DE2715803A1 - Peptidderivate - Google Patents

Peptidderivate

Info

Publication number
DE2715803A1
DE2715803A1 DE19772715803 DE2715803A DE2715803A1 DE 2715803 A1 DE2715803 A1 DE 2715803A1 DE 19772715803 DE19772715803 DE 19772715803 DE 2715803 A DE2715803 A DE 2715803A DE 2715803 A1 DE2715803 A1 DE 2715803A1
Authority
DE
Germany
Prior art keywords
radical
gly
carbon atoms
lys
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19772715803
Other languages
German (de)
English (en)
Inventor
Anand Swaroop Dutta
James Joseph Gormley
Christopher Frederick Hayward
John Selwyn Morley
Gilbert Joseph Stacey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB14362/76A external-priority patent/GB1523812A/en
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of DE2715803A1 publication Critical patent/DE2715803A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE19772715803 1976-04-08 1977-04-07 Peptidderivate Withdrawn DE2715803A1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB14362/76A GB1523812A (en) 1976-04-08 1976-04-08 Polypeptide
GB2106376 1976-05-21
GB2205576 1976-05-27
GB2929876 1976-07-14
GB4483776 1976-10-28
GB4483876 1976-10-28

Publications (1)

Publication Number Publication Date
DE2715803A1 true DE2715803A1 (de) 1977-10-27

Family

ID=27546664

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772715803 Withdrawn DE2715803A1 (de) 1976-04-08 1977-04-07 Peptidderivate

Country Status (13)

Country Link
JP (1) JPS52139039A (enExample)
AU (1) AU510760B2 (enExample)
CS (1) CS202568B2 (enExample)
DD (1) DD130348A5 (enExample)
DE (1) DE2715803A1 (enExample)
DK (1) DK158077A (enExample)
FI (1) FI771049A7 (enExample)
FR (1) FR2347336A1 (enExample)
HU (1) HU176260B (enExample)
NZ (1) NZ183712A (enExample)
PL (1) PL106210B1 (enExample)
SE (1) SE7704043L (enExample)
SU (1) SU904518A3 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740699A1 (de) * 1976-09-16 1978-03-23 Richter Gedeon Vegyeszet Pentapeptide, solche enthaltende arzneimittel sowie verfahren zur herstellung derselben
EP0024664A1 (de) * 1979-08-22 1981-03-11 Hoechst Aktiengesellschaft Neue Peptidamide und Verfahren zu ihrer Herstellung
WO2004106289A1 (en) * 2003-05-30 2004-12-09 Prozymex A/S Protease inhibitors
WO2012107244A1 (en) * 2011-02-09 2012-08-16 Organobalance Gmbh Peptide for use in the treatment of skin conditions

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2730851A1 (de) * 1976-07-19 1978-01-26 Sandoz Ag Neu polypeptidderivate, ihre herstellung und verwendung
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
NO773013L (no) * 1976-09-01 1978-03-02 David Howard Coy Fremgangsmaate ved fremstilling av methionin-enkefalin-derivater
US4259234A (en) * 1976-09-27 1981-03-31 Eli Lilly And Company Analgesic compounds
DE2752341A1 (de) * 1976-11-23 1978-05-24 Wellcome Found Biologisch wirksame amide, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische formulierungen
GB1604850A (en) * 1977-11-24 1981-12-16 Wellcome Found Biologically active peptides
DE2862327D1 (en) * 1977-07-22 1983-11-10 Wellcome Found Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them
US4178371A (en) * 1977-12-15 1979-12-11 Reckitt & Colman Products Limited Tetrapeptide derivatives
FR2424253A1 (fr) * 1978-04-27 1979-11-23 Brun Lab Sa Le Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique
US4278596A (en) * 1978-08-08 1981-07-14 American Home Products Corporation Analgesic pentapeptides
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
JPS5692846A (en) * 1979-12-27 1981-07-27 Takeda Chem Ind Ltd Tetrapeptide derivative and its preparation
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
US4495178A (en) * 1983-10-06 1985-01-22 G. D. Searle & Co. Enkephalin analogs
JP2604268B2 (ja) * 1990-04-09 1997-04-30 富士写真フイルム株式会社 ペプチド誘導体両親媒性化合物、その中間体、ペプチド誘導体両親媒性化合物を用いたリポソームおよび薄膜
JP2013043885A (ja) * 2011-08-26 2013-03-04 Kansai Bunri Sogo Gakuen デヒドロアミノ酸含有グリセロール誘導体
CZ2012313A3 (cs) * 2012-05-11 2013-05-29 Zetor Tractors A.S. Usporádání reverzacní dvoutoké prevodovky, zejména pro motorová vozidla a stavební stroje, s dvema vetvemi toku výkonu
US12037416B2 (en) * 2017-11-17 2024-07-16 Cytogel Pharma, Llc Polymer agonists of mu opioid receptors

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
"Amino-acids, Peptides and Proteins" (periodische Spezialistenberichte), The Chemical Society, London, Bd. 1 bis 8
Eddy and Leimbach, J. Pharmac. Exp. Therap., 1953, 107, 385-393
F.M. Finn und K. Kaufmann, "The Proteins", Bd. II, hrsg. von H. Neurath und R.L. Hill, Academic Press Inc., New York, 1976, S. 106
J.R. McDermott und N.L. Benoiton in Can. J. Chem., 1973, 51, 1915
Kosterlitz et al. in Nature, 1975, 258, 577 bis 579
M. Bodansky und M.A. Ondetti, "Peptide Synthesis", Interscience, New York, 1966, Kapitel IV
Pure and Applied Chemistry, 1974, 40, 317-331

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740699A1 (de) * 1976-09-16 1978-03-23 Richter Gedeon Vegyeszet Pentapeptide, solche enthaltende arzneimittel sowie verfahren zur herstellung derselben
EP0024664A1 (de) * 1979-08-22 1981-03-11 Hoechst Aktiengesellschaft Neue Peptidamide und Verfahren zu ihrer Herstellung
US4459225A (en) * 1979-08-22 1984-07-10 Hoechst Aktiengesellschaft Peptide amides and process for their manufacture
WO2004106289A1 (en) * 2003-05-30 2004-12-09 Prozymex A/S Protease inhibitors
EP1975153A3 (en) * 2003-05-30 2010-03-31 Prozymex A/S Protease inhibitors
WO2012107244A1 (en) * 2011-02-09 2012-08-16 Organobalance Gmbh Peptide for use in the treatment of skin conditions

Also Published As

Publication number Publication date
JPS52139039A (en) 1977-11-19
CS202568B2 (en) 1981-01-30
AU2381977A (en) 1978-10-05
FR2347336A1 (fr) 1977-11-04
NZ183712A (en) 1979-10-25
DD130348A5 (de) 1978-03-22
HU176260B (en) 1981-01-28
SU904518A3 (ru) 1982-02-07
PL106210B1 (pl) 1979-12-31
FR2347336B1 (enExample) 1980-07-18
SE7704043L (sv) 1977-10-09
AU510760B2 (en) 1980-07-10
FI771049A7 (enExample) 1977-10-09
PL197302A1 (pl) 1978-02-13
DK158077A (da) 1977-10-09

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination