DE2625471A1 - Polyurethanschaum mit in ihm gebundenem biologischen material und verfahren zu seiner herstellung - Google Patents
Polyurethanschaum mit in ihm gebundenem biologischen material und verfahren zu seiner herstellungInfo
- Publication number
- DE2625471A1 DE2625471A1 DE19762625471 DE2625471A DE2625471A1 DE 2625471 A1 DE2625471 A1 DE 2625471A1 DE 19762625471 DE19762625471 DE 19762625471 DE 2625471 A DE2625471 A DE 2625471A DE 2625471 A1 DE2625471 A1 DE 2625471A1
- Authority
- DE
- Germany
- Prior art keywords
- enzyme
- coenzyme
- dehydrogenase
- biological material
- adenine dinucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012620 biological material Substances 0.000 title claims description 15
- 229920005830 Polyurethane Foam Polymers 0.000 title claims description 13
- 239000011496 polyurethane foam Substances 0.000 title claims description 13
- 238000000034 method Methods 0.000 title claims description 6
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- 102000004190 Enzymes Human genes 0.000 claims description 25
- 108090000790 Enzymes Proteins 0.000 claims description 25
- 239000005515 coenzyme Substances 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 12
- 229920005862 polyol Polymers 0.000 claims description 12
- 150000003077 polyols Chemical class 0.000 claims description 12
- 101710088194 Dehydrogenase Proteins 0.000 claims description 11
- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 claims description 11
- 229960001456 adenosine triphosphate Drugs 0.000 claims description 10
- ZJCCRDAZUWHFQH-UHFFFAOYSA-N Trimethylolpropane Chemical compound CCC(CO)(CO)CO ZJCCRDAZUWHFQH-UHFFFAOYSA-N 0.000 claims description 8
- 239000002202 Polyethylene glycol Substances 0.000 claims description 7
- 239000006260 foam Substances 0.000 claims description 7
- 229920001223 polyethylene glycol Polymers 0.000 claims description 7
- -1 polyoxyethylene Polymers 0.000 claims description 6
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- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 claims description 4
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- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 4
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- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 claims description 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 4
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- 239000011678 thiamine pyrophosphate Substances 0.000 claims description 4
- YXVCLPJQTZXJLH-UHFFFAOYSA-N thiamine(1+) diphosphate chloride Chemical compound [Cl-].CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N YXVCLPJQTZXJLH-UHFFFAOYSA-N 0.000 claims description 4
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- 108090000364 Ligases Proteins 0.000 claims description 3
- 102000003960 Ligases Human genes 0.000 claims description 3
- QIAFMBKCNZACKA-UHFFFAOYSA-N N-benzoylglycine Chemical compound OC(=O)CNC(=O)C1=CC=CC=C1 QIAFMBKCNZACKA-UHFFFAOYSA-N 0.000 claims description 3
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- ODBLHEXUDAPZAU-ZAFYKAAXSA-N D-threo-isocitric acid Chemical compound OC(=O)[C@H](O)[C@@H](C(O)=O)CC(O)=O ODBLHEXUDAPZAU-ZAFYKAAXSA-N 0.000 claims description 2
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- 108010004237 Glycine oxidase Proteins 0.000 claims description 2
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- 108090000913 Nitrate Reductases Proteins 0.000 claims description 2
- 102000004459 Nitroreductase Human genes 0.000 claims description 2
- 229910019142 PO4 Inorganic materials 0.000 claims description 2
- 102000003992 Peroxidases Human genes 0.000 claims description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 2
- 102100033055 Transketolase Human genes 0.000 claims description 2
- 108010043652 Transketolase Proteins 0.000 claims description 2
- 102100033220 Xanthine oxidase Human genes 0.000 claims description 2
- 108010093894 Xanthine oxidase Proteins 0.000 claims description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 2
- 229960000723 ampicillin Drugs 0.000 claims description 2
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- 229960003071 bacitracin Drugs 0.000 claims description 2
- 229930184125 bacitracin Natural products 0.000 claims description 2
- CLKOFPXJLQSYAH-ABRJDSQDSA-N bacitracin A Chemical compound C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2N=CNC=2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 0.000 claims description 2
- 230000003115 biocidal effect Effects 0.000 claims description 2
- 229960003346 colistin Drugs 0.000 claims description 2
- 125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 claims description 2
- 108010004872 glycocyamine phosphokinase Proteins 0.000 claims description 2
- 108010062584 glycollate oxidase Proteins 0.000 claims description 2
- 239000004310 lactic acid Substances 0.000 claims description 2
- 235000014655 lactic acid Nutrition 0.000 claims description 2
- 239000001630 malic acid Substances 0.000 claims description 2
- 235000011090 malic acid Nutrition 0.000 claims description 2
- JORAUNFTUVJTNG-BSTBCYLQSA-N n-[(2s)-4-amino-1-[[(2s,3r)-1-[[(2s)-4-amino-1-oxo-1-[[(3s,6s,9s,12s,15r,18s,21s)-6,9,18-tris(2-aminoethyl)-3-[(1r)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-h Chemical compound CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O.CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O JORAUNFTUVJTNG-BSTBCYLQSA-N 0.000 claims description 2
- 229960004927 neomycin Drugs 0.000 claims description 2
- 108020001162 nitroreductase Proteins 0.000 claims description 2
- 108040007629 peroxidase activity proteins Proteins 0.000 claims description 2
- 239000010452 phosphate Substances 0.000 claims description 2
- XDJYMJULXQKGMM-UHFFFAOYSA-N polymyxin E1 Natural products CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O XDJYMJULXQKGMM-UHFFFAOYSA-N 0.000 claims description 2
- KNIWPHSUTGNZST-UHFFFAOYSA-N polymyxin E2 Natural products CC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O KNIWPHSUTGNZST-UHFFFAOYSA-N 0.000 claims description 2
- 239000001384 succinic acid Substances 0.000 claims description 2
- ODBLHEXUDAPZAU-UHFFFAOYSA-N threo-D-isocitric acid Natural products OC(=O)C(O)C(C(O)=O)CC(O)=O ODBLHEXUDAPZAU-UHFFFAOYSA-N 0.000 claims description 2
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 claims 2
- 102100031126 6-phosphogluconolactonase Human genes 0.000 claims 1
- 108010029731 6-phosphogluconolactonase Proteins 0.000 claims 1
- MNQZXJOMYWMBOU-VKHMYHEASA-N D-glyceraldehyde Chemical compound OC[C@@H](O)C=O MNQZXJOMYWMBOU-VKHMYHEASA-N 0.000 claims 1
- 108010018962 Glucosephosphate Dehydrogenase Proteins 0.000 claims 1
- 102000000587 Glycerolphosphate Dehydrogenase Human genes 0.000 claims 1
- 108010041921 Glycerolphosphate Dehydrogenase Proteins 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- ZKHQWZAMYRWXGA-KQYNXXCUSA-N Adenosine triphosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-N 0.000 description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
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- 239000002904 solvent Substances 0.000 description 2
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- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
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- 108010046334 Urease Proteins 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 description 1
- 125000002723 alicyclic group Chemical group 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
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- 102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 description 1
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
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- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
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- RUELTTOHQODFPA-UHFFFAOYSA-N toluene 2,6-diisocyanate Chemical compound CC1=C(N=C=O)C=CC=C1N=C=O RUELTTOHQODFPA-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K11/00—Fructose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/098—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer formed in the presence of the enzymes or microbial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/44—Antibodies bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6415—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63 having nitrogen
- C08G18/6446—Proteins and derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/093—Polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K1/00—Glucose; Glucose-containing syrups
- C13K1/06—Glucose; Glucose-containing syrups obtained by saccharification of starch or raw materials containing starch
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Polymers & Plastics (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Polyurethanes Or Polyureas (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Materials For Medical Uses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58567475A | 1975-06-10 | 1975-06-10 | |
| US64402575A | 1975-12-24 | 1975-12-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2625471A1 true DE2625471A1 (de) | 1976-12-23 |
| DE2625471C2 DE2625471C2 (enrdf_load_stackoverflow) | 1990-03-01 |
Family
ID=27079466
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19762625471 Granted DE2625471A1 (de) | 1975-06-10 | 1976-06-05 | Polyurethanschaum mit in ihm gebundenem biologischen material und verfahren zu seiner herstellung |
| DE2625544A Expired DE2625544C2 (de) | 1975-06-10 | 1976-06-05 | Verfahren zur Immobilisierung eines biologischen Materials und Zusammensetzung zur Durchführung des Verfahrens |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2625544A Expired DE2625544C2 (de) | 1975-06-10 | 1976-06-05 | Verfahren zur Immobilisierung eines biologischen Materials und Zusammensetzung zur Durchführung des Verfahrens |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS51148089A (enrdf_load_stackoverflow) |
| AT (1) | AT349628B (enrdf_load_stackoverflow) |
| CA (1) | CA1088008A (enrdf_load_stackoverflow) |
| CH (1) | CH634347A5 (enrdf_load_stackoverflow) |
| DE (2) | DE2625471A1 (enrdf_load_stackoverflow) |
| FR (2) | FR2314196B2 (enrdf_load_stackoverflow) |
| GB (2) | GB1518746A (enrdf_load_stackoverflow) |
| MX (1) | MX3442E (enrdf_load_stackoverflow) |
| NL (1) | NL7606211A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0019215A1 (de) * | 1979-05-21 | 1980-11-26 | Bayer Ag | Verfahren zur Herstellung denaturierter Polyadditionsprodukte aus Isocyanat-Destillationsrückständen und Biomassen, sowie deren Verwendung als reaktiver Füllstoff, als Pflanzennährstoff und als Bindemittel zur Herstellung von Platten oder Formteilen |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226935A (en) * | 1978-08-07 | 1980-10-07 | W. R. Grace & Co. | Enzymatic diagnostic composition |
| DE2920527A1 (de) | 1979-05-21 | 1981-02-05 | Bayer Ag | Verfahren zur herstellung von polyurethankunststoffen |
| DE2929872C2 (de) * | 1979-07-24 | 1985-10-31 | Joachim Prof. Dr. Klein | Verfahren zur Herstellung von hydrophilen, gelförmig oder geschäumten Biokatalysatoren mit hoher Beladung an enzymatisch aktiver Substanz |
| DE3222912A1 (de) * | 1982-06-18 | 1983-12-22 | Basf Ag, 6700 Ludwigshafen | Unloeslicher biokatalysator |
| US5049358A (en) * | 1988-09-30 | 1991-09-17 | Miles Inc. | Composition and test device for assaying for proteins |
| CA2001557A1 (en) * | 1988-12-19 | 1990-06-19 | Timothy M. Coryn | Test method and device for total protein assay |
| US7186813B1 (en) * | 2000-01-11 | 2007-03-06 | Nanogen Recognomics Gmbh | Biomolecules having multiple attachment moieties for binding to a substrate surface |
| US9828597B2 (en) | 2006-11-22 | 2017-11-28 | Toyota Motor Engineering & Manufacturing North America, Inc. | Biofunctional materials |
| EP2331688B1 (en) | 2008-09-30 | 2018-01-17 | Fresenius Medical Care Holdings, Inc. | Covalently immobilized enzyme and method to make the same |
| US11015149B2 (en) | 2010-06-21 | 2021-05-25 | Toyota Motor Corporation | Methods of facilitating removal of a fingerprint |
| US9388370B2 (en) | 2010-06-21 | 2016-07-12 | Toyota Motor Engineering & Manufacturing North America, Inc. | Thermolysin-like protease for cleaning insect body stains |
| US9121016B2 (en) | 2011-09-09 | 2015-09-01 | Toyota Motor Engineering & Manufacturing North America, Inc. | Coatings containing polymer modified enzyme for stable self-cleaning of organic stains |
| US8796009B2 (en) | 2010-06-21 | 2014-08-05 | Toyota Motor Engineering & Manufacturing North America, Inc. | Clearcoat containing thermolysin-like protease from Bacillus stearothermophilus for cleaning of insect body stains |
| US10988714B2 (en) | 2010-06-21 | 2021-04-27 | Regents Of The University Of Minnesota | Methods of facilitating removal of a fingerprint from a substrate or a coating |
| EP2541250A1 (en) * | 2011-06-30 | 2013-01-02 | Koninklijke Philips Electronics N.V. | Molecular architecture on magnetic particles for affinity assays with low non-specific binding |
| WO2016152702A1 (ja) * | 2015-03-24 | 2016-09-29 | 国立大学法人名古屋大学 | 分析デバイス |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1227855B (de) * | 1960-07-12 | 1966-11-03 | Ichthyol Ges | Verfahren zur Herstellung von Enzymkoerpern fuer die Durchfuehrung enzymatischer Reaktionen |
| DE1959169A1 (de) * | 1968-11-25 | 1970-06-04 | Nat Res Dev | Unloesliches enzymatisch reaktives Material |
| US3705084A (en) * | 1970-03-18 | 1972-12-05 | Monsanto Co | Macroporous enzyme reactor |
| US3672955A (en) * | 1970-05-20 | 1972-06-27 | Us Agriculture | Preparation of an insoluble active enzyme |
| DE2413137A1 (de) * | 1974-03-19 | 1975-10-16 | Boehringer Mannheim Gmbh | Enzymatisch aktiver schaumstoff und verfahren zu seiner herstellung |
| BE833191A (fr) * | 1975-09-01 | 1976-03-08 | Catalyseur pour une reaction biochimique et procede pour le preparer |
-
1976
- 1976-06-05 DE DE19762625471 patent/DE2625471A1/de active Granted
- 1976-06-05 DE DE2625544A patent/DE2625544C2/de not_active Expired
- 1976-06-08 CA CA254,273A patent/CA1088008A/en not_active Expired
- 1976-06-08 CH CH720076A patent/CH634347A5/de not_active IP Right Cessation
- 1976-06-09 FR FR7617451A patent/FR2314196B2/fr not_active Expired
- 1976-06-09 JP JP51066624A patent/JPS51148089A/ja active Pending
- 1976-06-09 GB GB23919/76A patent/GB1518746A/en not_active Expired
- 1976-06-09 NL NL7606211A patent/NL7606211A/xx not_active Application Discontinuation
- 1976-06-09 GB GB23937/76A patent/GB1517813A/en not_active Expired
- 1976-06-09 FR FR7617452A patent/FR2314195B1/fr not_active Expired
- 1976-06-09 AT AT420476A patent/AT349628B/de not_active IP Right Cessation
- 1976-06-09 MX MX100388U patent/MX3442E/es unknown
Non-Patent Citations (1)
| Title |
|---|
| NICHTS ERMITTELT * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0019215A1 (de) * | 1979-05-21 | 1980-11-26 | Bayer Ag | Verfahren zur Herstellung denaturierter Polyadditionsprodukte aus Isocyanat-Destillationsrückständen und Biomassen, sowie deren Verwendung als reaktiver Füllstoff, als Pflanzennährstoff und als Bindemittel zur Herstellung von Platten oder Formteilen |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS51148089A (en) | 1976-12-18 |
| FR2314195A1 (fr) | 1977-01-07 |
| NL7606211A (nl) | 1976-12-14 |
| FR2314195B1 (fr) | 1981-10-09 |
| FR2314196B2 (fr) | 1981-10-09 |
| GB1517813A (en) | 1978-07-12 |
| DE2625544A1 (de) | 1976-12-23 |
| CH634347A5 (en) | 1983-01-31 |
| GB1518746A (en) | 1978-07-26 |
| CA1088008A (en) | 1980-10-21 |
| MX3442E (es) | 1980-11-25 |
| AT349628B (de) | 1979-04-10 |
| ATA420476A (de) | 1978-09-15 |
| FR2314196A2 (fr) | 1977-01-07 |
| DE2625471C2 (enrdf_load_stackoverflow) | 1990-03-01 |
| DE2625544C2 (de) | 1986-09-11 |
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