DE19843222A1 - Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen - Google Patents
Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von InfektionenInfo
- Publication number
- DE19843222A1 DE19843222A1 DE19843222A DE19843222A DE19843222A1 DE 19843222 A1 DE19843222 A1 DE 19843222A1 DE 19843222 A DE19843222 A DE 19843222A DE 19843222 A DE19843222 A DE 19843222A DE 19843222 A1 DE19843222 A1 DE 19843222A1
- Authority
- DE
- Germany
- Prior art keywords
- substituted
- viruses
- unsubstituted
- genus
- bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 208000015181 infectious disease Diseases 0.000 title claims abstract description 14
- 150000002903 organophosphorus compounds Chemical class 0.000 title claims abstract description 14
- 238000011321 prophylaxis Methods 0.000 title claims abstract description 8
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- 230000000855 fungicidal effect Effects 0.000 claims abstract description 7
- 230000002363 herbicidal effect Effects 0.000 claims abstract description 6
- 239000003899 bactericide agent Substances 0.000 claims abstract description 5
- 239000000417 fungicide Substances 0.000 claims abstract description 5
- 239000004009 herbicide Substances 0.000 claims abstract description 5
- -1 heterocyclic radical Chemical class 0.000 claims description 135
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- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims description 22
- 241000282412 Homo Species 0.000 claims description 20
- 239000004480 active ingredient Substances 0.000 claims description 19
- 125000000217 alkyl group Chemical group 0.000 claims description 19
- 239000001257 hydrogen Substances 0.000 claims description 19
- 229910052739 hydrogen Inorganic materials 0.000 claims description 19
- 125000003118 aryl group Chemical group 0.000 claims description 18
- 229910052736 halogen Inorganic materials 0.000 claims description 16
- 125000002252 acyl group Chemical group 0.000 claims description 15
- 125000000304 alkynyl group Chemical group 0.000 claims description 15
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 15
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 14
- 150000003839 salts Chemical class 0.000 claims description 14
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- 238000011282 treatment Methods 0.000 claims description 13
- 125000004432 carbon atom Chemical group C* 0.000 claims description 12
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- 150000003863 ammonium salts Chemical class 0.000 claims description 7
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
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- SGKRLCUYIXIAHR-AKNGSSGZSA-N (4s,4ar,5s,5ar,6r,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1=CC=C2[C@H](C)[C@@H]([C@H](O)[C@@H]3[C@](C(O)=C(C(N)=O)C(=O)[C@H]3N(C)C)(O)C3=O)C3=C(O)C2=C1O SGKRLCUYIXIAHR-AKNGSSGZSA-N 0.000 claims description 6
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- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 claims description 6
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- AEUTYOVWOVBAKS-UWVGGRQHSA-N ethambutol Chemical compound CC[C@@H](CO)NCCN[C@@H](CC)CO AEUTYOVWOVBAKS-UWVGGRQHSA-N 0.000 claims description 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 6
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 claims description 6
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- MQJKPEGWNLWLTK-UHFFFAOYSA-N Dapsone Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=C1 MQJKPEGWNLWLTK-UHFFFAOYSA-N 0.000 claims description 5
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- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 claims description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 4
- GNWUOVJNSFPWDD-XMZRARIVSA-M Cefoxitin sodium Chemical group [Na+].N([C@]1(OC)C(N2C(=C(COC(N)=O)CS[C@@H]21)C([O-])=O)=O)C(=O)CC1=CC=CS1 GNWUOVJNSFPWDD-XMZRARIVSA-M 0.000 claims description 4
- 235000001258 Cinchona calisaya Nutrition 0.000 claims description 4
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- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims description 4
- 241000700721 Hepatitis B virus Species 0.000 claims description 4
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- PJSFRIWCGOHTNF-UHFFFAOYSA-N Sulphormetoxin Chemical compound COC1=NC=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=C1OC PJSFRIWCGOHTNF-UHFFFAOYSA-N 0.000 claims description 4
- 208000000260 Warts Diseases 0.000 claims description 4
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 4
- DZBUGLKDJFMEHC-UHFFFAOYSA-N acridine Chemical compound C1=CC=CC2=CC3=CC=CC=C3N=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-N 0.000 claims description 4
- 230000000840 anti-viral effect Effects 0.000 claims description 4
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- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 claims description 4
- 229930101531 artemisinin Natural products 0.000 claims description 4
- JFIOVJDNOJYLKP-UHFFFAOYSA-N bithionol Chemical compound OC1=C(Cl)C=C(Cl)C=C1SC1=CC(Cl)=CC(Cl)=C1O JFIOVJDNOJYLKP-UHFFFAOYSA-N 0.000 claims description 4
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- WHTVZRBIWZFKQO-UHFFFAOYSA-N chloroquine Natural products ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-UHFFFAOYSA-N 0.000 claims description 4
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 claims description 4
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- KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 claims description 4
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- RJMUSRYZPJIFPJ-UHFFFAOYSA-N niclosamide Chemical compound OC1=CC=C(Cl)C=C1C(=O)NC1=CC=C([N+]([O-])=O)C=C1Cl RJMUSRYZPJIFPJ-UHFFFAOYSA-N 0.000 claims description 4
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- 229910052757 nitrogen Inorganic materials 0.000 claims description 4
- OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 claims description 4
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- WCMIIGXFCMNQDS-IDYPWDAWSA-M piperacillin sodium Chemical compound [Na+].O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C([O-])=O)C(C)(C)S[C@@H]21 WCMIIGXFCMNQDS-IDYPWDAWSA-M 0.000 claims description 4
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- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dentistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Agronomy & Crop Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (38)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843222A DE19843222A1 (de) | 1998-09-22 | 1998-09-22 | Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen |
| KR1020007011421A KR20010034783A (ko) | 1998-04-14 | 1999-04-13 | 감염의 치료학적 및 예방학적 치료용 유기 인 화합물의 용도 |
| DE59907376T DE59907376D1 (de) | 1998-04-14 | 1999-04-13 | Verwendung von phosphororganischen verbindungen zur therapeutischen und prophylaktischen behandlung von infektionen |
| SK1522-2000A SK15222000A3 (sk) | 1998-04-14 | 1999-04-13 | Použitie organofosforových zlúčenín na liečbu a profylaxiu infekcií |
| IL13888199A IL138881A0 (en) | 1998-04-14 | 1999-04-13 | Use of organophosphorus compounds for therapeutic and prophylactic treatment of infection |
| PCT/EP1999/002462 WO1999052515A2 (fr) | 1998-04-14 | 1999-04-13 | Utilisation de liaisons organophosphorees dans le traitement et la prevention d'infections |
| JP2000543125A JP3657516B2 (ja) | 1998-04-14 | 1999-04-13 | 感染症の治療および予防処置のための有機リン化合物の使用 |
| EP99919226A EP1071409B1 (fr) | 1998-04-14 | 1999-04-13 | Utilisation de liaisons organophosphorees dans le traitement et la prevention d'infections |
| CA2328159A CA2328159C (fr) | 1998-04-14 | 1999-04-13 | Utilisation de derives de l'acide aminoalkylphosphonique pour le traitement therapeutique et de prevention d'infections |
| OA1200000279A OA11538A (en) | 1998-04-14 | 1999-04-13 | Use of organophosphoric compounds for the therapeutic and preventative treatment of infections |
| BR9909668-4A BR9909668A (pt) | 1998-04-14 | 1999-04-13 | Uso de compostos de organofósforo para o tratamento terapêutico e profilático de infecções |
| HU0101716A HUP0101716A3 (en) | 1998-04-14 | 1999-04-13 | Use of organo phosphonic and phosphinic acid derivatives for producing medicaments useful for therapeutic and preventative treatment of infections |
| EA200001065A EA200001065A1 (ru) | 1998-04-14 | 1999-04-13 | Применение фосфорорганических соединений для терапевтического и профилактического лечения инфекций |
| MXPA00010068A MXPA00010068A (es) | 1998-04-14 | 1999-04-13 | Uso de compuestos organofosforicos para el tratamiento terapeutico y preventivo de infecciones. |
| TR2000/02965T TR200002965T2 (tr) | 1998-04-14 | 1999-04-13 | Enfeksiyonların terapötik ve profilaktik tedavisi için organofosforlu terkiplerin kullanımı |
| US09/673,561 US6680308B1 (en) | 1998-04-14 | 1999-04-13 | Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections |
| AT99919226T ATE251903T1 (de) | 1998-04-14 | 1999-04-13 | Verwendung von phosphororganischen verbindungen zur therapeutischen und prophylaktischen behandlung von infektionen |
| APAP/P/2000/001942A AP2000001942A0 (en) | 1998-04-14 | 1999-04-13 | Use of organophosphoric compounds for the therapeutic and preventative treatment of infections. |
| AU41208/99A AU747407B2 (en) | 1998-04-14 | 1999-04-13 | Use of organophosphoric compounds for the therapeutic and preventative treatment of infections |
| CN99805115A CN1297352A (zh) | 1998-04-14 | 1999-04-13 | 有机磷化合物在治疗和预防性治疗感染中的应用 |
| PL99344535A PL344535A1 (en) | 1998-04-14 | 1999-04-13 | Use of organophosphoric compounds for the therapeutic and preventative treatment of infections |
| OA1200100073A OA11655A (en) | 1998-09-22 | 1999-09-22 | Use of organophosphorous compounds for producing medicaments for the therapeutic and prophylactic treatment of infections or as a fungicide, bactericide or herbicide for plants. |
| AU59811/99A AU5981199A (en) | 1998-09-22 | 1999-09-22 | Use of organophosphorous compounds for producing medicaments for the therapeuticand prophylactic treatment of infections or as a fungicide, bactericide or herb icide for plants |
| BR9913990-1A BR9913990A (pt) | 1998-09-22 | 1999-09-22 | Uso de compostos organofosforados para a produção de preparações farmacêuticas para o tratamento terapêutico e profilático de infecções ou como um fungicida, bactericida ou herbicida em plantas |
| ZA200101912A ZA200101912B (en) | 1998-09-22 | 1999-09-22 | Use of organophosphorous compounds for producing medicaments for the therapeutic and prophylactic treatment of infections or as a fungicide, bactericide or herbicide for plants. |
| PCT/EP1999/007054 WO2000016757A2 (fr) | 1998-09-22 | 1999-09-22 | Utilisation de composes organophosphores pour la production de medicaments pour le traitement therapeutique et prophylactique d'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux |
| SK393-2001A SK3932001A3 (en) | 1998-09-22 | 1999-09-22 | USE OF ORGANOPHOSPHOROUS COMPOUNDS FOR PRODUCING MEDICAMENTS FORì (54) THE THERAPEUTIC AND PROPHYLACTIC TREATMENT OF INFECTIONS OR ASì (54) A FUNGICIDE, BACTERICIDE OR HERBICIDE FOR PLANTS |
| IL14188799A IL141887A0 (en) | 1998-09-22 | 1999-09-22 | Use of organophosphorous compounds for producing medicaments for the therapeutic and prophylactic treatment of infections or as a fungicide, bactericide or herbicide for plants |
| KR1020017003601A KR20010075248A (ko) | 1998-09-22 | 1999-09-22 | 유기인계 화합물을 포함하는, 감염의 치료학적 및 예방학적 치료용 약제학적 조성물 또는 식물의 살진균제, 살균제 또는 제초제로서의 약제학적 조성물 |
| APAP/P/2001/002106A AP2001002106A0 (en) | 1998-09-22 | 1999-09-22 | Use of organophosphorus compounds for producing medicaments for the therapeutic and prophylactic treatment of infections or as a fungicide, bactericide or herbicide. |
| PL99353313A PL353313A1 (en) | 1998-09-22 | 1999-09-22 | Use of organophosphorous compounds for producing medicaments for the therapeutic and prophylactic treatment of infections or as a fungicide, bactericide or herbicide for plants |
| EP99969332A EP1115388A1 (fr) | 1998-09-22 | 1999-09-22 | Utilisation de composes organophosphores pour la production de medicaments pour le traitement therapeutique et prophylactique d'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux |
| JP2000573718A JP2003520760A (ja) | 1998-09-22 | 1999-09-22 | 感染症の治療および予防処置用医薬製剤の製造のための、または植物における殺真菌剤、殺菌剤もしくは除草剤としての使用 |
| CN99811158A CN1319006A (zh) | 1998-09-22 | 1999-09-22 | 有机磷化合物在制备用于治疗或预防性治疗感染的药物或者在植物中作为杀真菌剂、杀菌剂或除草剂的用途 |
| CA002344867A CA2344867A1 (fr) | 1998-09-22 | 1999-09-22 | Utilisation des derives de l'acide aminoalkylphosphonique pour la production de medicaments pour le traitement therapeutique et prophylactique dd'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux |
| NO20011430A NO20011430L (no) | 1998-09-22 | 2001-03-21 | Anvendelse av organofosforforbindelser for fremstilling av medikamenter for terapeutisk og profylaktisk behandling avinfeksjoner, eller som et fungicid, baktericid eller herbicid forplanter |
| US10/676,131 US20040082549A1 (en) | 1998-04-14 | 2003-10-02 | Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections |
| US13/159,027 US20110306578A1 (en) | 1998-04-14 | 2011-06-13 | Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843222A DE19843222A1 (de) | 1998-09-22 | 1998-09-22 | Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19843222A1 true DE19843222A1 (de) | 2000-03-30 |
Family
ID=7881691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19843222A Withdrawn DE19843222A1 (de) | 1998-04-14 | 1998-09-22 | Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1115388A1 (fr) |
| JP (1) | JP2003520760A (fr) |
| KR (1) | KR20010075248A (fr) |
| CN (1) | CN1319006A (fr) |
| AP (1) | AP2001002106A0 (fr) |
| AU (1) | AU5981199A (fr) |
| BR (1) | BR9913990A (fr) |
| CA (1) | CA2344867A1 (fr) |
| DE (1) | DE19843222A1 (fr) |
| IL (1) | IL141887A0 (fr) |
| NO (1) | NO20011430L (fr) |
| OA (1) | OA11655A (fr) |
| PL (1) | PL353313A1 (fr) |
| SK (1) | SK3932001A3 (fr) |
| WO (1) | WO2000016757A2 (fr) |
| ZA (1) | ZA200101912B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002004002A2 (fr) * | 2000-07-11 | 2002-01-17 | Bayer Aktiengesellschaft | Utilisation de souches du virus parapox ovis pour la fabrication de medicaments antiviraux et anticancereux |
| WO2002078714A1 (fr) * | 2001-03-30 | 2002-10-10 | Jomaa Pharmaka Gmbh | Formulations gastro-resistantes de composes anti-infectieux, bloquant la voie metabolique de la 2-c-methylerythrose-4, ainsi que leurs sels et esters |
| PL3010511T3 (pl) | 2014-09-12 | 2018-07-31 | Antibiotx A/S | Przeciwbakteryjne zastosowanie halogenowanych salicylanilidów |
| GB201509326D0 (en) | 2015-05-29 | 2015-07-15 | Antibio Tx Aps | Novel use |
| CN105055431B (zh) * | 2015-08-11 | 2018-03-13 | 西南医科大学附属医院 | 一种具有抗结核菌的药物及其应用 |
| CN108853106B (zh) * | 2017-05-09 | 2021-02-02 | 中国食品药品检定研究院 | 亚胺吩嗪类化合物作为狂犬病病毒抑制剂的用途 |
| US11419834B2 (en) | 2019-02-25 | 2022-08-23 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide |
| CA3172672A1 (fr) * | 2020-03-26 | 2021-09-30 | Jei Man Ryu | Composition pharmaceutique pour prevenir ou traiter une maladie infectieuse epidemique a virus a arn |
| CN112043707B (zh) * | 2020-09-09 | 2021-07-30 | 武汉珈创生物技术股份有限公司 | 氯法齐明和/或其可药用衍生物在制备抗沙粒病毒药物中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS542336A (en) * | 1977-06-06 | 1979-01-09 | Meiji Seika Kaisha Ltd | Preventive and remedy for viral diseases |
| AU566627B2 (en) * | 1983-08-02 | 1987-10-22 | Omura, S. | Herbicidal antibiotic |
| US4693742A (en) * | 1983-12-20 | 1987-09-15 | Rohm And Hass Company | Herbicidal hydroxyamino phosphonic acids and derivatives |
| US4846872A (en) * | 1986-08-11 | 1989-07-11 | Fujisawa Pharmaceutical Co., Ltd. | Herbicide |
| JP2606296B2 (ja) * | 1988-07-05 | 1997-04-30 | 住友化学工業株式会社 | 除草組成物 |
| WO1996016629A2 (fr) * | 1994-11-18 | 1996-06-06 | Amira Inc | Composes phosphinico-creatiniques a activite antivirale |
| CN1297352A (zh) * | 1998-04-14 | 2001-05-30 | 哈桑·朱马 | 有机磷化合物在治疗和预防性治疗感染中的应用 |
-
1998
- 1998-09-22 DE DE19843222A patent/DE19843222A1/de not_active Withdrawn
-
1999
- 1999-09-22 CA CA002344867A patent/CA2344867A1/fr not_active Abandoned
- 1999-09-22 BR BR9913990-1A patent/BR9913990A/pt not_active Application Discontinuation
- 1999-09-22 IL IL14188799A patent/IL141887A0/xx unknown
- 1999-09-22 JP JP2000573718A patent/JP2003520760A/ja active Pending
- 1999-09-22 CN CN99811158A patent/CN1319006A/zh active Pending
- 1999-09-22 AU AU59811/99A patent/AU5981199A/en not_active Abandoned
- 1999-09-22 PL PL99353313A patent/PL353313A1/xx unknown
- 1999-09-22 SK SK393-2001A patent/SK3932001A3/sk unknown
- 1999-09-22 EP EP99969332A patent/EP1115388A1/fr not_active Withdrawn
- 1999-09-22 KR KR1020017003601A patent/KR20010075248A/ko not_active Application Discontinuation
- 1999-09-22 OA OA1200100073A patent/OA11655A/en unknown
- 1999-09-22 ZA ZA200101912A patent/ZA200101912B/en unknown
- 1999-09-22 WO PCT/EP1999/007054 patent/WO2000016757A2/fr not_active Application Discontinuation
- 1999-09-22 AP APAP/P/2001/002106A patent/AP2001002106A0/en unknown
-
2001
- 2001-03-21 NO NO20011430A patent/NO20011430L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003520760A (ja) | 2003-07-08 |
| ZA200101912B (en) | 2002-03-07 |
| SK3932001A3 (en) | 2001-08-06 |
| WO2000016757A8 (fr) | 2000-06-29 |
| WO2000016757A2 (fr) | 2000-03-30 |
| CN1319006A (zh) | 2001-10-24 |
| KR20010075248A (ko) | 2001-08-09 |
| NO20011430L (no) | 2001-05-09 |
| NO20011430D0 (no) | 2001-03-21 |
| BR9913990A (pt) | 2001-10-23 |
| CA2344867A1 (fr) | 2000-03-30 |
| AU5981199A (en) | 2000-04-10 |
| OA11655A (en) | 2004-12-08 |
| IL141887A0 (en) | 2002-03-10 |
| AP2001002106A0 (en) | 2001-03-31 |
| PL353313A1 (en) | 2003-11-17 |
| EP1115388A1 (fr) | 2001-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| 8127 | New person/name/address of the applicant |
Owner name: JOMAA PHARMAKA GMBH, 35392 GIESSEN, DE |
|
| 8181 | Inventor (new situation) |
Free format text: JOMAA, HASSAN, DR., 35398 GIESSEN, DE |
|
| 8139 | Disposal/non-payment of the annual fee |