DE2838895C2 - 5-Iminodaunomycin und dessen Salze - Google Patents

5-Iminodaunomycin und dessen Salze

Info

Publication number
DE2838895C2
DE2838895C2 DE2838895A DE2838895A DE2838895C2 DE 2838895 C2 DE2838895 C2 DE 2838895C2 DE 2838895 A DE2838895 A DE 2838895A DE 2838895 A DE2838895 A DE 2838895A DE 2838895 C2 DE2838895 C2 DE 2838895C2
Authority
DE
Germany
Prior art keywords
acid
iminodaunomycin
salts
salt
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2838895A
Other languages
German (de)
English (en)
Other versions
DE2838895A1 (de
Inventor
David Weston Chapel Hill N.C. Henry
George Low Cupertino Calif. Tong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SRI International Inc
Original Assignee
SRI International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SRI International Inc filed Critical SRI International Inc
Publication of DE2838895A1 publication Critical patent/DE2838895A1/de
Application granted granted Critical
Publication of DE2838895C2 publication Critical patent/DE2838895C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE2838895A 1977-09-08 1978-09-06 5-Iminodaunomycin und dessen Salze Expired DE2838895C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/831,438 US4109076A (en) 1977-09-08 1977-09-08 5-iminodaunomycin

Publications (2)

Publication Number Publication Date
DE2838895A1 DE2838895A1 (de) 1979-03-22
DE2838895C2 true DE2838895C2 (de) 1986-04-17

Family

ID=25259058

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2838895A Expired DE2838895C2 (de) 1977-09-08 1978-09-06 5-Iminodaunomycin und dessen Salze

Country Status (7)

Country Link
US (1) US4109076A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5492950A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1110619A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2838895C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2402666A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2005256B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1106299B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4353894A (en) * 1980-10-27 1982-10-12 Sri International 5-Iminodoxorubicin
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
US4826964A (en) * 1982-07-20 1989-05-02 Sri International Bridged oxygen analogs of daunorubcin and doxorubicin
ZA834867B (en) * 1982-07-20 1984-03-28 Stanford Res Inst Int Derivatives of morpholinyl daunorubicin and morpholinyl doxorubicin and analogues thereof
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
GB8617742D0 (en) * 1986-07-21 1986-08-28 Erba Farmitalia 6-amino anthracyclines
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
US5196522A (en) * 1990-11-01 1993-03-23 Board Of Regents, The University Of Texas System Anthracycline analogues bearing latent alkylating substituents
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
IT7850986A0 (it) 1978-09-06
IT1106299B (it) 1985-11-11
DE2838895A1 (de) 1979-03-22
CA1110619A (en) 1981-10-13
GB2005256A (en) 1979-04-19
JPS5492950A (en) 1979-07-23
US4109076A (en) 1978-08-22
FR2402666A1 (fr) 1979-04-06
GB2005256B (en) 1982-02-03
JPS6259712B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-12-12
FR2402666B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-10-31

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: MUELLER, H., DIPL.-ING., PAT.-ANW., 8000 MUENCHEN

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee