DE2801417A1 - Neue 11beta-substituierte 1,3,5(10)- trienische steroidderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Neue 11beta-substituierte 1,3,5(10)- trienische steroidderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
DE2801417A1
DE2801417A1 DE19782801417 DE2801417A DE2801417A1 DE 2801417 A1 DE2801417 A1 DE 2801417A1 DE 19782801417 DE19782801417 DE 19782801417 DE 2801417 A DE2801417 A DE 2801417A DE 2801417 A1 DE2801417 A1 DE 2801417A1
Authority
DE
Germany
Prior art keywords
radical
formula
carbon atoms
compounds
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19782801417
Other languages
German (de)
English (en)
Other versions
DE2801417C2 (US20110009641A1-20110113-C00116.png
Inventor
Daniel Philibert
Jean Georges Teutsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of DE2801417A1 publication Critical patent/DE2801417A1/de
Application granted granted Critical
Publication of DE2801417C2 publication Critical patent/DE2801417C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19782801417 1977-01-13 1978-01-13 Neue 11beta-substituierte 1,3,5(10)- trienische steroidderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen Granted DE2801417A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7700859A FR2377419A1 (fr) 1977-01-13 1977-01-13 Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
DE2801417A1 true DE2801417A1 (de) 1978-07-20
DE2801417C2 DE2801417C2 (US20110009641A1-20110113-C00116.png) 1992-09-17

Family

ID=9185438

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782801417 Granted DE2801417A1 (de) 1977-01-13 1978-01-13 Neue 11beta-substituierte 1,3,5(10)- trienische steroidderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (14)

Country Link
US (1) US4272530A (US20110009641A1-20110113-C00116.png)
JP (1) JPS5390254A (US20110009641A1-20110113-C00116.png)
BE (1) BE862870A (US20110009641A1-20110113-C00116.png)
CA (1) CA1121339A (US20110009641A1-20110113-C00116.png)
CH (1) CH630646A5 (US20110009641A1-20110113-C00116.png)
DE (1) DE2801417A1 (US20110009641A1-20110113-C00116.png)
DK (1) DK161334C (US20110009641A1-20110113-C00116.png)
FR (1) FR2377419A1 (US20110009641A1-20110113-C00116.png)
GB (1) GB1595133A (US20110009641A1-20110113-C00116.png)
HU (1) HU176154B (US20110009641A1-20110113-C00116.png)
IE (1) IE46302B1 (US20110009641A1-20110113-C00116.png)
LU (1) LU78859A1 (US20110009641A1-20110113-C00116.png)
NL (1) NL7800364A (US20110009641A1-20110113-C00116.png)
SE (1) SE435516B (US20110009641A1-20110113-C00116.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814327A (en) * 1986-07-25 1989-03-21 Schering Aktiengesellschaft 11 β-(4-isopropenylphenyl)estra-4,9-dienes, their production, and pharmaceutical preparations containing same
DE3925179A1 (de) * 1988-08-22 1990-03-08 Volkswagen Ag Verfahren zum betreiben einer brennkraftmaschine mit leerlaufdrehzahlregelung

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7701384A (nl) * 1977-02-10 1978-08-14 Akzo Nv Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.
FR2528434B1 (fr) 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
FR2640977A2 (en) * 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
DE4018168A1 (de) * 1990-06-01 1991-12-05 Schering Ag Ausgangsverbindungen fuer die herstellung von 10ss-h-steroiden und ein verfahren zur herstellung dieser ausgangsverbindungen
DE4132182A1 (de) * 1991-09-24 1993-03-25 Schering Ag 11(beta)-substituierte 14, 17-ethanoestratriene, verfahren zur herstellung dieser verbindungen, sowie ihre verwendung zur herstellung von arzneimitteln
US5427766A (en) * 1993-11-15 1995-06-27 The Dow Chemical Company Radiolabeled steroids for use in radiochemical-guided surgery
SK882003A3 (en) 2000-07-28 2003-07-01 Akzo Nobel Nv 16alpha-substituted steroid compounds, pharmaceutical composition comprising same and their use
FR2826004B1 (fr) * 2001-06-13 2008-03-28 Aventis Pharma Sa Procede de preparation de derives estrogenes
SI1624878T1 (sl) * 2003-05-22 2007-02-28 Pantarhei Bioscience Bv Uporaba sestavkov, ki obsegajo estrogensko komponento, za zdravljenje in preprecevanje muskuloskeletne bolecine
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
EP4231334A1 (en) 2020-10-15 2023-08-23 Resonac Corporation Etching gas, method for producing same, etching method, and method for producing semiconductor element
EP4231333A1 (en) 2020-10-15 2023-08-23 Resonac Corporation Etching gas, method for producing same, etching method, and method for producing semiconductor element

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299108A (en) * 1965-10-18 1967-01-17 Searle & Co 17alpha-alkynyl/alkenyl-13beta-alkyl-11-alkylgona-1, 3, 5 (10)-triene-3, 17beta-diols, ethers and esters thereof and intermediates thereto
US3337365A (en) * 1963-03-25 1967-08-22 Ibm Electrical resistance composition and method of using the same to form a resistor
DE2029569A1 (de) * 1969-06-16 1971-02-11 GD Searle & Co , Skokie, 111 (V St A) Neue Steroide, Verfahren zu ihrer Her stellung sowie ihre Verwendung zur Bekämpfung von schädlichen Tieren
DE2361120A1 (de) * 1972-12-09 1974-06-12 Akzo Nv 11,11-alkylidensteroide und verfahren zu ihrer herstellung
DE2429040A1 (de) * 1973-06-18 1975-01-09 Roussel Uclaf Steroid-haptene, verfahren zu deren herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3346602A (en) * 1966-10-12 1967-10-10 Searle & Co 13beta-alkyl-11-alkylgona-1, 3, 5 (10)-trien-17-ones, ethers and esters thereof
US3465010A (en) * 1966-11-22 1969-09-02 Searle & Co 17 - (unsaturated hydrocarbon - substituted) 11,13beta - dialkylgon -4 - ene - 3,17beta-diols and esters thereof
GB1255345A (en) * 1969-08-15 1971-12-01 Searle & Co 3-(3-OXO-11beta13beta-DIALKYL-17beta-HYDROXYGON-4-EN-17alpha-YL) PROPIONIC ACID gamma-LACTONE
US3755301A (en) * 1972-06-23 1973-08-28 Searle & Co Manufacture of 11-alkyl steroids
NL7317358A (nl) * 1973-12-19 1975-06-23 Akzo Nv Nieuwe 11(beta)-alkylsteroiden van de oestraanreeks.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3337365A (en) * 1963-03-25 1967-08-22 Ibm Electrical resistance composition and method of using the same to form a resistor
US3299108A (en) * 1965-10-18 1967-01-17 Searle & Co 17alpha-alkynyl/alkenyl-13beta-alkyl-11-alkylgona-1, 3, 5 (10)-triene-3, 17beta-diols, ethers and esters thereof and intermediates thereto
DE2029569A1 (de) * 1969-06-16 1971-02-11 GD Searle & Co , Skokie, 111 (V St A) Neue Steroide, Verfahren zu ihrer Her stellung sowie ihre Verwendung zur Bekämpfung von schädlichen Tieren
DE2361120A1 (de) * 1972-12-09 1974-06-12 Akzo Nv 11,11-alkylidensteroide und verfahren zu ihrer herstellung
DE2429040A1 (de) * 1973-06-18 1975-01-09 Roussel Uclaf Steroid-haptene, verfahren zu deren herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Steroids, Vol. 37, 1981, S. 361-382 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814327A (en) * 1986-07-25 1989-03-21 Schering Aktiengesellschaft 11 β-(4-isopropenylphenyl)estra-4,9-dienes, their production, and pharmaceutical preparations containing same
US5089488A (en) * 1986-07-25 1992-02-18 Schering Aktiengesellschaft β-(4-isopropenylphenyl)estra-4,9-dienes, their production, and pharmaceutical preparations containing same
DE3925179A1 (de) * 1988-08-22 1990-03-08 Volkswagen Ag Verfahren zum betreiben einer brennkraftmaschine mit leerlaufdrehzahlregelung

Also Published As

Publication number Publication date
JPS6257638B2 (US20110009641A1-20110113-C00116.png) 1987-12-02
DK161334C (da) 1991-12-09
IE780079L (en) 1978-07-13
NL7800364A (nl) 1978-07-17
LU78859A1 (fr) 1978-09-18
GB1595133A (en) 1981-08-05
CH630646A5 (fr) 1982-06-30
US4272530A (en) 1981-06-09
CA1121339A (fr) 1982-04-06
IE46302B1 (en) 1983-04-20
DE2801417C2 (US20110009641A1-20110113-C00116.png) 1992-09-17
JPS5390254A (en) 1978-08-08
FR2377419A1 (fr) 1978-08-11
SE435516B (sv) 1984-10-01
FR2377419B1 (US20110009641A1-20110113-C00116.png) 1979-04-20
HU176154B (en) 1980-12-28
SE7714614L (sv) 1978-07-14
DK13978A (da) 1978-07-14
BE862870A (fr) 1978-07-12
DK161334B (da) 1991-06-24

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Legal Events

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8110 Request for examination paragraph 44
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Representative=s name: ZUMSTEIN SEN., F., DR. ASSMANN, E., DIPL.-CHEM. DR

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8125 Change of the main classification

Ipc: A61K 31/19

D2 Grant after examination
8380 Miscellaneous part iii

Free format text: SEITE 5, ZEILE 49 "ALKYLREST" AENDERN IN "ALLYLREST"

8325 Change of the main classification

Ipc: C07J 1/00

8380 Miscellaneous part iii

Free format text: DIE NEBENKLASSEN LAUTEN RICHTIG: "C07J 17/00 C07J 33/00 A61K 31/575"

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee