DE2355094C3 - Verfahren zur Herstellung eines Tetanus-Impfstoffs - Google Patents

Verfahren zur Herstellung eines Tetanus-Impfstoffs

Info

Publication number
DE2355094C3
DE2355094C3 DE2355094A DE2355094A DE2355094C3 DE 2355094 C3 DE2355094 C3 DE 2355094C3 DE 2355094 A DE2355094 A DE 2355094A DE 2355094 A DE2355094 A DE 2355094A DE 2355094 C3 DE2355094 C3 DE 2355094C3
Authority
DE
Germany
Prior art keywords
tetanus
toxin
vaccine
papain
molar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2355094A
Other languages
German (de)
English (en)
Other versions
DE2355094A1 (de
DE2355094B2 (de
Inventor
Torsten B. Dr. 3550 Marbach Helting
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Priority to DE2355094A priority Critical patent/DE2355094C3/de
Priority to NL7414114A priority patent/NL7414114A/xx
Priority to CA212,617A priority patent/CA1038293A/en
Priority to IL45960A priority patent/IL45960A/xx
Priority to LU71223A priority patent/LU71223A1/xx
Priority to MX550374U priority patent/MX4471E/es
Priority to US05/519,762 priority patent/US4007265A/en
Priority to IT29095/74A priority patent/IT1043904B/it
Priority to AT876674A priority patent/AT336784B/de
Priority to IE2252/74A priority patent/IE40098B1/xx
Priority to DK571574A priority patent/DK143383C/da
Priority to JP49126124A priority patent/JPS5071820A/ja
Priority to GB47526/74A priority patent/GB1492596A/en
Priority to BE150195A priority patent/BE821833A/xx
Priority to FR7436622A priority patent/FR2249679B1/fr
Priority to AU74909/74A priority patent/AU497398B2/en
Publication of DE2355094A1 publication Critical patent/DE2355094A1/de
Publication of DE2355094B2 publication Critical patent/DE2355094B2/de
Application granted granted Critical
Publication of DE2355094C3 publication Critical patent/DE2355094C3/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE2355094A 1973-11-03 1973-11-03 Verfahren zur Herstellung eines Tetanus-Impfstoffs Expired DE2355094C3 (de)

Priority Applications (16)

Application Number Priority Date Filing Date Title
DE2355094A DE2355094C3 (de) 1973-11-03 1973-11-03 Verfahren zur Herstellung eines Tetanus-Impfstoffs
NL7414114A NL7414114A (nl) 1973-11-03 1974-10-29 Atoxisch, immunogeen produkt uit tetanus-toxine.
IL45960A IL45960A (en) 1973-11-03 1974-10-30 Atoxic, immunogenic product from tetanus toxin
CA212,617A CA1038293A (en) 1973-11-03 1974-10-30 Atoxic, immunogenic product from tetanus toxin
AT876674A AT336784B (de) 1973-11-03 1974-10-31 Verfahren zur herstellung eines atoxischen, immunogenen produktes aus tetanus-toxin
MX550374U MX4471E (es) 1973-11-03 1974-10-31 Procedimiento para preparar una vacuna de tetano
US05/519,762 US4007265A (en) 1973-11-03 1974-10-31 Method for treating tetanus toxin with a proteinase to produce an atoxic immunogenic product
IT29095/74A IT1043904B (it) 1973-11-03 1974-10-31 Prodotto immunogeno atossico da tenano tossina
LU71223A LU71223A1 (enExample) 1973-11-03 1974-10-31
IE2252/74A IE40098B1 (en) 1973-11-03 1974-11-01 Tetanus toxoid and process for its manufacture
DK571574A DK143383C (da) 1973-11-03 1974-11-01 Fremgangsmaade til fremstilling af et atoksisk,immunogent produkt ud fra tetanus-toksin
JP49126124A JPS5071820A (enExample) 1973-11-03 1974-11-02
GB47526/74A GB1492596A (en) 1973-11-03 1974-11-04 Tetanus toxoid and process for its manufacture
BE150195A BE821833A (fr) 1973-11-03 1974-11-04 Produit atoxique immunogene obtenu a partir de la toxine du tetanos
FR7436622A FR2249679B1 (enExample) 1973-11-03 1974-11-04
AU74909/74A AU497398B2 (en) 1973-11-03 1974-12-31 Tetanus vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2355094A DE2355094C3 (de) 1973-11-03 1973-11-03 Verfahren zur Herstellung eines Tetanus-Impfstoffs

Publications (3)

Publication Number Publication Date
DE2355094A1 DE2355094A1 (de) 1975-05-22
DE2355094B2 DE2355094B2 (de) 1978-10-05
DE2355094C3 true DE2355094C3 (de) 1979-05-23

Family

ID=5897187

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2355094A Expired DE2355094C3 (de) 1973-11-03 1973-11-03 Verfahren zur Herstellung eines Tetanus-Impfstoffs

Country Status (15)

Country Link
US (1) US4007265A (enExample)
JP (1) JPS5071820A (enExample)
AT (1) AT336784B (enExample)
AU (1) AU497398B2 (enExample)
BE (1) BE821833A (enExample)
CA (1) CA1038293A (enExample)
DE (1) DE2355094C3 (enExample)
DK (1) DK143383C (enExample)
FR (1) FR2249679B1 (enExample)
GB (1) GB1492596A (enExample)
IE (1) IE40098B1 (enExample)
IL (1) IL45960A (enExample)
IT (1) IT1043904B (enExample)
LU (1) LU71223A1 (enExample)
NL (1) NL7414114A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200627A (en) 1976-07-31 1980-04-29 Behringwerke Aktiengesellschaft Atoxic, immunogenic product of tetanus toxin

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2510987C2 (de) 1974-10-29 1983-03-24 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tetanusimpfstoffes
DE2457047C3 (de) * 1974-12-03 1979-10-31 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Derivates der leichten Kette des Tetanustoxins, dessen Verwendung zur Tetanusprophylaxe
US4264588A (en) * 1979-05-10 1981-04-28 The Charles River Breeding Laboratories, Inc. Vaccine for Clostridium perfringens type E enterotoxemia of rabbits
US4330623A (en) * 1980-02-19 1982-05-18 Merck & Co., Inc. Process for solubilization of gonococcal antigen
FR2498192A2 (fr) * 1981-01-22 1982-07-23 Pasteur Institut Nouveau compose polypeptidique thiole provenant d'un fragment de la toxine tetanique, son procede d'obtention et ses applications
HU188847B (en) * 1983-02-22 1986-05-28 Human Oltoanyagtermeloe Es Kutato Intezet,Hu Process for producing liophylized combined vaccines
US5063162A (en) * 1987-04-24 1991-11-05 Hoffmann-La Roche Inc. Process for isolating nucleic acids utilizing protease digestion
DE3817724C2 (de) * 1988-05-25 1996-04-04 Siemens Ag Computertomograph
GB8914122D0 (en) * 1989-06-20 1989-08-09 Wellcome Found Polypeptide expression
US5601826A (en) * 1989-06-30 1997-02-11 The United States Of America As Represented By The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
US5389540A (en) * 1989-11-28 1995-02-14 Evans Medical Limited Expression of tetanus toxin fragment C in yeast
JP4229341B2 (ja) 1996-03-23 2009-02-25 財団法人阪大微生物病研究会 破傷風毒素の機能的フラグメント抗原及び破傷風ワクチン

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617344B2 (de) * 1967-05-06 1976-04-08 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines tetanus-impfstoffes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200627A (en) 1976-07-31 1980-04-29 Behringwerke Aktiengesellschaft Atoxic, immunogenic product of tetanus toxin

Also Published As

Publication number Publication date
ATA876674A (de) 1976-09-15
FR2249679B1 (enExample) 1978-07-21
LU71223A1 (enExample) 1976-08-19
GB1492596A (en) 1977-11-23
DK143383B (da) 1981-08-17
BE821833A (fr) 1975-05-05
US4007265A (en) 1977-02-01
IL45960A (en) 1979-03-12
IT1043904B (it) 1980-02-29
DE2355094A1 (de) 1975-05-22
DE2355094B2 (de) 1978-10-05
DK571574A (enExample) 1975-06-23
CA1038293A (en) 1978-09-12
DK143383C (da) 1981-12-21
IE40098B1 (en) 1979-03-14
AT336784B (de) 1977-05-25
IE40098L (en) 1975-05-03
JPS5071820A (enExample) 1975-06-14
FR2249679A1 (enExample) 1975-05-30
AU497398B2 (en) 1978-12-14
NL7414114A (nl) 1975-05-07
AU7490974A (en) 1976-05-06

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee