DE69331733T2 - Rekombinantes vielwertiges m-protein-vakzin - Google Patents

Rekombinantes vielwertiges m-protein-vakzin

Info

Publication number
DE69331733T2
DE69331733T2 DE69331733T DE69331733T DE69331733T2 DE 69331733 T2 DE69331733 T2 DE 69331733T2 DE 69331733 T DE69331733 T DE 69331733T DE 69331733 T DE69331733 T DE 69331733T DE 69331733 T2 DE69331733 T2 DE 69331733T2
Authority
DE
Germany
Prior art keywords
recombinant
protein vaccine
versatile
vaccine
evoke
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331733T
Other languages
English (en)
Other versions
DE69331733D1 (de
Inventor
B Dale
W Lederer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Tennessee Research Foundation
Original Assignee
University of Tennessee Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Tennessee Research Foundation filed Critical University of Tennessee Research Foundation
Application granted granted Critical
Publication of DE69331733D1 publication Critical patent/DE69331733D1/de
Publication of DE69331733T2 publication Critical patent/DE69331733T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69331733T 1992-09-16 1993-09-15 Rekombinantes vielwertiges m-protein-vakzin Expired - Fee Related DE69331733T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94595492A 1992-09-16 1992-09-16
PCT/US1993/008703 WO1994006421A1 (en) 1992-09-16 1993-09-15 Recombinant multivalent m protein vaccine

Publications (2)

Publication Number Publication Date
DE69331733D1 DE69331733D1 (de) 2002-04-25
DE69331733T2 true DE69331733T2 (de) 2002-08-22

Family

ID=25483752

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331733T Expired - Fee Related DE69331733T2 (de) 1992-09-16 1993-09-15 Rekombinantes vielwertiges m-protein-vakzin

Country Status (10)

Country Link
US (1) US6063386A (de)
EP (1) EP0625043B1 (de)
AT (1) ATE214601T1 (de)
AU (1) AU5128493A (de)
CA (1) CA2123579C (de)
DE (1) DE69331733T2 (de)
DK (1) DK0625043T3 (de)
ES (1) ES2170075T3 (de)
IL (1) IL107025A0 (de)
WO (1) WO1994006421A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6737521B1 (en) * 1990-05-11 2004-05-18 The Rockefeller University Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria
AU5128593A (en) * 1992-09-16 1994-04-12 University Of Tennessee Research Corporation, The Antigen of hybrid m protein and carrier for group a streptococcal vaccine
EP0625043B1 (de) * 1992-09-16 2002-03-20 The University Of Tennessee Research Corporation Rekombinantes vielwertiges m-protein-vakzin
AU3651595A (en) * 1994-09-21 1996-04-09 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Drug for the prevention and treatment of auto-immune and viral diseases, and diagnostic agents for detecting said diseases
AUPM885194A0 (en) * 1994-10-14 1994-11-10 Council Of The Queensland Institute Of Medical Research, The Synthetic peptides and vaccines comprising same
US6287574B1 (en) * 1995-03-17 2001-09-11 Biochem Pharma Inc. Proteinase K resistant surface protein of neisseria meningitidis
US5846547A (en) * 1996-01-22 1998-12-08 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
US6355255B1 (en) 1998-12-07 2002-03-12 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
EP1801217A1 (de) * 1997-09-12 2007-06-27 The University of Tennessee Research Foundation Streptokokken-Impfstoffgruppe
EP1003875B1 (de) * 1997-09-12 2006-12-27 University of Tennessee Research Foundation Gruppe a streptokokken-impfstoff
US6716433B1 (en) 1997-09-12 2004-04-06 University Of Tennessee Research Foundation Group a streptococcal vaccines
US6541011B2 (en) * 1998-02-11 2003-04-01 Maxygen, Inc. Antigen library immunization
AU762100B2 (en) * 1998-12-22 2003-06-19 University Of Tennessee Research Corporation, The Protective antigen of group A Streptococci (SPA)
US7063850B1 (en) 1998-12-22 2006-06-20 University Of Tennessee Research Foundation Protective antigen of group A Streptococci
US7256265B2 (en) 1999-12-03 2007-08-14 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
DK1294771T3 (da) * 2000-06-12 2008-12-15 Univ Saskatchewan Kimært GapC-protein fra Streptococcus og anvendelse deraf til vaccinering og diagnosticering
US7160547B2 (en) 2000-10-10 2007-01-09 University Of Tennessee Research Corporation Streptococcal streptolysin S vaccines
WO2002057315A2 (en) * 2000-10-10 2002-07-25 University Of Tennessee Research Corporation Streptococcal streptolysin s vaccines
EP2025754A3 (de) * 2001-05-15 2009-05-13 ID Biomedical Corporation Antigene von Moraxella (Branhamella) catarrhalis
AU2011232787B2 (en) * 2001-05-18 2013-05-02 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention, Technology Transfer Office Peptide vaccines against group A streptococci
AU2008203277B2 (en) * 2001-05-18 2011-07-07 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention, Technology Transfer Office Peptide vaccines against group A streptococci
CA2881980A1 (en) 2001-05-18 2002-11-28 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention, Technology Transfer Office Peptide vaccines against group a streptococci
AU2002365184A1 (en) 2001-10-26 2003-07-30 Id Biomedical Corporation Of Washington Efficient protein expression system
EP1572941A4 (de) 2002-02-26 2009-03-18 Maxygen Inc Neue flavivirus-antigene
US7255867B2 (en) * 2002-11-15 2007-08-14 Id Biomedical Corporation Of Quebec Vaccine
US20040151737A1 (en) * 2003-02-05 2004-08-05 University Of Tennessee Streptococcal serum opacity factors and fibronectin-binding proteins and peptides thereof for the treatment and detection of streptococcal infection
US20070110763A1 (en) * 2003-08-15 2007-05-17 Stephane Rioux Polypeptides of streptococcus pyogenes
EP1864996A1 (de) * 2006-06-06 2007-12-12 Helmholtz-Zentrum für Infektionsforschung GmbH Peptid das mit rheumatischem Fieber verbunden ist und dessen Verwendung als diagnostischer Marker.
US9289485B2 (en) * 2006-11-30 2016-03-22 Luiza Guilherme Guglielmi Therapeutic application of S. pyogenes C-terminal peptide
BRPI0604997A (pt) * 2006-11-30 2007-05-22 Fundacao Zerbini vacina contra o estreptococo beta hemolìtico do grupo a, e respectivo processo de obtenção
EP2144924B1 (de) * 2007-04-16 2016-05-11 MinervaX Aps Fusionsproteinimpfstoff
BRPI0815008B8 (pt) * 2007-08-02 2021-05-25 Biondvax Pharmaceuticals Ltd vacinas multiméricas com múltiplos epítopos contra influenza
AR074273A1 (es) 2008-11-05 2011-01-05 Wyeth Corp Composicion inmunigenica de multiples componentes para la prevencion de la enfermedad estreptococica beta-hemolitica bhs. uso. metodo
AU2011360572B2 (en) 2011-02-22 2017-03-02 Biondvax Pharmaceuticals Ltd. Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
CN103648526A (zh) 2011-06-17 2014-03-19 田纳西大学研究基金会 A群链球菌多价疫苗
US9650425B2 (en) 2013-02-11 2017-05-16 University Of Tennessee Research Foundation Group A streptococcal M-related proteins and methods of use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284537A (en) * 1980-07-03 1981-08-18 The United States Of America As Represented By The Department Of Health And Human Services Conjugate of streptococcal M protein peptide vaccine
US4454121A (en) * 1982-07-27 1984-06-12 The University Of Tennessee Research Corporation Synthetic peptides corresponding to antigenic determinants of the M protein of Streptococcus pyogenes
US4597967A (en) * 1982-07-27 1986-07-01 The University Of Tennessee Research Corp. Synthetic polypeptide fragments
US4521334A (en) * 1982-07-27 1985-06-04 The University Of Tennesse Research Corporation Synthetic polypeptide fragments
US4919930A (en) * 1983-06-10 1990-04-24 University Of Tennessee Research Corporation Synthetic M proteins-streptococci type 5
US4784948A (en) * 1983-08-10 1988-11-15 The Rockefeller University Production of streptococcal m protein immunogens and molecular probes
US4705684A (en) * 1985-05-31 1987-11-10 The University Of Tennessee Research Corporation Synthetic M proteins - streptococci type 6
US5124153A (en) * 1987-08-24 1992-06-23 University Of Tennessee Research Corp. Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products
WO1993021220A1 (en) * 1992-04-08 1993-10-28 The Council Of The Queensland Institute Of Medical Research Synthetic peptides useful in a vaccine against and in the diagnosis of streptococcal infection
EP0625043B1 (de) * 1992-09-16 2002-03-20 The University Of Tennessee Research Corporation Rekombinantes vielwertiges m-protein-vakzin

Also Published As

Publication number Publication date
EP0625043A4 (en) 1997-05-21
ES2170075T3 (es) 2002-08-01
DK0625043T3 (da) 2002-04-22
CA2123579A1 (en) 1994-03-31
CA2123579C (en) 2005-05-10
AU5128493A (en) 1994-04-12
WO1994006421A1 (en) 1994-03-31
IL107025A0 (en) 1993-12-28
EP0625043B1 (de) 2002-03-20
EP0625043A1 (de) 1994-11-23
DE69331733D1 (de) 2002-04-25
ATE214601T1 (de) 2002-04-15
US6063386A (en) 2000-05-16

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee