FI945626A0 - Menetelmä 2,2-difluoriketeenisilyyliasetaalien ja alfa, alfa-difluori-beta-silyylioksi-1,3-dioksolaani-4-propaanihappoestereiden valmistamiseksi - Google Patents

Menetelmä 2,2-difluoriketeenisilyyliasetaalien ja alfa, alfa-difluori-beta-silyylioksi-1,3-dioksolaani-4-propaanihappoestereiden valmistamiseksi

Info

Publication number
FI945626A0
FI945626A0 FI945626A FI945626A FI945626A0 FI 945626 A0 FI945626 A0 FI 945626A0 FI 945626 A FI945626 A FI 945626A FI 945626 A FI945626 A FI 945626A FI 945626 A0 FI945626 A0 FI 945626A0
Authority
FI
Finland
Prior art keywords
alpha
difluoro
acetals
silyloxy
dioxolane
Prior art date
Application number
FI945626A
Other languages
English (en)
Swedish (sv)
Other versions
FI945626A (fi
FI115461B (fi
Inventor
Thomas Charles Britton
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI945626A0 publication Critical patent/FI945626A0/fi
Publication of FI945626A publication Critical patent/FI945626A/fi
Application granted granted Critical
Publication of FI115461B publication Critical patent/FI115461B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FI945626A 1993-11-30 1994-11-29 Menetelmä 2,2-difluoriketeenisilyyliasetaalien ja alfa, alfa-difluori- beta-silyylioksi-1,3-dioksolaani-4-propaanihappoestereiden valmistamiseksi FI115461B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16054993A 1993-11-30 1993-11-30
US16054993 1993-11-30
US30712294A 1994-09-16 1994-09-16
US30712294 1994-09-16

Publications (3)

Publication Number Publication Date
FI945626A0 true FI945626A0 (fi) 1994-11-29
FI945626A FI945626A (fi) 1995-05-31
FI115461B FI115461B (fi) 2005-05-13

Family

ID=26856978

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945626A FI115461B (fi) 1993-11-30 1994-11-29 Menetelmä 2,2-difluoriketeenisilyyliasetaalien ja alfa, alfa-difluori- beta-silyylioksi-1,3-dioksolaani-4-propaanihappoestereiden valmistamiseksi

Country Status (14)

Country Link
US (1) US5618951A (fi)
EP (1) EP0655454B1 (fi)
JP (1) JP3615253B2 (fi)
KR (2) KR100344363B1 (fi)
AT (1) ATE204283T1 (fi)
BR (1) BR9404776A (fi)
CA (1) CA2136788C (fi)
DE (1) DE69427955T2 (fi)
DK (1) DK0655454T3 (fi)
ES (1) ES2159296T3 (fi)
FI (1) FI115461B (fi)
HU (2) HU224710B1 (fi)
IL (1) IL111793A (fi)
PT (1) PT655454E (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001994A (en) * 1995-12-13 1999-12-14 Eli Lilly And Company Process for making gemcitabine hydrochloride
US5756775A (en) * 1995-12-13 1998-05-26 Eli Lilly And Company Process to make α,α-difluoro-β-hydroxyl thiol esters
AU1289697A (en) 1995-12-13 1997-07-03 Eli Lilly And Company Alpha, alpha-difluoro-beta-hydroxy thiol esters and their synthesis
US7067600B2 (en) * 2001-08-16 2006-06-27 The Goodyear Tire & Rubber Company Modified silane compounds
KR100578616B1 (ko) * 2004-07-23 2006-05-10 한미약품 주식회사 Ｄ-에리트로-2,2-다이플루오로-2-데옥시-1-옥소라이보스화합물의 제조방법
CA2666746C (en) * 2006-11-03 2014-10-14 Basf Se Process for preparing difluoromethylpyrazolyl carboxylates
JP2010513411A (ja) * 2006-12-21 2010-04-30 ビーエーエスエフ ソシエタス・ヨーロピア フルオロメチル置換複素環式化合物の調製方法
EA019427B1 (ru) 2008-02-29 2014-03-31 Басф Се Способ получения алкил 2-алкоксиметилен-4,4-дифтор-3-оксобутиратов
KR20110004891A (ko) 2008-05-02 2011-01-14 바스프 에스이 2-(아미노메틸리덴)-4,4-디플루오로-3-옥소부티르산 에스테르의 제조 방법
WO2009133179A2 (de) * 2008-05-02 2009-11-05 Basf Se Verfahren zur herstellung halogensubstituierter 2-(aminomethyliden)-3-oxobuttersäureester
UA106470C2 (uk) * 2008-05-05 2014-09-10 Басф Се Спосіб одержання 1,3,4-заміщених піразольних сполук
ES2409605T3 (es) 2008-05-08 2013-06-27 Basf Se Procedimiento para la producción de arilcarboxamidas
CN102099343B (zh) * 2008-07-21 2014-06-04 巴斯夫欧洲公司 制备1,3-二取代的吡唑羧酸酯的方法
JP5540776B2 (ja) * 2010-03-05 2014-07-02 セントラル硝子株式会社 ジフルオロ酢酸エステルの製造方法
CN113603669A (zh) * 2021-08-06 2021-11-05 江苏八巨药业有限公司 一种吉西他滨关键中间体的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4417034A (en) * 1981-06-30 1983-11-22 E. I. Du Pont De Nemours & Co. Living polymers and process for their preparation
US4508880A (en) * 1981-06-30 1985-04-02 E. I. Du Pont De Nemours And Company "Living" polymers and process for their preparation
US4414372A (en) * 1982-06-17 1983-11-08 E. I. Du Pont De Nemours & Co. Process for preparing living polymers
US4482729A (en) * 1984-03-04 1984-11-13 Daikin Kogyo Co., Ltd. Fluoroalkyl silyl ketene acetals and a process for preparing the same
US4780554A (en) * 1984-11-20 1988-10-25 Union Carbide Corporation O-silylated ketene acetals and enol ethers and method of preparation
US4754046A (en) * 1987-06-25 1988-06-28 Dow Corning Corporation Stabilized silyl ketene acetals
US4824981A (en) * 1987-07-06 1989-04-25 Dow Corning Corporation Process to produce silyl ketene acetals
US4746750A (en) * 1987-08-31 1988-05-24 Dow Corning Corporation Synthesis of silyl ketene acetal from allyl 2-organoacrylates
JP2594605B2 (ja) * 1988-03-12 1997-03-26 鹿島石油株式会社 光学活性なα，α−ジフルオロ−β−ヒドロキシカルボニル化合物
JPH0267250A (ja) * 1988-09-02 1990-03-07 Asahi Glass Co Ltd ２，２‐ジフルオロ‐３‐ヒドロキシカルボン酸誘導体の製造法
US4824980A (en) * 1988-09-02 1989-04-25 Dow Corning Corporation Process to produce O-silyl O,N-ketene acetals
US5041587A (en) * 1989-02-14 1991-08-20 Mitsui Toatsu Chemicals, Inc. Process for preparing organic silicon compound
JPH02270841A (ja) * 1989-04-12 1990-11-05 Asahi Glass Co Ltd ２，２―ジフルオロ―３，４，５―トリヒドロキシカルボン酸誘導体の製造法

Also Published As

Publication number Publication date
HUT70178A (en) 1995-09-28
FI945626A (fi) 1995-05-31
JP3615253B2 (ja) 2005-02-02
KR950014125A (ko) 1995-06-15
FI115461B (fi) 2005-05-13
IL111793A0 (en) 1995-01-24
CA2136788A1 (en) 1995-05-31
KR100344363B1 (ko) 2002-11-30
CA2136788C (en) 2005-01-25
DE69427955D1 (de) 2001-09-20
EP0655454B1 (en) 2001-08-16
DE69427955T2 (de) 2002-04-18
IL111793A (en) 1998-12-06
EP0655454A1 (en) 1995-05-31
HU9904356D0 (en) 2000-02-28
HU219466B (hu) 2001-04-28
ATE204283T1 (de) 2001-09-15
BR9404776A (pt) 1995-11-21
PT655454E (pt) 2001-12-28
US5618951A (en) 1997-04-08
KR100332322B1 (ko) 2002-04-13
HU9403423D0 (en) 1995-02-28
HU224710B1 (en) 2006-01-30
ES2159296T3 (es) 2001-10-01
JPH07188260A (ja) 1995-07-25
DK0655454T3 (da) 2001-10-08

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