DE1944255B - - Google Patents

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Publication number

DE1944255B

DE1944255B DE1944255B DE 1944255 B DE1944255 B DE 1944255B DE 1944255 B DE1944255 B DE 1944255B

Authority

DE

Germany

Prior art keywords

day

minutes

exposure time

test

cooh

Prior art date

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

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• 150000001875 compounds Chemical class 0.000 claims description 17
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 10
• 125000000896 monocarboxylic acid group Chemical group 0.000 claims description 4
• QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 12
• 230000000721 bacterilogical effect Effects 0.000 description 12
• 239000000243 solution Substances 0.000 description 11
• HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
• 239000000126 substance Substances 0.000 description 9
• 239000004480 active ingredient Substances 0.000 description 8
• 108090000623 proteins and genes Proteins 0.000 description 7
• 102000004169 proteins and genes Human genes 0.000 description 7
• 241000588724 Escherichia coli Species 0.000 description 6
• 241000588767 Proteus vulgaris Species 0.000 description 6
• 241000589517 Pseudomonas aeruginosa Species 0.000 description 6
• 241000191967 Staphylococcus aureus Species 0.000 description 6
• BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 6
• 229940007042 proteus vulgaris Drugs 0.000 description 6
• 239000000725 suspension Substances 0.000 description 6
• 239000007864 aqueous solution Substances 0.000 description 5
• 230000003115 biocidal effect Effects 0.000 description 5
• 238000006243 chemical reaction Methods 0.000 description 5
• 230000000622 irritating effect Effects 0.000 description 5
• 238000002360 preparation method Methods 0.000 description 5
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
• RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
• 241000283973 Oryctolagus cuniculus Species 0.000 description 4
• 150000001413 amino acids Chemical class 0.000 description 4
• 238000004519 manufacturing process Methods 0.000 description 4
• CNDHHGUSRIZDSL-UHFFFAOYSA-N 1-chlorooctane Chemical compound CCCCCCCCCl CNDHHGUSRIZDSL-UHFFFAOYSA-N 0.000 description 3
• ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 description 3
• KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
• DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
• YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
• 150000001412 amines Chemical class 0.000 description 3
• 230000000844 anti-bacterial effect Effects 0.000 description 3
• 239000012888 bovine serum Substances 0.000 description 3
• ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 3
• 229960004068 hexachlorophene Drugs 0.000 description 3
• 239000013558 reference substance Substances 0.000 description 3
• 239000000344 soap Substances 0.000 description 3
• 239000002904 solvent Substances 0.000 description 3
• RPNUMPOLZDHAAY-UHFFFAOYSA-N Diethylenetriamine Chemical compound NCCNCCN RPNUMPOLZDHAAY-UHFFFAOYSA-N 0.000 description 2
• OMOVVBIIQSXZSZ-UHFFFAOYSA-N [6-(4-acetyloxy-5,9a-dimethyl-2,7-dioxo-4,5a,6,9-tetrahydro-3h-pyrano[3,4-b]oxepin-5-yl)-5-formyloxy-3-(furan-3-yl)-3a-methyl-7-methylidene-1a,2,3,4,5,6-hexahydroindeno[1,7a-b]oxiren-4-yl] 2-hydroxy-3-methylpentanoate Chemical compound CC12C(OC(=O)C(O)C(C)CC)C(OC=O)C(C3(C)C(CC(=O)OC4(C)COC(=O)CC43)OC(C)=O)C(=C)C32OC3CC1C=1C=COC=1 OMOVVBIIQSXZSZ-UHFFFAOYSA-N 0.000 description 2
• 239000002253 acid Substances 0.000 description 2
• 125000000217 alkyl group Chemical group 0.000 description 2
• 230000001580 bacterial effect Effects 0.000 description 2
• 230000015572 biosynthetic process Effects 0.000 description 2
• FOCAUTSVDIKZOP-UHFFFAOYSA-N chloroacetic acid Chemical compound OC(=O)CCl FOCAUTSVDIKZOP-UHFFFAOYSA-N 0.000 description 2
• 229940106681 chloroacetic acid Drugs 0.000 description 2
• MVPPADPHJFYWMZ-UHFFFAOYSA-N chlorobenzene Chemical compound ClC1=CC=CC=C1 MVPPADPHJFYWMZ-UHFFFAOYSA-N 0.000 description 2
• 238000004140 cleaning Methods 0.000 description 2
• 239000000645 desinfectant Substances 0.000 description 2
• 230000000249 desinfective effect Effects 0.000 description 2
• 239000003599 detergent Substances 0.000 description 2
• 238000010790 dilution Methods 0.000 description 2
• 239000012895 dilution Substances 0.000 description 2
• 230000000694 effects Effects 0.000 description 2
• 101150073877 egg-1 gene Proteins 0.000 description 2
• 238000000921 elemental analysis Methods 0.000 description 2
• 238000002474 experimental method Methods 0.000 description 2
• 238000005187 foaming Methods 0.000 description 2
• 239000012535 impurity Substances 0.000 description 2
• 230000007794 irritation Effects 0.000 description 2
• 231100000286 mucous membrane, eye irritation or corrosion testing Toxicity 0.000 description 2
• -1 octyl halide Chemical class 0.000 description 2
• 238000010992 reflux Methods 0.000 description 2
• 210000002966 serum Anatomy 0.000 description 2
• FDRCDNZGSXJAFP-UHFFFAOYSA-M sodium chloroacetate Chemical compound [Na+].[O-]C(=O)CCl FDRCDNZGSXJAFP-UHFFFAOYSA-M 0.000 description 2
• 239000007787 solid Substances 0.000 description 2
• BASMANVIUSSIIM-UHFFFAOYSA-N 1-chloro-2-(chloromethyl)benzene Chemical compound ClCC1=CC=CC=C1Cl BASMANVIUSSIIM-UHFFFAOYSA-N 0.000 description 1
• 101150021183 65 gene Proteins 0.000 description 1
• 241000894006 Bacteria Species 0.000 description 1
• 241000283690 Bos taurus Species 0.000 description 1
• CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
• 241000195493 Cryptophyta Species 0.000 description 1
• 241000233866 Fungi Species 0.000 description 1
• 235000019687 Lamb Nutrition 0.000 description 1
• 241001465754 Metazoa Species 0.000 description 1
• CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
• 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
• 241000191940 Staphylococcus Species 0.000 description 1
• 241000700605 Viruses Species 0.000 description 1
• 239000000370 acceptor Substances 0.000 description 1
• 150000001242 acetic acid derivatives Chemical class 0.000 description 1
• 150000001298 alcohols Chemical class 0.000 description 1
• 150000001350 alkyl halides Chemical class 0.000 description 1
• 150000003978 alpha-halocarboxylic acids Chemical class 0.000 description 1
• 244000052616 bacterial pathogen Species 0.000 description 1
• 239000003899 bactericide agent Substances 0.000 description 1
• 235000015278 beef Nutrition 0.000 description 1
• 238000009835 boiling Methods 0.000 description 1
• 239000000872 buffer Substances 0.000 description 1
• 125000002091 cationic group Chemical group 0.000 description 1
• 239000007795 chemical reaction product Substances 0.000 description 1
• 230000000052 comparative effect Effects 0.000 description 1
• 238000001816 cooling Methods 0.000 description 1
• 239000002537 cosmetic Substances 0.000 description 1
• 239000006185 dispersion Substances 0.000 description 1
• 239000003814 drug Substances 0.000 description 1
• 229940079593 drug Drugs 0.000 description 1
• WBJINCZRORDGAQ-UHFFFAOYSA-N ethyl formate Chemical compound CCOC=O WBJINCZRORDGAQ-UHFFFAOYSA-N 0.000 description 1
• 239000006260 foam Substances 0.000 description 1
• 239000008233 hard water Substances 0.000 description 1
• 239000013067 intermediate product Substances 0.000 description 1
• 239000007788 liquid Substances 0.000 description 1
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
• 239000000203 mixture Substances 0.000 description 1
• 238000000199 molecular distillation Methods 0.000 description 1
• 210000004400 mucous membrane Anatomy 0.000 description 1
• YBUMEUMBIWOBBF-UHFFFAOYSA-N n'-[2-(octylamino)ethyl]ethane-1,2-diamine Chemical compound CCCCCCCCNCCNCCN YBUMEUMBIWOBBF-UHFFFAOYSA-N 0.000 description 1
• 229940072033 potash Drugs 0.000 description 1
• BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 1
• 235000015320 potassium carbonate Nutrition 0.000 description 1
• 238000004321 preservation Methods 0.000 description 1
• 239000012063 pure reaction product Substances 0.000 description 1
• 238000000746 purification Methods 0.000 description 1
• 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
• 239000000376 reactant Substances 0.000 description 1
• 239000011541 reaction mixture Substances 0.000 description 1
• 230000000717 retained effect Effects 0.000 description 1
• 239000008149 soap solution Substances 0.000 description 1
• 239000011734 sodium Substances 0.000 description 1
• 238000004659 sterilization and disinfection Methods 0.000 description 1
• 239000002602 strong irritant Substances 0.000 description 1
• 238000003786 synthesis reaction Methods 0.000 description 1
• 239000010409 thin film Substances 0.000 description 1
• 238000005406 washing Methods 0.000 description 1
• 238000010626 work up procedure Methods 0.000 description 1
• 239000008096 xylene Substances 0.000 description 1