DE2753140C2 - Arzneimittel zur Behandlung von Magengeschwüren - Google Patents
Arzneimittel zur Behandlung von MagengeschwürenInfo
- Publication number
- DE2753140C2 DE2753140C2 DE2753140A DE2753140A DE2753140C2 DE 2753140 C2 DE2753140 C2 DE 2753140C2 DE 2753140 A DE2753140 A DE 2753140A DE 2753140 A DE2753140 A DE 2753140A DE 2753140 C2 DE2753140 C2 DE 2753140C2
- Authority
- DE
- Germany
- Prior art keywords
- iron
- cdi
- sulfate
- ulcers
- healing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 title claims description 14
- 208000007107 Stomach Ulcer Diseases 0.000 title claims description 11
- 229940079593 drug Drugs 0.000 title claims description 9
- 230000035876 healing Effects 0.000 claims description 12
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 9
- 208000025865 Ulcer Diseases 0.000 claims description 8
- 231100000397 ulcer Toxicity 0.000 claims description 8
- 239000009517 FM 100 Substances 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 5
- 241000700159 Rattus Species 0.000 claims description 4
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 3
- 201000005917 gastric ulcer Diseases 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims 7
- 244000223014 Syzygium aromaticum Species 0.000 claims 7
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims 6
- 208000028235 central diabetes insipidus Diseases 0.000 claims 6
- 244000303040 Glycyrrhiza glabra Species 0.000 claims 5
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 claims 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 4
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims 4
- 235000011477 liquorice Nutrition 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- 229910000359 iron(II) sulfate Inorganic materials 0.000 claims 3
- 210000002784 stomach Anatomy 0.000 claims 3
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims 2
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims 2
- 238000002474 experimental method Methods 0.000 claims 2
- 229910052742 iron Inorganic materials 0.000 claims 2
- 229940010454 licorice Drugs 0.000 claims 2
- 230000002195 synergetic effect Effects 0.000 claims 2
- 206010002091 Anaesthesia Diseases 0.000 claims 1
- BQENDLAVTKRQMS-SBBGFIFASA-L Carbenoxolone sodium Chemical compound [Na+].[Na+].C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C([O-])=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](OC(=O)CCC([O-])=O)C1(C)C BQENDLAVTKRQMS-SBBGFIFASA-L 0.000 claims 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- 229920002261 Corn starch Polymers 0.000 claims 1
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 claims 1
- 241000202807 Glycyrrhiza Species 0.000 claims 1
- 206010022971 Iron Deficiencies Diseases 0.000 claims 1
- 241000700157 Rattus norvegicus Species 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- HOBWAPHTEJGALG-JKCMADFCSA-N [(1r,5s)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate;sulfate Chemical compound [O-]S([O-])(=O)=O.C([C@H]1CC[C@@H](C2)[NH+]1C)C2OC(=O)C(CO)C1=CC=CC=C1.C([C@H]1CC[C@@H](C2)[NH+]1C)C2OC(=O)C(CO)C1=CC=CC=C1 HOBWAPHTEJGALG-JKCMADFCSA-N 0.000 claims 1
- 210000000683 abdominal cavity Anatomy 0.000 claims 1
- 230000037005 anaesthesia Effects 0.000 claims 1
- 229940069428 antacid Drugs 0.000 claims 1
- 239000003159 antacid agent Substances 0.000 claims 1
- 230000001078 anti-cholinergic effect Effects 0.000 claims 1
- 229960002028 atropine sulfate Drugs 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 229960000530 carbenoxolone Drugs 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 1
- 230000002026 carminative effect Effects 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 239000000812 cholinergic antagonist Substances 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003172 expectorant agent Substances 0.000 claims 1
- 230000003419 expectorant effect Effects 0.000 claims 1
- 239000000284 extract Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 230000000762 glandular Effects 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000008141 laxative Substances 0.000 claims 1
- 230000002475 laxative effect Effects 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000004400 mucous membrane Anatomy 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 238000005728 strengthening Methods 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 235000018553 tannin Nutrition 0.000 claims 1
- 229920001864 tannin Polymers 0.000 claims 1
- 239000001648 tannin Substances 0.000 claims 1
- 238000010998 test method Methods 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB49885/76A GB1548738A (en) | 1976-11-30 | 1976-11-30 | Antipeptic ulcer composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2753140A1 DE2753140A1 (de) | 1978-06-01 |
| DE2753140C2 true DE2753140C2 (de) | 1985-01-03 |
Family
ID=10453894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2753140A Expired DE2753140C2 (de) | 1976-11-30 | 1977-11-29 | Arzneimittel zur Behandlung von Magengeschwüren |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4544551A (enExample) |
| DE (1) | DE2753140C2 (enExample) |
| FR (1) | FR2373286A1 (enExample) |
| GB (1) | GB1548738A (enExample) |
| HK (1) | HK47880A (enExample) |
| MY (1) | MY8100157A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60326179D1 (de) * | 2003-10-28 | 2009-03-26 | Council Scient Ind Res | Pflanzliche zubereitung zur behandlung von magengeschwüren |
| CN107875197A (zh) * | 2016-09-30 | 2018-04-06 | 深圳市傲来大健康产业有限公司 | 一种组合物及其制备方法和用途 |
-
1976
- 1976-11-30 GB GB49885/76A patent/GB1548738A/en not_active Expired
-
1977
- 1977-11-29 DE DE2753140A patent/DE2753140C2/de not_active Expired
- 1977-11-29 FR FR7735877A patent/FR2373286A1/fr active Granted
-
1980
- 1980-08-28 HK HK478/80A patent/HK47880A/xx unknown
-
1981
- 1981-12-30 MY MY157/81A patent/MY8100157A/xx unknown
-
1982
- 1982-02-22 US US06/350,865 patent/US4544551A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2373286A1 (fr) | 1978-07-07 |
| DE2753140A1 (de) | 1978-06-01 |
| FR2373286B1 (enExample) | 1980-10-17 |
| MY8100157A (en) | 1981-12-31 |
| US4544551A (en) | 1985-10-01 |
| HK47880A (en) | 1980-09-05 |
| GB1548738A (en) | 1979-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OAP | Request for examination filed | ||
| OD | Request for examination | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8320 | Willingness to grant licences declared (paragraph 23) | ||
| 8339 | Ceased/non-payment of the annual fee |