A1 (en) * 2001-12-21 2004-02-05 Wyeth Avian embryo particulate biomass for the production of virus antigens

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2204064A (en) * 1938-05-13 1940-06-11 Joseph W Beard Equine encephalomyelitis vaccine
US2445300A (en) * 1941-12-05 1948-07-13 Univ Pennsylvania Virus vaccines
US2506345A (en) * 1946-10-01 1950-05-02 American Cyanamid Co Method of separating live viruses from nonviral protein matter
US2773800A (en) * 1953-04-28 1956-12-11 Lilly Co Eli Rabies vaccine production
CH331368A (fr) * 1953-08-21 1958-07-15 American Cyanamid Co Procédé pour atténuer le virus rabique virulent en une forme non pathogène sans perte appréciable de ses propriétés antigènes
US2768114A (en) * 1953-08-21 1956-10-23 American Cyanamid Co Rabies vaccines and methods of preparing the same
US3155589A (en) * 1958-04-14 1964-11-03 Upjohn Co Parenteral extravascular injectable vaccines for simultaneous immunization of canidae against rabies, canine distemper, and infectious canine hepatitis
US3029190A (en) * 1959-08-04 1962-04-10 Hanson Robert Paul Selection of neurotropic viral strains and preparation of vaccines therefrom
US3143470A (en) * 1961-04-24 1964-08-04 Parke Davis & Co Rabies virus propagation in embryonic cells maintained in a medium containing pancreatic digest of casein
US3156620A (en) * 1962-01-10 1964-11-10 American Cyanamid Co Attenuated live rabies vaccine and method of preparing the same
US3255080A (en) * 1962-08-06 1966-06-07 Dow Chemical Co Live rabies virus vaccine and method for the production thereof
US3397267A (en) * 1964-09-21 1968-08-13 Research Corp Method of producing rabies vaccine
US3415926A (en) * 1966-03-09 1968-12-10 American Home Prod Equine encephalomyelitis vaccine
US3859168A (en) * 1967-06-22 1975-01-07 Behringwerke Ag Process of inactivating rabies virus
US3585266A (en) * 1969-02-24 1971-06-15 Dow Chemical Co Live rabies virus vaccine and method for the production thereof
US3674862A (en) * 1970-04-02 1972-07-04 Lilly Co Eli Live attenuated rabies virus vaccine and process therefor
US3973000A (en) * 1972-02-04 1976-08-03 Eli Lilly And Company Process for purified rabies vaccine
FR2201079A1 (en) * 1972-09-22 1974-04-26 Inst Francais D Immunologie Viruses prepn. by fractional centrifugation - using liquids of graded densities to displace impurities
US4071618A (en) * 1974-09-03 1978-01-31 Research Foundation For Microbial Diseases Of Osaka University Process for preparing virus disease live vaccines
US4040904A (en) * 1975-07-21 1977-08-09 Slater Eban A Novel rabies virus vaccine and processes
DE2616407C3 (de) * 1976-04-14 1980-02-21 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tollwut-Impfstoffs

Also Published As

Publication number Publication date
US4255520A (en) 1981-03-10
DE3009064A1 (de) 1980-10-23
GB2048066B (en) 1983-04-20
GB2048066A (en) 1980-12-10
BE882684A (fr) 1980-10-08
CA1127081A (en) 1982-07-06
FR2453651A1 (fr) 1980-11-07
FR2453651B1 (enExample) 1983-08-19
CH638985A5 (de) 1983-10-31

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: VON FUENER, A., DIPL.-CHEM. DR.RER.NAT. EBBINGHAUS

8126 Change of the secondary classification

Ipc: ENTFAELLT

D2 Grant after examination
8364 No opposition during term of opposition