DE19834005A1 - Säureadditionssalze von Morphin-Alkaloiden und deren Verwendung - Google Patents

Säureadditionssalze von Morphin-Alkaloiden und deren Verwendung

Info

Publication number
DE19834005A1
DE19834005A1 DE19834005A DE19834005A DE19834005A1 DE 19834005 A1 DE19834005 A1 DE 19834005A1 DE 19834005 A DE19834005 A DE 19834005A DE 19834005 A DE19834005 A DE 19834005A DE 19834005 A1 DE19834005 A1 DE 19834005A1
Authority
DE
Germany
Prior art keywords
acid
substituted
acids
group
morphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19834005A
Other languages
German (de)
English (en)
Inventor
Rainer Dr Hoffmann
Bodo Dr Asmussen
Andreas Dipl Chem Koch
Thomas Dr Hille
Bernd Adam
Rudolf Matusch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Priority to DE19834005A priority Critical patent/DE19834005A1/de
Priority to DK98945312T priority patent/DK1017696T3/da
Priority to HU0003686A priority patent/HUP0003686A3/hu
Priority to PCT/EP1998/005652 priority patent/WO1999015528A1/de
Priority to EP98945312A priority patent/EP1017696B1/de
Priority to PT98945312T priority patent/PT1017696E/pt
Priority to TR2000/00653T priority patent/TR200000653T2/xx
Priority to AT98945312T priority patent/ATE214702T1/de
Priority to NZ503459A priority patent/NZ503459A/en
Priority to JP2000512833A priority patent/JP2001517669A/ja
Priority to IDW20000549A priority patent/ID26296A/id
Priority to MXPA00002658A priority patent/MXPA00002658A/es
Priority to ES98945312T priority patent/ES2174490T3/es
Priority to KR1020007003244A priority patent/KR100555884B1/ko
Priority to AU92666/98A priority patent/AU741434B2/en
Priority to SK432-2000A priority patent/SK4322000A3/sk
Priority to CA002304722A priority patent/CA2304722C/en
Priority to IL134787A priority patent/IL134787A/en
Priority to PL339516A priority patent/PL193321B1/pl
Priority to SI9830180T priority patent/SI1017696T1/xx
Priority to CZ20001048A priority patent/CZ300532B6/cs
Priority to DE59803461T priority patent/DE59803461D1/de
Priority to TW087115805A priority patent/TW576836B/zh
Priority to MYPI98004419A priority patent/MY128486A/en
Publication of DE19834005A1 publication Critical patent/DE19834005A1/de
Priority to NO20001465A priority patent/NO20001465D0/no
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04—Salts; Organic complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19834005A 1997-09-25 1998-07-29 Säureadditionssalze von Morphin-Alkaloiden und deren Verwendung Withdrawn DE19834005A1 (de)

Priority Applications (25)

Application Number Priority Date Filing Date Title
DE19834005A DE19834005A1 (de) 1997-09-25 1998-07-29 Säureadditionssalze von Morphin-Alkaloiden und deren Verwendung
KR1020007003244A KR100555884B1 (ko) 1997-09-25 1998-09-05 모르핀 알칼로이드의 산부가염 및 이의 용도
AU92666/98A AU741434B2 (en) 1997-09-25 1998-09-05 Acidic addition salts of morphine alkaloids and the application thereof
HU0003686A HUP0003686A3 (en) 1997-09-25 1998-09-05 Acidic addition salts of morphine alkaloids and the application thereof
SK432-2000A SK4322000A3 (en) 1997-09-25 1998-09-05 Transdermal or transmucosal composition for administering morphine alkaloids, the application thereof, appropriate compounds and method for their producing
PT98945312T PT1017696E (pt) 1997-09-25 1998-09-05 Sais de adicao de acido de alcaloides de morfina e sua utilizacao
TR2000/00653T TR200000653T2 (tr) 1997-09-25 1998-09-05 Asit katılmış morfin alkoloidlerinin tuzları ve bunların kullanımı.
AT98945312T ATE214702T1 (de) 1997-09-25 1998-09-05 Säureadditionssalze von morphin-alkaloiden und deren verwendung
NZ503459A NZ503459A (en) 1997-09-25 1998-09-05 Organic acid addition salts of morphine alkaloids and use as transdermal or transmucosal agents
JP2000512833A JP2001517669A (ja) 1997-09-25 1998-09-05 モルヒネアルカロイド類の酸添加塩類およびその応用
IDW20000549A ID26296A (id) 1997-09-25 1998-09-05 Garam penambahan asam dari alkaloid morfin dan penggunaannya
MXPA00002658A MXPA00002658A (es) 1997-09-25 1998-09-05 Sales de adicion acida de alcaloides morfinicos y su aplicacion.
ES98945312T ES2174490T3 (es) 1997-09-25 1998-09-05 Sales de adicion de acido de alcaloide de morfina y su utilizacion.
DK98945312T DK1017696T3 (da) 1997-09-25 1998-09-05 Syreadditionssalte af morfin-alkaloider og deres anvendelse
PCT/EP1998/005652 WO1999015528A1 (de) 1997-09-25 1998-09-05 Säureadditionssalze von morphin-alkaloiden und deren verwendung
EP98945312A EP1017696B1 (de) 1997-09-25 1998-09-05 Säureadditionssalze von morphin-alkaloiden und deren verwendung
CA002304722A CA2304722C (en) 1997-09-25 1998-09-05 Acidic addition salts of morphine alkaloids and the application thereof
IL134787A IL134787A (en) 1997-09-25 1998-09-05 Acid addition salts of morphine alkaloids, their preparation and pharmaceutical compositions containing them for trandermal and transmucosal application
PL339516A PL193321B1 (pl) 1997-09-25 1998-09-05 Sole addycyjne alkaloidu morfinowego z kwasem organicznym, sposób ich wytwarzania, ich zastosowanie do sporządzania preparatów, środek poprzezskórny lub poprzezśluzówkowy do aplikowania tych soli oraz takiż środek do zastosowania jako środek do jontoforezy
SI9830180T SI1017696T1 (en) 1997-09-25 1998-09-05 Acidic addition salts of morphine alkaloids and the application thereof
CZ20001048A CZ300532B6 (cs) 1997-09-25 1998-09-05 Adicní soli morfinových alkaloidu s kyselinami a jejich použití
DE59803461T DE59803461D1 (de) 1997-09-25 1998-09-05 Säureadditionssalze von morphin-alkaloiden und deren verwendung
TW087115805A TW576836B (en) 1997-09-25 1998-09-23 Transdermal or transmucosal pharmaceutical composition for administering morphine alkaloid acid addition salts, acid addition salts of morphine alkaloid and organic acid, and method for the production of acid addition salts of morphine alkaloids
MYPI98004419A MY128486A (en) 1997-09-25 1998-09-25 Acid addition salts of morphine alkaloids and the use thereof
NO20001465A NO20001465D0 (no) 1997-09-25 2000-03-21 Syreaddisjonssalt av morfin-alkaloider og deres anvendelse

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742296 1997-09-25
DE19834005A DE19834005A1 (de) 1997-09-25 1998-07-29 Säureadditionssalze von Morphin-Alkaloiden und deren Verwendung

Publications (1)

Publication Number Publication Date
DE19834005A1 true DE19834005A1 (de) 1999-04-01

Family

ID=7843572

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19834005A Withdrawn DE19834005A1 (de) 1997-09-25 1998-07-29 Säureadditionssalze von Morphin-Alkaloiden und deren Verwendung
DE59803461T Expired - Lifetime DE59803461D1 (de) 1997-09-25 1998-09-05 Säureadditionssalze von morphin-alkaloiden und deren verwendung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59803461T Expired - Lifetime DE59803461D1 (de) 1997-09-25 1998-09-05 Säureadditionssalze von morphin-alkaloiden und deren verwendung

Country Status (4)

Country Link
KR (1) KR100555884B1 (ko)
DE (2) DE19834005A1 (ko)
MY (1) MY128486A (ko)
ZA (1) ZA988710B (ko)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1444977A1 (en) * 2003-02-07 2004-08-11 Novosis AG Transdermal therapeutic delivery system with a butenolide
EP1224188B1 (en) * 1999-10-20 2007-01-17 Archimedes Development Limited Nasal delivery composition comprising the methane sulphonate salt of morphine and chitosan
DE102006054732A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224188B1 (en) * 1999-10-20 2007-01-17 Archimedes Development Limited Nasal delivery composition comprising the methane sulphonate salt of morphine and chitosan
EP1444977A1 (en) * 2003-02-07 2004-08-11 Novosis AG Transdermal therapeutic delivery system with a butenolide
DE102006054732A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
DE102006054732B4 (de) * 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
US9089527B2 (en) 2006-11-21 2015-07-28 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising ion pair microreservoirs

Also Published As

Publication number Publication date
MY128486A (en) 2007-02-28
KR100555884B1 (ko) 2006-03-03
ZA988710B (en) 1999-04-01
KR20010030727A (ko) 2001-04-16
DE59803461D1 (de) 2002-04-25

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8127 New person/name/address of the applicant

Owner name: LTS LOHMANN THERAPIE-SYSTEME AG, 56626 ANDERNACH,

8130 Withdrawal