GB1517813A - Carrier incorporating a biological material and process of preparing it - Google Patents

Carrier incorporating a biological material and process of preparing it

Info

Publication number
GB1517813A
GB1517813A GB23937/76A GB2393776A GB1517813A GB 1517813 A GB1517813 A GB 1517813A GB 23937/76 A GB23937/76 A GB 23937/76A GB 2393776 A GB2393776 A GB 2393776A GB 1517813 A GB1517813 A GB 1517813A
Authority
GB
United Kingdom
Prior art keywords
biological material
immobilise
proteins
primary
amino group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB23937/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WR Grace and Co
Original Assignee
WR Grace and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WR Grace and Co filed Critical WR Grace and Co
Publication of GB1517813A publication Critical patent/GB1517813A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K11/00—Fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/098—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer formed in the presence of the enzymes or microbial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
    • C08G18/6415—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63 having nitrogen
    • C08G18/6446—Proteins and derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/093—Polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K1/00—Glucose; Glucose-containing syrups
    • C13K1/06—Glucose; Glucose-containing syrups obtained by saccharification of starch or raw materials containing starch

Abstract

To immobilise a biologically active material, namely one or more of a) proteins, b) coenzymes having at least one primary or secondary amino group per molecule, c) enzymes, together with a coenzyme for the enzyme and d) antibiotics which are not proteins and contain at least one primary or secondary amino group per molecule, in solid articles, a process is used in which the biological material is intially incorporated into a liquid polyurethane prepolymer having terminal isocyanate groups. The mixture obtained is then reacted with an amount of a curing agent which is sufficient to immobilise the biologically active material under foam-forming or non-foam-forming conditions. The process is used for the preparation of self-supporting films, of films applied to supports, of discs or pellets of foamed polyurethane, or of a tube having an internal surface of polyurethane.
GB23937/76A 1975-06-10 1976-06-09 Carrier incorporating a biological material and process of preparing it Expired GB1517813A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58567475A 1975-06-10 1975-06-10
US64402575A 1975-12-24 1975-12-24

Publications (1)

Publication Number Publication Date
GB1517813A true GB1517813A (en) 1978-07-12

Family

ID=27079466

Family Applications (2)

Application Number Title Priority Date Filing Date
GB23919/76A Expired GB1518746A (en) 1975-06-10 1976-06-09 Process for producing an immobilized biological material
GB23937/76A Expired GB1517813A (en) 1975-06-10 1976-06-09 Carrier incorporating a biological material and process of preparing it

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB23919/76A Expired GB1518746A (en) 1975-06-10 1976-06-09 Process for producing an immobilized biological material

Country Status (9)

Country Link
JP (1) JPS51148089A (en)
AT (1) AT349628B (en)
CA (1) CA1088008A (en)
CH (1) CH634347A5 (en)
DE (2) DE2625471A1 (en)
FR (2) FR2314196B2 (en)
GB (2) GB1518746A (en)
MX (1) MX3442E (en)
NL (1) NL7606211A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320208A (en) 1979-05-21 1982-03-16 Bayer Aktiengesellschaft Process for the production of polyurethane plastics in which polyisocyanates are reacted with reactive organic fillers comprising biomasses
US4393166A (en) 1979-05-21 1983-07-12 Bayer Aktiengesellschaft Process for the preparation of polyaddition products of isocyanates and denatured biomasses, their use as reactive fillers and as plant nutrients and a process for the production of sheets or shaped articles using the polyaddition products
US4764467A (en) * 1982-06-18 1988-08-16 Basf Aktiengeselschaft, Preparation of an insoluble biocatalyst
US8497107B2 (en) 2008-09-30 2013-07-30 Fresenius Medical Care Holdings, Inc. Covalently immobilized enzyme and method to make the same

