DK0478602T3 - Ekspression af tetanus toxin fragment C - Google Patents

Ekspression af tetanus toxin fragment C

Info

Publication number
DK0478602T3
DK0478602T3 DK90909052.4T DK90909052T DK0478602T3 DK 0478602 T3 DK0478602 T3 DK 0478602T3 DK 90909052 T DK90909052 T DK 90909052T DK 0478602 T3 DK0478602 T3 DK 0478602T3
Authority
DK
Denmark
Prior art keywords
tetanus toxin
expression
toxin fragment
fragment
mature fragment
Prior art date
Application number
DK90909052.4T
Other languages
English (en)
Inventor
Neil Fraser Fairweather
Andrew Joseph Makoff
Original Assignee
Evans Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evans Medical Ltd filed Critical Evans Medical Ltd
Application granted granted Critical
Publication of DK0478602T3 publication Critical patent/DK0478602T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK90909052.4T 1989-06-20 1990-06-20 Ekspression af tetanus toxin fragment C DK0478602T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898914122A GB8914122D0 (en) 1989-06-20 1989-06-20 Polypeptide expression

Publications (1)

Publication Number Publication Date
DK0478602T3 true DK0478602T3 (da) 1996-02-05

Family

ID=10658724

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90909052.4T DK0478602T3 (da) 1989-06-20 1990-06-20 Ekspression af tetanus toxin fragment C

Country Status (9)

Country Link
US (1) US5443966A (da)
EP (1) EP0478602B1 (da)
JP (1) JP2981286B2 (da)
AT (1) ATE132532T1 (da)
DE (1) DE69024652T2 (da)
DK (1) DK0478602T3 (da)
ES (1) ES2084030T3 (da)
GB (1) GB8914122D0 (da)
WO (1) WO1990015871A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601826A (en) * 1989-06-30 1997-02-11 The United States Of America As Represented By The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
GB9209118D0 (en) * 1992-04-28 1992-06-10 Sb 120 Amsterdam Bv Vaccine compositions
AU4545393A (en) * 1992-06-30 1994-01-24 United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Peptide which produces protective immunity against tetanus
KR950702635A (ko) 1992-07-31 1995-07-29 크리스틴 헬렌 수덴 감쇠 박테리아에서 재조합 융합 단백질의 발현(Expression of recombinant fusion proteins in attenuated bacteria)
GB9401787D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccine compositions
JP2000501744A (ja) * 1996-01-22 2000-02-15 クリエイティブ バイオモレキゥルズ，インコーポレーテッド モルホゲン類似体およびその製法
US20030185792A1 (en) * 1996-01-22 2003-10-02 Curis, Inc. Morphogen analogs of bone morphogenic proteins
CA2216425C (en) * 1996-03-23 2003-08-12 The Research Foundation For Microbial Diseases Of Osaka University Tetanus toxin functional fragment antigen and tetanus vaccine
US5958469A (en) * 1997-05-14 1999-09-28 Eastman Kodak Company Method for fabricating tools for molding diffractive surfaces on optical lenses
US7923216B2 (en) * 1997-08-14 2011-04-12 Institut Pasteur In vivo modulation of neuronal transport
US20100081197A1 (en) * 1997-08-14 2010-04-01 Sylvie Roux In vivo modulation of neuronal transport
PT1049712E (pt) * 1997-08-14 2007-04-30 Pasteur Institut Proteínas híbridas da toxina do tétano que migram retrogradamente e trans - sinapticamente para o snc
AP1695A (en) 2000-06-29 2006-12-17 Glaxosmithkline Biologicals Sa Multivalent vaccine composition.
GB0108364D0 (en) 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
AU2003278776A1 (en) * 2002-09-10 2004-04-30 Vical Incorporated Codon-optimized polynucleotide-based vaccines against bacillus anthracis infection
JP4764820B2 (ja) * 2003-06-23 2011-09-07 バクスター・インターナショナル・インコーポレイテッド ワクチン用担体タンパク質
US20070092449A1 (en) * 2005-04-05 2007-04-26 Rafael Vazquez-Martinez Methods for direct visualization of active synapses
EP1790358A1 (en) * 2005-11-23 2007-05-30 Université de Reims Champagne-Ardennes Protein constructs designed for targeting and lysis of cells
MX2009002560A (es) 2006-09-07 2009-03-20 Glaxosmithkline Biolog Sa Vacuna.
EA201490303A1 (ru) 2007-05-02 2014-05-30 Глаксосмитклайн Байолоджикалс С.А. Вакцина
NZ602958A (en) 2010-03-30 2014-07-25 Pfenex Inc High level expression of recombinant toxin proteins
WO2011143557A2 (en) 2010-05-14 2011-11-17 The Children's Hospital Of Philadelphia Humanized ttc and methods of use thereof
GB201105981D0 (en) 2011-04-08 2011-05-18 Glaxosmithkline Biolog Sa Novel process
DK2788021T3 (da) 2011-12-09 2017-04-10 Bavarian Nordic As Poxvirusvektor til ekspression af bakterielle antigener, der er koblet til tetanustoksinfragment c
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US8916173B2 (en) 2013-03-08 2014-12-23 Crucell Holland B.V. Acellular pertussis vaccine
JP2017521408A (ja) 2014-07-02 2017-08-03 スフェリウム バイオメッド エス．エル． 無毒性破傷風毒素ｃフラグメント（ｔｔｃ）を使用して筋量を増加させる方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355094C3 (de) * 1973-11-03 1979-05-23 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tetanus-Impfstoffs
GB8516442D0 (en) * 1985-06-28 1985-07-31 Wellcome Found Cloned antigen

Also Published As

Publication number Publication date
US5443966A (en) 1995-08-22
ES2084030T3 (es) 1996-05-01
GB8914122D0 (en) 1989-08-09
EP0478602A1 (en) 1992-04-08
JPH04506005A (ja) 1992-10-22
JP2981286B2 (ja) 1999-11-22
EP0478602B1 (en) 1996-01-03
ATE132532T1 (de) 1996-01-15
DE69024652T2 (de) 1996-05-15
DE69024652D1 (de) 1996-02-15
WO1990015871A1 (en) 1990-12-27

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