ES8303450A1 - "procedimiento para la preparacion de 17a-alcohil-17b-hidroxi-1a-metil-4-androsten-3-onas". - Google Patents

"procedimiento para la preparacion de 17a-alcohil-17b-hidroxi-1a-metil-4-androsten-3-onas".

Info

Publication number
ES8303450A1
ES8303450A1 ES511253A ES511253A ES8303450A1 ES 8303450 A1 ES8303450 A1 ES 8303450A1 ES 511253 A ES511253 A ES 511253A ES 511253 A ES511253 A ES 511253A ES 8303450 A1 ES8303450 A1 ES 8303450A1
Authority
ES
Spain
Prior art keywords
alpha
androsten
methyl
preparation
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511253A
Other languages
English (en)
Other versions
ES511253A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES8303450A1 publication Critical patent/ES8303450A1/es
Publication of ES511253A0 publication Critical patent/ES511253A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

_(PROCEDIMIENTO PARA LA PREPARACION DE 17~C-ALCOHIL-17~J-HIDROXI-1~C-METIL-4-ANDROSTEN-3-ONAS . SE HACE REACCIONAR EL COMPUESTO DE FORMULA GENERAL (II) EN QUE X REPRESENTA UN GRUPO OXO, UN GRUPO OXIMINO, UN GRUPO ALCOXI CON 1 A 4 ATOMOS DE CARBONO Y UN ATOMO DE HIDROGENO O UN GRUPO ALCOHILENDIOXI CON 2 A 6 ATOMOS DE CARBONO, CON UN COMPUESTO ORGANOMETALICO RZ EN QUE Z REPRESENTA UN ION DE UN METAL ALCALINO O UN ION DE HALOGENURO DE MAGNESIO. SE OBTIENE EL COMPUESTO (I) EN QUE R REPRESENTA UN RADICAL ALCOHILO DE CADENA RECTA CON 3 A 8 ATOMOS DE CARBONO. ACTIVIDAD ANABOLICA.
ES511253A 1981-04-13 1982-04-07 "procedimiento para la preparacion de 17a-alcohil-17b-hidroxi-1a-metil-4-androsten-3-onas". Granted ES511253A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813115996 DE3115996A1 (de) 1981-04-13 1981-04-13 17(alpha)-alkyl-17(beta)-hydroxy-1(alpha)- methyl-4-androsten-3-one-.verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten

Publications (2)

Publication Number Publication Date
ES8303450A1 true ES8303450A1 (es) 1983-02-16
ES511253A0 ES511253A0 (es) 1983-02-16

Family

ID=6130599

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511253A Granted ES511253A0 (es) 1981-04-13 1982-04-07 "procedimiento para la preparacion de 17a-alcohil-17b-hidroxi-1a-metil-4-androsten-3-onas".

Country Status (10)

Country Link
US (1) US4673673A (es)
EP (1) EP0062903B1 (es)
JP (1) JPS57179197A (es)
AT (1) ATE22085T1 (es)
DE (2) DE3115996A1 (es)
DK (1) DK163519B (es)
ES (1) ES511253A0 (es)
GB (1) GB2098991A (es)
GR (1) GR75456B (es)
IE (1) IE53012B1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011543A1 (en) * 1988-05-25 1989-11-30 Hyman Edward S Detecting bacteria in urine of horses
US5616670A (en) * 1993-11-10 1997-04-01 Minnesota Mining And Manufacturing Company Pressure sensitive adhesives with good oily surface adhesion
US5602221A (en) * 1993-11-10 1997-02-11 Minnesota Mining And Manufacturing Company Pressure sensitive adhesives with good low energy surface adhesion
US5683798A (en) * 1993-11-10 1997-11-04 Minnesota Mining And Manufacturing Company Tackified pressure sensitive adhesives
US5654387A (en) * 1993-11-10 1997-08-05 Minnesota Mining And Manufacturing Company Pressure sensitive adhesives
US5620795A (en) * 1993-11-10 1997-04-15 Minnesota Mining And Manufacturing Company Adhesives containing electrically conductive agents
DE69519368T2 (de) * 1994-01-06 2001-03-08 Stanford Res Inst Int Neue antiandrogenen mitteln pharmazeutische präparate und verwendungen davon

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1223837B (de) * 1963-04-17 1966-09-01 Schering Ag Verfahren zur Herstellung von 1alpha-Methyl-delta 4-3-ketosteroiden
US3391168A (en) * 1965-08-23 1968-07-02 Searle & Co 1, 17-dimethyl-5-androstane-3beta, 17beta-diol and esters thereof
DE2046640C3 (de) * 1970-09-14 1973-10-18 Schering Ag Verfahren zur Herstellung von Delta hoch 4 -3-Oxo-l alpha-methyl·Steroiden
US3705180A (en) * 1971-09-02 1972-12-05 Paul D Klimstra 17-oxygenate-2-alpha-methyl-2-methylen-5 alpha-androstan-3-ones and intermediates
US4039669A (en) * 1975-08-01 1977-08-02 Sterling Drug Inc. Composition for topical application and use thereof
DE2943776A1 (de) * 1979-10-26 1981-05-14 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17 (alpha) -alkylsteroide, diese enthaltende praeparate sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DK164182A (da) 1982-10-14
EP0062903B1 (de) 1986-09-10
DE3273108D1 (en) 1986-10-16
IE820847L (en) 1982-10-13
DK163519B (da) 1992-03-09
JPS57179197A (en) 1982-11-04
JPH033677B2 (es) 1991-01-21
GR75456B (es) 1984-07-19
DE3115996A1 (de) 1982-11-04
GB2098991A (en) 1982-12-01
US4673673A (en) 1987-06-16
ATE22085T1 (de) 1986-09-15
ES511253A0 (es) 1983-02-16
EP0062903A1 (de) 1982-10-20
IE53012B1 (en) 1988-05-11

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303