DE2345067A1 - Mittel zur bekaempfung der schweinedysenterie - Google Patents
Mittel zur bekaempfung der schweinedysenterieInfo
- Publication number
- DE2345067A1 DE2345067A1 DE19732345067 DE2345067A DE2345067A1 DE 2345067 A1 DE2345067 A1 DE 2345067A1 DE 19732345067 DE19732345067 DE 19732345067 DE 2345067 A DE2345067 A DE 2345067A DE 2345067 A1 DE2345067 A1 DE 2345067A1
- Authority
- DE
- Germany
- Prior art keywords
- ipronidazole
- animals
- pigs
- dysentery
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000282898 Sus scrofa Species 0.000 title claims description 26
- 208000001848 dysentery Diseases 0.000 title claims description 25
- NTAFJUSDNOSFFY-UHFFFAOYSA-N Ipronidazole Chemical compound CC(C)C1=NC=C([N+]([O-])=O)N1C NTAFJUSDNOSFFY-UHFFFAOYSA-N 0.000 claims description 36
- 229950000107 ipronidazole Drugs 0.000 claims description 34
- 241000282887 Suidae Species 0.000 claims description 24
- 150000003839 salts Chemical class 0.000 claims description 15
- 238000011282 treatment Methods 0.000 claims description 14
- 239000003651 drinking water Substances 0.000 claims description 12
- 235000020188 drinking water Nutrition 0.000 claims description 12
- 239000002253 acid Substances 0.000 claims description 9
- 238000011321 prophylaxis Methods 0.000 claims description 9
- 239000012458 free base Substances 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000003674 animal food additive Substances 0.000 claims 1
- 241001465754 Metazoa Species 0.000 description 30
- 208000004232 Enteritis Diseases 0.000 description 17
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 15
- 201000010099 disease Diseases 0.000 description 14
- 239000000203 mixture Substances 0.000 description 8
- 230000001225 therapeutic effect Effects 0.000 description 7
- 239000004480 active ingredient Substances 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 239000002585 base Substances 0.000 description 5
- 230000002008 hemorrhagic effect Effects 0.000 description 5
- 244000144980 herd Species 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 241000589893 Brachyspira hyodysenteriae Species 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 235000013312 flour Nutrition 0.000 description 4
- 238000007911 parenteral administration Methods 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 229910052918 calcium silicate Inorganic materials 0.000 description 3
- 239000000378 calcium silicate Substances 0.000 description 3
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 210000001072 colon Anatomy 0.000 description 3
- 230000034994 death Effects 0.000 description 3
- 231100000517 death Toxicity 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000000069 prophylactic effect Effects 0.000 description 3
- HOMIFIGVCCVRIG-UHFFFAOYSA-N 3-methyl-4-nitro-2-propan-2-yl-1h-imidazol-3-ium;chloride Chemical compound Cl.CC(C)C1=NC=C([N+]([O-])=O)N1C HOMIFIGVCCVRIG-UHFFFAOYSA-N 0.000 description 2
- 241000252983 Caecum Species 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- 241000607149 Salmonella sp. Species 0.000 description 2
- 210000000683 abdominal cavity Anatomy 0.000 description 2
- 210000004534 cecum Anatomy 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 229940126601 medicinal product Drugs 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 241000272517 Anseriformes Species 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 239000004243 E-number Substances 0.000 description 1
- 235000019227 E-number Nutrition 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- 208000010362 Protozoan Infections Diseases 0.000 description 1
- 235000019764 Soybean Meal Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000001578 anti-histomonal effect Effects 0.000 description 1
- 230000000842 anti-protozoal effect Effects 0.000 description 1
- 239000003904 antiprotozoal agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 239000012267 brine Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-M hydrogensulfate Chemical compound OS([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000008055 phosphate buffer solution Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000004552 water soluble powder Substances 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28939872A | 1972-09-15 | 1972-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2345067A1 true DE2345067A1 (de) | 1974-03-21 |
Family
ID=23111364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19732345067 Pending DE2345067A1 (de) | 1972-09-15 | 1973-09-06 | Mittel zur bekaempfung der schweinedysenterie |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3737546A (enExample) |
| JP (1) | JPS5239898B2 (enExample) |
| AU (1) | AU464295B2 (enExample) |
| BE (1) | BE804862A (enExample) |
| CA (1) | CA1030070A (enExample) |
| DD (1) | DD108655A5 (enExample) |
| DE (1) | DE2345067A1 (enExample) |
| GB (1) | GB1386927A (enExample) |
| IE (1) | IE38235B1 (enExample) |
| IT (1) | IT995293B (enExample) |
| PH (1) | PH10661A (enExample) |
| ZA (1) | ZA735850B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2629237A1 (de) | 1976-06-26 | 1978-01-05 | Schering Ag | Mittel zur bekaempfung von erkrankungen im veterinaerbereich |
-
1972
- 1972-09-15 US US00289398A patent/US3737546A/en not_active Expired - Lifetime
-
1973
- 1973-08-27 ZA ZA735850A patent/ZA735850B/xx unknown
- 1973-08-31 AU AU59901/73A patent/AU464295B2/en not_active Expired
- 1973-09-06 IT IT28640/73A patent/IT995293B/it active
- 1973-09-06 DE DE19732345067 patent/DE2345067A1/de active Pending
- 1973-09-10 IE IE1607/73A patent/IE38235B1/xx unknown
- 1973-09-12 CA CA180,894A patent/CA1030070A/en not_active Expired
- 1973-09-12 PH PH13013A patent/PH10661A/en unknown
- 1973-09-13 DD DD173460A patent/DD108655A5/xx unknown
- 1973-09-14 BE BE135654A patent/BE804862A/xx not_active IP Right Cessation
- 1973-09-14 GB GB4323373A patent/GB1386927A/en not_active Expired
- 1973-09-14 JP JP48103386A patent/JPS5239898B2/ja not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2629237A1 (de) | 1976-06-26 | 1978-01-05 | Schering Ag | Mittel zur bekaempfung von erkrankungen im veterinaerbereich |
Also Published As
| Publication number | Publication date |
|---|---|
| BE804862A (fr) | 1974-03-14 |
| PH10661A (en) | 1977-07-27 |
| US3737546A (en) | 1973-06-05 |
| CA1030070A (en) | 1978-04-25 |
| AU5990173A (en) | 1975-03-06 |
| IE38235B1 (en) | 1978-02-01 |
| DD108655A5 (enExample) | 1974-10-05 |
| JPS49132214A (enExample) | 1974-12-18 |
| JPS5239898B2 (enExample) | 1977-10-07 |
| AU464295B2 (en) | 1975-08-21 |
| IE38235L (en) | 1974-03-15 |
| ZA735850B (en) | 1974-07-31 |
| GB1386927A (en) | 1975-03-12 |
| IT995293B (it) | 1975-11-10 |
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