ES2084030T3 - Expresion del fragmento c de la toxina del tetanos - Google Patents

Expresion del fragmento c de la toxina del tetanos

Info

Publication number
ES2084030T3
ES2084030T3 ES90909052T ES90909052T ES2084030T3 ES 2084030 T3 ES2084030 T3 ES 2084030T3 ES 90909052 T ES90909052 T ES 90909052T ES 90909052 T ES90909052 T ES 90909052T ES 2084030 T3 ES2084030 T3 ES 2084030T3
Authority
ES
Spain
Prior art keywords
fragment
expression
tetanus toxin
tetanus
toxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909052T
Other languages
English (en)
Inventor
Neil Fraser Fairweather
Andrew Joseph Makoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Pharma Ltd
Original Assignee
Evans Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evans Medical Ltd filed Critical Evans Medical Ltd
Application granted granted Critical
Publication of ES2084030T3 publication Critical patent/ES2084030T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN PROCESO PARA LA PRODUCCION DEL FRAGMENTO C DE LA TOXINA DEL TETANOS.
ES90909052T 1989-06-20 1990-06-20 Expresion del fragmento c de la toxina del tetanos Expired - Lifetime ES2084030T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898914122A GB8914122D0 (en) 1989-06-20 1989-06-20 Polypeptide expression

Publications (1)

Publication Number Publication Date
ES2084030T3 true ES2084030T3 (es) 1996-05-01

Family

ID=10658724

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909052T Expired - Lifetime ES2084030T3 (es) 1989-06-20 1990-06-20 Expresion del fragmento c de la toxina del tetanos

Country Status (9)

Country Link
US (1) US5443966A (es)
EP (1) EP0478602B1 (es)
JP (1) JP2981286B2 (es)
AT (1) ATE132532T1 (es)
DE (1) DE69024652T2 (es)
DK (1) DK0478602T3 (es)
ES (1) ES2084030T3 (es)
GB (1) GB8914122D0 (es)
WO (1) WO1990015871A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5601826A (en) * 1989-06-30 1997-02-11 The United States Of America As Represented By The Department Of Health And Human Services Peptide which produces protective immunity against tetanus
GB9209118D0 (en) 1992-04-28 1992-06-10 Sb 120 Amsterdam Bv Vaccine compositions
AU4545393A (en) * 1992-06-30 1994-01-24 United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Peptide which produces protective immunity against tetanus
CA2141427C (en) 1992-07-31 2008-07-22 Mohammed Anjam Khan Expression of recombinant fusion proteins in attenuated bacteria
GB9401787D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccine compositions
EP0876401B1 (en) * 1996-01-22 2007-06-13 Curis, Inc. Methods for producing op-1 morphogen analogs
US20030185792A1 (en) * 1996-01-22 2003-10-02 Curis, Inc. Morphogen analogs of bone morphogenic proteins
CA2216425C (en) 1996-03-23 2003-08-12 The Research Foundation For Microbial Diseases Of Osaka University Tetanus toxin functional fragment antigen and tetanus vaccine
US5958469A (en) * 1997-05-14 1999-09-28 Eastman Kodak Company Method for fabricating tools for molding diffractive surfaces on optical lenses
US7923216B2 (en) 1997-08-14 2011-04-12 Institut Pasteur In vivo modulation of neuronal transport
EP1681300A1 (en) * 1997-08-14 2006-07-19 Institut Pasteur Hybrid tetanus toxoid proteins that migrate retrogradely and transynaptically into the CNS
US20100081197A1 (en) * 1997-08-14 2010-04-01 Sylvie Roux In vivo modulation of neuronal transport
EP1296715B2 (en) 2000-06-29 2015-12-23 SmithKline Beecham Biologicals S.A. Multivalent vaccine composition
GB0108364D0 (en) 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
US20070105799A1 (en) * 2002-09-10 2007-05-10 Vical Incorporated Codon-optimized polynucleotide-based vaccines against Bacillus anthracis infection
BRPI0411854A (pt) * 2003-06-23 2006-08-29 Baxter Int veìculos protéicos para vacinas
US20070092449A1 (en) * 2005-04-05 2007-04-26 Rafael Vazquez-Martinez Methods for direct visualization of active synapses
EP1790358A1 (en) * 2005-11-23 2007-05-30 Université de Reims Champagne-Ardennes Protein constructs designed for targeting and lysis of cells
PL2066344T3 (pl) 2006-09-07 2011-10-31 Glaxosmithkline Biologicals Sa Skojarzona szczepionka zawierająca inaktywowany wirus polio
EP2142211A1 (en) 2007-05-02 2010-01-13 GlaxoSmithKline Biologicals S.A. Vaccine
EP2553102B1 (en) 2010-03-30 2015-12-09 Pfenex Inc. High level expression of recombinant toxin proteins
EP2569018A4 (en) 2010-05-14 2013-12-04 Philadelphia Children Hospital HUMANIZED TTC AND METHOD FOR ITS USE
GB201105981D0 (en) 2011-04-08 2011-05-18 Glaxosmithkline Biolog Sa Novel process
EP2788021B1 (en) 2011-12-09 2017-01-18 Bavarian Nordic A/S Poxvirus vector for the expression of bacterial antigens linked to tetanus toxin fragment c
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
NZ630868A (en) 2013-03-08 2017-02-24 Janssen Vaccines & Prevention Bv Acellular pertussis vaccine
KR20170044093A (ko) 2014-07-02 2017-04-24 스페리움 바이오메드 에스.엘. 무독성 파상풍 독소 c 단편(ttc)을 사용하여 근육량을 증가시키는 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355094C3 (de) * 1973-11-03 1979-05-23 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tetanus-Impfstoffs
GB8516442D0 (en) * 1985-06-28 1985-07-31 Wellcome Found Cloned antigen

Also Published As

Publication number Publication date
US5443966A (en) 1995-08-22
DE69024652T2 (de) 1996-05-15
DE69024652D1 (de) 1996-02-15
ATE132532T1 (de) 1996-01-15
EP0478602B1 (en) 1996-01-03
DK0478602T3 (da) 1996-02-05
GB8914122D0 (en) 1989-08-09
JP2981286B2 (ja) 1999-11-22
JPH04506005A (ja) 1992-10-22
EP0478602A1 (en) 1992-04-08
WO1990015871A1 (en) 1990-12-27

Similar Documents

Publication Publication Date Title
ES2084030T3 (es) Expresion del fragmento c de la toxina del tetanos
DE69002817T2 (de) Vakzine.
ES2046996T3 (es) Procedimiento para purificar organofosfitos terciarios.
ES8701723A1 (es) Procedimiento para preparar 2,2,6,6-tetraalquil-4-piperidilaminas
ES492384A0 (es) Un procedimiento de produccion de productos de fermentacion hipocolesteremicos.
FR2656300B1 (fr) Procede de production de phenol.
BE890047A (fr) Procede de production de gaz.
FR2593175B1 (fr) Procede de production de 3-phenyl-4-cyanopyrroles.
DE69015504T2 (de) Stickstoffgasherstellungsverfahren.
MX9201563A (es) Dexilosilbenanomicina b y procedimiento para prepararla.
DE69018537D1 (de) Zweistufiges Verfahren zum Herstellen starker, dünner Schlauchblasfolien.
IT1208045B (it) Procedimento per la fabbricazione di un semilavorato per la produizone di mutande con unamacchina circolare per maglieria, calzetteria o simile.
ES2023560A6 (es) Procedimiento para la produccion de hidrato de cefradina y solvato de cefradina y dimetilformamida.
IT8221204A0 (it) Apparecchio per la produzione di un filato ad effetto.
IT7827395A0 (it) Processo per la produzione di coke da materiale cellulosico e combustibili prodotti dallo stesso.
FR2310336A1 (fr) Procede de production d'un 4-hydroxybenzaldehyde disubstitue en 3,5 par formylation d'un butylphenol disubstitue en 2,6
ES521281A0 (es) Procedimiento de produccion del aspartamo por sintesis.
ES8102092A1 (es) Procedimiento de preparacion de monohidrato de 1,25-dihidro-xi-colecalciferol
FR2656869B1 (fr) Procede de production de methylpolysilanes et methylpolysilanes obtenus par ce procede.
ES2044144T3 (es) Nuevo procedimiento para la produccion de 4,6-dimetil-7-hidroxinonan-3-ona.
IT1180735B (it) Procedimento per la produzione di talloni sulle calze,specialmente sui peduli
SU649769A1 (ru) Способ модификации вискозной нити
BE846888A (fr) Procede de production d'ethylphenol,
ES511916A0 (es) Un metodo de produccion del antibiotico narasina.
ES529479A0 (es) Un procedimiento para producir un compuesto de antraciclina

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 478602

Country of ref document: ES