DE2314076C3 - Verfahren zur Herstellung von karzinoembyonischem Antigen - Google Patents

Verfahren zur Herstellung von karzinoembyonischem Antigen

Info

Publication number
DE2314076C3
DE2314076C3 DE2314076A DE2314076A DE2314076C3 DE 2314076 C3 DE2314076 C3 DE 2314076C3 DE 2314076 A DE2314076 A DE 2314076A DE 2314076 A DE2314076 A DE 2314076A DE 2314076 C3 DE2314076 C3 DE 2314076C3
Authority
DE
Germany
Prior art keywords
cells
cea
tumor
tumor cells
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2314076A
Other languages
German (de)
English (en)
Other versions
DE2314076A1 (de
DE2314076B2 (de
Inventor
David Milton Lexington Ky. Goldenberg (V.St.A.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Goldenberg David Milton Dr Short Hills Nj
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2314076A1 publication Critical patent/DE2314076A1/de
Publication of DE2314076B2 publication Critical patent/DE2314076B2/de
Application granted granted Critical
Publication of DE2314076C3 publication Critical patent/DE2314076C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE2314076A 1972-11-09 1973-03-21 Verfahren zur Herstellung von karzinoembyonischem Antigen Expired DE2314076C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US305197A US3865689A (en) 1972-11-09 1972-11-09 Method of producing carcinoembryonic antigens

Publications (3)

Publication Number Publication Date
DE2314076A1 DE2314076A1 (de) 1974-05-22
DE2314076B2 DE2314076B2 (de) 1980-02-28
DE2314076C3 true DE2314076C3 (de) 1980-10-16

Family

ID=23179749

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2314076A Expired DE2314076C3 (de) 1972-11-09 1973-03-21 Verfahren zur Herstellung von karzinoembyonischem Antigen

Country Status (4)

Country Link
US (1) US3865689A (index.php)
JP (1) JPS5641230B2 (index.php)
CA (1) CA1006438A (index.php)
DE (1) DE2314076C3 (index.php)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411990A (en) * 1979-06-13 1983-10-25 University Patents, Inc. Primary bioassay of human tumor stem cells
JPS58138383A (ja) * 1982-02-13 1983-08-17 Nippon Shinyaku Co Ltd 生理活性物質の製法
US4863853A (en) * 1982-04-21 1989-09-05 Bartos Patent Development And Holding Company Limited Method of determining the diagnostic value of monitoring serum-CEA-levels in a carcinoma patient undergoing therapy
JPS5871885A (ja) * 1982-08-11 1983-04-28 Terumo Corp 樹立されたヒト成長ホルモン産生細胞株
JPS5933223A (ja) * 1982-08-20 1984-02-23 Koken Kk 人の悪性腫瘍細胞増殖抑制剤
US4818709A (en) * 1983-01-21 1989-04-04 Primus Frederick J CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
US7297331B2 (en) * 1996-04-03 2007-11-20 The Rogosin Institute Beads containing restricted cancer cells producing material suppressing cancer cell proliferation
US6224912B1 (en) * 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US7318921B2 (en) * 1996-05-15 2008-01-15 Altarex Medical Corp. Therapeutic compositions that alter the immune response
US20080220012A1 (en) * 1996-05-15 2008-09-11 Ragupathy Madiyalakan Therapeutic Compositions that alter the immune response
WO1997042973A1 (en) * 1996-05-15 1997-11-20 Altarex, Corp. Method and composition for reconforming multi-epitopic antigens to initiate an immune response
US8038994B2 (en) 1996-05-15 2011-10-18 Quest Pharmatech Inc. Combination therapy for treating disease
IL139700A (en) * 1998-06-15 2005-09-25 Altarex Medical Corp Immunotherapeutic composition for the treatment of prostate cancer
AU2001261383B2 (en) * 2000-05-08 2004-10-21 Celldex Therapeutics, Inc. Human monoclonal antibodies to dendritic cells
US7129334B2 (en) * 2001-01-30 2006-10-31 Lipps Binie V Synthetic peptide and uses for same
US20050260208A1 (en) * 2002-04-11 2005-11-24 Altarex Medical Corp. Binding agents and their use in targeting tumor cells
JP4603894B2 (ja) * 2002-12-03 2010-12-22 ユセベ ファルマ ソシエテ アノニム 抗体産生細胞を同定するためのアッセイ
GB0412973D0 (en) * 2004-06-10 2004-07-14 Celltech R&D Ltd Identification of antibody producing cells

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2024458A1 (en) * 1970-05-20 1971-12-02 Hartmann geb. Ungewitter, Philippine, Dr., 8000 München Tumour antigen - modified and potentiated by irradiation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Science, 1972, 175, 1117-1118. *

Also Published As

Publication number Publication date
DE2314076A1 (de) 1974-05-22
JPS5641230B2 (index.php) 1981-09-26
US3865689A (en) 1975-02-11
CA1006438A (en) 1977-03-08
DE2314076B2 (de) 1980-02-28
JPS49100285A (index.php) 1974-09-21

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Legal Events

Date Code Title Description
OD Request for examination
C3 Grant after two publication steps (3rd publication)
8327 Change in the person/name/address of the patent owner

Owner name: GOLDENBERG, DAVID MILTON, DR., SHORT HILLS, N.J.,

8328 Change in the person/name/address of the agent

Free format text: LEDERER, F., DIPL.-CHEM. DR. MEYER-ROXLAU, R., DIPL.-ING., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee