DE2500810A1 - Reinigen von plasminogen - Google Patents

Reinigen von plasminogen

Info

Publication number
DE2500810A1
DE2500810A1 DE19752500810 DE2500810A DE2500810A1 DE 2500810 A1 DE2500810 A1 DE 2500810A1 DE 19752500810 DE19752500810 DE 19752500810 DE 2500810 A DE2500810 A DE 2500810A DE 2500810 A1 DE2500810 A1 DE 2500810A1
Authority
DE
Germany
Prior art keywords
plasminogen
molar
solution
ammonium sulfate
streptokinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19752500810
Other languages
German (de)
English (en)
Inventor
William Wolcott Andres
William Homer Holleman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE2500810A1 publication Critical patent/DE2500810A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/816—Enzyme separation or purification by solubility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
DE19752500810 1974-01-11 1975-01-10 Reinigen von plasminogen Pending DE2500810A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US432789A US3865692A (en) 1974-01-11 1974-01-11 Method for making highly potent plasminogen

Publications (1)

Publication Number Publication Date
DE2500810A1 true DE2500810A1 (de) 1975-07-17

Family

ID=23717599

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752500810 Pending DE2500810A1 (de) 1974-01-11 1975-01-10 Reinigen von plasminogen

Country Status (7)

Country Link
US (1) US3865692A (ja)
JP (1) JPS5314603B2 (ja)
CA (1) CA1017696A (ja)
DE (1) DE2500810A1 (ja)
FR (1) FR2258393B1 (ja)
GB (1) GB1473245A (ja)
SE (1) SE7500172L (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082612A (en) * 1976-09-24 1978-04-04 Michael Reese Research Foundation Plasminogen activator complex
US4245051A (en) * 1978-03-30 1981-01-13 Rockefeller University Human serum plasminogen activator
JPS5716824A (en) * 1980-07-03 1982-01-28 Green Cross Corp:The Plasminogen pharmaceutical and stabilizing method thereof
JPS56106594A (en) * 1980-01-25 1981-08-24 Green Cross Corp:The Stabilizing method of plasminogen
GB2068002B (en) * 1980-01-25 1983-06-29 Green Cross Corp Plasminogen preparation and their production
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
US4774087A (en) * 1987-08-14 1988-09-27 Northwestern University Micro-size fibrinolytic plasmin
US5928772A (en) * 1996-06-13 1999-07-27 Dainippon Ink And Chemicals, Inc. Panel material and method of manufacturing the same
US6355243B1 (en) * 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US8617863B2 (en) * 2008-06-04 2013-12-31 Grifols Therapeutics Inc. Composition, method, and kit for preparing plasmin
PT2403865E (pt) * 2009-03-03 2015-11-18 Grifols Therapeutics Inc Métodos de preparação de plasminogénio

Also Published As

Publication number Publication date
JPS50100213A (ja) 1975-08-08
JPS5314603B2 (ja) 1978-05-18
FR2258393B1 (ja) 1978-06-23
FR2258393A1 (ja) 1975-08-18
GB1473245A (en) 1977-05-11
US3865692A (en) 1975-02-11
SE7500172L (ja) 1975-07-14
AU7680974A (en) 1976-06-24
CA1017696A (en) 1977-09-20

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Legal Events

Date Code Title Description
OHW Rejection