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226935A (en) * 1978-08-07 1980-10-07 W. R. Grace & Co. Enzymatic diagnostic composition
DE2929872C2 (en) * 1979-07-24 1985-10-31 Joachim Prof. Dr. Klein Process for the production of hydrophilic, gel-like or foamed biocatalysts with a high load of enzymatically active substance
US5049358A (en) * 1988-09-30 1991-09-17 Miles Inc. Composition and test device for assaying for proteins
CA2001557A1 (en) * 1988-12-19 1990-06-19 Timothy M. Coryn Test method and device for total protein assay
US9828597B2 (en) 2006-11-22 2017-11-28 Toyota Motor Engineering & Manufacturing North America, Inc. Biofunctional materials
US8796009B2 (en) 2010-06-21 2014-08-05 Toyota Motor Engineering & Manufacturing North America, Inc. Clearcoat containing thermolysin-like protease from Bacillus stearothermophilus for cleaning of insect body stains
US9121016B2 (en) 2011-09-09 2015-09-01 Toyota Motor Engineering & Manufacturing North America, Inc. Coatings containing polymer modified enzyme for stable self-cleaning of organic stains
US9388370B2 (en) 2010-06-21 2016-07-12 Toyota Motor Engineering & Manufacturing North America, Inc. Thermolysin-like protease for cleaning insect body stains
US10988714B2 (en) 2010-06-21 2021-04-27 Regents Of The University Of Minnesota Methods of facilitating removal of a fingerprint from a substrate or a coating
US11015149B2 (en) 2010-06-21 2021-05-25 Toyota Motor Corporation Methods of facilitating removal of a fingerprint
EP2541250A1 (en) * 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Molecular architecture on magnetic particles for affinity assays with low non-specific binding
JP6713601B2 (en) * 2015-03-24 2020-07-01 国立大学法人東海国立大学機構 Analysis device

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1227855B (en) * 1960-07-12 1966-11-03 Ichthyol Ges Process for the production of enzyme bodies for the implementation of enzymatic reactions
DE1959169A1 (en) * 1968-11-25 1970-06-04 Nat Res Dev Insoluble enzymatic reactive material
US3705084A (en) * 1970-03-18 1972-12-05 Monsanto Co Macroporous enzyme reactor
US3672955A (en) * 1970-05-20 1972-06-27 Us Agriculture Preparation of an insoluble active enzyme
DE2413137A1 (en) * 1974-03-19 1975-10-16 Boehringer Mannheim Gmbh Enzymatically active polyurethane foam - produced by adding conc. enzyme soln. to mix before forming, giving high activity
BE833191A (en) * 1975-09-01 1976-03-08 CATALYST FOR A BIOCHEMICAL REACTION AND PROCESS FOR PREPARING IT

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320208A (en) 1979-05-21 1982-03-16 Bayer Aktiengesellschaft Process for the production of polyurethane plastics in which polyisocyanates are reacted with reactive organic fillers comprising biomasses
US4393166A (en) 1979-05-21 1983-07-12 Bayer Aktiengesellschaft Process for the preparation of polyaddition products of isocyanates and denatured biomasses, their use as reactive fillers and as plant nutrients and a process for the production of sheets or shaped articles using the polyaddition products
US4454259A (en) * 1979-05-21 1984-06-12 Bayer Aktiengesellschaft Process for the preparation of polyaddition products of isocyanates and denatured biomasses, their use as reactive fillers and as plant nutrients and a process for the production of sheets or shaped articles using the polyaddition products
US4764467A (en) * 1982-06-18 1988-08-16 Basf Aktiengeselschaft, Preparation of an insoluble biocatalyst
US8497107B2 (en) 2008-09-30 2013-07-30 Fresenius Medical Care Holdings, Inc. Covalently immobilized enzyme and method to make the same
US9187744B2 (en) 2008-09-30 2015-11-17 Fresenius Medical Care Holdings, Inc. Covalently immobilized enzyme and method to make the same

Also Published As

Publication number Publication date
CA1088008A (en) 1980-10-21
DE2625471A1 (en) 1976-12-23
AT349628B (en) 1979-04-10
NL7606211A (en) 1976-12-14
DE2625544C2 (en) 1986-09-11
GB1518746A (en) 1978-07-26
FR2314196A2 (en) 1977-01-07
DE2625471C2 (en) 1990-03-01
FR2314196B2 (en) 1981-10-09
JPS51148089A (en) 1976-12-18
DE2625544A1 (en) 1976-12-23
MX3442E (en) 1980-11-25
ATA420476A (en) 1978-09-15
CH634347A5 (en) 1983-01-31
FR2314195B1 (en) 1981-10-09
FR2314195A1 (en) 1977-01-07

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)