DE68911499T2 - Topisch anzuwendende Zubereitungen und Systeme zur transdermalen Verabreichung enthaltend 1-Isobutyl-1H-imidazo[4,5-c]chinolin-4-amine. - Google Patents

Topisch anzuwendende Zubereitungen und Systeme zur transdermalen Verabreichung enthaltend 1-Isobutyl-1H-imidazo[4,5-c]chinolin-4-amine.

Info

Publication number
DE68911499T2
DE68911499T2 DE68911499T DE68911499T DE68911499T2 DE 68911499 T2 DE68911499 T2 DE 68911499T2 DE 68911499 T DE68911499 T DE 68911499T DE 68911499 T DE68911499 T DE 68911499T DE 68911499 T2 DE68911499 T2 DE 68911499T2
Authority
DE
Germany
Prior art keywords
quinolin
imidazo
isobutyl
amines
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68911499T
Other languages
English (en)
Other versions
DE68911499D1 (de
Inventor
Steven M C O Riker Labora Wick
Helen Jensen C O Riker Schultz
Gregory R C O Riker Lab Nelson
Amit K C O Riker Laborat Mitra
Stephen M C O Riker Labo Berge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Application granted granted Critical
Publication of DE68911499D1 publication Critical patent/DE68911499D1/de
Publication of DE68911499T2 publication Critical patent/DE68911499T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE68911499T 1988-12-15 1989-12-11 Topisch anzuwendende Zubereitungen und Systeme zur transdermalen Verabreichung enthaltend 1-Isobutyl-1H-imidazo[4,5-c]chinolin-4-amine. Expired - Lifetime DE68911499T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28493388A 1988-12-15 1988-12-15

Publications (2)

Publication Number Publication Date
DE68911499D1 DE68911499D1 (de) 1994-01-27
DE68911499T2 true DE68911499T2 (de) 1994-06-30

Family

ID=23092090

Family Applications (2)

Application Number Title Priority Date Filing Date
DE68911499T Expired - Lifetime DE68911499T2 (de) 1988-12-15 1989-12-11 Topisch anzuwendende Zubereitungen und Systeme zur transdermalen Verabreichung enthaltend 1-Isobutyl-1H-imidazo[4,5-c]chinolin-4-amine.
DE19975026C Active DE19975026I2 (de) 1988-12-15 1989-12-11 Topisch anzuwendende Zubereitungen und Systeme zur transdermalen Verabreichung enthaltend 1-Isobutyl-1H-imidazo[4,5-c]chinolin-4-amine.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19975026C Active DE19975026I2 (de) 1988-12-15 1989-12-11 Topisch anzuwendende Zubereitungen und Systeme zur transdermalen Verabreichung enthaltend 1-Isobutyl-1H-imidazo[4,5-c]chinolin-4-amine.

Country Status (14)

Country Link
EP (1) EP0376534B1 (de)
JP (1) JP2915034B2 (de)
KR (1) KR0150445B1 (de)
AU (1) AU631585B2 (de)
CA (1) CA2004597C (de)
DE (2) DE68911499T2 (de)
DK (1) DK176121B1 (de)
ES (1) ES2062043T3 (de)
HK (1) HK1006275A1 (de)
IE (1) IE62569B1 (de)
IL (1) IL92537A (de)
NL (1) NL980042I1 (de)
NZ (1) NZ231655A (de)
ZA (1) ZA899450B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ232740A (en) * 1989-04-20 1992-06-25 Riker Laboratories Inc Solution for parenteral administration comprising a 1h-imidazo(4,5-c) quinolin-4-amine derivative, an acid and a tonicity adjuster
IL105325A (en) * 1992-04-16 1996-11-14 Minnesota Mining & Mfg Immunogen/vaccine adjuvant composition
EP0719561A4 (de) * 1993-08-10 1997-07-30 Fujisawa Pharmaceutical Co Perkutan absorbierend Zubereitung
DE4434775A1 (de) * 1994-09-29 1996-04-04 Beiersdorf Ag Dermatologische Zubereitungen mit einem Gehalt an Fettsäureglyceriden gegen Superinfektionen
US5939090A (en) * 1996-12-03 1999-08-17 3M Innovative Properties Company Gel formulations for topical drug delivery
IT1294748B1 (it) 1997-09-17 1999-04-12 Permatec Tech Ag Formulazione per un dispositivo transdermico
AU776654B2 (en) * 1999-01-08 2004-09-16 3M Innovative Properties Company Formulations and methods for treatment of mucosal associated conditions with an immune response modifier
US8119159B2 (en) 1999-02-22 2012-02-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US7658938B2 (en) 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
EP1392272B1 (de) * 2001-05-11 2014-08-06 Merrion Research III Limited Permeationsverbesserer
EP1390024A4 (de) * 2001-05-11 2010-02-17 Merrion Res Iii Ltd Isostearinsäuresalze als permeationsverbesserer
CN1292751C (zh) * 2002-04-23 2007-01-03 四川大学 皮肤局部用咪喹莫特或其衍生物脂质体及其制备方法和用途
KR20050109562A (ko) * 2003-03-13 2005-11-21 쓰리엠 이노베이티브 프로퍼티즈 컴파니 피부의 질을 개선시키는 방법
KR101191322B1 (ko) 2006-04-07 2012-10-16 메리온 리서치 Ⅲ 리미티드 증진제를 함유하는 고형 경구용 투여 제형
ES2393761T3 (es) 2006-07-14 2012-12-27 Stiefel Research Australia Pty Ltd Espuma farmacéutica de ácido graso
NO343857B1 (no) * 2006-07-18 2019-06-24 Meda Ab Immunresponsmodifiserende skumformuleringer
TW200950799A (en) 2008-05-07 2009-12-16 Merrion Res Iii Ltd Compositions of GnRH related compounds and processes of preparation
US9089484B2 (en) 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
JP2014501784A (ja) 2011-01-07 2014-01-23 メリオン・リサーチ・Ｉｉｉ・リミテッド 経口投与用の鉄の医薬組成物
JP7211704B2 (ja) 2015-01-29 2023-01-24 ノヴォ ノルディスク アー／エス Ｇｌｐ－１アゴニスト及び腸溶コーティングを含む錠剤
ES2940736B2 (es) 2021-11-09 2023-09-19 Ntd Labs S L U Uso combinado de imiquimod y de un hidrolizado de caseina para el tratamiento de condilomas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL73534A (en) * 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
CA1272445A (en) * 1985-02-25 1990-08-07 Yie W. Chien Transdermal pharmaceutical absorption dosage unit and process of pharmaceutical administration
CA1288698C (en) * 1985-08-30 1991-09-10 Yie W. Chien Transdermal anti-anginal pharmaceutical dosage

Also Published As

Publication number Publication date
IE893888L (en) 1990-06-15
CA2004597C (en) 2000-02-08
EP0376534A1 (de) 1990-07-04
NL980042I1 (nl) 1999-02-01
DK613889A (da) 1990-06-16
EP0376534B1 (de) 1993-12-15
IE62569B1 (en) 1995-02-08
KR900009084A (ko) 1990-07-02
DK176121B1 (da) 2006-09-11
IL92537A0 (en) 1990-08-31
DK613889D0 (da) 1989-12-06
IL92537A (en) 1994-04-12
DE19975026I2 (de) 2010-07-08
ES2062043T3 (es) 1994-12-16
ZA899450B (en) 1990-09-26
KR0150445B1 (ko) 1998-10-15
AU631585B2 (en) 1992-12-03
JPH02282327A (ja) 1990-11-19
NZ231655A (en) 1992-06-25
DE68911499D1 (de) 1994-01-27
JP2915034B2 (ja) 1999-07-05
HK1006275A1 (en) 1999-02-19
CA2004597A1 (en) 1990-06-15
AU4670689A (en) 1990-06-21

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