DE2929115A1 - Verfahren zur herstellung von luciferin - Google Patents

Verfahren zur herstellung von luciferin

Info

Publication number
DE2929115A1
DE2929115A1 DE19792929115 DE2929115A DE2929115A1 DE 2929115 A1 DE2929115 A1 DE 2929115A1 DE 19792929115 DE19792929115 DE 19792929115 DE 2929115 A DE2929115 A DE 2929115A DE 2929115 A1 DE2929115 A1 DE 2929115A1
Authority
DE
Germany
Prior art keywords
chloro
iodotrimethylsilane
mono
reaction
luciferin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19792929115
Other languages
German (de)
English (en)
Inventor
Hans-Georg Dr Rer Nat Batz
Karl Dr Rer Nat Wulff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19792929115 priority Critical patent/DE2929115A1/de
Priority to IL60362A priority patent/IL60362A/xx
Priority to SU802937845A priority patent/SU1055332A3/ru
Priority to AT80104081T priority patent/ATE1287T1/de
Priority to DE8080104081T priority patent/DE3060623D1/de
Priority to EP80104081A priority patent/EP0024525B1/de
Priority to JP9629280A priority patent/JPS5616480A/ja
Publication of DE2929115A1 publication Critical patent/DE2929115A1/de
Priority to US07/095,122 priority patent/US4826989A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19792929115 1979-07-18 1979-07-18 Verfahren zur herstellung von luciferin Withdrawn DE2929115A1 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
DE19792929115 DE2929115A1 (de) 1979-07-18 1979-07-18 Verfahren zur herstellung von luciferin
IL60362A IL60362A (en) 1979-07-18 1980-06-19 Process for the preparation of luciferin and derivatives thereof
SU802937845A SU1055332A3 (ru) 1979-07-18 1980-06-20 Способ получени 2-циано-6-оксибензтиазола и его варианты
AT80104081T ATE1287T1 (de) 1979-07-18 1980-07-14 Verfahren zur herstellung von luciferin und seinen derivaten.
DE8080104081T DE3060623D1 (en) 1979-07-18 1980-07-14 Process for the preparation of luciferin and its derivatives
EP80104081A EP0024525B1 (de) 1979-07-18 1980-07-14 Verfahren zur Herstellung von Luciferin und seinen Derivaten
JP9629280A JPS5616480A (en) 1979-07-18 1980-07-16 Manufacture of luciferines
US07/095,122 US4826989A (en) 1979-07-18 1987-09-10 Process for the preparation of luciferin compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792929115 DE2929115A1 (de) 1979-07-18 1979-07-18 Verfahren zur herstellung von luciferin

Publications (1)

Publication Number Publication Date
DE2929115A1 true DE2929115A1 (de) 1981-02-12

Family

ID=6076080

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19792929115 Withdrawn DE2929115A1 (de) 1979-07-18 1979-07-18 Verfahren zur herstellung von luciferin
DE8080104081T Expired DE3060623D1 (en) 1979-07-18 1980-07-14 Process for the preparation of luciferin and its derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8080104081T Expired DE3060623D1 (en) 1979-07-18 1980-07-14 Process for the preparation of luciferin and its derivatives

Country Status (7)

Country Link
US (1) US4826989A (https=)
EP (1) EP0024525B1 (https=)
JP (1) JPS5616480A (https=)
AT (1) ATE1287T1 (https=)
DE (2) DE2929115A1 (https=)
IL (1) IL60362A (https=)
SU (1) SU1055332A3 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3537877A1 (de) * 1985-10-24 1987-04-30 Geiger Reinhard Luciferin-derivate und immunoassays unter einsatz derartiger luciferin-derivate
DE3700908A1 (de) * 1987-01-14 1988-07-28 Geiger Reinhard Aminoluciferine, verfahren zu deren herstellung und deren verwendung bei der bestimmung von enzymaktivitaeten
JP3169216B2 (ja) * 1988-07-08 2001-05-21 プロメガ・バイオサイエンシーズ・インコーポレイテッド 蛍光性ベンゾチアゾール誘導体の製法及び用途
DE3916729A1 (de) * 1989-05-23 1990-12-06 Behringwerke Ag Fluorogene verbindungen und ihre verwendung
US5412625A (en) * 1990-02-05 1995-05-02 Duchek; Donna Structural graphic display
EP1546162B1 (en) * 2002-09-20 2011-06-22 Promega Corporation Luminescence-based methods and probes for measuring cytochrome p450 activity
EP2272972A1 (en) * 2005-05-31 2011-01-12 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
RU2284999C1 (ru) * 2005-07-06 2006-10-10 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Способ получения 2-циан-6-метоксибензтиазола
US8288559B2 (en) * 2008-08-18 2012-10-16 Promega Corporation Luminogenic compounds and methods to detect cytochrome P450 3A enzymes
US20110201781A1 (en) * 2008-09-16 2011-08-18 Jianghong Rao Cysteine labeling system and method of use thereof
US9790537B2 (en) 2014-01-29 2017-10-17 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
CN109456281A (zh) * 2018-12-26 2019-03-12 安徽工大化工科技有限公司 一种2-氯-6-甲氧基苯并噻唑的制备方法
CN114729352A (zh) * 2019-09-26 2022-07-08 维迪亚西里梅迪科学技术研究所 荧光素衍生物及其合成方法
US20240182410A1 (en) * 2021-03-19 2024-06-06 Kanto Denka Kogyo Co., Ltd. D-luciferin, d-luciferin derivative, precursor of these compounds and method for producing these compounds

Also Published As

Publication number Publication date
EP0024525B1 (de) 1982-06-30
SU1055332A3 (ru) 1983-11-15
IL60362A0 (en) 1980-09-16
EP0024525A1 (de) 1981-03-11
JPH0150704B2 (https=) 1989-10-31
US4826989A (en) 1989-05-02
DE3060623D1 (en) 1982-08-19
JPS5616480A (en) 1981-02-17
IL60362A (en) 1985-02-28
ATE1287T1 (de) 1982-07-15

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee