DE19720761A1 - Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung - Google Patents

Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung

Info

Publication number
DE19720761A1
DE19720761A1 DE19720761A DE19720761A DE19720761A1 DE 19720761 A1 DE19720761 A1 DE 19720761A1 DE 19720761 A DE19720761 A DE 19720761A DE 19720761 A DE19720761 A DE 19720761A DE 19720761 A1 DE19720761 A1 DE 19720761A1
Authority
DE
Germany
Prior art keywords
secretion
proteins
attenuated
salmonella
fragments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19720761A
Other languages
German (de)
English (en)
Inventor
Peter Dr Donner
Werner Prof Goebel
Andreas Dr Demuth
Ivaylo Dr Gentschev
Juergen Dr Hess
Stefan Prof Kaufmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to DE19720761A priority Critical patent/DE19720761A1/de
Priority to CN98804817A priority patent/CN1255067A/zh
Priority to EEP199900516A priority patent/EE9900516A/xx
Priority to EP98929286A priority patent/EP1015023A1/de
Priority to SK1517-99A priority patent/SK151799A3/sk
Priority to PL98336786A priority patent/PL336786A1/xx
Priority to JP54774098A priority patent/JP2002501507A/ja
Priority to PCT/EP1998/002679 priority patent/WO1998050067A2/de
Priority to KR1019997010208A priority patent/KR20010012257A/ko
Priority to IL13252198A priority patent/IL132521A0/xx
Priority to AU79107/98A priority patent/AU7910798A/en
Priority to HU0002752A priority patent/HUP0002752A2/hu
Priority to TR1999/02671T priority patent/TR199902671T2/xx
Priority to BR9809244-8A priority patent/BR9809244A/pt
Priority to CA002288602A priority patent/CA2288602A1/en
Publication of DE19720761A1 publication Critical patent/DE19720761A1/de
Priority to IS5199A priority patent/IS5199A/is
Priority to BG103850A priority patent/BG103850A/xx
Priority to NO995429A priority patent/NO995429L/no
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0006Contraceptive vaccins; Vaccines against sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE19720761A 1997-05-07 1997-05-07 Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung Withdrawn DE19720761A1 (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE19720761A DE19720761A1 (de) 1997-05-07 1997-05-07 Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung
IL13252198A IL132521A0 (en) 1997-05-07 1998-05-07 Use of a secretion vector for birth control by oral vaccination
AU79107/98A AU7910798A (en) 1997-05-07 1998-05-07 Use or a secretion vector for fertility control by oral vaccination
EP98929286A EP1015023A1 (de) 1997-05-07 1998-05-07 Verwendung eines sekretionsvektors zur fertilitätskontrolle durch orale vakzinierung
SK1517-99A SK151799A3 (en) 1997-05-07 1998-05-07 Use or a secretion vector for fertility control by oral vaccination
PL98336786A PL336786A1 (en) 1997-05-07 1998-05-07 Application of a secretion vector in controlling fertility by means of an orally administered vaccine
JP54774098A JP2002501507A (ja) 1997-05-07 1998-05-07 出生調節用経口ワクチン接種における分泌ベクターの使用
PCT/EP1998/002679 WO1998050067A2 (de) 1997-05-07 1998-05-07 Verwendung eines sekretionsvektors zur fertilitätskontrolle durch orale vakzinierung
KR1019997010208A KR20010012257A (ko) 1997-05-07 1998-05-07 분비 벡터의 경구 백신접종에 의한 수정 조절 용도
CN98804817A CN1255067A (zh) 1997-05-07 1998-05-07 一种通过口服接种用于节育的分泌型载体的应用
EEP199900516A EE9900516A (et) 1997-05-07 1998-05-07 Sekretsioonivektori kasutamine viljastuskontrolliks peroraalse vaktsineerimise abil
HU0002752A HUP0002752A2 (hu) 1997-05-07 1998-05-07 Egy szekréciós vektor alkalmazása termékenység-szabályozásra orális vakcinálással
TR1999/02671T TR199902671T2 (xx) 1997-05-07 1998-05-07 Bir salg�lama vekt�r�n�n do�um kontrol�nde oral vaksinasyon vas�tas�yla kullan�l���.
BR9809244-8A BR9809244A (pt) 1997-05-07 1998-05-07 Aplicação de um vetor de secreção para o controle da fertilidade mediante vacinação oral
CA002288602A CA2288602A1 (en) 1997-05-07 1998-05-07 Use of a secretion vector for fertility control by oral vaccination
IS5199A IS5199A (is) 1997-05-07 1999-09-28 Notkun á seytisgenaferju fyrir frjósemisstýringu með ónæmingu um munn
BG103850A BG103850A (en) 1997-05-07 1999-11-02 The application of secreting vector for fertility control by peroral vaccination
NO995429A NO995429L (no) 1997-05-07 1999-11-05 Anvendelse av en sekresjonsvektor for fertilitetskontroll ved oral vaksinasjon

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19720761A DE19720761A1 (de) 1997-05-07 1997-05-07 Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung

Publications (1)

Publication Number Publication Date
DE19720761A1 true DE19720761A1 (de) 1998-11-12

Family

ID=7829783

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19720761A Withdrawn DE19720761A1 (de) 1997-05-07 1997-05-07 Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung

Country Status (18)

