IL60362A - Process for the preparation of luciferin and derivatives thereof - Google Patents
Process for the preparation of luciferin and derivatives thereofInfo
- Publication number
- IL60362A IL60362A IL60362A IL6036280A IL60362A IL 60362 A IL60362 A IL 60362A IL 60362 A IL60362 A IL 60362A IL 6036280 A IL6036280 A IL 6036280A IL 60362 A IL60362 A IL 60362A
- Authority
- IL
- Israel
- Prior art keywords
- luciferin
- preparation
- demethylation
- reaction
- hydroxyl group
- Prior art date
Links
- IGXWBGJHJZYPQS-SSDOTTSWSA-N D-Luciferin Chemical compound OC(=O)[C@H]1CSC(C=2SC3=CC=C(O)C=C3N=2)=N1 IGXWBGJHJZYPQS-SSDOTTSWSA-N 0.000 title abstract 2
- CYCGRDQQIOGCKX-UHFFFAOYSA-N Dehydro-luciferin Natural products OC(=O)C1=CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 CYCGRDQQIOGCKX-UHFFFAOYSA-N 0.000 title abstract 2
- BJGNCJDXODQBOB-UHFFFAOYSA-N Fivefly Luciferin Natural products OC(=O)C1CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 BJGNCJDXODQBOB-UHFFFAOYSA-N 0.000 title abstract 2
- DDWFXDSYGUXRAY-UHFFFAOYSA-N Luciferin Natural products CCc1c(C)c(CC2NC(=O)C(=C2C=C)C)[nH]c1Cc3[nH]c4C(=C5/NC(CC(=O)O)C(C)C5CC(=O)O)CC(=O)c4c3C DDWFXDSYGUXRAY-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 230000017858 demethylation Effects 0.000 abstract 2
- 238000010520 demethylation reaction Methods 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- CSRZQMIRAZTJOY-UHFFFAOYSA-N trimethylsilyl iodide Chemical compound C[Si](C)(C)I CSRZQMIRAZTJOY-UHFFFAOYSA-N 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- XUJNEKJLAYXESH-UWTATZPHSA-N D-Cysteine Chemical compound SC[C@@H](N)C(O)=O XUJNEKJLAYXESH-UWTATZPHSA-N 0.000 abstract 1
- 229930195710 D‐cysteine Natural products 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 1
- KXFSUVJPEQYUGN-UHFFFAOYSA-N trimethyl(phenyl)silane Chemical compound C[Si](C)(C)C1=CC=CC=C1 KXFSUVJPEQYUGN-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792929115 DE2929115A1 (de) | 1979-07-18 | 1979-07-18 | Verfahren zur herstellung von luciferin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL60362A0 IL60362A0 (en) | 1980-09-16 |
| IL60362A true IL60362A (en) | 1985-02-28 |
Family
ID=6076080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL60362A IL60362A (en) | 1979-07-18 | 1980-06-19 | Process for the preparation of luciferin and derivatives thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4826989A (xx) |
| EP (1) | EP0024525B1 (xx) |
| JP (1) | JPS5616480A (xx) |
| AT (1) | ATE1287T1 (xx) |
| DE (2) | DE2929115A1 (xx) |
| IL (1) | IL60362A (xx) |
| SU (1) | SU1055332A3 (xx) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3537877A1 (de) * | 1985-10-24 | 1987-04-30 | Geiger Reinhard | Luciferin-derivate und immunoassays unter einsatz derartiger luciferin-derivate |
| DE3700908A1 (de) * | 1987-01-14 | 1988-07-28 | Geiger Reinhard | Aminoluciferine, verfahren zu deren herstellung und deren verwendung bei der bestimmung von enzymaktivitaeten |
| JP3169216B2 (ja) * | 1988-07-08 | 2001-05-21 | プロメガ・バイオサイエンシーズ・インコーポレイテッド | 蛍光性ベンゾチアゾール誘導体の製法及び用途 |
| DE3916729A1 (de) * | 1989-05-23 | 1990-12-06 | Behringwerke Ag | Fluorogene verbindungen und ihre verwendung |
| US5412625A (en) * | 1990-02-05 | 1995-05-02 | Duchek; Donna | Structural graphic display |
| ATE513838T1 (de) | 2002-09-20 | 2011-07-15 | Promega Corp | Auf lumineszenz basierende verfahren und sonden zur messung der cytochrom-p450-aktivität |
| EP1885875B1 (en) * | 2005-05-31 | 2019-05-22 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| EP2323996B1 (en) * | 2008-08-18 | 2014-10-22 | Promega Corporation | Luminogenic compounds and methods to detect cytochrome p450 3a enzymes |
| WO2010033647A2 (en) * | 2008-09-16 | 2010-03-25 | Stanford University | Cysteine labeling system and method of use thereof |
| WO2015116867A1 (en) | 2014-01-29 | 2015-08-06 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| CN109456281A (zh) * | 2018-12-26 | 2019-03-12 | 安徽工大化工科技有限公司 | 一种2-氯-6-甲氧基苯并噻唑的制备方法 |
| JP7194404B1 (ja) * | 2021-03-19 | 2022-12-22 | 関東電化工業株式会社 | Ｄ－ルシフェリン及びｄ－ルシフェリン誘導体、並びにこれら化合物の前駆体、並びにこれらの製造方法 |
-
1979
- 1979-07-18 DE DE19792929115 patent/DE2929115A1/de not_active Withdrawn
-
1980
- 1980-06-19 IL IL60362A patent/IL60362A/xx unknown
- 1980-06-20 SU SU802937845A patent/SU1055332A3/ru active
- 1980-07-14 EP EP80104081A patent/EP0024525B1/de not_active Expired
- 1980-07-14 AT AT80104081T patent/ATE1287T1/de active
- 1980-07-14 DE DE8080104081T patent/DE3060623D1/de not_active Expired
- 1980-07-16 JP JP9629280A patent/JPS5616480A/ja active Granted
-
1987
- 1987-09-10 US US07/095,122 patent/US4826989A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE1287T1 (de) | 1982-07-15 |
| IL60362A0 (en) | 1980-09-16 |
| US4826989A (en) | 1989-05-02 |
| EP0024525B1 (de) | 1982-06-30 |
| DE3060623D1 (en) | 1982-08-19 |
| SU1055332A3 (ru) | 1983-11-15 |
| EP0024525A1 (de) | 1981-03-11 |
| DE2929115A1 (de) | 1981-02-12 |
| JPH0150704B2 (xx) | 1989-10-31 |
| JPS5616480A (en) | 1981-02-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3060623D1 (en) | Process for the preparation of luciferin and its derivatives | |
| FR2502153B1 (xx) | ||
| AU540421B2 (en) | Substituted 1,2,4-triazolyl methyl -tert-butyl carbinols | |
| ES445928A1 (es) | Procedimiento para la preparacion de compuestos de imidazo- linio cuaternarios. | |
| DE3060113D1 (en) | Process for the preparation of diaryl ethers | |
| DE3167774D1 (en) | 4-substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics | |
| ES8101550A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 2-pirrolidin-metanol. | |
| JPS57106695A (en) | Anthracycline g lycoside compound | |
| ES8400752A1 (es) | "procedimiento para la preparacion de nuevos derivados de ciclofosfamida". | |
| FR2421914A1 (fr) | 3-acetoxy-9b-11b-epoxy-pregna-trienes et dienes et procede de preparation de 6a-halogeno-pregna-1,4-diene-3 ones et de 6a halogeno-pregna-4-ene-3-ones correspondants | |
| DE3165993D1 (en) | Salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-(3.2.1)-octane-3-alkylcarboxylates, process for their preparation and therapeutic compositions containing them | |
| HUT34946A (en) | Process for the production of new 4-phenyl-4-oxo-2-butene carboxylic acid-derivatives | |
| FR2381733A1 (fr) | Procede de preparation de m-bromo-a,a,a-trifluorotoluenes | |
| DE3261515D1 (en) | Benzopyranyl ethers, process for their preparation and medicine containing those compounds and intermediates | |
| ES8303450A1 (es) | "procedimiento para la preparacion de 17a-alcohil-17b-hidroxi-1a-metil-4-androsten-3-onas". | |
| DE3260303D1 (en) | Process for the preparation of 4-quinolinones | |
| GR80658B (en) | Process for the preparation of 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine derivatives | |
| FR2498607B1 (xx) | ||
| DE3160968D1 (en) | Cardenolide-bis-digitoxoside derivatives, process for their preparation and their utilization as medicines | |
| ES8102110A1 (es) | Procedimiento para la preparacion de acido 1,2,3-tiadiazol- 5-il-tioglicolico | |
| DE3268984D1 (en) | Imidazolylcarboxylic acids, their derivatives and production | |
| JPS55379A (en) | Biss*2*44dinitrophenyl**methyllpyridinium compound*its manufacture and ph determinating agent containing it | |
| GB1545077A (en) | Process for purifying water using bis-isothiouronium salts | |
| IE821426L (en) | Production of ketoamines | |
| ZA839434B (en) | A process for preparing oxanosine and an intermediate used in this process |