DE2128744C3 - Verfahren zur Massenkultivation von Zellen und Geweben - Google Patents

Verfahren zur Massenkultivation von Zellen und Geweben

Info

Publication number
DE2128744C3
DE2128744C3 DE2128744A DE2128744A DE2128744C3 DE 2128744 C3 DE2128744 C3 DE 2128744C3 DE 2128744 A DE2128744 A DE 2128744A DE 2128744 A DE2128744 A DE 2128744A DE 2128744 C3 DE2128744 C3 DE 2128744C3
Authority
DE
Germany
Prior art keywords
cells
carbon dioxide
value
cultivation
pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2128744A
Other languages
German (de)
English (en)
Other versions
DE2128744A1 (de
DE2128744B2 (de
Inventor
Donald S. 7800 Freiburg Hoelzl-Wallach
Manuel Dipl.- Chem. 7801 Bollschweil Modolell
Paul Gerhard Dr. 7830 Emmendingen Munder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority to DE2128744A priority Critical patent/DE2128744C3/de
Priority to BE784219A priority patent/BE784219A/xx
Priority to CH828172A priority patent/CH573472A5/xx
Priority to SE7207444A priority patent/SE407422B/xx
Priority to US260629A priority patent/US3873423A/en
Priority to FR7220667A priority patent/FR2140576B1/fr
Priority to IT50755/72A priority patent/IT958261B/it
Priority to AT494972A priority patent/AT316755B/de
Priority to NL7207796A priority patent/NL7207796A/xx
Priority to DK286772A priority patent/DK145380C/da
Priority to GB2716972A priority patent/GB1389411A/en
Priority to GB3325374A priority patent/GB1389412A/en
Publication of DE2128744A1 publication Critical patent/DE2128744A1/de
Priority to US05/560,632 priority patent/US3941662A/en
Publication of DE2128744B2 publication Critical patent/DE2128744B2/de
Application granted granted Critical
Publication of DE2128744C3 publication Critical patent/DE2128744C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/24—Gas permeable parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE2128744A 1971-06-09 1971-06-09 Verfahren zur Massenkultivation von Zellen und Geweben Expired DE2128744C3 (de)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DE2128744A DE2128744C3 (de) 1971-06-09 1971-06-09 Verfahren zur Massenkultivation von Zellen und Geweben
BE784219A BE784219A (fr) 1971-06-09 1972-05-31 Procede de culture en serie de cellules et tissus et recipient pour la mise en oeuvre du procede
CH828172A CH573472A5 (OSRAM) 1971-06-09 1972-06-05
US260629A US3873423A (en) 1971-06-09 1972-06-07 Method for culturing cells
SE7207444A SE407422B (sv) 1971-06-09 1972-06-07 Forfarande for odling av celler och vevnader samt anordning for genomforande av forfarandet
IT50755/72A IT958261B (it) 1971-06-09 1972-06-08 Recipiente per coltivare in massa cellule e tessuti e relativo procedimento per produrre cellule e tessuti
FR7220667A FR2140576B1 (OSRAM) 1971-06-09 1972-06-08
AT494972A AT316755B (de) 1971-06-09 1972-06-08 Verfahren zur Massenkultivation von Zellen und Geweben und Behälter zur Durchführung des Verfahrens
NL7207796A NL7207796A (OSRAM) 1971-06-09 1972-06-08
DK286772A DK145380C (da) 1971-06-09 1972-06-08 Fremgangsmaade til massedyrkning af celler og vaev og beholder til udfoerelse af fremgangsmaaden
GB2716972A GB1389411A (en) 1971-06-09 1972-06-09 Cultivation of cells and tissues
GB3325374A GB1389412A (en) 1971-06-09 1972-06-09 Cultivation chambers
US05/560,632 US3941662A (en) 1971-06-09 1975-03-21 Apparatus for culturing cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2128744A DE2128744C3 (de) 1971-06-09 1971-06-09 Verfahren zur Massenkultivation von Zellen und Geweben

Publications (3)

Publication Number Publication Date
DE2128744A1 DE2128744A1 (de) 1972-12-28
DE2128744B2 DE2128744B2 (de) 1978-08-03
DE2128744C3 true DE2128744C3 (de) 1979-03-29

Family

ID=5810351

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2128744A Expired DE2128744C3 (de) 1971-06-09 1971-06-09 Verfahren zur Massenkultivation von Zellen und Geweben

Country Status (11)

Country Link
US (1) US3873423A (OSRAM)
AT (1) AT316755B (OSRAM)
BE (1) BE784219A (OSRAM)
CH (1) CH573472A5 (OSRAM)
DE (1) DE2128744C3 (OSRAM)
DK (1) DK145380C (OSRAM)
FR (1) FR2140576B1 (OSRAM)
GB (2) GB1389412A (OSRAM)
IT (1) IT958261B (OSRAM)
NL (1) NL7207796A (OSRAM)
SE (1) SE407422B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336329A (en) 1979-06-18 1982-06-22 W. C. Heraeus Gmbh Method and apparatus for treatment of biological substances, particularly for cultivation of biological cells and tissues, or of microorganisms

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959074A (en) * 1972-06-14 1976-05-25 Merck & Co., Inc. Vaccine production
US3887436A (en) * 1973-05-31 1975-06-03 Instrumentation Labor Inc Cell culturing system
US4033825A (en) * 1973-05-31 1977-07-05 Instrumentation Laboratory, Inc. Cell culture system
CH593339A5 (OSRAM) * 1973-07-02 1977-11-30 Monsanto Co
GB1490586A (en) * 1974-08-22 1977-11-02 Instrumentation Labor Inc Apparatus for culturing cells
US4144126A (en) * 1975-05-21 1979-03-13 Beecham Group Limited Cell culture method
US4024020A (en) * 1975-12-15 1977-05-17 Monsanto Company Method of cell culture on polyacrylonitrile surface
DE2624047C3 (de) * 1976-05-28 1980-07-03 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Massenzüchtung von Zellen und Kammer-System zu ihrer Durchführung
DE2726313C3 (de) * 1977-06-10 1980-02-07 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin
US4296204A (en) * 1978-01-25 1981-10-20 Merck & Co., Inc. Use of motionless mixer as cell culture propagator
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
US4411990A (en) * 1979-06-13 1983-10-25 University Patents, Inc. Primary bioassay of human tumor stem cells
US4298002A (en) * 1979-09-10 1981-11-03 National Patent Development Corporation Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation
US4415670A (en) * 1980-07-07 1983-11-15 Merck & Co., Inc. Motionless mixer as cell culture propagator
KR870001649B1 (ko) * 1980-11-26 1987-09-18 가부시기가이샤 히다찌 세이사꾸쇼 미생물 배양제어방법 및 장치
US4416993A (en) 1981-06-11 1983-11-22 Mcleod & Miller (Engineers) Limited Apparatus with semi-permeable membrane, and method for cultivating micro-organisms
CS231615B1 (en) * 1981-12-29 1984-12-14 Vladislav Vlcek Method of cultivation of cells of higher organism and device to perform the method
JPS60141286A (ja) * 1983-12-28 1985-07-26 Ajinomoto Co Inc 動物細胞の培養方法および装置
US4680267A (en) * 1985-03-01 1987-07-14 New Brunswick Scientific Company, Inc. Fermentor control system
DE3515753C2 (de) * 1985-05-02 1987-03-05 Hans 4156 Willich Preisendanz Verfahren zur Bestimmung der Wirkung von Chemotherapeutika auf das Wachstum von Mikroorganismen und/oder Zellen und Verwendung einer Vorrichtung mit mehreren Kammern zu seiner Durchführung
DE3786213T2 (de) * 1986-09-19 1993-09-30 Shimadzu Corp Druckbrutschrank.
FR2780525B1 (fr) * 1998-06-24 2001-04-13 Jouan Enceinte de travail thermostatee
GB2339763A (en) * 1998-07-24 2000-02-09 Applied Photosynthetics Limite Partitioned bag for use as photobioreactor
EP2284253B2 (de) * 1999-09-08 2020-05-27 Levitronix Technologies, LLC Bioreaktor
EP3943591A1 (en) 2003-10-08 2022-01-26 Wilson Wolf Manufacturing Corporation Cell culture methods and devices utilizing gas permeable materials
US20050221486A1 (en) * 2004-03-25 2005-10-06 Human Genome Sciences, Inc. Cell culture apparatus and methods
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
CA2671812C (en) * 2006-12-07 2015-06-16 Wilson Wolf Manufacturing Corporation Highly efficient gas permeable devices and methods for culturing cells
US8518692B2 (en) * 2008-07-08 2013-08-27 Wilson Wolf Manufacturing Corporation Gas permeable cell culture device and method of use
EP3135752A4 (en) * 2014-04-22 2018-03-14 Nippon Shokubai Co., Ltd. Cell culture substrate containing fluorine-containing polymer on surface
US9926524B2 (en) 2014-12-22 2018-03-27 Saint-Gobain Performance Plastics Corporation Gas permeable material
GB201521136D0 (en) 2015-12-01 2016-01-13 Arborea Ltd Device
GB201708940D0 (en) * 2017-06-05 2017-07-19 Arborea Ltd Photo-bioreactor device and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3545221A (en) * 1967-05-22 1970-12-08 Swenko Research & Dev Inc Apparatus for maintaining organs in vitro in a completely viable state
GB1312447A (en) * 1969-05-14 1973-04-04 Nat Res Dev Method of continuous addition of a component to a chemical or biological system and apparatus therefor
US3660242A (en) * 1970-03-05 1972-05-02 Schmid Inc Julius Incubator

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336329A (en) 1979-06-18 1982-06-22 W. C. Heraeus Gmbh Method and apparatus for treatment of biological substances, particularly for cultivation of biological cells and tissues, or of microorganisms

Also Published As

Publication number Publication date
DK145380B (da) 1982-11-08
US3873423A (en) 1975-03-25
DK145380C (da) 1983-04-05
CH573472A5 (OSRAM) 1976-03-15
DE2128744A1 (de) 1972-12-28
SE407422B (sv) 1979-03-26
AT316755B (de) 1974-07-25
GB1389412A (en) 1975-04-03
FR2140576A1 (OSRAM) 1973-01-19
DE2128744B2 (de) 1978-08-03
BE784219A (fr) 1972-09-18
FR2140576B1 (OSRAM) 1977-12-23
GB1389411A (en) 1975-04-03
NL7207796A (OSRAM) 1972-12-12
IT958261B (it) 1973-10-20

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee