MY128486A - Acid addition salts of morphine alkaloids and the use thereof - Google Patents

Acid addition salts of morphine alkaloids and the use thereof

Info

Publication number
MY128486A
MY128486A MYPI98004419A MYPI9804419A MY128486A MY 128486 A MY128486 A MY 128486A MY PI98004419 A MYPI98004419 A MY PI98004419A MY PI9804419 A MYPI9804419 A MY PI9804419A MY 128486 A MY128486 A MY 128486A
Authority
MY
Malaysia
Prior art keywords
substituted
acids
group
acid addition
optionally
Prior art date
Application number
MYPI98004419A
Inventor
Rainer Dr Hoffmann
Bodo Dr Asmussen
Andreas Koch
Thomas Hille
Bern Adam
Rudolf Matusch
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of MY128486A publication Critical patent/MY128486A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04—Salts; Organic complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A SUBSTANCE CONSISTING OF AN ACID ADDITION SALT OF A MORPHINE ALKALOID AND AN ORGANIC ACID IS PROVIDED.THE ORGANIC ACID IS SELECTED FROM :- MONOESTERS OF C3- TO C16- DICARBOXYLIC ACIDS WITH MONO-HYDRIC C1- TO C4- ALCOHOLS,- C2-TO C16-SULFONIC ACIDS, - SUBSTITUTED BENZOIC ACIDS, SELECTED FROM THE GROUP OF HALOGEN,HYDROXY, ALKYL, HYDROXYALKYL, ALKOXYALKYL AND/OR ALKOXY-SUBSTITUTED BENZOIC ACID, AS WELL AS OF THE AMINOSUBSTITUTED BENZOIC ACIDS, WHICH MAY OPTIONALLY BE ALKYLATED AT THE N ATOM,- SUBSTITUTED OR NON-SUBSTITUTED 5-RING OR 6-RING HETROCYCLES COMPRISING AT LEAST ONE N OR S ATOM AND HAVING A CARBOXYL GROUP FUNCTION, - SATURATED OR UNSATURATED, OPTIONALLY SUBSTITUTED, OXOCARBOXYLIC ACIDS HAVING 5 TO 10 C ATOMS, - PHENYL-SUBSTITUTED OR PHENOXY-SUBSTITUTED SATURATED C2- TO C4-CARBOXYLIC ACIDS.@- ALIPHATIC, AROMATIC OR HETEROCYCLIC C2- TO C12-AMINO ACIDS, WHEREIN ONE AMINO GROUP IS SUBSTITUTED WITH AN-OPTIONALLY SUBSTITUTED - C2- TO C6- ALKANOYL GROUP OR AN-OPTIONALLY SUBSTITUTED-BENZOYL GROUP.
MYPI98004419A 1997-09-25 1998-09-25 Acid addition salts of morphine alkaloids and the use thereof MY128486A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742296 1997-09-25
DE19834005A DE19834005A1 (en) 1997-09-25 1998-07-29 Acid addition salts of morphine alkaloids and their use

Publications (1)

Publication Number Publication Date
MY128486A true MY128486A (en) 2007-02-28

Family

ID=7843572

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI98004419A MY128486A (en) 1997-09-25 1998-09-25 Acid addition salts of morphine alkaloids and the use thereof

Country Status (4)

Country Link
KR (1) KR100555884B1 (en)
DE (2) DE19834005A1 (en)
MY (1) MY128486A (en)
ZA (1) ZA988710B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9924797D0 (en) * 1999-10-20 1999-12-22 West Pharm Serv Drug Res Ltd Compound
DE10305137A1 (en) * 2003-02-07 2004-08-26 Novosis Ag Transdermal therapeutic delivery systems with a butenolide
DE102006054732B4 (en) * 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with ion-pair microreservoirs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids

Also Published As

Publication number Publication date
ZA988710B (en) 1999-04-01
DE59803461D1 (en) 2002-04-25
KR20010030727A (en) 2001-04-16
DE19834005A1 (en) 1999-04-01
KR100555884B1 (en) 2006-03-03

Similar Documents

Publication Publication Date Title
EP0786926A3 (en) Light-emitting material for organo-electroluminescence device and organo-electroluminescence devive for which the light-emitting material is adapted
JPS5353691A (en) 3,7-di-substituted-3-cephem-4 carboxylic acid derivatives, their salts andtheir preparation
IL139960A0 (en) Macrocylic analogs and methods of their use and preparation
EP0628311A4 (en) Antidepressant.
CA2039056A1 (en) 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
JPS52108997A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and their salts and their preparation
BG103863A (en) Indazolamide compounds as serotoninergic forms
ES2117426T3 (en) CRYSTALLINE FORM OF ANHYDRAUS SALT COMPOSED OF ACIDS 7 - ((1A, 5A, 6A) -6-AMINO-3-AZABICICLO (3.1.0.) HEX-3-IL) -6-FLUORO-1- (2, 4-DIFLUOROFENIL) -1,4-DIHIDRO-4-OXO-1,8-NAFTIRIDINA-3-CARBOXILICO AND METANOSULFONICO.
MY128486A (en) Acid addition salts of morphine alkaloids and the use thereof
EP0661972A4 (en) Use of spiperone or spiperone derivatives as immunosuppressant agents.
YU86792A (en) SPARFLOXACIN SOLUTION, ITS PREPARATION AND ARE SPARFLOXACINE AS A SOLUTION COMPONENT
ES2162856T3 (en) SEROTONINERGIC ERGOLINE DERIVATIVES.
ES2132245T3 (en) DERIVATIVES OF 1-AZAADAMANTHANE AS 5-HT AGONISTS OR ANTAGONISTS.
IL134787A0 (en) Acid addition salts of morphine alkaloids and compositions containing the same
EP0844241A4 (en) Inhibitor for narcotic analgetic dependence/resistance acquisition
EP1674454A4 (en) SUBSTITUTED 2-AMINO- 1,2,4 TRIAZOLO 1,5-a PYRIMIDINE DERIVATIVE AND USE THEREOF
BG103986A (en) Derivatives of pyrrolidinecarboxylic acids as endotheline antagonists
NO933115D0 (en) 3-oxadiazolyl-1,6-naphthyridine
ES8107222A1 (en) 17-Cycloalkylmethyl-6-methylene-morphinane-derivatives.
EP1083175A3 (en) Triazole derivatives having antifungal activity
IL59992A0 (en) Morphinan-6-one derivatives and their use as medicines
JPS52156892A (en) 7-(n-acylamino-alpha-arylacetamido)cephalosporins
EP0325428A3 (en) 6' carbamate esters of zearalanol and its derivatives
JPS5616442A (en) Preparation of 2-substituted-3-oxo-cyclopentylacetic acid ester
IE780742L (en) Isoxazolylmethyl-benzomorphanes