Country Link
EP (1) EP1015023A1 (xx)
JP (1) JP2002501507A (xx)
KR (1) KR20010012257A (xx)
CN (1) CN1255067A (xx)
AU (1) AU7910798A (xx)
BG (1) BG103850A (xx)
BR (1) BR9809244A (xx)
CA (1) CA2288602A1 (xx)
DE (1) DE19720761A1 (xx)
EE (1) EE9900516A (xx)
HU (1) HUP0002752A2 (xx)
IL (1) IL132521A0 (xx)
IS (1) IS5199A (xx)
NO (1) NO995429L (xx)
PL (1) PL336786A1 (xx)
SK (1) SK151799A3 (xx)
TR (1) TR199902671T2 (xx)
WO (1) WO1998050067A2 (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989160B2 (en) * 2002-03-19 2006-01-24 Council Of Scientific And Industrial Research Therapeutic/edible compositions comprising herbal ingredients and methods for treating hyperglycemia

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10206325A1 (de) * 2002-02-14 2003-09-04 Medinnova Ges Med Innovationen Ummantelter Mikroorganismus
WO2006121165A1 (ja) * 2005-05-12 2006-11-16 Ajinomoto Co., Inc. タンパク質の製造法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69131014T2 (de) * 1990-11-21 1999-10-07 Washington University, St. Louis Rekombinante avirulente salmonella antifruchtbarkeitsimpfstoffe
US5480799A (en) * 1993-12-10 1996-01-02 The University Of North Carolina At Chapel Hill Sperm antigen corresponding to a sperm zona binding protein autoantigenic epitope

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989160B2 (en) * 2002-03-19 2006-01-24 Council Of Scientific And Industrial Research Therapeutic/edible compositions comprising herbal ingredients and methods for treating hyperglycemia

Also Published As

Publication number Publication date
WO1998050067A2 (de) 1998-11-12
WO1998050067A3 (de) 2000-06-29
NO995429L (no) 2000-01-07
EE9900516A (et) 2000-06-15
BR9809244A (pt) 2000-06-27
KR20010012257A (ko) 2001-02-15
JP2002501507A (ja) 2002-01-15
EP1015023A1 (de) 2000-07-05
CN1255067A (zh) 2000-05-31
IS5199A (is) 1999-09-28
HUP0002752A2 (hu) 2000-12-28
BG103850A (en) 2000-05-31
WO1998050067A9 (de) 1999-03-25
NO995429D0 (no) 1999-11-05
PL336786A1 (en) 2000-07-17
CA2288602A1 (en) 1998-11-12
IL132521A0 (en) 2001-03-19
SK151799A3 (en) 2000-06-12
TR199902671T2 (xx) 2000-09-21
AU7910798A (en) 1998-11-27

Similar Documents

Publication Publication Date Title
DE69331733T2 (de) Rekombinantes vielwertiges m-protein-vakzin
DE69131014T2 (de) Rekombinante avirulente salmonella antifruchtbarkeitsimpfstoffe
DE69024652T2 (de) Expression von tetanustoxinfragment c
DE68925138T2 (de) Verfahren zur Herstellung von Proteinen durch Verwendung von CKS-Fusionsproteinen
DE68924162T2 (de) Stressproteine und verwendungen dafür.
DE69836588T2 (de) Tuberkulose impfstoff
DE69430246T2 (de) Rekombinante tetc-fusionsprotein enthaltene impfstoffzusammensetzungen
DE69331269T2 (de) Verfahren zur herstellung von antikörpern
WO1991013157A1 (en) Shuttle plasmid for escherichia coli and mycobacteria
DE69034075T2 (de) Rekombinantes poxvirus und streptokokken enthaltend ein m-protein
JPH06206900A (ja) 融合タンパク質
DE3751727T2 (de) Polypeptide zur verwendung bei der diagnose von mycoplasmainfektionen bei schweinen, sowie rekombinant-dns-verfahren zur herstellung derselben
DE69434661T2 (de) An die periplasmatische Membran gebundenes System zur Ermittlung von Protein-Protein Interaktionen
Magaña-Ortíz et al. Extracellular expression in Aspergillus niger of an antibody fused to Leishmania sp. antigens
DE19720761A1 (de) Verfahren zur Synthese und Sekretion von zur Kontrazeption geeigneter Proteine oder Proteinfragmente durch attenuierte Salmonellen oder einen anderen Gram-negativen attenuierten Impfstamm zur Erzeugung einer oralen Vakzinierung
DE69836520T2 (de) Clostridium perfringens Impfstoff
DE4005874A1 (de) Traegergebundene rekombinante proteine, verfahren zur herstellung und verwendung als immunogene und vakzine
DE60021719T2 (de) Mikrobielle proteinexpressionssysteme
IT1244706B (it) Plasmide pctd isolato da chlamydia trachomatis serotipo d, suoi geni e proteine da essi codificate; plasmidi ricombinanti per l'espressionedi detti geni in sistemi eterologhi come proteine ricombinanti di fusione, preparazione di dette proteine ricombinanti e loro uso nella formulazione di vaccini e/o diagnostici
WO2005085417A2 (de) Bakterielles system zum proteintransport in eukaryontische zellen
EP0627006B1 (de) Hybrid-dna, die eine untereinheit eines bakteriellen toxins mit einer haemolysin kodiert
Zueco et al. Protein A fusion vectors for use in combination with pEX vectors in the production and affinity purification of specific antibodies
AU1471202A (en) Use of a secretion vector for fertility control by oral vaccination
EP1144590A1 (de) Kompartimentierung von rekombinanten polypeptiden in wirtszellen
DE69009883T2 (de) Thermo-induzierbare Expression von heterologen Genen in Bacillus subtilis und Mittel und Verfahren zu deren Ausführung.

Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8130 Withdrawal