DE69024652T2 - Expression von tetanustoxinfragment c - Google Patents

Expression von tetanustoxinfragment c

Info

Publication number
DE69024652T2
DE69024652T2 DE69024652T DE69024652T DE69024652T2 DE 69024652 T2 DE69024652 T2 DE 69024652T2 DE 69024652 T DE69024652 T DE 69024652T DE 69024652 T DE69024652 T DE 69024652T DE 69024652 T2 DE69024652 T2 DE 69024652T2
Authority
DE
Germany
Prior art keywords
expression
tetanustox
infragment
tetanus toxin
mature fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69024652T
Other languages
English (en)
Other versions
DE69024652D1 (de
Inventor
Neil Fairweather
Andrew Makoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Pharma Ltd
Original Assignee
Evans Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evans Medical Ltd filed Critical Evans Medical Ltd
Application granted granted Critical
Publication of DE69024652D1 publication Critical patent/DE69024652D1/de
Publication of DE69024652T2 publication Critical patent/DE69024652T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69024652T 1989-06-20 1990-06-20 Expression von tetanustoxinfragment c Expired - Lifetime DE69024652T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898914122A GB8914122D0 (en) 1989-06-20 1989-06-20 Polypeptide expression
PCT/GB1990/000943 WO1990015871A1 (en) 1989-06-20 1990-06-20 Expression of tetanus toxin fragment c

Publications (2)

Publication Number Publication Date
DE69024652D1 DE69024652D1 (de) 1996-02-15
DE69024652T2 true DE69024652T2 (de) 1996-05-15

Family

ID=10658724

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69024652T Expired - Lifetime DE69024652T2 (de) 1989-06-20 1990-06-20 Expression von tetanustoxinfragment c

Country Status (9)

Country Link
US (1) US5443966A (de)
EP (1) EP0478602B1 (de)
JP (1) JP2981286B2 (de)
AT (1) ATE132532T1 (de)
DE (1) DE69024652T2 (de)
DK (1) DK0478602T3 (de)
ES (1) ES2084030T3 (de)
GB (1) GB8914122D0 (de)
WO (1) WO1990015871A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601826A (en) * 1989-06-30 1997-02-11 The United States Of America As Represented By The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
GB9209118D0 (en) 1992-04-28 1992-06-10 Sb 120 Amsterdam Bv Vaccine compositions
AU4545393A (en) * 1992-06-30 1994-01-24 United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Peptide which produces protective immunity against tetanus
CA2141427C (en) 1992-07-31 2008-07-22 Mohammed Anjam Khan Expression of recombinant fusion proteins in attenuated bacteria
GB9401787D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccine compositions
EP0876401B1 (de) * 1996-01-22 2007-06-13 Curis, Inc. Methoden zur herstellung von op-1 morphogen analoge
US20030185792A1 (en) * 1996-01-22 2003-10-02 Curis, Inc. Morphogen analogs of bone morphogenic proteins
CA2216425C (en) 1996-03-23 2003-08-12 The Research Foundation For Microbial Diseases Of Osaka University Tetanus toxin functional fragment antigen and tetanus vaccine
US5958469A (en) * 1997-05-14 1999-09-28 Eastman Kodak Company Method for fabricating tools for molding diffractive surfaces on optical lenses
US7923216B2 (en) 1997-08-14 2011-04-12 Institut Pasteur In vivo modulation of neuronal transport
EP1681300A1 (de) * 1997-08-14 2006-07-19 Institut Pasteur Hybdride Tetanustoxinproteine die rückwirkend und transsynaptisch ins ZNS migrieren
US20100081197A1 (en) * 1997-08-14 2010-04-01 Sylvie Roux In vivo modulation of neuronal transport
EP1296715B2 (de) 2000-06-29 2015-12-23 SmithKline Beecham Biologicals S.A. Multivalente impfstoffzusammensetzung
GB0108364D0 (en) 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
US20070105799A1 (en) * 2002-09-10 2007-05-10 Vical Incorporated Codon-optimized polynucleotide-based vaccines against Bacillus anthracis infection
BRPI0411854A (pt) * 2003-06-23 2006-08-29 Baxter Int veìculos protéicos para vacinas
US20070092449A1 (en) * 2005-04-05 2007-04-26 Rafael Vazquez-Martinez Methods for direct visualization of active synapses
EP1790358A1 (de) * 2005-11-23 2007-05-30 Université de Reims Champagne-Ardennes Proteinkonstrukte designed zum Targeting und Lyse von Zellen
PL2066344T3 (pl) 2006-09-07 2011-10-31 Glaxosmithkline Biologicals Sa Skojarzona szczepionka zawierająca inaktywowany wirus polio
EP2142211A1 (de) 2007-05-02 2010-01-13 GlaxoSmithKline Biologicals S.A. Impfstoff
EP2553102B1 (de) 2010-03-30 2015-12-09 Pfenex Inc. Hochleistungs-expression rekombinanter toxinproteine
EP2569018A4 (de) 2010-05-14 2013-12-04 Philadelphia Children Hospital Humanisiertes ttc und verfahren zu seiner verwendung
GB201105981D0 (en) 2011-04-08 2011-05-18 Glaxosmithkline Biolog Sa Novel process
EP2788021B1 (de) 2011-12-09 2017-01-18 Bavarian Nordic A/S Pockenvirus-vektor zur expression von bakteriellen antigen, welche mit tetanus toxin fragment c verbunden sind
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
NZ630868A (en) 2013-03-08 2017-02-24 Janssen Vaccines & Prevention Bv Acellular pertussis vaccine
KR20170044093A (ko) 2014-07-02 2017-04-24 스페리움 바이오메드 에스.엘. 무독성 파상풍 독소 c 단편(ttc)을 사용하여 근육량을 증가시키는 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355094C3 (de) * 1973-11-03 1979-05-23 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tetanus-Impfstoffs
GB8516442D0 (en) * 1985-06-28 1985-07-31 Wellcome Found Cloned antigen

Also Published As

Publication number Publication date
US5443966A (en) 1995-08-22
DE69024652D1 (de) 1996-02-15
ATE132532T1 (de) 1996-01-15
EP0478602B1 (de) 1996-01-03
DK0478602T3 (da) 1996-02-05
GB8914122D0 (en) 1989-08-09
JP2981286B2 (ja) 1999-11-22
JPH04506005A (ja) 1992-10-22
ES2084030T3 (es) 1996-05-01
EP0478602A1 (de) 1992-04-08
WO1990015871A1 (en) 1990-12-27

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Legal Events

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