DE2145892C3 - Verfahren zur Gewinnung von 5-Fluoruracil - Google Patents

Verfahren zur Gewinnung von 5-Fluoruracil

Info

Publication number
DE2145892C3
DE2145892C3 DE19712145892 DE2145892A DE2145892C3 DE 2145892 C3 DE2145892 C3 DE 2145892C3 DE 19712145892 DE19712145892 DE 19712145892 DE 2145892 A DE2145892 A DE 2145892A DE 2145892 C3 DE2145892 C3 DE 2145892C3
Authority
DE
Germany
Prior art keywords
uracil
reaction mixture
until
fluorine
fluorouracil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19712145892
Other languages
German (de)
English (en)
Other versions
DE2145892A1 (de
DE2145892B2 (de
Inventor
Lew S. German
Solomon A. Giller
Iwan L. Knunjanz
Natalja B. Kusmina
Arwid A. Lasdinsch
Dagnija J. Sniker
Artur K. Wejnberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST ELEMENTOORGANICHESKIKH SO
INST ORGANICHESKOGO SINTEZA AK
Original Assignee
INST ELEMENTOORGANICHESKIKH SO
INST ORGANICHESKOGO SINTEZA AK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SU1472781A external-priority patent/SU322053A1/ru
Application filed by INST ELEMENTOORGANICHESKIKH SO, INST ORGANICHESKOGO SINTEZA AK filed Critical INST ELEMENTOORGANICHESKIKH SO
Publication of DE2145892A1 publication Critical patent/DE2145892A1/de
Publication of DE2145892B2 publication Critical patent/DE2145892B2/de
Application granted granted Critical
Publication of DE2145892C3 publication Critical patent/DE2145892C3/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19712145892 1970-09-24 1971-09-14 Verfahren zur Gewinnung von 5-Fluoruracil Expired DE2145892C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU1472781A SU322053A1 (ru) 1970-09-24 Способ получения 5-фторурацила

Publications (3)

Publication Number Publication Date
DE2145892A1 DE2145892A1 (de) 1972-03-30
DE2145892B2 DE2145892B2 (de) 1975-02-13
DE2145892C3 true DE2145892C3 (de) 1975-10-09

Family

ID=20456938

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712145892 Expired DE2145892C3 (de) 1970-09-24 1971-09-14 Verfahren zur Gewinnung von 5-Fluoruracil

Country Status (7)

Country Link
BE (1) BE772867A (enrdf_load_stackoverflow)
CH (1) CH572043A5 (enrdf_load_stackoverflow)
DE (1) DE2145892C3 (enrdf_load_stackoverflow)
FR (1) FR2107933B1 (enrdf_load_stackoverflow)
GB (1) GB1323785A (enrdf_load_stackoverflow)
NL (1) NL7112865A (enrdf_load_stackoverflow)
SE (1) SE386442B (enrdf_load_stackoverflow)

Also Published As

Publication number Publication date
FR2107933B1 (enrdf_load_stackoverflow) 1975-02-07
DE2145892A1 (de) 1972-03-30
SE386442B (sv) 1976-08-09
FR2107933A1 (enrdf_load_stackoverflow) 1972-05-12
DE2145892B2 (de) 1975-02-13
BE772867A (fr) 1972-03-21
NL7112865A (enrdf_load_stackoverflow) 1972-03-28
CH572043A5 (enrdf_load_stackoverflow) 1976-01-30
GB1323785A (en) 1973-07-18

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
8339 Ceased/non-payment of the annual fee