ATE93271T1 - Vakzine. - Google Patents

Vakzine.

Info

Publication number
ATE93271T1
ATE93271T1 AT90312870T AT90312870T ATE93271T1 AT E93271 T1 ATE93271 T1 AT E93271T1 AT 90312870 T AT90312870 T AT 90312870T AT 90312870 T AT90312870 T AT 90312870T AT E93271 T1 ATE93271 T1 AT E93271T1
Authority
AT
Austria
Prior art keywords
vaccine
production
tetanus toxin
toxin fragment
fragment
Prior art date
Application number
AT90312870T
Other languages
English (en)
Inventor
Andrew Joseph Makoff
Michael Anthony Romanos
Jeffrey John The Wellcom Clare
Neil Fraser Fairweather
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898926832A external-priority patent/GB8926832D0/en
Priority claimed from GB909006097A external-priority patent/GB9006097D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE93271T1 publication Critical patent/ATE93271T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT90312870T 1989-11-28 1990-11-27 Vakzine. ATE93271T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898926832A GB8926832D0 (en) 1989-11-28 1989-11-28 Vaccines
GB909006097A GB9006097D0 (en) 1990-03-17 1990-03-17 Vaccines
EP90312870A EP0430645B1 (de) 1989-11-28 1990-11-27 Vakzine

Publications (1)

Publication Number Publication Date
ATE93271T1 true ATE93271T1 (de) 1993-09-15

Family

ID=26296269

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90312870T ATE93271T1 (de) 1989-11-28 1990-11-27 Vakzine.

Country Status (7)

Country Link
US (2) US5389540A (de)
EP (1) EP0430645B1 (de)
JP (1) JP3003211B2 (de)
AT (1) ATE93271T1 (de)
DE (1) DE69002817T2 (de)
DK (1) DK0430645T3 (de)
ES (1) ES2058821T3 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601826A (en) * 1989-06-30 1997-02-11 The United States Of America As Represented By The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
WO1994000487A1 (en) * 1992-06-30 1994-01-06 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
JP3633933B2 (ja) * 1992-07-31 2005-03-30 アカンビス、リサーチ、リミテッド 弱毒化細菌における組換え融合タンパク質の発現
CA2101610A1 (en) * 1992-08-07 1994-02-08 William D. Prevatt Production of bacillus entomotoxins in methylotrophic yeast
US7214787B1 (en) * 1993-09-21 2007-05-08 United States Of America As Represented By The Secretary Of The Army Recombinant vaccine against botulinum neurotoxin
WO1997035612A1 (fr) 1996-03-23 1997-10-02 The Research Foundation For Microbial Diseases Of Osaka University Antigene a fragment fonctionnel de la toxine du tetanos, et vaccin contre le tetanos
EP0912726A4 (de) 1996-05-10 2001-07-18 Phylomed Corp Verfahren zur oxidation von disulfid-bindungen durch gebrauch von ozon
US7217860B1 (en) 1999-09-21 2007-05-15 Rutgers, The State University Of New Jersey Site-specific recombination system to manipulate the plastid genome of higher plants
US7186560B2 (en) 1999-09-21 2007-03-06 Rutgers, The State University Of New Jersey High level expression of immunogenic proteins in the plastids of higher plants
AU2002252525A1 (en) 2001-03-29 2002-10-15 Rutgers, The University Of New Jersey Integrases for the insertion of heterologous nucleic acids into the plastid genome
GB0205376D0 (en) * 2002-03-07 2002-04-24 Royal Holloway University Of L Spore germination
EP1356820A1 (de) * 2002-04-26 2003-10-29 Institut National De La Sante Et De La Recherche Medicale (Inserm) DNA-Impfstoff kombiniert mit einen Apoptoneauslöser von Tumorzellen
AU2003278776A1 (en) * 2002-09-10 2004-04-30 Vical Incorporated Codon-optimized polynucleotide-based vaccines against bacillus anthracis infection
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
US8841511B2 (en) 2003-03-03 2014-09-23 Rutgers, The State University Of New Jersey Removal of plastid sequences by transiently expressed site-specific recombinases
US8080642B2 (en) * 2003-05-16 2011-12-20 Vical Incorporated Severe acute respiratory syndrome DNA compositions and methods of use
EP1774017B1 (de) 2004-07-26 2013-05-15 Pfenex Inc. Verfahren zur verbesserten proteinexpression durch strain-engineering
WO2007121467A2 (en) 2006-04-18 2007-10-25 Rutgers, The State University Of New Jersey Compositions and methods for increasing transgene expression in the plastids of higher plants
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
EP2553102B1 (de) 2010-03-30 2015-12-09 Pfenex Inc. Hochleistungs-expression rekombinanter toxinproteine
EP2569018A4 (de) * 2010-05-14 2013-12-04 Philadelphia Children Hospital Humanisiertes ttc und verfahren zu seiner verwendung
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355094C3 (de) * 1973-11-03 1979-05-23 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tetanus-Impfstoffs

Also Published As

Publication number Publication date
US5389540A (en) 1995-02-14
ES2058821T3 (es) 1994-11-01
EP0430645A2 (de) 1991-06-05
DE69002817D1 (de) 1993-09-23
JPH03285681A (ja) 1991-12-16
EP0430645B1 (de) 1993-08-18
US5571694A (en) 1996-11-05
EP0430645A3 (en) 1992-01-08
DE69002817T2 (de) 1993-12-09
DK0430645T3 (da) 1993-10-11
JP3003211B2 (ja) 2000-01-24

Similar Documents

Publication Publication Date Title
DE69002817D1 (de) Vakzine.
ES2084030T3 (es) Expresion del fragmento c de la toxina del tetanos
DK0401844T3 (da) Resorberbare formlegemer og fremgangsmåde til fremstilling heraf
DK0652758T3 (da) Diferitoxin-vacciner
BR8707165A (pt) Processo de operacao de uma maquina formadora de vidro,processo de operacao de um sistema de producao de vidro e sistema de producao de vidro
DK0382173T3 (da) Substans PF 1022, fremgangsmåde til fremstilling heraf og anthelmintisk præparat indeholdende denne
DE69015504D1 (de) Stickstoffgasherstellungsverfahren.
DE3883312D1 (de) Maschine zum herstellen von glasgegenstaenden.
NO892117D0 (no) Pulserende infraroed straalingskilde.
DE3679078D1 (de) Photomaskenherstellungsverfahren.
FI945626A0 (fi) Menetelmä 2,2-difluoriketeenisilyyliasetaalien ja alfa, alfa-difluori-beta-silyylioksi-1,3-dioksolaani-4-propaanihappoestereiden valmistamiseksi
DE3886537D1 (de) Herstellung eines halbleitergrundmaterials.
PT87065A (pt) Process for the preparation of a vaccine against pasteurellosis
MX9200793A (es) Tetrahidropirinas y metodo para su preparacion.
ES2087129T3 (es) Sintesis enantioselectiva de antifoliatos.
FI913864L (fi) Produktionsprocess.
ES2054986T3 (es) N-arilacion de isatinas.
PT86619A (pt) Process for preparing alkylmelatonins
DK451888D0 (da) C12-modificerede erythromycin-a-derivater og fremgangsmaade til fremstilling deraf samt forbindelser til anvendelse som udgangsmateriale ved fremgangsmaaden
DE69002957D1 (de) Vakuum-Destillationsverfahren.
FI102083B (fi) Menetelmä L-karnitiinin valmistamiseksi epäjatkuvasti mikrobiologista tietä
DE69003963D1 (de) Vakuum-Destillationsverfahren.
FI911282L (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten 3,4-dihydroksi-2,5-dihydrofuranonien valmistamiseksi
EP0422523A3 (en) Process for the preparation of cyclic carbonates
IT9047986A0 (it) Macchina filatrice-spolatrice per la produzione di filato di fiocco.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time