CA2344867A1 - Utilisation des derives de l'acide aminoalkylphosphonique pour la production de medicaments pour le traitement therapeutique et prophylactique dd'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux - Google Patents
Utilisation des derives de l'acide aminoalkylphosphonique pour la production de medicaments pour le traitement therapeutique et prophylactique dd'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux Download PDFInfo
- Publication number
- CA2344867A1 CA2344867A1 CA002344867A CA2344867A CA2344867A1 CA 2344867 A1 CA2344867 A1 CA 2344867A1 CA 002344867 A CA002344867 A CA 002344867A CA 2344867 A CA2344867 A CA 2344867A CA 2344867 A1 CA2344867 A1 CA 2344867A1
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- Canada
- Prior art keywords
- substituted
- viruses
- unsubstituted
- genus
- bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 208000015181 infectious disease Diseases 0.000 title claims abstract description 15
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 11
- 230000000855 fungicidal effect Effects 0.000 title claims abstract description 8
- 230000002363 herbicidal effect Effects 0.000 title claims abstract description 8
- 239000004009 herbicide Substances 0.000 title claims abstract description 8
- 238000011321 prophylaxis Methods 0.000 title claims abstract description 8
- 239000003899 bactericide agent Substances 0.000 title claims abstract description 7
- 239000000417 fungicide Substances 0.000 title claims abstract description 7
- 230000001225 therapeutic effect Effects 0.000 title claims abstract description 7
- 239000003814 drug Substances 0.000 title abstract description 4
- 239000002253 acid Substances 0.000 title description 11
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- 150000002903 organophosphorus compounds Chemical class 0.000 claims abstract description 15
- 244000045947 parasite Species 0.000 claims abstract description 14
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- 239000013543 active substance Substances 0.000 claims description 29
- 150000001875 compounds Chemical class 0.000 claims description 22
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims description 21
- 241000282412 Homo Species 0.000 claims description 20
- 125000002252 acyl group Chemical group 0.000 claims description 20
- 125000000217 alkyl group Chemical group 0.000 claims description 20
- 125000003118 aryl group Chemical group 0.000 claims description 19
- 239000001257 hydrogen Substances 0.000 claims description 19
- 229910052739 hydrogen Inorganic materials 0.000 claims description 19
- 125000000623 heterocyclic group Chemical group 0.000 claims description 18
- 150000002367 halogens Chemical class 0.000 claims description 17
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- 125000003342 alkenyl group Chemical group 0.000 claims description 16
- 125000004432 carbon atom Chemical group C* 0.000 claims description 16
- 150000003839 salts Chemical class 0.000 claims description 15
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- 125000003710 aryl alkyl group Chemical group 0.000 claims description 14
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- 125000000753 cycloalkyl group Chemical group 0.000 claims description 13
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- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 8
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- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 claims description 8
- 125000002947 alkylene group Chemical group 0.000 claims description 8
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims description 8
- 150000003863 ammonium salts Chemical class 0.000 claims description 7
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
- SGKRLCUYIXIAHR-AKNGSSGZSA-N (4s,4ar,5s,5ar,6r,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1=CC=C2[C@H](C)[C@@H]([C@H](O)[C@@H]3[C@](C(O)=C(C(N)=O)C(=O)[C@H]3N(C)C)(O)C3=O)C3=C(O)C2=C1O SGKRLCUYIXIAHR-AKNGSSGZSA-N 0.000 claims description 6
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- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 claims description 5
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 5
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- 150000001408 amides Chemical class 0.000 claims description 5
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- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims description 5
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- XEEQGYMUWCZPDN-DOMZBBRYSA-N (-)-(11S,2'R)-erythro-mefloquine Chemical compound C([C@@H]1[C@@H](O)C=2C3=CC=CC(=C3N=C(C=2)C(F)(F)F)C(F)(F)F)CCCN1 XEEQGYMUWCZPDN-DOMZBBRYSA-N 0.000 claims description 4
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- FSVJFNAIGNNGKK-UHFFFAOYSA-N 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one Chemical compound C1C(C2=CC=CC=C2CC2)N2C(=O)CN1C(=O)C1CCCCC1 FSVJFNAIGNNGKK-UHFFFAOYSA-N 0.000 claims description 4
- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 claims description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 4
- APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 claims description 4
- GNWUOVJNSFPWDD-XMZRARIVSA-M Cefoxitin sodium Chemical group [Na+].N([C@]1(OC)C(N2C(=C(COC(N)=O)CS[C@@H]21)C([O-])=O)=O)C(=O)CC1=CC=CS1 GNWUOVJNSFPWDD-XMZRARIVSA-M 0.000 claims description 4
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- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Oncology (AREA)
- Agronomy & Crop Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843222A DE19843222A1 (de) | 1998-09-22 | 1998-09-22 | Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen |
DE19843222.4 | 1998-09-22 | ||
PCT/EP1999/007054 WO2000016757A2 (fr) | 1998-09-22 | 1999-09-22 | Utilisation de composes organophosphores pour la production de medicaments pour le traitement therapeutique et prophylactique d'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2344867A1 true CA2344867A1 (fr) | 2000-03-30 |
Family
ID=7881691
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002344867A Abandoned CA2344867A1 (fr) | 1998-09-22 | 1999-09-22 | Utilisation des derives de l'acide aminoalkylphosphonique pour la production de medicaments pour le traitement therapeutique et prophylactique dd'infections ou en tant que fongicide, bactericide ou herbicide pour vegetaux |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1115388A1 (fr) |
JP (1) | JP2003520760A (fr) |
KR (1) | KR20010075248A (fr) |
CN (1) | CN1319006A (fr) |
AP (1) | AP2001002106A0 (fr) |
AU (1) | AU5981199A (fr) |
BR (1) | BR9913990A (fr) |
CA (1) | CA2344867A1 (fr) |
DE (1) | DE19843222A1 (fr) |
IL (1) | IL141887A0 (fr) |
NO (1) | NO20011430L (fr) |
OA (1) | OA11655A (fr) |
PL (1) | PL353313A1 (fr) |
SK (1) | SK3932001A3 (fr) |
WO (1) | WO2000016757A2 (fr) |
ZA (1) | ZA200101912B (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9949988B2 (en) | 2014-09-12 | 2018-04-24 | Antibiotx A/S | Antibacterial use of halogenated salicylanilides |
US10463680B2 (en) | 2015-05-29 | 2019-11-05 | UNION therapeutics A/S | Halogenated salicylanilides for treating clostridium infections |
US11419834B2 (en) | 2019-02-25 | 2022-08-23 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1303286B1 (fr) * | 2000-07-11 | 2006-04-26 | Bayer HealthCare AG | Utilisation de souches du virus parapox ovis pour la fabrication de medicaments antiviraux et anticancereux |
WO2002078714A1 (fr) * | 2001-03-30 | 2002-10-10 | Jomaa Pharmaka Gmbh | Formulations gastro-resistantes de composes anti-infectieux, bloquant la voie metabolique de la 2-c-methylerythrose-4, ainsi que leurs sels et esters |
CN105055431B (zh) * | 2015-08-11 | 2018-03-13 | 西南医科大学附属医院 | 一种具有抗结核菌的药物及其应用 |
CN108853106B (zh) * | 2017-05-09 | 2021-02-02 | 中国食品药品检定研究院 | 亚胺吩嗪类化合物作为狂犬病病毒抑制剂的用途 |
KR20210120891A (ko) * | 2020-03-26 | 2021-10-07 | 신풍제약주식회사 | 유행성 rna 바이러스 감염질환의 예방 또는 치료용 약제학적 조성물 |
CN112043707B (zh) * | 2020-09-09 | 2021-07-30 | 武汉珈创生物技术股份有限公司 | 氯法齐明和/或其可药用衍生物在制备抗沙粒病毒药物中的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS542336A (en) * | 1977-06-06 | 1979-01-09 | Meiji Seika Kaisha Ltd | Preventive and remedy for viral diseases |
AU566627B2 (en) * | 1983-08-02 | 1987-10-22 | Omura, S. | Herbicidal antibiotic |
US4693742A (en) * | 1983-12-20 | 1987-09-15 | Rohm And Hass Company | Herbicidal hydroxyamino phosphonic acids and derivatives |
US4846872A (en) * | 1986-08-11 | 1989-07-11 | Fujisawa Pharmaceutical Co., Ltd. | Herbicide |
JP2606296B2 (ja) * | 1988-07-05 | 1997-04-30 | 住友化学工業株式会社 | 除草組成物 |
AU4285896A (en) * | 1994-11-18 | 1996-06-19 | Amira, Inc. | Phosphinic creatine compounds having antiviral activity |
US6680308B1 (en) * | 1998-04-14 | 2004-01-20 | Jomaa Hassan | Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections |
-
1998
- 1998-09-22 DE DE19843222A patent/DE19843222A1/de not_active Withdrawn
-
1999
- 1999-09-22 AU AU59811/99A patent/AU5981199A/en not_active Abandoned
- 1999-09-22 CN CN99811158A patent/CN1319006A/zh active Pending
- 1999-09-22 JP JP2000573718A patent/JP2003520760A/ja active Pending
- 1999-09-22 EP EP99969332A patent/EP1115388A1/fr not_active Withdrawn
- 1999-09-22 SK SK393-2001A patent/SK3932001A3/sk unknown
- 1999-09-22 WO PCT/EP1999/007054 patent/WO2000016757A2/fr not_active Application Discontinuation
- 1999-09-22 CA CA002344867A patent/CA2344867A1/fr not_active Abandoned
- 1999-09-22 OA OA1200100073A patent/OA11655A/en unknown
- 1999-09-22 IL IL14188799A patent/IL141887A0/xx unknown
- 1999-09-22 ZA ZA200101912A patent/ZA200101912B/en unknown
- 1999-09-22 AP APAP/P/2001/002106A patent/AP2001002106A0/en unknown
- 1999-09-22 PL PL99353313A patent/PL353313A1/xx unknown
- 1999-09-22 BR BR9913990-1A patent/BR9913990A/pt not_active Application Discontinuation
- 1999-09-22 KR KR1020017003601A patent/KR20010075248A/ko not_active Application Discontinuation
-
2001
- 2001-03-21 NO NO20011430A patent/NO20011430L/no not_active Application Discontinuation
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9949988B2 (en) | 2014-09-12 | 2018-04-24 | Antibiotx A/S | Antibacterial use of halogenated salicylanilides |
US10758553B2 (en) | 2014-09-12 | 2020-09-01 | UNION therapeutics A/S | Antibacterial use of halogenated salicylanilides |
US11285164B2 (en) | 2014-09-12 | 2022-03-29 | UNION therapeutics A/S | Antibacterial use of halogenated salicylanilides |
US11324761B2 (en) | 2014-09-12 | 2022-05-10 | UNION therapeutics A/S | Antibacterial use of halogenated salicylanilides |
US11331327B2 (en) | 2014-09-12 | 2022-05-17 | UNION therapeutics A/S | Antibacterial use of halogenated salicylanilides |
US10463680B2 (en) | 2015-05-29 | 2019-11-05 | UNION therapeutics A/S | Halogenated salicylanilides for treating clostridium infections |
US10857164B2 (en) | 2015-05-29 | 2020-12-08 | UNION therapeutics A/S | Halogenated salicylanilides for treating Clostridium infections |
US11529361B2 (en) | 2015-05-29 | 2022-12-20 | UNION therapeutics A/S | Halogenated salicylanilides for treating Clostridium infections |
US11419834B2 (en) | 2019-02-25 | 2022-08-23 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide |
Also Published As
Publication number | Publication date |
---|---|
CN1319006A (zh) | 2001-10-24 |
OA11655A (en) | 2004-12-08 |
AP2001002106A0 (en) | 2001-03-31 |
IL141887A0 (en) | 2002-03-10 |
AU5981199A (en) | 2000-04-10 |
WO2000016757A2 (fr) | 2000-03-30 |
BR9913990A (pt) | 2001-10-23 |
JP2003520760A (ja) | 2003-07-08 |
NO20011430D0 (no) | 2001-03-21 |
PL353313A1 (en) | 2003-11-17 |
SK3932001A3 (en) | 2001-08-06 |
NO20011430L (no) | 2001-05-09 |
DE19843222A1 (de) | 2000-03-30 |
ZA200101912B (en) | 2002-03-07 |
KR20010075248A (ko) | 2001-08-09 |
WO2000016757A8 (fr) | 2000-06-29 |
EP1115388A1 (fr) | 2001-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |