DE2548087A1 - Antitumorglycoside und verfahren zu deren herstellung - Google Patents

Antitumorglycoside und verfahren zu deren herstellung

Info

Publication number
DE2548087A1
DE2548087A1 DE19752548087 DE2548087A DE2548087A1 DE 2548087 A1 DE2548087 A1 DE 2548087A1 DE 19752548087 DE19752548087 DE 19752548087 DE 2548087 A DE2548087 A DE 2548087A DE 2548087 A1 DE2548087 A1 DE 2548087A1
Authority
DE
Germany
Prior art keywords
epi
hydroxydaunomycin
nitrobenzoyl
solution
hydroxyadriamycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752548087
Other languages
German (de)
English (en)
Inventor
Federico Arcamone
Alberto Bargiotti
Guiseppe Cassinelli
Aurelio Di Marco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of DE2548087A1 publication Critical patent/DE2548087A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19752548087 1974-10-29 1975-10-28 Antitumorglycoside und verfahren zu deren herstellung Withdrawn DE2548087A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4664474A GB1470860A (en) 1974-10-29 1974-10-29 Anthracycline glycosides

Publications (1)

Publication Number Publication Date
DE2548087A1 true DE2548087A1 (de) 1976-05-06

Family

ID=10442049

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752548087 Withdrawn DE2548087A1 (de) 1974-10-29 1975-10-28 Antitumorglycoside und verfahren zu deren herstellung

Country Status (17)

Country Link
US (1) US4025623A (enExample)
JP (2) JPS5951559B2 (enExample)
AT (1) AT340591B (enExample)
AU (1) AU498511B2 (enExample)
BE (1) BE834939A (enExample)
CA (1) CA1046509A (enExample)
CH (2) CH618707A5 (enExample)
DE (1) DE2548087A1 (enExample)
DK (1) DK146803C (enExample)
ES (1) ES442144A1 (enExample)
FR (1) FR2289203A1 (enExample)
GB (1) GB1470860A (enExample)
NL (1) NL7512489A (enExample)
SE (1) SE423996B (enExample)
SU (2) SU646913A3 (enExample)
YU (2) YU37119B (enExample)
ZA (1) ZA756732B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169142A (en) * 1976-11-17 1979-09-25 Societa' Farmaceutici Italia S.P.A. Disaccharide analogs of antitumor anthracyclines, process for their preparation and use thereof

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1502121A (en) * 1975-08-02 1978-02-22 Farmaceutici Italia Anthracyclines
GB1524468A (en) * 1976-07-13 1978-09-13 Farmaceutici Italia Anthracylines
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
GB1573036A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
US4181795A (en) * 1978-05-22 1980-01-01 Purdue Research Foundation Daunosamine synthesis
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4303785A (en) * 1978-08-05 1981-12-01 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antitumor anthracycline antibiotics
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
JPS6130464U (ja) * 1984-07-26 1986-02-24 武夫 安田 食器洗い用具
JPH01207028A (ja) * 1987-02-09 1989-08-21 Tomiko Saito タワシと容器
JPH0261920U (enExample) * 1988-10-28 1990-05-09
JP3035035U (ja) * 1996-04-26 1997-03-11 裕敬 丸子 把手のあるスポンジ
EP1036797B1 (en) * 1997-12-05 2010-11-17 Mercian Corporation Crystalline anthracycline antibiotic and process for producing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
BE793976A (fr) * 1972-01-13 1973-05-02 Parke Davis & Co Nouvelles polyamines et procede pour les preparer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169142A (en) * 1976-11-17 1979-09-25 Societa' Farmaceutici Italia S.P.A. Disaccharide analogs of antitumor anthracyclines, process for their preparation and use thereof

Also Published As

Publication number Publication date
DK146803B (da) 1984-01-09
AU8604075A (en) 1977-05-05
DK482175A (da) 1976-04-30
FR2289203A1 (fr) 1976-05-28
CH618707A5 (enExample) 1980-08-15
JPS5951559B2 (ja) 1984-12-14
CA1046509A (en) 1979-01-16
SE423996B (sv) 1982-06-21
US4025623A (en) 1977-05-24
YU269575A (en) 1983-04-27
AT340591B (de) 1977-12-27
AU498511B2 (en) 1979-03-15
DK146803C (da) 1984-06-18
ZA756732B (en) 1976-10-27
SU628822A3 (ru) 1978-10-15
JPS6056720B2 (ja) 1985-12-11
SU646913A3 (ru) 1979-02-05
CH621799A5 (enExample) 1981-02-27
ATA812975A (de) 1977-04-15
ES442144A1 (es) 1977-08-01
BE834939A (fr) 1976-04-28
JPS5168561A (enExample) 1976-06-14
YU37119B (en) 1984-08-31
YU293381A (en) 1985-04-30
FR2289203B1 (enExample) 1978-11-10
NL7512489A (nl) 1976-05-04
SE7512005L (sv) 1976-04-30
GB1470860A (en) 1977-04-21
JPS59104397A (ja) 1984-06-16

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination