DE2162745A1 - Verfahren zur Bestimmung des Ausreichens der Galle im Organismus - Google Patents

Verfahren zur Bestimmung des Ausreichens der Galle im Organismus

Info

Publication number
DE2162745A1
DE2162745A1 DE19712162745 DE2162745A DE2162745A1 DE 2162745 A1 DE2162745 A1 DE 2162745A1 DE 19712162745 DE19712162745 DE 19712162745 DE 2162745 A DE2162745 A DE 2162745A DE 2162745 A1 DE2162745 A1 DE 2162745A1
Authority
DE
Germany
Prior art keywords
group
peptide
fluorescein
groups
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712162745
Other languages
German (de)
English (en)
Inventor
Anthony Rocco Westerville Ohio Imondi (V.StA.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rohm and Haas Co
Original Assignee
Rohm and Haas Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohm and Haas Co filed Critical Rohm and Haas Co
Publication of DE2162745A1 publication Critical patent/DE2162745A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043—Fluorescein, used in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052—Small organic molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/062—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha- or omega-carboxy functions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE19712162745 1970-12-18 1971-12-17 Verfahren zur Bestimmung des Ausreichens der Galle im Organismus Pending DE2162745A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00099714A US3806592A (en) 1970-12-18 1970-12-18 Method for evaluating bile sufficiency

Publications (1)

Publication Number Publication Date
DE2162745A1 true DE2162745A1 (de) 1972-06-22

Family

ID=22276276

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712162745 Pending DE2162745A1 (de) 1970-12-18 1971-12-17 Verfahren zur Bestimmung des Ausreichens der Galle im Organismus

Country Status (7)

Country Link
US (1) US3806592A (https=)
BE (1) BE776873A (https=)
CA (1) CA984750A (https=)
DE (1) DE2162745A1 (https=)
FR (1) FR2118178B1 (https=)
GB (1) GB1382240A (https=)
NL (1) NL7117216A (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795418A (fr) * 1972-05-24 1973-08-14 Rohm & Haas Procede d'acylation directe des acides aminobenzoiques
ATE173637T1 (de) * 1990-07-19 1998-12-15 Unicliffe Ltd Diagnostisches mittel zur bestimmung von pankreasinsuffiziens
GB2251381B (en) * 1990-07-19 1995-01-25 Charwell Pharma Emulsified fluorescein diester diagnostic compositions
US5506147A (en) * 1993-04-15 1996-04-09 Kolhouse; J. Fred Non-invasive evaluation of maldigestion and malaborption
US6159445A (en) * 1994-07-20 2000-12-12 Nycomed Imaging As Light imaging contrast agents
GB9502065D0 (en) * 1995-02-02 1995-03-22 Nycomed Imaging As Contrast media
US6540981B2 (en) 1997-12-04 2003-04-01 Amersham Health As Light imaging contrast agents
US6663846B1 (en) * 1998-12-21 2003-12-16 Mccombs Candace Devices and methods for monitoring drug therapy compliance
WO2018026538A1 (en) * 2016-08-02 2018-02-08 ISI Life Sciences Inc. Novel scaffolds for intracellular compound delivery for the detection of cancer cells
US10239891B2 (en) 2017-05-15 2019-03-26 Indicator Systems International, Inc. Compositions to detect remnant cancer cells
WO2018026965A1 (en) 2016-08-02 2018-02-08 Isi Life Sciences, Inc. Compositions and methods for detecting cancer cells in a tissue sample
US10753942B2 (en) 2017-05-15 2020-08-25 Indicator Systems International, Inc. Methods to detect remnant cancer cells

Also Published As

Publication number Publication date
FR2118178B1 (https=) 1975-08-01
CA984750A (en) 1976-03-02
US3806592A (en) 1974-04-23
GB1382240A (en) 1975-01-29
FR2118178A1 (https=) 1972-07-28
NL7117216A (https=) 1972-06-20
BE776873A (fr) 1972-06-19

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Legal Events

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OD Request for examination
OHW Rejection